Table of Contents

November 1, 2023; Volume 64,Issue 11

This Month in JNM

You have access
This Month in JNM
Journal of Nuclear Medicine November 1, 2023, 64 (11) 10A;

Discussions with Leaders

You have access
Advancing Nuclear Medicine at the Multiomics Intersection
Kalevi Kairemo and Johannes Czernin

Journal of Nuclear Medicine November 1, 2023, 64 (11) 1671-1673; DOI: https://doi.org/10.2967/jnumed.123.266793

Hot Topics

You have access
FAPI PET/CT Immune-Fibrosis Imaging for New Insights into Rheumatologic Disorders
Christian Schmidkonz, Armin Atzinger, Andreas Ramming and Torsten Kuwert

Journal of Nuclear Medicine November 1, 2023, 64 (11) 1674-1675; DOI: https://doi.org/10.2967/jnumed.123.266182

Focus on Molecular Imaging

You have access
The Development and Validation of Radiopharmaceuticals Targeting Bacterial Infection
Signore Alberto, Alvaro A. Ordonez, Chanda Arjun, Gurpreet Kaur Aulakh, Nicolas Beziere, Ekaterina Dadachova, Thomas Ebenhan, Ulises Granados, Aruna Korde, Amirreza Jalilian, Wening Lestari, Archana Mukherjee, Milos Petrik, Tamer Sakr, Clara L. Santos Cuevas, Mick M. Welling, Jan Rijn Zeevaart, Sanjay K. Jain and David M. Wilson

Journal of Nuclear Medicine November 1, 2023, 64 (11) 1676-1682; DOI: https://doi.org/10.2967/jnumed.123.265906

Oncology

Clinical
- Open Access
  Predictive IDH Genotyping Based on the Evaluation of Spatial Metabolic Heterogeneity by Compartmental Uptake Characteristics in Preoperative Glioma Using ¹⁸F-FET PET
  Johannes Lohmeier, Helena Radbruch, Winfried Brenner, Bernd Hamm, Anna Tietze and Marcus R. Makowski
  
  Journal of Nuclear Medicine November 1, 2023, 64 (11) 1683-1689; DOI: https://doi.org/10.2967/jnumed.123.265642
- You have access
  Correlation of SUV on Early Interim PET with Recurrence-Free Survival and Overall Survival in Primary Operable HER2-Positive Breast Cancer (the TBCRC026 Trial)
  Maeve A. Hennessy, Jeffrey P. Leal, Chiung-Yu Huang, Lilja B. Solnes, Rita Denbow, Vandana G. Abramson, Lisa A. Carey, Minetta C. Liu, Mothaffar Rimawi, Jennifer Specht, Anna Maria Storniolo, Vicente Valero, Christos Vaklavas, Eric P. Winer, Ian E. Krop, Antonio C. Wolff, Ashley Cimino-Mathews, Richard L. Wahl, Vered Stearns and Roisin M. Connolly
  
  Journal of Nuclear Medicine November 1, 2023, 64 (11) 1690-1696; DOI: https://doi.org/10.2967/jnumed.123.265853
- INVITED PERSPECTIVE
  - You have access
    ¹⁸F-FDG PET “Metabolic Response” to Neoadjuvant Systemic Therapy for Breast Cancer: Quo Vadis?
    Geraldine Gebhart
    
    Journal of Nuclear Medicine November 1, 2023, 64 (11) 1697-1698; DOI: https://doi.org/10.2967/jnumed.123.266303
- You have access
  High Tumor Uptake on ¹⁸F-FDOPA PET/CT Indicates Poor Prognosis in Patients with Metastatic Midgut Neuroendocrine Tumors: A Study from the Groupe d’étude des Tumeurs Endocrines and ENDOCAN-RENATEN Network
  Ophélie De Rycke, Marine Perrier, Éric Ouvrard, Clément Mennetrey, Choaib Lachachi, Aurélie Bando-Delaunay, David Morland, Bernard Goichot, David Taieb, Thomas Walter, Guillaume Cadiot, Jérôme Cros, Olivia Hentic, Philippe Ruszniewski, Rachida Lebtahi, Alessio Imperiale and Louis de Mestier
  
