Published Ahead of Print

November 12, 2021

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Glypican-3 targeted thorium-227 alpha therapy reduces tumor burden in an orthotopic xenograft murine model of hepatocellular carcinoma
Kevin P Labadie, Donald K Hamlin, Aimee Kenoyer, Sara K Daniel, Alan F Utria, Andrew D Ludwig, Heidi L Kenerson, Lily Li, Jonathan G Sham, Delphine L Chen, Johnnie J Orozco, Raymond S Yeung, Chris Orvig, Yawen Li, D Scott Wilbur and James O Park

Journal of Nuclear Medicine November 12, 2021, jnumed.121.262562; DOI: https://doi.org/10.2967/jnumed.121.262562
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Anti-Androgen Therapy Radiosensitizes Androgen Receptor Positive Cancers to F-18 Fluorodeoxyglucose
Indulekha Singaravelu, Henry Spitz, Mary Mahoney, Zhongyun Dong and Nalinikanth Kotagiri

Journal of Nuclear Medicine November 12, 2021, jnumed.121.262958; DOI: https://doi.org/10.2967/jnumed.121.262958
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A Novel Radiotracer for Molecular Imaging and Therapy of Gastrin-Releasing Peptide Receptor Positive Prostate Cancer
Ivica Jerolim Bratanovic, Chengcheng Zhang, Zhengxing Zhang, Hsiou-Ting Kuo, Nadine Colpo, Jutta Zeisler, Helen Merkens, Carlos Uribe, Kuo-Shyan Lin and François Bénard

Journal of Nuclear Medicine November 12, 2021, jnumed.120.257758; DOI: https://doi.org/10.2967/jnumed.120.257758
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⁶⁸Ga-PSMA PET/CT for response assessment and outcome prediction in metastatic prostate cancer patients treated with taxane-based chemotherapy
Qaid Ahmed Shagera, Carlos Artigas, Ioannis Karfis, Gabriela Critchi, Nieves Martinez Chanza, Spyridon Sideris, Alexandre Peltier, Marianne Paesmans, Thierry Gil and Patrick Flamen

Journal of Nuclear Medicine November 12, 2021, jnumed.121.263006; DOI: https://doi.org/10.2967/jnumed.121.263006
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Lung dose measured on post-radioembolization ⁹⁰Y-PET/CT and incidence of radiation pneumonitis
Martina Stella, Rob van Rooij, Marnix Lam, Hugo de Jong and Arthur Johannes Anthonius Theodorus Braat

Journal of Nuclear Medicine November 12, 2021, jnumed.121.263143; DOI: https://doi.org/10.2967/jnumed.121.263143
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The quest for an accurate functional tumor volume with ⁶⁸Ga-DOTATATE PET/CT
Ryan P Reddy, C Ross Schmidtlein, Romina G Giancipoli, Audre Mauguen, Daniel LaFontaine, Heiko Schoder and Lisa Bodei

Journal of Nuclear Medicine November 12, 2021, jnumed.121.262782; DOI: https://doi.org/10.2967/jnumed.121.262782

November 5, 2021

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Commercially competitive vendor-agnostic image reconstruction could be a leap forward for PET harmonization
Adam L. Kesner

Journal of Nuclear Medicine November 5, 2021, jnumed.121.263421; DOI: https://doi.org/10.2967/jnumed.121.263421
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Prognostic value of whole-body PET volumetric parameters extracted from ⁶⁸Ga-DOTATOC-PET/CT in well-differentiated neuroendocrine tumors
Philippe THUILLIER, Virginia LIBERINI, Serena GRIMALDI, Osvaldo RAMPADO, Elena GALLIO, Bruno DE SANTI, Emanuela ARVAT, Alessandro PIOVESAN, Roberto FILIPPI, Ronan ABGRAL, Filippo MOLINARI and Desiree DEANDREIS

Journal of Nuclear Medicine November 5, 2021, jnumed.121.262652; DOI: https://doi.org/10.2967/jnumed.121.262652
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Imaging PD-L1 expression in melanoma brain metastases
Sridhar Nimmagadda

Journal of Nuclear Medicine November 5, 2021, jnumed.121.263209; DOI: https://doi.org/10.2967/jnumed.121.263209
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PET with a ⁶⁸Ga-labeled FAPI dimer: moving towards theranostics
Muhsin H Younis, Xiaoli Lan and Weibo Cai

