Journal of Nuclear Medicine: 59 (4)

April 1, 2018; Volume 59,Issue 4

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine April 1, 2018, 59 (4) 8A;

Hot Topics

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Gauging Cardiac Repair and Regeneration with New Molecular Probes
James T. Thackeray and Frank M. Bengel

Journal of Nuclear Medicine April 1, 2018, 59 (4) 549-550; DOI: https://doi.org/10.2967/jnumed.117.198283

The State of the Art

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¹⁸F-FDG PET/CT in Local Ablative Therapies: A Systematic Review
Erik H.J.G. Aarntzen, Linda Heijmen and Wim J.G. Oyen

Journal of Nuclear Medicine April 1, 2018, 59 (4) 551-556; DOI: https://doi.org/10.2967/jnumed.117.198184

Continuing Education

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The Utility of PET/CT in the Planning of External Radiation Therapy for Prostate Cancer
Jeremie Calais, Minsong Cao and Nicholas G. Nickols

Journal of Nuclear Medicine April 1, 2018, 59 (4) 557-567; DOI: https://doi.org/10.2967/jnumed.117.196444

Focus on Molecular Imaging

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Recent Advances in ¹⁸F Radiochemistry: A Focus on B-¹⁸F, Si-¹⁸F, Al-¹⁸F, and C-¹⁸F Radiofluorination via Spirocyclic Iodonium Ylides
Vadim Bernard-Gauthier, Mathieu L. Lepage, Bjoern Waengler, Justin J. Bailey, Steven H. Liang, David M. Perrin, Neil Vasdev and Ralf Schirrmacher

Journal of Nuclear Medicine April 1, 2018, 59 (4) 568-572; DOI: https://doi.org/10.2967/jnumed.117.197095

Editorial

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New Challenges in Nuclear Endocrinology
David Taïeb, Rodney J. Hicks and Karel Pacak

Journal of Nuclear Medicine April 1, 2018, 59 (4) 573-574; DOI: https://doi.org/10.2967/jnumed.117.199729

Oncology

Clinical
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  A PET/CT-Based Strategy Is a Stronger Predictor of Survival Than a Standard Imaging Strategy in Patients with Head and Neck Squamous Cell Carcinoma
  Max Rohde, Anne L. Nielsen, Manan Pareek, Jørgen Johansen, Jens A. Sørensen, Anabel Diaz, Mie K. Nielsen, Janus M. Christiansen, Jon T. Asmussen, Nina Nguyen, Oke Gerke, Anders Thomassen, Abass Alavi, Poul Flemming Høilund-Carlsen and Christian Godballe
  
  Journal of Nuclear Medicine April 1, 2018, 59 (4) 575-581; DOI: https://doi.org/10.2967/jnumed.117.197350
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  Efficacy of Radioembolization with ¹⁶⁶Ho-Microspheres in Salvage Patients with Liver Metastases: A Phase 2 Study
  Jip F. Prince, Maurice A.A.J. van den Bosch, Johannes F.W. Nijsen, Maarten L.J. Smits, Andor F. van den Hoven, Stavros Nikolakopoulos, Frank J. Wessels, Rutger C.G. Bruijnen, Manon N.G.J.A. Braat, Bernard A. Zonnenberg and Marnix G.E.H. Lam
  
  Journal of Nuclear Medicine April 1, 2018, 59 (4) 582-588; DOI: https://doi.org/10.2967/jnumed.117.197194
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  Predictive Value of PET Response Combined with Baseline Metabolic Tumor Volume in Peripheral T-Cell Lymphoma Patients
  Anne-Ségolène Cottereau, Tarec Christoffer El-Galaly, Stéphanie Becker, Florence Broussais, Lars Jelstrup Petersen, Christophe Bonnet, John O. Prior, Hervé Tilly, Martin Hutchings, Olivier Casasnovas and Michel Meignan
  
  Journal of Nuclear Medicine April 1, 2018, 59 (4) 589-595; DOI: https://doi.org/10.2967/jnumed.117.193946
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  ²²³Ra Therapy of Advanced Metastatic Castration-Resistant Prostate Cancer: Quantitative Assessment of Skeletal Tumor Burden for Prognostication of Clinical Outcome and Hematologic Toxicity
  Marie Øbro Fosbøl, Peter Meidahl Petersen, Andreas Kjaer and Jann Mortensen
  