  Journal of Nuclear Medicine November 1, 2023, 64 (11) 1699-1705; DOI: https://doi.org/10.2967/jnumed.123.265584
- You have access
  Validation of the ΔSUV_max for Interim PET Interpretation in Diffuse Large B-Cell Lymphoma on the Basis of the GAINED Clinical Trial
  Emmanuel Itti, Paul Blanc-Durand, Alina Berriolo-Riedinger, Salim Kanoun, Françoise Kraeber-Bodéré, Michel Meignan, Elodie Gat, Steven Le Gouill, René-Olivier Casasnovas and Caroline Bodet-Milin
  
  Journal of Nuclear Medicine November 1, 2023, 64 (11) 1706-1711; DOI: https://doi.org/10.2967/jnumed.123.265871
- Open Access
  Impact of ⁶⁸Ga-FAPI PET/CT on Staging and Oncologic Management in a Cohort of 226 Patients with Various Cancers
  Stefan A. Koerber, Manuel Röhrich, Leon Walkenbach, Jakob Liermann, Peter L. Choyke, Christoph Fink, Cathrin Schroeter, Anna-Maria Spektor, Klaus Herfarth, Thomas Walle, Jeremie Calais, Hans-Ulrich Kauczor, Dirk Jaeger, Juergen Debus, Uwe Haberkorn and Frederik L. Giesel
  
  Journal of Nuclear Medicine November 1, 2023, 64 (11) 1712-1720; DOI: https://doi.org/10.2967/jnumed.123.266046

Theranostics

Clinical
- BRIEF COMMUNICATION
  - You have access
    Prediction of Resistance to ¹⁷⁷Lu-PSMA Therapy by Assessment of Baseline Circulating Tumor DNA Biomarkers
    Oliver Sartor, Elisa Ledet, Minqui Huang, Jennifer Schwartz, Alex Lieberman, Brian Lewis, Jodi Layton, Pedro Barata, Albert Jang, Madeline Hawkins, Olivia Pocha, Sree Lanka and Kendra Harris
    
    Journal of Nuclear Medicine November 1, 2023, 64 (11) 1721-1725; DOI: https://doi.org/10.2967/jnumed.123.266167
  - You have access
    [¹⁷⁷Lu]Lu-PSMA-617 Versus Docetaxel in Chemotherapy-Naïve Metastatic Castration-Resistant Prostate Cancer: Final Survival Analysis of a Phase 2 Randomized, Controlled Trial
    Swayamjeet Satapathy, Bhagwant Rai Mittal, Ashwani Sood, Chandan Krushna Das, Ravimohan Suryanarayan Mavuduru, Shikha Goyal, Jaya Shukla and Shrawan Kumar Singh
    
    Journal of Nuclear Medicine November 1, 2023, 64 (11) 1726-1729; DOI: https://doi.org/10.2967/jnumed.123.266141
- You have access
  Antihormonal-Treatment Status Affects ⁶⁸Ga-PSMA-HBED-CC PET Biodistribution in Patients with Prostate Cancer
  Kilian Kluge, David Haberl, Holger Einspieler, Sazan Rasul, Sebastian Gutschmayer, Lukas Kenner, Gero Kramer, Bernhard Grubmüller, Shahrokh Shariat, Alexander Haug and Marcus Hacker
  
  Journal of Nuclear Medicine November 1, 2023, 64 (11) 1730-1736; DOI: https://doi.org/10.2967/jnumed.123.265980
- You have access
  Prognostic Value of End-of-Treatment PSMA PET/CT in Patients Treated with ¹⁷⁷Lu-PSMA Radioligand Therapy: A Retrospective, Single-Center Analysis
  Vishnu Murthy, Andrei Gafita, Pan Thin, Kathleen Nguyen, Tristan Grogan, John Shen, Alexandra Drakaki, Matthew Rettig, Johannes Czernin and Jeremie Calais
  
  Journal of Nuclear Medicine November 1, 2023, 64 (11) 1737-1743; DOI: https://doi.org/10.2967/jnumed.122.265155
- FEATURED ARTICLE OF THE MONTH
  - You have access
    Do Bone Scans Overstage Disease Compared with PSMA PET at Initial Staging? An International Multicenter Retrospective Study with Masked Independent Readers
    Thomas A. Hope, Matthias Benz, Fei Jiang, Daniel Thompson, Francesco Barbato, Roxana Juarez, Miguel Hernandez Pampaloni, Martin Allen-Auerbach, Pawan Gupta, Wolfgang P. Fendler and Jeremie Calais
    
