Table of Contents

September 1, 2023; Volume 64,Issue 9

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine September 1, 2023, 64 (9) 8A;

Editor’s Page

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The Future of Nuclear Medicine
David Mankoff

Journal of Nuclear Medicine September 1, 2023, 64 (9) 1329-1330; DOI: https://doi.org/10.2967/jnumed.123.266448

Continuing Education

Open Access
New Developments in Myeloma Treatment and Response Assessment
Françoise Kraeber-Bodéré, Bastien Jamet, Davide Bezzi, Elena Zamagni, Philippe Moreau and Cristina Nanni

Journal of Nuclear Medicine September 1, 2023, 64 (9) 1331-1343; DOI: https://doi.org/10.2967/jnumed.122.264972

Focus on Molecular Imaging

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Marshalling the Potential of Auger Electron Radiopharmaceutical Therapy
Julie Bolcaen, Mohamed A. Gizawy, Samantha Y.A. Terry, António Paulo, Bart Cornelissen, Aruna Korde, Jonathan Engle, Valery Radchenko and Roger W. Howell

Journal of Nuclear Medicine September 1, 2023, 64 (9) 1344-1351; DOI: https://doi.org/10.2967/jnumed.122.265039

Issues and Controversies

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The Future of Nuclear Medicine in the United States
Michael M. Graham

Journal of Nuclear Medicine September 1, 2023, 64 (9) 1352-1353; DOI: https://doi.org/10.2967/jnumed.122.265314
INVITED PERSPECTIVE
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  The Future of Nuclear Medicine in the United States
  George M. Segall, Maria Watts and Kirk A. Frey
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1354-1355; DOI: https://doi.org/10.2967/jnumed.123.265674
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  Stronger Together—Collaboration Will Only Enhance Patient Care
  Erin E. Grady, David A. Mankoff and David M. Schuster
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1356-1358; DOI: https://doi.org/10.2967/jnumed.123.265673
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  Redesigned Curricula, Stringent Licensing Criteria, and Integrated Independence Are Conditions for a Bright Future for Nuclear Medicine in the United States
  Johannes Czernin and Jeremie Calais
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1359-1360; DOI: https://doi.org/10.2967/jnumed.123.265672

Discussions with Leaders

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Toward Integrated Independence
Ebrahim S. Delpassand, Eric M. Rohren, Wolfgang A. Weber and Johannes Czernin

Journal of Nuclear Medicine September 1, 2023, 64 (9) 1361-1363; DOI: https://doi.org/10.2967/jnumed.123.266395

Oncology

Clinical
- FEATURED ARTICLE OF THE MONTH
  - Open Access
    Human Epidermal Growth Factor Receptor 2–Targeting [⁶⁸Ga]Ga-ABY-025 PET/CT Predicts Early Metabolic Response in Metastatic Breast Cancer
    Ali Alhuseinalkhudhur, Henrik Lindman, Per Liss, Tora Sundin, Fredrik Y. Frejd, Johan Hartman, Victor Iyer, Joachim Feldwisch, Mark Lubberink, Caroline Rönnlund, Vladimir Tolmachev, Irina Velikyan and Jens Sörensen
    
    Journal of Nuclear Medicine September 1, 2023, 64 (9) 1364-1370; DOI: https://doi.org/10.2967/jnumed.122.265364
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  [¹⁸F]FDG PET/CT in the Initial Staging and Restaging of Soft-Tissue or Bone Sarcoma in Patients with Negative or Equivocal Findings for Metastases or Limited Recurrence on Conventional Work-up: Results of a Prospective Multicenter Registry
  Ur Metser, Roshini Kulanthaivelu, Abdulazeez Salawu, Albiruni Razak, Victor Mak, Xuan Li, Deanna L. Langer, Pamela MacCrostie and Amit Singunkar
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1371-1377; DOI: https://doi.org/10.2967/jnumed.122.265278
- Open Access
  Phase I Study of [⁶⁸Ga]Ga-Anti-CD206-sdAb for PET/CT Assessment of Protumorigenic Macrophage Presence in Solid Tumors (MMR Phase I)
  Odrade Gondry, Catarina Xavier, Laurens Raes, Johannes Heemskerk, Nick Devoogdt, Hendrik Everaert, Karine Breckpot, Quentin Lecocq, Lore Decoster, Christel Fontaine, Denis Schallier, Sandrine Aspeslagh, Ilse Vaneycken, Geert Raes, Jo A. Van Ginderachter, Tony Lahoutte, Vicky Caveliers and Marleen Keyaerts
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1378-1384; DOI: https://doi.org/10.2967/jnumed.122.264853
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  Performance of ⁶⁸Ga-Labeled Fibroblast Activation Protein Inhibitor PET/CT in Evaluation of Erdheim–Chester Disease: A Comparison with ¹⁸F-FDG PET/CT
  Jiangyu Ma, Qiao Yang, Li Huo, Jiawen Dai, Na Niu and Xinxin Cao
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1385-1391; DOI: https://doi.org/10.2967/jnumed.123.265691
- Open Access
  Pain Outcomes in Patients with Metastatic Castration-Resistant Prostate Cancer Treated with ²²³Ra: PARABO, a Prospective, Noninterventional Study
  Holger Palmedo, Hojjat Ahmadzadehfar, Susanne Eschmann, Andreas Niesen, Johann Schönberger, Vahé Barsegian, Knut Liepe, Felix M. Mottaghy, Rongjin Guan, Joerg Pinkert, Per Sandström and Ken Herrmann
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1392-1398; DOI: https://doi.org/10.2967/jnumed.123.265557