Journal of Nuclear Medicine November 5, 2021, jnumed.121.263292; DOI: https://doi.org/10.2967/jnumed.121.263292
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Nuclear Medicine and Artificial Intelligence: Best Practices for Algorithm Development
Tyler J. Bradshaw, Ronald Boellaard, Joyita Dutta, Abhinav K. Jha, Paul Jacobs, Quanzheng Li, Chi Liu, Arkadiusz Sitek, Babak Saboury, Peter J.H. Scott, Piotr J. Slomka, John J. Sunderland, Richard L. Wahl, Fereshteh Yousefirizi, Sven Zuehlsdorff, Arman Rahmim and Irène Buvat

Journal of Nuclear Medicine November 5, 2021, jnumed.121.262567; DOI: https://doi.org/10.2967/jnumed.121.262567
Open Access
Correlation of ⁶⁸Ga-FAPi-46 PET biodistribution with FAP expression by immunohistochemistry in patients with solid cancers: a prospective translational exploratory study
Christine E. Mona, Matthias R. Benz, Firas Hikmat, Tristan R. Grogan, Katharina Lückerath, Aria Razmaria, Rana Riahi, Roger Slavik, Mark D. Girgis, Giuseppe Carlucci, Kimberly A. Kelly, Samuel W French, Johannes Czernin, David W. Dawson and Jeremie Calais

Journal of Nuclear Medicine November 5, 2021, jnumed.121.262426; DOI: https://doi.org/10.2967/jnumed.121.262426

October 28, 2021

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Affibody-mediated PNA-based pretargeted co-treatment improves survival of trastuzumab-treated mice bearing HER2-expressing xenografts
Maryam Oroujeni, Hanna Tano, Anzhelika Vorobyeva, Yongsheng Liu, Olga Vorontsova, Tianqi Xu, Kristina Westerlund, Anna Orlova, Vladimir Tolmachev and Amelie Eriksson Karlström

Journal of Nuclear Medicine October 28, 2021, jnumed.121.262123; DOI: https://doi.org/10.2967/jnumed.121.262123
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Improved Prognosis of Treatment Failure in Cervical Cancer with Non-Tumor Positron Emission Tomography / Computed Tomography Radiomics
Tahir Yusufaly, Jingjing Zou, Tyler Nelson, Casey Williamson, Aaron Simon, Meenakshi Singhal, Hannah Liu, Hank Wong, Cheryl Saenz, Jyoti Mayadev, Michael McHale, Catherine Yashar, Ramez Eskander, Andrew Sharabi, Carl Hoh, Sebastian Obrzut and Loren Mell

Journal of Nuclear Medicine October 28, 2021, jnumed.121.262618; DOI: https://doi.org/10.2967/jnumed.121.262618
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Reply LTE, On Semi-quantitative Methods for Assessing Vascular ¹⁸FDG-PET Activity in Large-Vessel Vasculitis
Mark A Ahlman, Roberto Maass-Moreno and Peter C Grayson

Journal of Nuclear Medicine October 28, 2021, jnumed.121.263158; DOI: https://doi.org/10.2967/jnumed.121.263158
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Enhancing Radium 223 treatment efficacy by anti-beta 1 integrin targeting
Claudia Paindelli, Stefano Casarin, Feng Wang, Luis Diaz-Gomez, Jianhua Zhang, Antonios G Mikos, Christopher J Logothetis, Peter Friedl and Eleonora Dondossola

Journal of Nuclear Medicine October 28, 2021, jnumed.121.262743; DOI: https://doi.org/10.2967/jnumed.121.262743

October 21, 2021

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¹⁸F-FDG PET improves baseline clinical predictors of response in diffuse large B-cell lymphoma: The HOVON-84 study
Coreline N. Burggraaff, Jakoba J. Eertink, Pieternella J. Lugtenburg, Otto S. Hoekstra, Anne I.J. Arens, Bart de Keizer, Martijn W. Heymans, Bronno van der Holt, Sanne E. Wiegers, Simone Pieplenbosch, Ronald Boellaard, Henrica C.W. de Vet and Josée M. Zijlstra