  Journal of Nuclear Medicine April 1, 2018, 59 (4) 596-602; DOI: https://doi.org/10.2967/jnumed.117.195677
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  Spatial Relationship of Glioma Volume Derived from ¹⁸F-FET PET and Volumetric MR Spectroscopy Imaging: A Hybrid PET/MRI Study
  Jörg Mauler, Andrew A. Maudsley, Karl-Josef Langen, Omid Nikoubashman, Gabriele Stoffels, Sulaiman Sheriff, Philipp Lohmann, Christian Filss, Norbert Galldiks, Elena Rota Kops and N. Jon Shah
  
  Journal of Nuclear Medicine April 1, 2018, 59 (4) 603-609; DOI: https://doi.org/10.2967/jnumed.117.196709
- INVITED PERSPECTIVE
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    Immuno-PET in Pontine Glioma: More Than Meets the Eye?
    Wim J.G. Oyen and Chris Jones
    
    Journal of Nuclear Medicine April 1, 2018, 59 (4) 610-611; DOI: https://doi.org/10.2967/jnumed.117.200527
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  Multiregional Tumor Drug-Uptake Imaging by PET and Microvascular Morphology in End-Stage Diffuse Intrinsic Pontine Glioma
  Sophie E.M. Veldhuijzen van Zanten, A. Charlotte P. Sewing, Arthur van Lingen, Otto S. Hoekstra, Pieter Wesseling, Michaël H. Meel, Dannis G. van Vuurden, Gertjan J.L. Kaspers, Esther Hulleman and Marianna Bugiani
  
  Journal of Nuclear Medicine April 1, 2018, 59 (4) 612-615; DOI: https://doi.org/10.2967/jnumed.117.197897

Theranostics

Clinical
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  Optimizing Image Quantification for ¹⁷⁷Lu SPECT/CT Based on a 3D Printed 2-Compartment Kidney Phantom
  Johannes Tran-Gia and Michael Lassmann
  
  Journal of Nuclear Medicine April 1, 2018, 59 (4) 616-624; DOI: https://doi.org/10.2967/jnumed.117.200170
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  Cold Kit for Prostate-Specific Membrane Antigen (PSMA) PET Imaging: Phase 1 Study of ⁶⁸Ga-Tris(Hydroxypyridinone)-PSMA PET/CT in Patients with Prostate Cancer
  Michael S. Hofman, Peter Eu, Price Jackson, Emily Hong, David Binns, Amir Iravani, Declan Murphy, Catherine Mitchell, Shankar Siva, Rodney J. Hicks, Jennifer D. Young, Philip J. Blower and Gregory E. Mullen
  
  Journal of Nuclear Medicine April 1, 2018, 59 (4) 625-631; DOI: https://doi.org/10.2967/jnumed.117.199554
- BRIEF COMMUNICATION
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    Biochemical Recurrence of Prostate Cancer: Initial Results with [¹⁸F]PSMA-1007 PET/CT
    Frederik L. Giesel, Leon Will, Claudia Kesch, Martin Freitag, Christophe Kremer, Jonas Merkle, Oliver C. Neels, Jens Cardinale, Boris Hadaschik, Markus Hohenfellner, Klaus Kopka, Uwe Haberkorn and Clemens Kratochwil
    
    Journal of Nuclear Medicine April 1, 2018, 59 (4) 632-635; DOI: https://doi.org/10.2967/jnumed.117.196329
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    Accuracy of Dose Calibrators for ⁶⁸Ga PET Imaging: Unexpected Findings in a Multicenter Clinical Pretrial Assessment
    Dale L. Bailey, Michael S. Hofman, Nicholas J. Forwood, Graeme J. O’Keefe, Andrew M. Scott, Winifred M. van Wyngaardt, Bonnie Howe, Olga Kovacev and Roslyn J. Francis; on behalf of ARTnet; and the ProPSMA Trial Investigators
    
    Journal of Nuclear Medicine April 1, 2018, 59 (4) 636-638; DOI: https://doi.org/10.2967/jnumed.117.202861
Basic
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  PSMA-11–Derived Dual-Labeled PSMA Inhibitors for Preoperative PET Imaging and Precise Fluorescence-Guided Surgery of Prostate Cancer
  Ann-Christin Baranski, Martin Schäfer, Ulrike Bauder-Wüst, Mareike Roscher, Jana Schmidt, Esther Stenau, Tobias Simpfendörfer, Dogu Teber, Lena Maier-Hein, Boris Hadaschik, Uwe Haberkorn, Matthias Eder and Klaus Kopka
  
