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Journal of Nuclear Medicine

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Table of Contents

February 1, 2020; Volume 61,Issue 2

This Month in JNM

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    This Month in JNM
    Journal of Nuclear Medicine February 1, 2020, 61 (2) 6A;

Hot Topics

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    FAP: The Next Billion Dollar Nuclear Theranostics Target?
    Jeremie Calais
    Journal of Nuclear Medicine February 1, 2020, 61 (2) 163-165; DOI: https://doi.org/10.2967/jnumed.119.241232

The State of the Art

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    The Spatial-Temporal Ordering of Amyloid Pathology and Opportunities for PET Imaging
    Enrico Fantoni, Lyduine Collij, Isadora Lopes Alves, Christopher Buckley and Gill Farrar; on behalf of the AMYPAD consortium
    Journal of Nuclear Medicine February 1, 2020, 61 (2) 166-171; DOI: https://doi.org/10.2967/jnumed.119.235879

Focus on Molecular Imaging

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    Recent Advances in Imaging Steroid Hormone Receptors in Breast Cancer
    Manoj Kumar, Kelley Salem, Amye J. Tevaarwerk, Roberta M. Strigel and Amy M. Fowler
    Journal of Nuclear Medicine February 1, 2020, 61 (2) 172-176; DOI: https://doi.org/10.2967/jnumed.119.228858

Oncology

  • Clinical

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      The Genetic Duet of BRAF V600E and TERT Promoter Mutations Robustly Predicts Loss of Radioiodine Avidity in Recurrent Papillary Thyroid Cancer
      Jiajun Liu, Rengyun Liu, Xiaopei Shen, Guangwu Zhu, Biao Li and Mingzhao Xing
      Journal of Nuclear Medicine February 1, 2020, 61 (2) 177-182; DOI: https://doi.org/10.2967/jnumed.119.227652
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      Prospective Comparison of PET Imaging with PSMA-Targeted 18F-DCFPyL Versus Na18F for Bone Lesion Detection in Patients with Metastatic Prostate Cancer
      Steven P. Rowe, Xin Li, Bruce J. Trock, Rudolf A. Werner, Sarah Frey, Michael DiGianvittorio, J. Keith Bleiler, Diane K. Reyes, Rehab Abdallah, Kenneth J. Pienta, Michael A. Gorin and Martin G. Pomper
      Journal of Nuclear Medicine February 1, 2020, 61 (2) 183-188; DOI: https://doi.org/10.2967/jnumed.119.227793
    • BRIEF COMMUNICATION

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        Can the Injected Dose Be Reduced in 68Ga-PSMA-11 PET/CT While Maintaining High Image Quality for Lesion Detection?
        Isabel Rauscher, Wolfgang P. Fendler, Thomas A. Hope, Andrew Quon, Stephan G. Nekolla, Jeremie Calais, Antonia Richter, Bernhard Haller, Ken Herrmann, Wolfgang A. Weber, Johannes Czernin and Matthias Eiber
        Journal of Nuclear Medicine February 1, 2020, 61 (2) 189-193; DOI: https://doi.org/10.2967/jnumed.119.227207
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      Detection Rate and Localization of Prostate Cancer Recurrence Using 68Ga-PSMA-11 PET/MRI in Patients with Low PSA Values ≤ 0.5 ng/mL
      Benedikt Kranzbühler, Julian Müller, Anton S. Becker, Helena I. Garcia Schüler, Urs Muehlematter, Christian D. Fankhauser, Sarah Kedzia, Matthias Guckenberger, Philipp A. Kaufmann, Daniel Eberli and Irene A. Burger
      Journal of Nuclear Medicine February 1, 2020, 61 (2) 194-201; DOI: https://doi.org/10.2967/jnumed.118.225276
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      An 18F-Labeled PSMA Ligand for PET/CT of Prostate Cancer: First-in-Humans Observational Study and Clinical Experience with 18F-JK-PSMA-7 During the First Year of Application
      Felix Dietlein, Melanie Hohberg, Carsten Kobe, Boris D. Zlatopolskiy, Philipp Krapf, Heike Endepols, Philipp Täger, Jochen Hammes, Axel Heidenreich, Bernd Neumaier, Alexander Drzezga and Markus Dietlein
      Journal of Nuclear Medicine February 1, 2020, 61 (2) 202-209; DOI: https://doi.org/10.2967/jnumed.119.229542
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      Lesion Detection and Interobserver Agreement with Advanced Image Reconstruction for 18F-DCFPyL PET/CT in Patients with Biochemically Recurrent Prostate Cancer
      Bernard H.E. Jansen, Robin W. Jansen, Maurits Wondergem, Sandra Srbljin, John M.H. de Klerk, Birgit I. Lissenberg-Witte, André N. Vis, Reindert J.A. van Moorselaar, Ronald Boellaard, Otto S. Hoekstra and Daniela E. Oprea-Lager
      Journal of Nuclear Medicine February 1, 2020, 61 (2) 210-216; DOI: https://doi.org/10.2967/jnumed.118.222513
    • BRIEF COMMUNICATION

