Article Figures & Data
Figures
- FIGURE 1.
Photomicrographs of atherosclerotic lesions in thoracic aortas of control (A and B) and WHHL (C and D) rabbits. Azan-Mallory staining (A and C) and immunohistochemical staining with antimacrophage monoclonal antibody RAM-11 (B and D) are shown. Panel E is a magnified view of the area boxed in panel D. Macrophages can be seen (arrowheads) in serial sections from WHHL rabbits (C and D). Bars = 200 μm.
- FIGURE 2.
Correlation between 18F-FDG uptake and macrophage number in aortic segments (n = 86) (A) or between 18F-FDG uptake and the ratio of the area of the intima to the area of the whole cross section in aortic segments (n = 86) (B) from WHHL rabbits.
- FIGURE 3.
PET images (A and D), CT images (B and E), and superimposed PET/CT images (C and F) in the sagittal (I) and coronal (II) planes for WHHL (A, B, and C) and control (D, E, and F) rabbits. Orange arrows, orange arrowheads, and white arrowheads indicate aortas, kidneys, and livers, respectively.
Tables
Parameter Mean ± SD for indicated portion of aorta in following rabbits*: Control (n = 3) WHHL (n = 11) Abdominal Thoracic Abdominal Thoracic 18F-FDG uptake (DUR) 0.40 ± 0.11 0.44 ± 0.15 0.72 ± 0.37† 1.47 ± 0.90‡ Aortic segment-to-blood radioactivity ratio 1.06 ± 0.35 1.23 ± 0.34 1.77 ± 0.86§ 3.18 ± 1.19‡ No. of macrophages ND ND 254 ± 257 737 ± 486
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