  Journal of Nuclear Medicine April 1, 2018, 59 (4) 639-645; DOI: https://doi.org/10.2967/jnumed.117.201293
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  Model of Intraperitoneal Targeted α-Particle Therapy Shows That Posttherapy Cold-Antibody Boost Enhances Microtumor Radiation Dose and Treatable Tumor Sizes
  Stig Palm, Tom Bäck, Sture Lindegren, Ragnar Hultborn, Lars Jacobsson and Per Albertsson
  
  Journal of Nuclear Medicine April 1, 2018, 59 (4) 646-651; DOI: https://doi.org/10.2967/jnumed.117.201285

Cardiology

Clinical
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  Quantification and Determination of Normal ¹²³I-Meta Iodobenzylguanidine Heart-to-Mediastinum Ratio (HMR) from Cardiac SPECT/CT and Correlation with Planar HMR
  Raza Alvi, Edward J. Miller, Taraneh Hashemi Zonouz, Veronica Sandoval, Noor Tariq, Rachel Lampert, Albert J. Sinusas and Yi-Hwa Liu
  
  Journal of Nuclear Medicine April 1, 2018, 59 (4) 652-658; DOI: https://doi.org/10.2967/jnumed.117.197152

Neurology

Clinical
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  Noradrenergic Deficits in Parkinson Disease Imaged with ¹¹C-MeNER
  Adjmal Nahimi, Michael Sommerauer, Martin B. Kinnerup, Karen Østergaard, Michael Wintherdahl, Jan Jacobsen, Anna Schacht, Birger Johnsen, Malene F. Damholdt, Per Borghammer and Albert Gjedde
  
  Journal of Nuclear Medicine April 1, 2018, 59 (4) 659-664; DOI: https://doi.org/10.2967/jnumed.117.190975
- FEATURED CLINICAL INVESTIGATION ARTICLE
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    Decreased Pretreatment Amygdalae Serotonin Transporter Binding in Unipolar Depression Remitters: A Prospective PET Study
    Mala R. Ananth, Christine DeLorenzo, Jie Yang, J. John Mann and Ramin V. Parsey
    
    Journal of Nuclear Medicine April 1, 2018, 59 (4) 665-670; DOI: https://doi.org/10.2967/jnumed.117.189654
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  Correlations of ¹⁸F-THK5351 PET with Postmortem Burden of Tau and Astrogliosis in Alzheimer Disease
  Ryuichi Harada, Aiko Ishiki, Hideaki Kai, Naomi Sato, Katsutoshi Furukawa, Shozo Furumoto, Tetsuro Tago, Naoki Tomita, Shoichi Watanuki, Kotaro Hiraoka, Yoichi Ishikawa, Yoshihito Funaki, Tadaho Nakamura, Takeo Yoshikawa, Ren Iwata, Manabu Tashiro, Hironobu Sasano, Tetsuyuki Kitamoto, Kazuhiko Yanai, Hiroyuki Arai, Yukitsuka Kudo and Nobuyuki Okamura
  
  Journal of Nuclear Medicine April 1, 2018, 59 (4) 671-674; DOI: https://doi.org/10.2967/jnumed.117.197426
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  Preclinical Evaluation of ¹⁸F-RO6958948, ¹¹C-RO6931643, and ¹¹C-RO6924963 as Novel PET Radiotracers for Imaging Tau Aggregates in Alzheimer Disease
  Michael Honer, Luca Gobbi, Henner Knust, Hiroto Kuwabara, Dieter Muri, Matthias Koerner, Heather Valentine, Robert F. Dannals, Dean F. Wong and Edilio Borroni
  
  Journal of Nuclear Medicine April 1, 2018, 59 (4) 675-681; DOI: https://doi.org/10.2967/jnumed.117.196741
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  Lower Limbic Metabotropic Glutamate Receptor 5 Availability in Alcohol Dependence
  Gil Leurquin-Sterk, Jenny Ceccarini, Cleo L. Crunelle, Bart de Laat, Jef Verbeek, Stephanie Deman, Hugo Neels, Guy Bormans, Hendrik Peuskens and Koen Van Laere
  
