Both ventilation–perfusion SPECT and multidetector CT angiography have high accuracy in the diagnosis of pulmonary embolism, but only limited data comparing the two are available. A prospective study using a hybrid scanner has concluded that ventilation–perfusion SPECT in combination with unenhanced low-dose CT has excellent diagnostic performance and should probably be considered first-line imaging in the work-up of most cases of pulmonary embolism.
See page 1987.