Journal of Nuclear Medicine October 21, 2021, jnumed.121.262205; DOI: https://doi.org/10.2967/jnumed.121.262205
Open Access
Women Authors in Nuclear Medicine Journals: a Survey from 2014 to 2020
Charline LASNON, Gilles Girault, Rachida Lebtahi, Catherine Ansquer, Justine Lequesne and Elske Quak

Journal of Nuclear Medicine October 21, 2021, jnumed.121.262773; DOI: https://doi.org/10.2967/jnumed.121.262773
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Imaging in Post-COVID Lung Disease (PCLD): does [¹⁸F]-FDG-PET/CT have the Key?
Olivier Gheysens, Leïla Belkhir and François Jamar

Journal of Nuclear Medicine October 21, 2021, jnumed.121.263166; DOI: https://doi.org/10.2967/jnumed.121.263166
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Comparison of Exogenous Ketone Administration versus Dietary Carbohydrate Restriction on Myocardial Glucose Suppression: A Crossover Clinical Trial
Senthil Selvaraj, Kenneth Margulies, Supritha Dugyala, Erin Schubert, Ann Tierney, Zoltan Arany, Daniel A Pryma, Svati H Shah, Eduardo Rame, Daniel Kelly and Paco E Bravo

Journal of Nuclear Medicine October 21, 2021, jnumed.121.262734; DOI: https://doi.org/10.2967/jnumed.121.262734
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The History of Prostate-Specific Membrane Antigen as a Theranostic Target in Prostate Cancer: The Foundational Role of the Prostate Cancer Foundation
Andrea K Miyahira and Howard R Soule

Journal of Nuclear Medicine October 21, 2021, jnumed.121.262997; DOI: https://doi.org/10.2967/jnumed.121.262997

October 14, 2021

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Head-to-head comparison of ⁶⁸Ga-PSMA-11 PET/CT and mpMRI with histopathology gold-standard in the detection, intra-prostatic localization and local extension of primary prostate cancer: results from a prospective single-center imaging trial
Ida Sonni, Ely R Felker, Andrew T Lenis, Anthony E Sisk, Shadfar Bahri, Martin S Allen-Auerbach, Wesley Robert Armstrong, Voraparee Suvannarerg, Teeravut Tubtawee, Tristan Grogan, David Elashoff, Matthias Eiber, Staven S Raman, Johannes Czernin, Robert Reiter and Jérémie Calais

Journal of Nuclear Medicine October 14, 2021, jnumed.121.262398; DOI: https://doi.org/10.2967/jnumed.121.262398
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ER imaging for estrogen-related tumors is bothersome but useful
Hidehiko Okazawa

Journal of Nuclear Medicine October 14, 2021, jnumed.121.263170; DOI: https://doi.org/10.2967/jnumed.121.263170
Open Access
Lung scintigraphy for pulmonary embolism diagnosis in COVID-19 patients: a multicenter study.
Pierre-Yves Le Roux, Pierre-Benoit Bonnefoy, Achraf Bahloul, Benoit Denizot, Bertrand Barres, Caroline Moreau-Triby, Astrid Girma, Amandine Pallardy, Quentin Ceyrat, Laure Sarda-Mantel, Micheline Razzouk-Cadet, Reka Zsigmond, Cachin Florent, Gilles Karcher and Pierre-Yves Salaun

Journal of Nuclear Medicine October 14, 2021, jnumed.121.262955; DOI: https://doi.org/10.2967/jnumed.121.262955
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Perspective on Fibroblast Activation Protein Specific PET/CT Imaging in Fibrotic Interstitial Lung Diseases: Imaging Fibrosis - a New Paradigm for Molecular Imaging?
Christian Schmidkonz

Journal of Nuclear Medicine October 14, 2021, jnumed.121.262944; DOI: https://doi.org/10.2967/jnumed.121.262944
Open Access
PSMA PET validates higher rates of metastatic disease for European Association of Urology Biochemical Recurrence Risk Groups: an international multicenter study
Justin Ferdinandus, Wolfgang Peter Fendler, Andrea Farolfi, Samuel Washington, Osama Mohamad, Miguel Hernandez Pampaloni, Peter J Scott, Melissa Rodnick, Benjamin L Viglianti, Matthias Eiber, Ken Herrmann, Johannes Czernin, Wesley Robert Armstrong, Jeremie Calais, Thomas A. Hope and Morand A. Piert