Theranostics

Clinical
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  Fibroblast Activation Protein and Glycolysis in Lymphoma Diagnosis: Comparison of ⁶⁸Ga-FAPI PET/CT and ¹⁸F-FDG PET/CT
  Xuetao Chen, Shuailiang Wang, Yumei Lai, Guochang Wang, Maomao Wei, Xiao Jin, Jin Ding, Yan Zhang, Yunfei Shi, Feng Wang, Hua Zhu, Zhi Yang and Xuejuan Wang
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1399-1405; DOI: https://doi.org/10.2967/jnumed.123.265530
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  Head-to-Head Comparison of ⁶⁸Ga-NODAGA-JR11 and ⁶⁸Ga-DOTATATE PET/CT in Patients with Metastatic, Well-Differentiated Neuroendocrine Tumors: Interim Analysis of a Prospective Bicenter Study
  Zefang Lin, Wenjia Zhu, Jiaying Zhang, Weibing Miao, Shaobo Yao and Li Huo
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1406-1411; DOI: https://doi.org/10.2967/jnumed.122.264890
- BRIEF COMMUNICATION
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    The Tyr Phenomenon: A Hypocalcemic Response in High-Volume Treatment Responders to ¹⁷⁷Lu-Prostate-Specific Membrane Antigen Therapy
    Shejil Kumar, Megan Crumbaker, Christopher Harvey, Sarennya Pathmanandavel, Nikieth John, Mina M. Swiha, Michelle M. McDonald, Roderick Clifton-Bligh, Adrian Lee, Patricia Bastick, William Counter, Andrew Nguyen and Louise Emmett
    
    Journal of Nuclear Medicine September 1, 2023, 64 (9) 1412-1416; DOI: https://doi.org/10.2967/jnumed.123.265759
- PRACTICE STANDARDS
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    SNMMI Consensus Statement on Patient Selection and Appropriate Use of ¹⁷⁷Lu-PSMA-617 Radionuclide Therapy
    Thomas A. Hope, Emmanuel S. Antonarakis, Lisa Bodei, Jeremie Calais, Amir Iravani, Heather Jacene, Phillip J. Koo, Alicia K. Morgans, Joseph R. Osborne, Scott T. Tagawa, Mary-Ellen Taplin, Oliver Sartor and Michael J. Morris
    
    Journal of Nuclear Medicine September 1, 2023, 64 (9) 1417-1423; DOI: https://doi.org/10.2967/jnumed.123.265952
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  CXCR4-Directed Imaging and Endoradiotherapy in Desmoplastic Small Round Cell Tumors
  Ingo Hartlapp, Philipp E. Hartrampf, Sebastian E. Serfling, Vanessa Wild, Alexander Weich, Leo Rasche, Sabine Roth, Andreas Rosenwald, Patrick W. Mihatsch, Anne Hendricks, Armin Wiegering, Verena Wiegering, Heribert Hänscheid, Andreas Schirbel, Rudolf A. Werner, Andreas K. Buck, Hans-Jürgen Wester, Hermann Einsele, Volker Kunzmann, Constantin Lapa and K. Martin Kortüm
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1424-1430; DOI: https://doi.org/10.2967/jnumed.123.265464
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  Dual-Time-Point Posttherapy ¹⁷⁷Lu-PSMA-617 SPECT/CT Describes the Uptake Kinetics of mCRPC Lesions and Prognosticates Patients’ Outcome
  Manuela Straub, Jürgen Kupferschläger, Lina Maria Serna Higuita, Matthias Weissinger, Helmut Dittmann, Christian la Fougère and Francesco Fiz
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1431-1438; DOI: https://doi.org/10.2967/jnumed.122.264770
Basic
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  Efficacy of HER2-Targeted Intraperitoneal ²²⁵Ac α-Pretargeted Radioimmunotherapy for Small-Volume Ovarian Peritoneal Carcinomatosis
  Sebastian K. Chung, Daniela Burnes Vargas, Christopher S. Chandler, Sumudu Katugampola, Darren R. Veach, Michael R. McDevitt, Shin H. Seo, Brett A. Vaughn, Sara S. Rinne, Blesida Punzalan, Mitesh Patel, Hong Xu, Hong-Fen Guo, Pat B. Zanzonico, Sébastien Monette, Guangbin Yang, Ouathek Ouerfelli, Garrett M. Nash, Andrea Cercek, Edward K. Fung, Roger W. Howell, Steven M. Larson, Sarah M. Cheal and Nai-Kong V. Cheung
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1439-1445; DOI: https://doi.org/10.2967/jnumed.122.265095
- INVITED PERSPECTIVE
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    Pretargeted Radioimmunotherapy of Ovarian Cancer with ²²⁵Ac and an Internalizing Antibody
    Xiaoyan Li, Xiaoli Lan and Weibo Cai
    