    Journal of Nuclear Medicine November 1, 2023, 64 (11) 1744-1747; DOI: https://doi.org/10.2967/jnumed.123.265916
- INVITED PERSPECTIVE
  - You have access
    Out with the Old, in with the New: Can We Bridge the Gap Between Clinical Trial Results Based on Bone Scans and the Era of Modern Prostate Cancer Imaging?
    Michal Eifer, Ramin Alipour, Michael S. Hofman and Aravind S. Ravi Kumar
    
    Journal of Nuclear Medicine November 1, 2023, 64 (11) 1748-1749; DOI: https://doi.org/10.2967/jnumed.123.266025
- You have access
  A Prostate-Specific Membrane Antigen PET-Based Approach for Improved Diagnosis of Prostate Cancer in Gleason Grade Group 1: A Multicenter Retrospective Study
  Jingliang Zhang, Fei Kang, Jie Gao, Jianhua Jiao, Zhiyong Quan, Shuaijun Ma, Yu Li, Shikuan Guo, Zeyu Li, Yuming Jing, Keying Zhang, Fa Yang, Donghui Han, Weihong Wen, Jing Zhang, Jing Ren, Jing Wang, Hongqian Guo and Weijun Qin
  
  Journal of Nuclear Medicine November 1, 2023, 64 (11) 1750-1757; DOI: https://doi.org/10.2967/jnumed.122.265001
- You have access
  Prediction of Response to ¹⁷⁷Lu-PSMA Therapy Based on Tumor-to-Kidney Ratio on Pretherapeutic PSMA PET/CT and Posttherapeutic Tumor-Dose Evaluation in mCRPC
  Melanie Hohberg, Manuel Reifegerst, Alexander Drzezga, Markus Wild and Matthias Schmidt
  
  Journal of Nuclear Medicine November 1, 2023, 64 (11) 1758-1764; DOI: https://doi.org/10.2967/jnumed.122.264953
- You have access
  Improved Quality of Life in Metastatic Castration-Resistant Prostate Cancer Patients Receiving Consecutive Cycles of ¹⁷⁷Lu-PSMA I&T
  Amir Karimzadeh, Paula Soeiro, Benedikt Feuerecker, Charlotte-Sophie Hecker, Karina Knorr, Matthias M. Heck, Robert Tauber, Calogero D’Alessandria, Wolfgang A. Weber, Matthias Eiber and Isabel Rauscher
  
  Journal of Nuclear Medicine November 1, 2023, 64 (11) 1765-1771; DOI: https://doi.org/10.2967/jnumed.123.265878
Basic
- Open Access
  Tandem Isotope Therapy with ²²⁵Ac- and ¹⁷⁷Lu-PSMA-617 in a Murine Model of Prostate Cancer
  Catherine Meyer, Andreea Stuparu, Katharina Lueckerath, Jeremie Calais, Johannes Czernin, Roger Slavik and Magnus Dahlbom
  
  Journal of Nuclear Medicine November 1, 2023, 64 (11) 1772-1778; DOI: https://doi.org/10.2967/jnumed.123.265433

Adiobiology/Dosimetry

Clinical
- You have access
  Lesion Dosimetry for [¹⁷⁷Lu]Lu-PSMA-617 Radiopharmaceutical Therapy Combined with Stereotactic Body Radiotherapy in Patients with Oligometastatic Castration-Sensitive Prostate Cancer
  Milan Grkovski, Joseph A. O’Donoghue, Brandon S. Imber, George Andl, Cheng Tu, Daniel Lafontaine, Jazmin Schwartz, Maria Thor, Michael J. Zelefsky, John L. Humm and Lisa Bodei
  
  Journal of Nuclear Medicine November 1, 2023, 64 (11) 1779-1787; DOI: https://doi.org/10.2967/jnumed.123.265763
- BRIEF COMMUNICATION
  - You have access
    Second Symposium of the European Working Group on the Radiobiology of Molecular Radionuclide Therapy
    Julie Nonnekens, Bart Cornelissen and Samantha Y.A. Terry; on behalf of the European Working Group on the Radiobiology of Molecular Radiotherapy
    
    Journal of Nuclear Medicine November 1, 2023, 64 (11) 1788-1790; DOI: https://doi.org/10.2967/jnumed.123.265956

Radiochemistry

Basic
- You have access
  Optimized Methods for the Production of High-Purity ²⁰³Pb Using Electroplated Thallium Targets
  Shefali Saini, Jennifer L. Bartels, Jean-Pierre K. Appiah, Jason H. Rider, Nicholas Baumhover, Michael K. Schultz and Suzanne E. Lapi
  