Journal of Nuclear Medicine October 14, 2021, jnumed.121.262821; DOI: https://doi.org/10.2967/jnumed.121.262821
Open Access
Neuropsychological profiles and cerebral glucose metabolism in neurocognitive Long COVID-syndrome
Andrea Dressing, Tobias Bormann, Ganna Blazhenets, Nils Schroeter, Lea I Walter, Johannes Thurow, Dietrich August, Hanna Hilger, Katarina Stete, Kathrin Gerstacker, Susan Arndt, Alexander Rau, Horst Urbach, Siegbert Rieg, Dirk Wagner, Cornelius Weiller, Philipp T Meyer and Jonas A Hosp

Journal of Nuclear Medicine October 14, 2021, jnumed.121.262677; DOI: https://doi.org/10.2967/jnumed.121.262677
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Combined PARP1-targeted nuclear contrast and reflectance contrast enhances confocal microscopic detection of basal cell carcinoma
Aditi Sahu, Jose Cordero, Xiancheng Wu, Susanne Kossatz, Ucalene Harris, Paula Demetrio Desouza Franca, Nicholas R Kurtansky, Niasia Everett, Stephen Dusza, Jilliana Monnier, Piyush Kumar, Christi Alessi-Fox, Christian Brand, Sheryl Roberts, Kivanc Kose, William Phillip, Erica Lee, Chih-Shan Jason Chen, Anthony Rossi, Kishwer Nehal, Melissa Pulitzer, Caterina Longo, Allan Halpern, Thomas Reiner, Milind Rajadhyaksha and Manu Jain

Journal of Nuclear Medicine October 14, 2021, jnumed.121.262600; DOI: https://doi.org/10.2967/jnumed.121.262600

October 7, 2021

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¹⁸F-FDG PET/CT for post-treatment surveillance imaging of patients with stage III Merkel cell carcinoma
Sonia Mahajan, Christopher A. Barker, Audrey Mauguen, Sandra P. D'Angelo, Randy Yeh and Neeta Pandit-Taskar

Journal of Nuclear Medicine October 7, 2021, jnumed.121.262882; DOI: https://doi.org/10.2967/jnumed.121.262882
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Pitfalls and common findings in ⁶⁸Ga-FAPI-PET – A pictorial analysis
Lukas Kessler, Justin Ferdinandus, Nader Hirmas, Fadi Zarrad, Michael Nader, David Kersting, Manuel Weber, Sandra Kazek, Miriam Sraieb, Rainer Hamacher, Katharina Lueckerath, Lale Umutlu, Wolfgang P. Fendler and Christoph Rischpler

Journal of Nuclear Medicine October 7, 2021, jnumed.121.262808; DOI: https://doi.org/10.2967/jnumed.121.262808
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First-in-human brain PET imaging of the GluN2B-containing N-methyl-D-aspartate receptor with (R)-¹¹C-Me-NB1
Lucas Rischka, Chrysoula Vraka, Verena Pichler, Sazan Rasul, Lukas Nics, Gregor Gryglewski, Patricia Handschuh, Matej Murgas, Godber Godbersen, Leo Silberbauer, Jakob Unterholzner, Christoph Wotawa, Ahmed Haider, Hazem Ahmed, Roger Schibli, Thomas Mindt, Markus Mitterhauser, Wolfgang Wadsak, Andreas Hahn, Rupert Lanzenberger, Marcus Hacker and Simon M Ametamey

Journal of Nuclear Medicine October 7, 2021, jnumed.121.262427; DOI: https://doi.org/10.2967/jnumed.121.262427

September 30, 2021

Open Access
Feasibility of ultra-low ¹⁸F-FDG activity acquisitions using total-body PET/CT
Yan Hu, Guobing Liu, Haojun Yu, Ying Wang, Chenwei Li, Hui Tan, shuguang chen, Jianying Gu and Hongcheng Shi

Journal of Nuclear Medicine September 30, 2021, jnumed.121.262038; DOI: https://doi.org/10.2967/jnumed.121.262038
Open Access
The Added Value of ⁶⁸Ga-FAPI-04 PET/CT in Patients with Head and Neck Cancer of Unknown Primary with ¹⁸F-FDG Negative Findings
Bingxin Gu, Xiaoping Xu, Ji Zhang, Xiaomin Ou, Zuguang Xia, Qing Guan, Silong Hu, Zhongyi Yang and Shaoli Song