  Journal of Nuclear Medicine April 1, 2018, 59 (4) 682-690; DOI: https://doi.org/10.2967/jnumed.117.199422

Gastroenterology

Clinical
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  Intragastric Meal Distribution During Gastric Emptying Scintigraphy for Assessment of Fundic Accommodation: Correlation with Symptoms of Gastroparesis
  Perry Orthey, Daohai Yu, Mark L. Van Natta, Frederick V. Ramsey, Jesus R. Diaz, Paige A. Bennett, Andrei H. Iagaru, Roberto Salas Fragomeni, Richard W. McCallum, Irene Sarosiek, William L. Hasler, Gianrico Farrugia, Madhusudan Grover, Kenneth L. Koch, Linda Nguyen, William J. Snape, Thomas L. Abell, Pankaj J. Pasricha, James Tonascia, Frank Hamilton, Henry P. Parkman and Alan H. Maurer; for the NIH Gastroparesis Consortium
  
  Journal of Nuclear Medicine April 1, 2018, 59 (4) 691-697; DOI: https://doi.org/10.2967/jnumed.117.197053

Radiochemistry

Basic
- FEATURED ARTICLE OF THE MONTH
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    Evaluation of ¹¹C-Me-NB1 as a Potential PET Radioligand for Measuring GluN2B-Containing NMDA Receptors, Drug Occupancy, and Receptor Cross Talk
    Stefanie D. Krämer, Thomas Betzel, Linjing Mu, Achi Haider, Adrienne Müller Herde, Anna K. Boninsegni, Claudia Keller, Marina Szermerski, Roger Schibli, Bernhard Wünsch and Simon M. Ametamey
    
    Journal of Nuclear Medicine April 1, 2018, 59 (4) 698-703; DOI: https://doi.org/10.2967/jnumed.117.200451

Radiobiology/Dosimetry

Clinical
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  Biodistribution and Dosimetry Results from a Phase 1 Trial of Therapy with the Antibody–Radionuclide Conjugate ¹⁷⁷Lu-Lilotomab Satetraxetan
  Johan Blakkisrud, Jon Erik Holtedahl, Ayca Løndalen, Jostein Dahle, Tore Bach-Gansmo, Harald Holte, Stine Nygaard, Arne Kolstad and Caroline Stokke
  
  Journal of Nuclear Medicine April 1, 2018, 59 (4) 704-710; DOI: https://doi.org/10.2967/jnumed.117.195347

Errata

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Erratum
Journal of Nuclear Medicine April 1, 2018, 59 (4) 710;
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Erratum
Journal of Nuclear Medicine April 1, 2018, 59 (4) 710;

Letters to the Editor

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Optimizing Strategies for Immune Checkpoint Imaging with Immuno-PET in Preclinical Study
Jiale Chen, Ning Wang, Xinyu Yang and Yuan Li

Journal of Nuclear Medicine April 1, 2018, 59 (4) 711; DOI: https://doi.org/10.2967/jnumed.117.204685
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Reply: Optimizing Strategies for Immune Checkpoint Imaging with Immuno-PET in Preclinical Study
Aaron T. Mayer and Sanjiv S. Gambhir

Journal of Nuclear Medicine April 1, 2018, 59 (4) 711-712; DOI: https://doi.org/10.2967/jnumed.117.205153
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Doxorubicin Effect on Myocardial Metabolism as a Prerequisite for Subsequent Development of Cardiac Toxicity: Are There Unsuspected Confounders?
Monica Finessi, Daniele G. Nicolotti, Gianni Bisi and Désirée Deandreis

Journal of Nuclear Medicine April 1, 2018, 59 (4) 713; DOI: https://doi.org/10.2967/jnumed.117.205856
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Reply: Doxorubicin Effect on Myocardial Metabolism as a Prerequisite for Subsequent Development of Cardiac Toxicity: Are There Unsuspected Confounders?
Gianmario Sambuceti, Silvia Morbelli, Vanessa Cossu, Cecilia Marini and Matteo Bauckneht