  Journal of Nuclear Medicine November 1, 2023, 64 (11) 1791-1797; DOI: https://doi.org/10.2967/jnumed.123.265976

Neurology

Clinical
- You have access
  Biostatistical Estimation of Tau Threshold Hallmarks (BETTH) Algorithm for Human Tau PET Imaging Studies
  Alexandra Gogola, Brian J. Lopresti, Dana Tudorascu, Beth Snitz, Davneet Minhas, Vincent Doré, Milos D. Ikonomovic, C. Elizabeth Shaaban, Cristy Matan, Pierrick Bourgeat, N. Scott Mason, Howard Aizenstein, Chester A. Mathis, William E. Klunk, Christopher C. Rowe, Oscar L. Lopez, Ann D. Cohen, Victor L. Villemagne and for the Alzheimer’s Disease Neuroimaging Initiative
  
  Journal of Nuclear Medicine November 1, 2023, 64 (11) 1798-1805; DOI: https://doi.org/10.2967/jnumed.123.265941

Gastroenterology

Basic
- FEATURED BASIC SCIENCE ARTICLE
  - You have access
    Detection of IL12/23p40 via PET Visualizes Inflammatory Bowel Disease
    Farzaneh Rezazadeh, Nicholas Ramos, Allen-Dexter Saliganan, Najeeb Al-Hallak, Kang Chen, Bashar Mohamad, Wendy N. Wiesend and Nerissa T. Viola
    
    Journal of Nuclear Medicine November 1, 2023, 64 (11) 1806-1814; DOI: https://doi.org/10.2967/jnumed.123.265649

Physics and Instrumentation

Clinical
- You have access
  Long Versus Short Axial Field of View Immuno-PET/CT: Semiquantitative Evaluation for ⁸⁹Zr-Trastuzumab
  Philipp Mohr, Joyce van Sluis, Laura Providência, Johannes H. van Snick, Marjolijn N. Lub-de Hooge, Antoon T. Willemsen, Andor W.J.M. Glaudemans, Ronald Boellaard, Adriaan A. Lammertsma, Adrienne H. Brouwers and Charalampos Tsoumpas
  
  Journal of Nuclear Medicine November 1, 2023, 64 (11) 1815-1820; DOI: https://doi.org/10.2967/jnumed.123.265621
- Open Access
  Total-Body Multiparametric PET Quantification of ¹⁸F-FDG Delivery and Metabolism in the Study of Coronavirus Disease 2019 Recovery
  Yiran Wang, Lorenzo Nardo, Benjamin A. Spencer, Yasser G. Abdelhafez, Elizabeth J. Li, Negar Omidvari, Abhijit J. Chaudhari, Ramsey D. Badawi, Terry Jones, Simon R. Cherry and Guobao Wang
  
  Journal of Nuclear Medicine November 1, 2023, 64 (11) 1821-1830; DOI: https://doi.org/10.2967/jnumed.123.265723
- You have access
  Total-Body Perfusion Imaging with [¹¹C]-Butanol
  Elizabeth J. Li, Javier E. López, Benjamin A. Spencer, Yasser Abdelhafez, Ramsey D. Badawi, Guobao Wang and Simon R. Cherry
  
  Journal of Nuclear Medicine November 1, 2023, 64 (11) 1831-1838; DOI: https://doi.org/10.2967/jnumed.123.265659

Illustrated Post

You have access
Obstructive Sialadenitis from Oral Squamous Cell Carcinoma: [⁶⁸Ga]Ga-FAPI-46 PET–Positive and [¹⁸F]FDG PET–Negative
Peter George Maliha, Abie H. Mendelsohn, Johannes Czernin, Taylor Howard, Jeremie Calais and Masatoshi Hotta

Journal of Nuclear Medicine November 1, 2023, 64 (11) 1839-1840; DOI: https://doi.org/10.2967/jnumed.123.265498

Letters to the Editor

You have access
HER2-Low Breast Cancer Can Be Visualized by HER2 PET
Renske Altena, Siri af Burén, Thuy Tran and Rimma Axelsson

Journal of Nuclear Medicine November 1, 2023, 64 (11) 1841; DOI: https://doi.org/10.2967/jnumed.123.266101
You have access
Reply to: HER2-Low Breast Cancer Can Be Visualized by HER2 PET
Romain-David Seban

Journal of Nuclear Medicine November 1, 2023, 64 (11) 1841-1842; DOI: https://doi.org/10.2967/jnumed.123.266490