Journal of Nuclear Medicine: 64 (10)

October 1, 2023; Volume 64,Issue 10

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine October 1, 2023, 64 (10) 10A;

Editor’s Page

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A Tribute to Our JNM Associate Editors
Johannes Czernin

Journal of Nuclear Medicine October 1, 2023, 64 (10) 1505; DOI: https://doi.org/10.2967/jnumed.123.266620

Discussions with Leaders

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Pioneering Research on Cancer Quality of Life and Outcomes
Patricia A. Ganz and Johannes Czernin

Journal of Nuclear Medicine October 1, 2023, 64 (10) 1506-1508; DOI: https://doi.org/10.2967/jnumed.123.266602

State of the Art

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Ethical Considerations for Artificial Intelligence in Medical Imaging: Deployment and Governance
Jonathan Herington, Melissa D. McCradden, Kathleen Creel, Ronald Boellaard, Elizabeth C. Jones, Abhinav K. Jha, Arman Rahmim, Peter J.H. Scott, John J. Sunderland, Richard L. Wahl, Sven Zuehlsdorff and Babak Saboury

Journal of Nuclear Medicine October 1, 2023, 64 (10) 1509-1515; DOI: https://doi.org/10.2967/jnumed.123.266110

Editorial

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Is Actinium Really Happening?
Richard Zimmermann

Journal of Nuclear Medicine October 1, 2023, 64 (10) 1516-1518; DOI: https://doi.org/10.2967/jnumed.123.265907

Oncology

Clinical
- Open Access
  Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH–Wild-Type Glioblastoma
  Nathalie L. Albert, Debie V. Nelwan, Daniel F. Fleischmann, Stefanie Quach, Katharina von Rohr, Lena Kaiser, Nico Teske, Lena M. Unterrainer, Laura M. Bartos, Viktoria C. Ruf, Matthias Brendel, Markus J. Riemenschneider, Christian Wetzel, Jochen Herms, Rainer Rupprecht, Niklas Thon, Joerg-Christian Tonn, Claus Belka, Peter Bartenstein, Louisa von Baumgarten, Maximilian Niyazi, Marcus Unterrainer and Adrien Holzgreve
  
  Journal of Nuclear Medicine October 1, 2023, 64 (10) 1519-1525; DOI: https://doi.org/10.2967/jnumed.122.265247
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  PET Imaging and Protein Expression of Prostate-Specific Membrane Antigen in Glioblastoma: A Multicenter Inventory Study
  Sanne A.M. van Lith, Ilanah J. Pruis, Nelleke Tolboom, Tom J. Snijders, Dylan Henssen, Mark ter Laan, Maarten te Dorsthorst, William P.J. Leenders, Martin Gotthardt, James Nagarajah, Pierre A. Robe, Philip De Witt Hamer, Harry Hendrikse, Daniela E. Oprea-Lager, Maqsood Yaqub, Ronald Boellaard, Pieter Wesseling, Rutger K. Balvers, Frederik A. Verburg, Anita A. Harteveld, Marion Smits, Martin van den Bent, Sophie E.M. Veldhuijzen van Zanten and Elsmarieke van de Giessen
  
  Journal of Nuclear Medicine October 1, 2023, 64 (10) 1526-1531; DOI: https://doi.org/10.2967/jnumed.123.265738
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  Comparison of Baseline ⁶⁸Ga-FAPI and ¹⁸F-FDG PET/CT for Prediction of Response and Clinical Outcome in Patients with Unresectable Hepatocellular Carcinoma Treated with PD-1 Inhibitor and Lenvatinib
  Meiqi Wu, Yanyu Wang, Qiao Yang, Xuezhu Wang, Xu Yang, Haiqun Xing, Xinting Sang, Xiang Li, Haitao Zhao and Li Huo
  
  Journal of Nuclear Medicine October 1, 2023, 64 (10) 1532-1539; DOI: https://doi.org/10.2967/jnumed.123.265712
- FEATURED ARTICLE OF THE MONTH
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    ⁶⁸Ga-SSO-120 PET for Initial Staging of Small Cell Lung Cancer Patients: A Single-Center Retrospective Study
    David Kersting, Patrick Sandach, Miriam Sraieb, Marcel Wiesweg, Martin Metzenmacher, Kaid Darwiche, Filiz Oezkan, Servet Bölükbas, Martin Stuschke, Lale Umutlu, Michael Nader, Rainer Hamacher, Wolfgang P. Fendler, Johannes Wienker, Wilfried E.E. Eberhardt, Martin Schuler, Ken Herrmann and Hubertus Hautzel
    