Journal of Nuclear Medicine April 1, 2018, 59 (4) 713-714; DOI: https://doi.org/10.2967/jnumed.117.206797
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Staging, Restaging, and Treatment Response Assessment in Lymphomas: What We Should Know
Salim Kanoun, Anne-Segolène Cottereau, Alina Berriolo-Riedinger, Michel Meignan, Olivier Casasnovas, Fréderic Courbon and Françoise Kraeber-Bodéré

Journal of Nuclear Medicine April 1, 2018, 59 (4) 714-715; DOI: https://doi.org/10.2967/jnumed.117.205351
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Reply: Staging, Restaging, and Treatment Response Assessment in Lymphomas: What We Should Know
Roberto Delgado-Bolton, Giuseppe Esposito, Patrick M. Colletti and Hossein Jadvar

Journal of Nuclear Medicine April 1, 2018, 59 (4) 715-716; DOI: https://doi.org/10.2967/jnumed.117.206946
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Molecular Imaging of Bacteria in Patients Is an Attractive Fata Morgana, Not a Realistic Option
Søren Hess, Abass Alavi, Tom Werner and Poul Flemming Høilund-Carlsen

Journal of Nuclear Medicine April 1, 2018, 59 (4) 716-717; DOI: https://doi.org/10.2967/jnumed.117.207001
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Reply: Molecular Imaging of Bacteria in Patients Is an Attractive Fata Morgana, Not a Realistic Option
Ismaheel Lawal, Alfred Ankrah and Mike Sathekge

Journal of Nuclear Medicine April 1, 2018, 59 (4) 717; DOI: https://doi.org/10.2967/jnumed.118.208595
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Cerebrospinal Fluid, Hyposmia, and Dementia in Alzheimer Disease: Insights from Dynamic PET and a Hypothesis
Ashwin Kumaria

Journal of Nuclear Medicine April 1, 2018, 59 (4) 718; DOI: https://doi.org/10.2967/jnumed.117.206888
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Reply: Cerebrospinal Fluid, Hyposmia, and Dementia in Alzheimer Disease: Insights from Dynamic PET and a Hypothesis
Mony J. de Leon, Yi Li and Henry Rusinek

Journal of Nuclear Medicine April 1, 2018, 59 (4) 718-719; DOI: https://doi.org/10.2967/jnumed.117.207068
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Research, Research, Otherwise We Are lost!
Ozgul Ekmekcioglu

Journal of Nuclear Medicine April 1, 2018, 59 (4) 719; DOI: https://doi.org/10.2967/jnumed.117.206383

SNMMI Newsline

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FDA Approves Lutathera for GEP NET Therapy
Journal of Nuclear Medicine April 1, 2018, 59 (4) 9N;
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Nuclear Medicine Procedure Performance and Cataracts
Journal of Nuclear Medicine April 1, 2018, 59 (4) 10N;
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New Test for PD and DLB
Journal of Nuclear Medicine April 1, 2018, 59 (4) 10N;
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Domestic Non-Uranium-Based ^99mTc Production System Approved
Journal of Nuclear Medicine April 1, 2018, 59 (4) 11N;
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NAD⁺ Supplementation in Mouse AD Model
Journal of Nuclear Medicine April 1, 2018, 59 (4) 12N;
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What Patients Want to Know Before Imaging
Journal of Nuclear Medicine April 1, 2018, 59 (4) 12N;
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SNMMI Leadership Update: The SNMMI Annual Meeting: Making History in Philadelphia
Virginia Pappas

Journal of Nuclear Medicine April 1, 2018, 59 (4) 13N-20N;
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Newsbriefs
Journal of Nuclear Medicine April 1, 2018, 59 (4) 14N-15N;
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From The Literature
Journal of Nuclear Medicine April 1, 2018, 59 (4) 16N-20N;

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Table of Contents

This Month in JNM

Hot Topics

The State of the Art

Continuing Education

Focus on Molecular Imaging

Editorial

Oncology

Clinical

INVITED PERSPECTIVE

Theranostics

Clinical

BRIEF COMMUNICATION

Basic

Cardiology

Clinical

Neurology

Clinical

FEATURED CLINICAL INVESTIGATION ARTICLE

Gastroenterology

Clinical

Radiochemistry

Basic

FEATURED ARTICLE OF THE MONTH

Radiobiology/Dosimetry

Clinical

Errata

Letters to the Editor

SNMMI Newsline

In this issue

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