Journal of Nuclear Medicine September 30, 2021, jnumed.121.262790; DOI: https://doi.org/10.2967/jnumed.121.262790
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Appropriate Use Criteria for Prostate-Specific Membrane Antigen PET Imaging
Hossein Jadvar, Jérémie Calais, Stefano Fanti, Felix Feng, Kirsten L. Greene, James L. Gulley, Michael Hofman, Bridget F. Koontz, Daniel W. Lin, Michael J. Morris, Steve P. Rowe, Trevor J. Royce, Simpa Salami, Bital Savir-Baruch, Sandy Srinivas and Thomas A. Hope

Journal of Nuclear Medicine September 30, 2021, jnumed.121.263262; DOI: https://doi.org/10.2967/jnumed.121.263262
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¹⁸F-FLT PET/CT as a prognostic imaging biomarker of disease specific survival in patients with primary soft tissue sarcoma
Joseph Crompton, Wesley R. Armstrong, Mark A. Eckardt, Ameen Seyedroudbari, William D. Tap, Sarah M. Dry, Evan R. Abt, Jeremie Calais, Ken Herrmann, Johannes Czernin, Fritz C. Eilber and Matthias R. Benz

Journal of Nuclear Medicine September 30, 2021, jnumed.121.262502; DOI: https://doi.org/10.2967/jnumed.121.262502
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Appropriate Use Criteria for the Use of Nuclear Medicine in Musculoskeletal Infection Imaging
Christopher Palestro, Alicia Clark, Erin Grady, Sherif Heiba, Ora Israel, Alan Klitzke, Charito Love, Mike Sathekge, S. Ted Treves and Tracy L. Yarbrough

Journal of Nuclear Medicine September 30, 2021, jnumed.121.262579; DOI: https://doi.org/10.2967/jnumed.121.262579
Open Access
Albumin Binder–Conjugated Fibroblast Activation Protein Inhibitor Radiopharmaceuticals for Cancer Therapy
Mengxin Xu, Pu Zhang, Jie Ding, Junyi Chen, Li Huo and Zhibo Liu

Journal of Nuclear Medicine September 30, 2021, jnumed.121.262533; DOI: https://doi.org/10.2967/jnumed.121.262533
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Predicting the outcome of epilepsy surgery by covariance pattern analysis of ictal perfusion SPECT
Jila Taherpour, Marian Jaber, Berthold Voges, Ivayla Apostolova, Thomas Sauvigny, Patrick M House, Michael Lanz, Matthias Lindenau, Susanne Klutmann, Tobias Martens, Stefan Stodieck and Ralph Buchert

Journal of Nuclear Medicine September 30, 2021, jnumed.121.262702; DOI: https://doi.org/10.2967/jnumed.121.262702

September 23, 2021

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Relationship between ¹⁸F-flortaucipir uptake and histologic lesion types in 4-repeat tauopathies
Keith Josephs, Nirubol Tosakulwong, Stephen Weigand, Marina Buciuc, Val lowe, Dennis Dickson and Jennifer Whitwell

Journal of Nuclear Medicine September 23, 2021, jnumed.121.262685; DOI: https://doi.org/10.2967/jnumed.121.262685
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Diagnostic performance of [¹²⁴I]m-iodobenzylguanidine PET/CT in patients with pheochromocytoma
Manuel Weber, Jochen Schmitz, Ines Maric, Kim Magaly Pabst, Lale Umutlu, Martin Walz, Ken Herrmann, Christoph Rischpler, Frank Weber, Walter Jentzen, Sarah Theurer, Thorsten D. Poeppel, Nicole Unger and Wolfgang P. Fendler

Journal of Nuclear Medicine September 23, 2021, jnumed.121.262797; DOI: https://doi.org/10.2967/jnumed.121.262797
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Radioembolization Versus Bland or Chemoembolization for Liver-Dominant Neuroendocrine Tumors: Is it an Either/Or Question?
Jonathan R. Strosberg, Ghassan El-Haddad, Taymeyah Al-Toubah, Diane Reidy, Etay Ziv, Armeen Mahvash, Arvind Dasari, Philip Philip and Michael C Soulen