    Journal of Nuclear Medicine October 1, 2023, 64 (10) 1540-1549; DOI: https://doi.org/10.2967/jnumed.123.265664
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  The Association Between [⁶⁸Ga]PSMA PET/CT Response and Biochemical Progression in Patients with High-Risk Prostate Cancer Receiving Neoadjuvant Therapy
  Mengxia Chen, Yao Fu, Shan Peng, Shiming Zang, Shuyue Ai, Junlong Zhuang, Feng Wang, Xuefeng Qiu and Hongqian Guo
  
  Journal of Nuclear Medicine October 1, 2023, 64 (10) 1550-1555; DOI: https://doi.org/10.2967/jnumed.122.265368
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  ⁶⁸Ga-PSMA PET/CT for Response Evaluation of ²²³Ra Treatment in Metastatic Prostate Cancer
  Anouk C. de Jong, Marcel Segbers, Sui Wai Ling, Laura H. Graven, Niven Mehra, Paul Hamberg, Tessa Brabander, Ronald de Wit and Astrid A.M. van der Veldt
  
  Journal of Nuclear Medicine October 1, 2023, 64 (10) 1556-1562; DOI: https://doi.org/10.2967/jnumed.123.265489
- BRIEF COMMUNICATION
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    The Diagnostic Value of the Sentinel Node Procedure to Detect Occult Lymph Node Metastases in PSMA PET/CT Node–Negative Prostate Cancer Patients
    Jan J. Duin, Hilda A. de Barros, Maarten L. Donswijk, Eva E. Schaake, Tim M. van der Sluis, Esther M.K. Wit, Fijs W.B. van Leeuwen, Pim J. van Leeuwen and Henk G. van der Poel
    
    Journal of Nuclear Medicine October 1, 2023, 64 (10) 1563-1566; DOI: https://doi.org/10.2967/jnumed.123.265556

Theranostics

Clinical
- BRIEF COMMUNICATION
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    Radiation Safety Considerations of Household Waste Disposal After Release of Patients Who Have Received [¹⁷⁷Lu]Lu-PSMA-617
    Stephen A. Graves
    
    Journal of Nuclear Medicine October 1, 2023, 64 (10) 1567-1569; DOI: https://doi.org/10.2967/jnumed.123.265750
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    [¹⁷⁷Lu]Lu-PSMA-617 Therapy in a Patient with Chronic Kidney Disease
    Lorenzo Mercolli, Clemens Mingels, Giulia Manzini, Paul Cumming, Konstantinos Zeimpekis, Song Xue, Ian Alberts, Dominik Uehlinger, Axel Rominger, Kuangyu Shi and Ali Afshar-Oromieh
    
    Journal of Nuclear Medicine October 1, 2023, 64 (10) 1570-1573; DOI: https://doi.org/10.2967/jnumed.123.265577
- $Clinical Experience with [<sup>225</sup>Ac]Ac-PSMA Treatment in Patients with [<sup>177</sup>Lu]Lu-PSMA–Refractory Metastatic Castration-Resistant Prostate Cancer$
  
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  Clinical Experience with [²²⁵Ac]Ac-PSMA Treatment in Patients with [¹⁷⁷Lu]Lu-PSMA–Refractory Metastatic Castration-Resistant Prostate Cancer
  Nalan Alan-Selcuk, Gamze Beydagi, Emre Demirci, Meltem Ocak, Serkan Celik, Bala B. Oven, Turkay Toklu, Ipek Karaaslan, Kaan Akcay, Omer Sonmez and Levent Kabasakal
  
  Journal of Nuclear Medicine October 1, 2023, 64 (10) 1574-1580; DOI: https://doi.org/10.2967/jnumed.123.265546

Neurology

Basic
- Open Access
  In Vivo Cerebral Imaging of Mutant Huntingtin Aggregates Using ¹¹C-CHDI-180R PET in a Nonhuman Primate Model of Huntington Disease
  Daniele Bertoglio, Alison R. Weiss, William Liguore, Lauren Drew Martin, Theodore Hobbs, John Templon, Sathya Srinivasan, Celia Dominguez, Ignacio Munoz-Sanjuan, Vinod Khetarpal, Jeroen Verhaeghe, Steven Staelens, Jeanne Link, Longbin Liu, Jonathan A. Bard and Jodi L. McBride
  
  Journal of Nuclear Medicine October 1, 2023, 64 (10) 1581-1587; DOI: https://doi.org/10.2967/jnumed.123.265569
- Open Access
  Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain
  Brendon E. Cook, Sangram Nag, Ryosuke Arakawa, Edward Yin-Shiang Lin, Nancy Stratman, Kevin Guckian, Heike Hering, Mukesh Lulla, Jinkuk Choi, Cristian Salinas, Nathan E. Genung, Anton Forsberg Morén, Martin Bolin, Giulia Boscutti, Christophe Plisson, Laurent Martarello, Christer Halldin and Maciej A. Kaliszczak
  
