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Journal of Nuclear Medicine

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Research ArticleFocus on Molecular Imaging

Recent Advances in Imaging Steroid Hormone Receptors in Breast Cancer

Manoj Kumar, Kelley Salem, Amye J. Tevaarwerk, Roberta M. Strigel and Amy M. Fowler
Journal of Nuclear Medicine February 2020, 61 (2) 172-176; DOI: https://doi.org/10.2967/jnumed.119.228858
Manoj Kumar
1Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
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Kelley Salem
1Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
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Amye J. Tevaarwerk
2University of Wisconsin Carbone Cancer Center, Madison, Wisconsin
3Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin; and
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Roberta M. Strigel
1Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
2University of Wisconsin Carbone Cancer Center, Madison, Wisconsin
4Department of Medical Physics, University of Wisconsin, Madison, Wisconsin
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Amy M. Fowler
1Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
2University of Wisconsin Carbone Cancer Center, Madison, Wisconsin
4Department of Medical Physics, University of Wisconsin, Madison, Wisconsin
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    FIGURE 1.

    18F-fluoroestradiol PET/CT images of a postmenopausal woman with invasive ductal carcinoma (ER-positive, PR-positive, HER2-negative) and histologically confirmed metastatic disease show uptake in a left supraclavicular lymph node that does not meet size criteria for anatomic enlargement (A, arrow) and retroperitoneal lymph nodes (B, arrow). Physiologic clearance is noted in small bowel.

  • FIGURE 2.
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    FIGURE 2.

    18F-FFNP PET/CT images of a postmenopausal woman with invasive lobular carcinoma (grade 2, ER-positive, PR-positive, HER2-negative) show uptake in biopsy-proven left breast malignancy (A, yellow arrow), left internal mammary lymph node (A, red arrow) and left level 1 axillary lymph node (B, arrow).

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Journal of Nuclear Medicine: 61 (2)
Journal of Nuclear Medicine
Vol. 61, Issue 2
February 1, 2020
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Recent Advances in Imaging Steroid Hormone Receptors in Breast Cancer
Manoj Kumar, Kelley Salem, Amye J. Tevaarwerk, Roberta M. Strigel, Amy M. Fowler
Journal of Nuclear Medicine Feb 2020, 61 (2) 172-176; DOI: 10.2967/jnumed.119.228858

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Recent Advances in Imaging Steroid Hormone Receptors in Breast Cancer
Manoj Kumar, Kelley Salem, Amye J. Tevaarwerk, Roberta M. Strigel, Amy M. Fowler
Journal of Nuclear Medicine Feb 2020, 61 (2) 172-176; DOI: 10.2967/jnumed.119.228858
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  • Article
    • Abstract
    • 18F-BASED RADIOLIGANDS FOR IMAGING ER
    • IMAGING PR USING 18F-BASED RADIOLIGANDS
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Keywords

  • estrogen receptor
  • progesterone receptor
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  • breast cancer
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