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        Tumor-to-Blood Ratio for Assessment of Somatostatin Receptor Density in Neuroendocrine Tumors Using 68Ga-DOTATOC and 68Ga-DOTATATE
        Ezgi Ilan, Irina Velikyan, Mattias Sandström, Anders Sundin and Mark Lubberink
        Journal of Nuclear Medicine February 1, 2020, 61 (2) 217-221; DOI: https://doi.org/10.2967/jnumed.119.228072

Theranostics

  • Clinical

    • SPECIAL CONTRIBUTION

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        NANETS/SNMMI Consensus Statement on Patient Selection and Appropriate Use of 177Lu-DOTATATE Peptide Receptor Radionuclide Therapy
        Thomas A. Hope, Lisa Bodei, Jennifer A. Chan, Ghassan El-Haddad, Nicholas Fidelman, Pamela L. Kunz, Josh Mailman, Yusuf Menda, David C. Metz, Erik S. Mittra, Daniel A. Pryma, Diane L. Reidy-Lagunes, Simron Singh and Jonathan R. Strosberg
        Journal of Nuclear Medicine February 1, 2020, 61 (2) 222-227; DOI: https://doi.org/10.2967/jnumed.119.240911
  • Basic

    • FEATURED BASIC SCIENCE ARTICLE

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        Improving Contrast and Detectability: Imaging with [55Co]Co-DOTATATE in Comparison with [64Cu]Cu-DOTATATE and [68Ga]Ga-DOTATATE
        Thomas L. Andersen, Christina Baun, Birgitte B. Olsen, Johan H. Dam and Helge Thisgaard
        Journal of Nuclear Medicine February 1, 2020, 61 (2) 228-233; DOI: https://doi.org/10.2967/jnumed.119.233015
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      Hybrid Tracers Based on Cyanine Backbones Targeting Prostate-Specific Membrane Antigen: Tuning Pharmacokinetic Properties and Exploring Dye–Protein Interaction
      Albertus W. Hensbergen, Tessa Buckle, Danny M. van Willigen, Margret Schottelius, Mick M. Welling, Felicia A. van der Wijk, Tobias Maurer, Henk G. van der Poel, Gabri van der Pluijm, Wytske M. van Weerden, Hans-Jürgen Wester and Fijs W.B. van Leeuwen
      Journal of Nuclear Medicine February 1, 2020, 61 (2) 234-241; DOI: https://doi.org/10.2967/jnumed.119.233064

Radionuclide Therapy

  • Basic

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      131I-IITM and 211At-AITM: Two Novel Small-Molecule Radiopharmaceuticals Targeting Oncoprotein Metabotropic Glutamate Receptor 1
      Lin Xie, Masayuki Hanyu, Masayuki Fujinaga, Yiding Zhang, Kuan Hu, Katsuyuki Minegishi, Cuiping Jiang, Fuki Kurosawa, Yukie Morokoshi, Huizi Keiko Li, Sumitaka Hasegawa, Kotaro Nagatsu and Ming-Rong Zhang
      Journal of Nuclear Medicine February 1, 2020, 61 (2) 242-248; DOI: https://doi.org/10.2967/jnumed.119.230946

Cardiovascular

  • Clinical

    • FEATURED ARTICLE OF THE MONTH

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        Comparative Prognostic and Diagnostic Value of Myocardial Blood Flow and Myocardial Flow Reserve After Cardiac Transplantation
        Robert J.H. Miller, Osamu Manabe, Balaji Tamarappoo, Sean Hayes, John D. Friedman, Piotr J. Slomka, Jignesh Patel, Jon A. Kobashigawa and Daniel S. Berman
        Journal of Nuclear Medicine February 1, 2020, 61 (2) 249-255; DOI: https://doi.org/10.2967/jnumed.119.229625