  Journal of Nuclear Medicine October 1, 2023, 64 (10) 1588-1593; DOI: https://doi.org/10.2967/jnumed.122.265225

AI/Advanced Image Analysis

Clinical
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  Automated Brain Tumor Detection and Segmentation for Treatment Response Assessment Using Amino Acid PET
  Robin Gutsche, Carsten Lowis, Karl Ziemons, Martin Kocher, Garry Ceccon, Cláudia Régio Brambilla, Nadim J. Shah, Karl-Josef Langen, Norbert Galldiks, Fabian Isensee and Philipp Lohmann
  
  Journal of Nuclear Medicine October 1, 2023, 64 (10) 1594-1602; DOI: https://doi.org/10.2967/jnumed.123.265725
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  Stacking Ensemble Learning–Based [¹⁸F]FDG PET Radiomics for Outcome Prediction in Diffuse Large B-Cell Lymphoma
  Shuilin Zhao, Jing Wang, Chentao Jin, Xiang Zhang, Chenxi Xue, Rui Zhou, Yan Zhong, Yuwei Liu, Xuexin He, Youyou Zhou, Caiyun Xu, Lixia Zhang, Wenbin Qian, Hong Zhang, Xiaohui Zhang and Mei Tian
  
  Journal of Nuclear Medicine October 1, 2023, 64 (10) 1603-1609; DOI: https://doi.org/10.2967/jnumed.122.265244

Radiobiology/Dosimetry

Clinical
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  Impact of Single-Time-Point Estimates of ¹⁷⁷Lu-PRRT Absorbed Doses on Patient Management: Validation of a Trained Multiple-Linear-Regression Model in 159 Patients and 477 Therapy Cycles
  Alexandre Chicheportiche, Moshe Sason, Mahmoud Zidan, Jeremy Godefroy, Yodphat Krausz, David J. Gross, Simona Grozinsky-Glasberg and Simona Ben-Haim
  
  Journal of Nuclear Medicine October 1, 2023, 64 (10) 1610-1616; DOI: https://doi.org/10.2967/jnumed.122.264923
- INVITED PERSPECTIVE
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    Choosing the Right Metrics for Evaluation of Radiopharmaceutical Therapy Dosimetry Methodologies
    Joshua S. Scheuermann and Daniel A. Pryma
    
    Journal of Nuclear Medicine October 1, 2023, 64 (10) 1617-1618; DOI: https://doi.org/10.2967/jnumed.123.266304
Basic
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  Membrane and Nuclear Absorbed Doses from ¹⁷⁷Lu and ¹⁶¹Tb in Tumor Clusters: Effect of Cellular Heterogeneity and Potential Benefit of Dual Targeting—A Monte Carlo Study
  Alexandre Larouze, Mario Alcocer-Ávila, Clément Morgat, Christophe Champion and Elif Hindié
  
  Journal of Nuclear Medicine October 1, 2023, 64 (10) 1619-1624; DOI: https://doi.org/10.2967/jnumed.123.265509
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  Albumin-Binding and Conventional PSMA Ligands in Combination with ¹⁶¹Tb: Biodistribution, Dosimetry, and Preclinical Therapy
  Viviane J. Tschan, Sarah D. Busslinger, Peter Bernhardt, Pascal V. Grundler, Jan Rijn Zeevaart, Ulli Köster, Nicholas P. van der Meulen, Roger Schibli and Cristina Müller
  
  Journal of Nuclear Medicine October 1, 2023, 64 (10) 1625-1631; DOI: https://doi.org/10.2967/jnumed.123.265524
- Open Access
  Tumor Control Probability and Small-Scale Monte Carlo Dosimetry: Effects of Heterogenous Intratumoral Activity Distribution in Radiopharmaceutical Therapy
  Emma Mellhammar, Magnus Dahlbom, Oskar Vilhelmsson-Timmermand and Sven-Erik Strand
  
  Journal of Nuclear Medicine October 1, 2023, 64 (10) 1632-1637; DOI: https://doi.org/10.2967/jnumed.123.265523

Molecular Imaging

Basic
- FEATURED BASIC ARTICLE OF THE MONTH
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    Immuno-PET Detects Antibody–Drug Potency on Coadministration with Statins
    Emma L. Brown, Shayla Shmuel, Komal Mandleywala, Sandeep Surendra Panikar, Na-Keysha Berry, Yi Rao, Abbey Zidel, Jason S. Lewis and Patrícia M.R. Pereira
    
    Journal of Nuclear Medicine October 1, 2023, 64 (10) 1638-1646; DOI: https://doi.org/10.2967/jnumed.122.265172
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  Ambient Light Resistant Shortwave Infrared Fluorescence Imaging for Preclinical Tumor Delineation via the pH Low-Insertion Peptide Conjugated to Indocyanine Green
  Benedict Edward Mc Larney, Mijin Kim, Sheryl Roberts, Magdalena Skubal, Hsiao-Ting Hsu, Anuja Ogirala, Edwin C. Pratt, Naga Vara Kishore Pillarsetty, Daniel A. Heller, Jason S. Lewis and Jan Grimm
  
