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Research ArticleCLINICAL INVESTIGATIONS

Reference Tissue Models and Blood–Brain Barrier Disruption: Lessons from (R)-[11C]PK11195 in Traumatic Brain Injury

Hedy Folkersma, Ronald Boellaard, W. Peter Vandertop, Reina W. Kloet, Mark Lubberink, Adriaan A. Lammertsma and Bart N.M. van Berckel
Journal of Nuclear Medicine December 2009, 50 (12) 1975-1979; DOI: https://doi.org/10.2967/jnumed.109.067512
Hedy Folkersma
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Ronald Boellaard
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W. Peter Vandertop
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Reina W. Kloet
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Mark Lubberink
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Adriaan A. Lammertsma
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Bart N.M. van Berckel
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Article Information

vol. 50 no. 12 1975-1979
DOI 
https://doi.org/10.2967/jnumed.109.067512
PubMed 
19910429

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication June 24, 2009
  • Accepted for publication August 20, 2009
  • Published online November 30, 2009.

Article Versions

  • previous version (November 12, 2009 - 05:39).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2009 by Society of Nuclear Medicine

Author Information

  1. Hedy Folkersma 1 ,
  2. Ronald Boellaard 2 ,
  3. W. Peter Vandertop 1 ,
  4. Reina W. Kloet 2 ,
  5. Mark Lubberink 2 ,
  6. Adriaan A. Lammertsma 2 and
  7. Bart N.M. van Berckel 2
  1. 1Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands; and 2Department of Nuclear Medicine and PET Research, VU University Medical Center, Amsterdam, The Netherlands
  1. For correspondence or reprints contact: Hedy Folkersma, Neurosurgical Center Amsterdam, VU University Medical Center, De Boelelaan 1117, NL-1081 HV, Amsterdam, The Netherlands. E-mail: hedy.folkersma{at}vumc.nl
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  • Increased cerebral (R)-[11C]PK11195 uptake and glutamate release in a rat model of traumatic brain injury: a longitudinal pilot study
    Hedy Folkersma, Jessica C Foster Dingley, Bart NM van Berckel, Annemieke Rozemuller, Ronald Boellaard, Marc C Huisman, Adriaan A Lammertsma, W Peter Vandertop, Carla FM Molthoff
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    Marloes H. J. Hagens, Sandeep S. V. Golla, Bieneke Janssen, Danielle J. Vugts, Wissam Beaino, Albert D. Windhorst, James O’Brien-Brown, Michael Kassiou, Robert C. Schuit, Lothar A. Schwarte, Helga E. de Vries, Joep Killestein, Frederik Barkhof, Bart N. M. van Berckel, Adriaan A. Lammertsma
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  • In vivo assessment of neuroinflammation in progressive multiple sclerosis: a proof of concept study with [18F]DPA714 PET
    Marloes H. J. Hagens, Sandeep V. Golla, Martijn T. Wijburg, Maqsood Yaqub, Dennis Heijtel, Martijn D. Steenwijk, Patrick Schober, John J. P. Brevé, Robert C. Schuit, Tristan A. Reekie, Michael Kassiou, Anne-Marie van Dam, Albert D. Windhorst, Joep Killestein, Frederik Barkhof, Bart N. M. van Berckel, Adriaan A. Lammertsma
    Journal of Neuroinflammation 2018 15 1
  • Quantitative positron emission tomography in brain research
    Kerstin Heurling, Antoine Leuzy, My Jonasson, Andreas Frick, Eduardo R. Zimmer, Agneta Nordberg, Mark Lubberink
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Journal of Nuclear Medicine: 50 (12)
Journal of Nuclear Medicine
Vol. 50, Issue 12
December 2009
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Reference Tissue Models and Blood–Brain Barrier Disruption: Lessons from (R)-[11C]PK11195 in Traumatic Brain Injury
Hedy Folkersma, Ronald Boellaard, W. Peter Vandertop, Reina W. Kloet, Mark Lubberink, Adriaan A. Lammertsma, Bart N.M. van Berckel
Journal of Nuclear Medicine Dec 2009, 50 (12) 1975-1979; DOI: 10.2967/jnumed.109.067512

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Reference Tissue Models and Blood–Brain Barrier Disruption: Lessons from (R)-[11C]PK11195 in Traumatic Brain Injury
Hedy Folkersma, Ronald Boellaard, W. Peter Vandertop, Reina W. Kloet, Mark Lubberink, Adriaan A. Lammertsma, Bart N.M. van Berckel
Journal of Nuclear Medicine Dec 2009, 50 (12) 1975-1979; DOI: 10.2967/jnumed.109.067512
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Cited By...

  • Serial Quantitative TSPO-Targeted PET Reveals Peak Microglial Activation up to 2 Weeks After an Epileptogenic Brain Insult
  • Widespread and Prolonged Increase in (R)-11C-PK11195 Binding After Traumatic Brain Injury
  • Google Scholar

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