Neurology

  • Clinical

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      Recovery of Decreased Metabotropic Glutamate Receptor 5 Availability in Abstinent Alcohol-Dependent Patients
      Jenny Ceccarini, Gil Leurquin-Sterk, Cleo Lina Crunelle, Bart de Laat, Guy Bormans, Hendrik Peuskens and Koen Van Laere
      Journal of Nuclear Medicine February 1, 2020, 61 (2) 256-262; DOI: https://doi.org/10.2967/jnumed.119.228825
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      Multimodal 18F-AV-1451 and MRI Findings in Nonfluent Variant of Primary Progressive Aphasia: Possible Insights on Nodal Propagation of Tau Protein Across the Syntactic Network
      Belen Pascual, Quentin Funk, Paolo Zanotti-Fregonara, Neha Pal, Elijah Rockers, Meixiang Yu, Bryan Spann, Gustavo C. Román, Paul E. Schulz, Christof Karmonik, Stanley H. Appel and Joseph C. Masdeu
      Journal of Nuclear Medicine February 1, 2020, 61 (2) 263-269; DOI: https://doi.org/10.2967/jnumed.118.225508

Molecular Imaging

  • Clinical

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      A Clinical Feasibility Study to Image Angiogenesis in Patients with Arteriovenous Malformations Using 68Ga-RGD PET/CT
      Daphne Lobeek, Frédérique C.M. Bouwman, Erik H.J.G. Aarntzen, Janneke D.M. Molkenboer-Kuenen, Uta E. Flucke, Ha-Long Nguyen, Miikka Vikkula, Laurence M. Boon, Willemijn Klein, Peter Laverman, Wim J.G. Oyen, Otto C. Boerman, Samantha Y.A. Terry, Leo J. Schultze Kool and Mark Rijpkema
      Journal of Nuclear Medicine February 1, 2020, 61 (2) 270-275; DOI: https://doi.org/10.2967/jnumed.119.231167

Physics and Instrumentation

  • Clinical

    • Open Access
      Promise of Fully Integrated PET/MRI: Noninvasive Clinical Quantification of Cerebral Glucose Metabolism
      Lalith Kumar Shiyam Sundar, Otto Muzik, Lucas Rischka, Andreas Hahn, Rupert Lanzenberger, Marius Hienert, Eva-Maria Klebermass, Martin Bauer, Ivo Rausch, Ekaterina Pataraia, Tatjana Traub-Weidinger and Thomas Beyer
      Journal of Nuclear Medicine February 1, 2020, 61 (2) 276-284; DOI: https://doi.org/10.2967/jnumed.119.229567
  • Basic

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      Total-Body Dynamic Reconstruction and Parametric Imaging on the uEXPLORER
      Xuezhu Zhang, Zhaoheng Xie, Eric Berg, Martin S. Judenhofer, Weiping Liu, Tianyi Xu, Yu Ding, Yang Lv, Yun Dong, Zilin Deng, Songsong Tang, Hongcheng Shi, Pengcheng Hu, Shuguang Chen, Jun Bao, Hongdi Li, Jian Zhou, Guobao Wang, Simon R. Cherry, Ramsey D. Badawi and Jinyi Qi
      Journal of Nuclear Medicine February 1, 2020, 61 (2) 285-291; DOI: https://doi.org/10.2967/jnumed.119.230565
    • Open Access
      High-Throughput PET/CT Imaging Using a Multiple-Mouse Imaging System
      Hannah E. Greenwood, Zoltan Nyitrai, Gabor Mocsai, Sandor Hobor and Timothy H. Witney
      Journal of Nuclear Medicine February 1, 2020, 61 (2) 292-297; DOI: https://doi.org/10.2967/jnumed.119.228692
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      Denoising of Scintillation Camera Images Using a Deep Convolutional Neural Network: A Monte Carlo Simulation Approach
      David Minarik, Olof Enqvist and Elin Trägårdh
      Journal of Nuclear Medicine February 1, 2020, 61 (2) 298-303; DOI: https://doi.org/10.2967/jnumed.119.226613

