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Research ArticleLaboratory Studies

Synthesis and Preliminary Evaluation of Carbon-11-Meta-Hydroxyephedrine: A False Transmitter Agent for Heart Neuronal Imaging

Karen C. Rosenspire, Michael S. Haka, Marcian E. Van Dort, Douglas M. Jewett, David L. Gildersleeve, Markus Schwaiger and Donald M. Wieland
Journal of Nuclear Medicine August 1990, 31 (8) 1328-1334;
Karen C. Rosenspire
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Michael S. Haka
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Marcian E. Van Dort
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Douglas M. Jewett
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David L. Gildersleeve
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Markus Schwaiger
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Donald M. Wieland
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Journal of Nuclear Medicine
Vol. 31, Issue 8
August 1, 1990
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Synthesis and Preliminary Evaluation of Carbon-11-Meta-Hydroxyephedrine: A False Transmitter Agent for Heart Neuronal Imaging
Karen C. Rosenspire, Michael S. Haka, Marcian E. Van Dort, Douglas M. Jewett, David L. Gildersleeve, Markus Schwaiger, Donald M. Wieland
Journal of Nuclear Medicine Aug 1990, 31 (8) 1328-1334;

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Synthesis and Preliminary Evaluation of Carbon-11-Meta-Hydroxyephedrine: A False Transmitter Agent for Heart Neuronal Imaging
Karen C. Rosenspire, Michael S. Haka, Marcian E. Van Dort, Douglas M. Jewett, David L. Gildersleeve, Markus Schwaiger, Donald M. Wieland
Journal of Nuclear Medicine Aug 1990, 31 (8) 1328-1334;
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  • Evidence for Pre- to Postsynaptic Mismatch of the Cardiac Sympathetic Nervous System in Ischemic Congestive Heart Failure
  • Presence of Specific 11C-meta-Hydroxyephedrine Retention in Heart, Lung, Pancreas, and Brown Adipose Tissue
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  • Whole-Body PET/CT with 11C-Meta-Hydroxyephedrine in Tumors of the Sympathetic Nervous System: Feasibility Study and Comparison with 123I-MIBG SPECT/CT
  • Dependence of Cardiac 11C-meta-Hydroxyephedrine Retention on Norepinephrine Transporter Density
  • Regional 11C-Hydroxyephedrine Retention in Hibernating Myocardium: Chronic Inhomogeneity of Sympathetic Innervation in the Absence of Infarction
  • Exercise Training in Chronic Heart Failure: Beneficial Effects on Cardiac 11C-Hydroxyephedrine PET, Autonomic Nervous Control, and Ventricular Repolarization
  • Reappearance of Cardiac Presynaptic Sympathetic Nerve Terminals in the Transplanted Heart: Correlation Between PET Using 11C-Hydroxyephedrine and Invasively Measured Norepinephrine Release
  • Cardiac Neurotransmission Imaging
  • Myocardial Efficiency and Sympathetic Reinnervation After Orthotopic Heart Transplantation : A Noninvasive Study With Positron Emission Tomography
  • Abnormalities of Cardiac Sympathetic Innervation in Arrhythmogenic Right Ventricular Cardiomyopathy : Quantitative Assessment of Presynaptic Norepinephrine Reuptake and Postsynaptic {beta}-Adrenergic Receptor Density With Positron Emission Tomography
  • Evaluation of Sympathetic Nerve Terminals With [11C]Epinephrine and [11C]Hydroxyephedrine and Positron Emission Tomography
  • Serial Assessment of Sympathetic Reinnervation After Orthotopic Heart Transplantation : A Longitudinal Study Using PET and C-11 Hydroxyephedrine
  • Regional patterns of myocardial sympathetic denervation in dilated cardiomyopathy: an analysis using carbon-11 hydroxyephedrine and positron emission tomography
  • Cardiac Sympathetic Dysinnervation in Diabetes : Implications for Enhanced Cardiovascular Risk
  • Cardiac sympathetic innervation in patients with idiopathic right ventricular outflow tract tachycardia
  • Scintigraphic Assessment of Regionalized Defects in Myocardial Sympathetic Innervation and Blood Flow Regulation in Diabetic Patients With Autonomic Neuropathy
  • Myocardial Presynaptic and Postsynaptic Autonomic Dysfunction in Hypertrophic Cardiomyopathy
  • Imaging of cardiac neuronal function after cocaine exposure using Carbon-11 hydroxyephedrine and positron emission tomography
  • Noninvasive assessment of cardiac diabetic neuropathy by carbon-11 hydroxyephedrine and positron emission tomography
  • Carbon-11 hydroxyephedrine with positron emission tomography for serial assessment of cardiac adrenergic neuronal function after acute myocardial infarction in humans
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