  Journal of Nuclear Medicine October 1, 2023, 64 (10) 1647-1653; DOI: https://doi.org/10.2967/jnumed.123.265686
- Open Access
  Preclinical Comparison of the ⁶⁴Cu- and ⁶⁸Ga-Labeled GRPR-Targeted Compounds RM2 and AMTG, as Well as First-in-Humans [⁶⁸Ga]Ga-AMTG PET/CT
  Lena Koller, Markus Joksch, Sarah Schwarzenböck, Jens Kurth, Martin Heuschkel, Nadine Holzleitner, Roswitha Beck, Gunhild von Amsberg, Hans-Jürgen Wester, Bernd Joachim Krause and Thomas Günther
  
  Journal of Nuclear Medicine October 1, 2023, 64 (10) 1654-1659; DOI: https://doi.org/10.2967/jnumed.123.265771

Illustrated Post

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[⁶⁸Ga]Ga-FAPI-46 PET for Visualization of Postinfarction Renal Fibrosis
Lena M. Unterrainer, Anthony E. Sisk, Johannes Czernin, Brian M. Shuch, Jeremie Calais and Masatoshi Hotta

Journal of Nuclear Medicine October 1, 2023, 64 (10) 1660-1661; DOI: https://doi.org/10.2967/jnumed.123.265640

Letters to the Editor

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Not All Gatekeepers Are Theranostics
Dale L. Bailey

Journal of Nuclear Medicine October 1, 2023, 64 (10) 1662; DOI: https://doi.org/10.2967/jnumed.123.266006
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Reply to: Not All Gatekeepers Are Theranostics
Wolfgang Andreas Weber, Henryk Barthel, Frank M. Bengel, Matthias M. Eiber, Ken Herrmann and Michael Schäfers

Journal of Nuclear Medicine October 1, 2023, 64 (10) 1662-1663; DOI: https://doi.org/10.2967/jnumed.123.266028
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Potential of ¹⁸⁸Re as an Alternative to ¹⁷⁷Lu and Dosimetric Consequences
Marc Pretze, Jörg Kotzerke, Robert Freudenberg and Claudia Brogsitter

Journal of Nuclear Medicine October 1, 2023, 64 (10) 1663; DOI: https://doi.org/10.2967/jnumed.123.265782
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Reply to: Potential of ¹⁸⁸Re as an Alternative to ¹⁷⁷Lu and Dosimetric Consequences
Jens Cardinale, Frederik L. Giesel, Christina Wensky, Hendrik G. Rathke, Uwe Haberkorn and Clemens Kratochwil

Journal of Nuclear Medicine October 1, 2023, 64 (10) 1663-1664; DOI: https://doi.org/10.2967/jnumed.123.266195
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Response to “Critique and Discussion of ‘Multicenter Evaluation of Frequency and Impact of Activity Infiltration in PET Imaging, Including Microscale Modeling of Skin-Absorbed Dose’”
John J. Sunderland, Stephen A. Graves, Dusty M. York, Christine A. Mundt and Twyla B. Bartel

Journal of Nuclear Medicine October 1, 2023, 64 (10) 1664-1667; DOI: https://doi.org/10.2967/jnumed.123.266596

Addendum

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Addendum to MIRD Pamphlet No. 28
Adam L. Kesner, Lukas M. Carter and Wesley E. Bolch

Journal of Nuclear Medicine October 1, 2023, 64 (10) 1668; DOI: https://doi.org/10.2967/jnumed.123.266325

In Memoriam

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Johan S. Masjhur, dr, SpPD-KEMD, SpKN-TM, 1942–2023
Hussein S. Kartamihardja and Dale L. Bailey

Journal of Nuclear Medicine October 1, 2023, 64 (10) 1669; DOI: https://doi.org/10.2967/jnumed.123.266196

Departments

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Erratum
Journal of Nuclear Medicine October 1, 2023, 64 (10) 1668;

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Table of Contents

This Month in JNM

Editor’s Page

Discussions with Leaders

State of the Art

Editorial

Oncology

Clinical

FEATURED ARTICLE OF THE MONTH

BRIEF COMMUNICATION

Theranostics

Clinical

BRIEF COMMUNICATION

Neurology

Basic

AI/Advanced Image Analysis

Clinical

Radiobiology/Dosimetry

Clinical

INVITED PERSPECTIVE

Basic

Molecular Imaging

Basic

FEATURED BASIC ARTICLE OF THE MONTH

Illustrated Post

Letters to the Editor

Addendum

In Memoriam

Departments

In this issue

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