    Journal of Nuclear Medicine September 1, 2023, 64 (9) 1446-1448; DOI: https://doi.org/10.2967/jnumed.123.266026
- Open Access
  Development of FAPI Tetramers to Improve Tumor Uptake and Efficacy of FAPI Radioligand Therapy
  Yizhen Pang, Liang Zhao, Jianyang Fang, Jianhao Chen, Lingxin Meng, Long Sun, Hua Wu, Zhide Guo, Qin Lin and Haojun Chen
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1449-1455; DOI: https://doi.org/10.2967/jnumed.123.265599

Radiobiology/Dosimetry

Clinical
- Open Access
  Specific Uptake in the Bone Marrow Causes High Absorbed Red Marrow Doses During [¹⁷⁷Lu]Lu-DOTATATE Treatment
  Jens Hemmingsson, Johanna Svensson, Andreas Hallqvist, Katja Smits, Viktor Johanson and Peter Bernhardt
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1456-1462; DOI: https://doi.org/10.2967/jnumed.123.265484
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  Single-Time-Point Imaging for Dosimetry After [¹⁷⁷Lu]Lu-DOTATATE: Accuracy of Existing Methods and Novel Data-Driven Models for Reducing Sensitivity to Time-Point Selection
  Chang Wang, Avery B. Peterson, Ka Kit Wong, Molly E. Roseland, Matthew J. Schipper and Yuni K. Dewaraja
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1463-1470; DOI: https://doi.org/10.2967/jnumed.122.265338
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  Monte Carlo Simulations Corroborate PET-Measured Discrepancies in Activity Assessments of Commercial ⁹⁰Y Vials
  Lucrezia Auditore, Daniele Pistone, Antonio Italiano, Ernesto Amato and Silvano Gnesin
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1471-1477; DOI: https://doi.org/10.2967/jnumed.123.265494

Cardiovascular

Clinical
- Open Access
  Temporal Changes in Coronary ¹⁸F-Fluoride Plaque Uptake in Patients with Coronary Atherosclerosis
  Marwa Daghem, Philip D. Adamson, Kang-Ling Wang, Mhairi Doris, Rong Bing, Edwin J.R. van Beek, Laura Forsyth, Michelle C. Williams, Evangelos Tzolos, Damini Dey, Piotr J. Slomka, Marc R. Dweck, David E. Newby and Alastair J. Moss
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1478-1486; DOI: https://doi.org/10.2967/jnumed.122.264331
Basic
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  Multimodality Imaging of Aortic Valve Calcification and Function in a Murine Model of Calcific Aortic Valve Disease and Bicuspid Aortic Valve
  Azmi A. Ahmad, Mean Ghim, Jakub Toczek, Afarin Neishabouri, Devi Ojha, Zhengxing Zhang, Kiran Gona, Muhammad Zawwad Raza, Jae-Joon Jung, Gunjan Kukreja, Jiasheng Zhang, Nicole Guerrera, Chi Liu and Mehran M. Sadeghi
  
  Journal of Nuclear Medicine September 1, 2023, 64 (9) 1487-1494; DOI: https://doi.org/10.2967/jnumed.123.265516

Neurology

Basic
- FEATURED BASIC SCIENCE ARTICLE
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    Preclinical Characterization of the Tau PET Tracer [¹⁸F]SNFT-1: Comparison of Tau PET Tracers
    Ryuichi Harada, Pradith Lerdsirisuk, Yuki Shimizu, Yuka Yokoyama, Yiqing Du, Kaede Kudo, Michinori Ezura, Yoichi Ishikawa, Ren Iwata, Miho Shidahara, Aiko Ishiki, Akio Kikuchi, Yuya Hatano, Tomohiko Ishihara, Osamu Onodera, Yasushi Iwasaki, Mari Yoshida, Yasuyuki Taki, Hiroyuki Arai, Yukitsuka Kudo, Kazuhiko Yanai, Shozo Furumoto and Nobuyuki Okamura
    
    Journal of Nuclear Medicine September 1, 2023, 64 (9) 1495-1501; DOI: https://doi.org/10.2967/jnumed.123.265593

Illustrated Post

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PSMA-Negative Lesion Progression Under ¹⁷⁷Lu-PSMA Radioligand Therapy
Vishnu Murthy, Martin Allen-Auerbach, Richard Lam, Dawn Owen, Johannes Czernin and Jeremie Calais

Journal of Nuclear Medicine September 1, 2023, 64 (9) 1502-1503; DOI: https://doi.org/10.2967/jnumed.122.265099

Departments

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Erratum
Journal of Nuclear Medicine September 1, 2023, 64 (9) 1503;