Letters to the Editor

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    George de Hevesy in America
    William C. Klingensmith and Joseph R. Osborne
    Journal of Nuclear Medicine February 1, 2020, 61 (2) 304-305; DOI: https://doi.org/10.2967/jnumed.119.233254
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    ABCG2- and ABCB1 Inhibition Using Supratherapeutic Doses of Erlotinib: Clinical Implications in the Treatment of Central Nervous System Metastases
    Eveline A. van de Stadt, Maqsood Yaqub, Idris Bahce and N.H. Hendrikse
    Journal of Nuclear Medicine February 1, 2020, 61 (2) 305; DOI: https://doi.org/10.2967/jnumed.119.235705
  • Open Access
    Pharmacokinetic Imaging with Radiolabeled Molecularly Targeted Anticancer Drugs
    Martin Bauer, Markus Zeitlinger and Oliver Langer
    Journal of Nuclear Medicine February 1, 2020, 61 (2) 306; DOI: https://doi.org/10.2967/jnumed.119.236174

SNMMI Newsline

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    SNMMI Newsline
    Journal of Nuclear Medicine February 1, 2020, 61 (2) 7N-18N;
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    2019 SNMMI Highlights Lecture: Oncology and Therapy, Part 2
    Andrew Scott
    Journal of Nuclear Medicine February 1, 2020, 61 (2) 7N-13N;
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    Newsbriefs
    Journal of Nuclear Medicine February 1, 2020, 61 (2) 13N;
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    ABNM Certification Trends, 1977–2019
    George M. Segall
    Journal of Nuclear Medicine February 1, 2020, 61 (2) 14N;
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    In Memoriam: Conrad Nagle, MD, 1946–2019
    John E. Freitas
    Journal of Nuclear Medicine February 1, 2020, 61 (2) 15N;
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    SNMMI Leadership Update: Paving the Way for Research and Discovery
    Virginia Pappas
    Journal of Nuclear Medicine February 1, 2020, 61 (2) 16N;
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    From the Literature
    Journal of Nuclear Medicine February 1, 2020, 61 (2) 17N-18N;
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In this issue

Journal of Nuclear Medicine: 61 (2)
Journal of Nuclear Medicine
Vol. 61, Issue 2
February 1, 2020
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author

Issue highlights

  • Comparative Prognostic and Diagnostic Value of Myocardial Blood Flow and Myocardial Flow Reserve After Cardiac Transplantation
  • Improving Contrast and Detectability: Imaging with [55Co]Co-DOTATATE in Comparison with [64Cu]Cu-DOTATATE and [68Ga]Ga-DOTATATE
  • The Spatial-Temporal Ordering of Amyloid Pathology and Opportunities for PET Imaging
  • FAP: The Next Billion Dollar Nuclear Theranostics Target?
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  • This Month in JNM
  • Hot Topics
  • The State of the Art
  • Focus on Molecular Imaging
  • Oncology
    • Clinical
      • BRIEF COMMUNICATION
      • BRIEF COMMUNICATION
  • Theranostics
    • Clinical
      • SPECIAL CONTRIBUTION
    • Basic
      • FEATURED BASIC SCIENCE ARTICLE
  • Radionuclide Therapy
    • Basic
  • Cardiovascular
    • Clinical
      • FEATURED ARTICLE OF THE MONTH
  • Neurology
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  • Physics and Instrumentation
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  • Letters to the Editor
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  • Long-Term Follow-up and Outcomes of Retreatment in an Expanded 50-Patient Single-Center Phase II Prospective Trial of 177Lu-PSMA-617 Theranostics in Metastatic Castration-Resistant Prostate Cancer
  • First-in-Human Assessment of 11C-LSN3172176, an M1 Muscarinic Acetylcholine Receptor PET Radiotracer
  • Impact of 68Ga-PSMA-11 PET/CT on Staging and Management of Prostate Cancer Patients in Various Clinical Settings: A Prospective Single-Center Study
  • Tau PET imaging with 18F-PI-2620 in Patients with Alzheimer Disease and Healthy Controls: A First-in-Humans Study
  • Radiation Dosimetry in 177Lu-PSMA-617 Therapy Using a Single Posttreatment SPECT/CT Scan: A Novel Methodology to Generate Time- and Tissue-Specific Dose Factors
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