Journal of Nuclear Medicine September 23, 2021, jnumed.121.263041; DOI: https://doi.org/10.2967/jnumed.121.263041
Open Access
Synthesis, preclinical evaluation, and a pilot clinical PET imaging study of ⁶⁸Ga-labeled FAPI dimer
Liang Zhao, Bo Niu, Jianyang Fang, Yizhen Pang, Siyang Li, Chengrong Xie, Long Sun, Xianzhong Zhang, Zhide Guo, Qin Lin and Haojun Chen

Journal of Nuclear Medicine September 23, 2021, jnumed.121.263016; DOI: https://doi.org/10.2967/jnumed.121.263016

September 16, 2021

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A VISION of ALSYMPCA
Paulo Schiavom Duarte

Journal of Nuclear Medicine September 16, 2021, jnumed.121.263160; DOI: https://doi.org/10.2967/jnumed.121.263160
Open Access
Synaptic vesicle glycoprotein 2A is affected in the CNS of Huntington’s Disease mice and post-mortem human HD brain
Daniele Bertoglio, Jeroen Verhaeghe, Leonie wyffels, Alan Miranda, Sigrid Stroobants, Ladislav Mrzljak, Celia Dominguez, Mette Skinbjerg, Jonathan Bard, Longbin Liu, Ignacio Munoz-Sanjuan and Steven Staelens

Journal of Nuclear Medicine September 16, 2021, jnumed.121.262709; DOI: https://doi.org/10.2967/jnumed.121.262709
Open Access
A guide to ComBat harmonization of imaging biomarkers in multicenter studies
Fanny Orlhac, Jakoba J Eertink, Anne-Segolene Cottereau, Josee M. Zijlstra, Catherine Thieblemont, Michel A. Meignan, Ronald Boellaard and Irene Buvat

Journal of Nuclear Medicine September 16, 2021, jnumed.121.262464; DOI: https://doi.org/10.2967/jnumed.121.262464
Open Access
Epidermal growth factor receptor targeted fluorescence molecular imaging for postoperative lymph node assessment in patients with oral cancer
Jasper Vonk, Jaron G de Wit, Floris J Voskuil, Yang Hang Tang, Wouter TR Hooghiemstra, Matthijs D Linssen, Evert van den Broek, Jan J Doff, Sebastiaan AHJ de Visscher, Kees P Schepman, Bert van der Vegt, Gooitzen M van Dam and Max JH Witjes

Journal of Nuclear Medicine September 16, 2021, jnumed.121.262530; DOI: https://doi.org/10.2967/jnumed.121.262530
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Feasibility of in vivo Imaging of Fibroblast Activation Protein in Human Arterial Walls
Meiqi Wu, Jing Ning, Jingle Li, Zhichao Lai, Ximin Shi, Haiqun Xing, Marcus Hacker, Bao Liu, Li Huo and Xiang Li

Journal of Nuclear Medicine September 16, 2021, jnumed.121.262863; DOI: https://doi.org/10.2967/jnumed.121.262863
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¹⁸F DCFPyL PET Acquisition, Interpretation and Reporting: Suggestions Post Food and Drug Administration Approval
Hong Song, Andrei Iagaru and Steven P. Rowe

Journal of Nuclear Medicine September 16, 2021, jnumed.121.262989; DOI: https://doi.org/10.2967/jnumed.121.262989
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Pre-therapeutic comparative dosimetry of ¹⁷⁷Lu-rhPSMA-7.3 and ¹⁷⁷Lu-PSMAI&T in patients with metastatic castration resistant prostate cancer (mCRPC)
Benedikt Feuerecker, Maythinee Chantadisai, Anne Allmann, Robert Tauber, Jakob Allmann, Lisa Steinhelfer, Isabel Rauscher, Alexander Wurzer, Hans-Jürgen Wester, Wolfgang Andreas Weber, Calogero D'Alessandria and Matthias Eiber

Journal of Nuclear Medicine September 16, 2021, jnumed.121.262671; DOI: https://doi.org/10.2967/jnumed.121.262671

September 9, 2021

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Glucagon Like Peptide-1 receptor imaging in individuals with Type 2 Diabetes
Olof Eriksson, Irina Velikyan, Torsten Haack, Martin Bossart, Iina Laitinen, Philip Just Larsen, Jan Erik Berglund, Gunnar Antoni, Lars Johansson, Stefan Pierrou, Joachim Tillner and Michael Wagner

Journal of Nuclear Medicine September 9, 2021, jnumed.121.262506; DOI: https://doi.org/10.2967/jnumed.121.262506

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