Journal of Nuclear Medicine: 58 (3)

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March 1, 2017; Volume 58,Issue 3

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine March 1, 2017, 58 (3) 8A;

Hot Topics

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Machine Learning Will Change Medicine
Michael Forsting

Journal of Nuclear Medicine March 1, 2017, 58 (3) 357-358; DOI: https://doi.org/10.2967/jnumed.117.190397

Focus on Molecular Imaging

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Molecular Imaging of Vulnerable Coronary Plaque: A Pathophysiologic Perspective
Sandeep Krishnan, Yuka Otaki, Mhairi Doris, Leandro Slipczuk, Yoav Arnson, Mathieu Rubeaux, Damini Dey, Piotr Slomka, Daniel S. Berman and Balaji Tamarappoo

Journal of Nuclear Medicine March 1, 2017, 58 (3) 359-364; DOI: https://doi.org/10.2967/jnumed.116.187906

Invited Perspectives

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Radiomics in PET/CT: More Than Meets the Eye?
Mathieu Hatt, Florent Tixier, Dimitris Visvikis and Catherine Cheze Le Rest

Journal of Nuclear Medicine March 1, 2017, 58 (3) 365-366; DOI: https://doi.org/10.2967/jnumed.116.184655

Oncology

Basic
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  ¹⁸F-5-Fluoroaminosuberic Acid as a Potential Tracer to Gauge Oxidative Stress in Breast Cancer Models
  Hua Yang, Silvia Jenni, Milena Colovic, Helen Merkens, Carlee Poleschuk, Isabel Rodrigo, Qing Miao, Bruce F. Johnson, Michael J. Rishel, Vesna Sossi, Jack M. Webster, François Bénard and Paul Schaffer
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 367-373; DOI: https://doi.org/10.2967/jnumed.116.180661
Translational
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  Human Biodistribution and Radiation Dosimetry of ¹⁸F-Clofarabine, a PET Probe Targeting the Deoxyribonucleoside Salvage Pathway
  Martin J. Barrio, Claudio Spick, Caius G. Radu, Michael Lassmann, Uta Eberlein, Martin Allen-Auerbach, Christiaan Schiepers, Roger Slavik, Johannes Czernin and Ken Herrmann
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 374-378; DOI: https://doi.org/10.2967/jnumed.116.182394
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  Safety, Dosimetry, and Tumor Detection Ability of ⁶⁸Ga-NOTA-AE105: First-in-Human Study of a Novel Radioligand for uPAR PET Imaging
  Dorthe Skovgaard, Morten Persson, Malene Brandt-Larsen, Camilla Christensen, Jacob Madsen, Thomas Levin Klausen, Søren Holm, Flemming Littrup Andersen, Annika Loft, Anne Kiil Berthelsen, Helle Pappot, Klaus Brasso, Niels Kroman, Liselotte Højgaard and Andreas Kjaer
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 379-386; DOI: https://doi.org/10.2967/jnumed.116.178970
- FEATURED TRANSLATIONAL SCIENCE ARTICLE
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    Understanding Changes in Tumor Texture Indices in PET: A Comparison Between Visual Assessment and Index Values in Simulated and Patient Data
    Fanny Orlhac, Christophe Nioche, Michaël Soussan and Irène Buvat
    
    Journal of Nuclear Medicine March 1, 2017, 58 (3) 387-392; DOI: https://doi.org/10.2967/jnumed.116.181859
Clinical
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  Repeatability of ¹⁸F-FLT PET in a Multicenter Study of Patients with High-Grade Glioma
  Martin A. Lodge, Matthias Holdhoff, Jeffrey P. Leal, Asim K. Bag, L. Burt Nabors, Akiva Mintz, Glenn J. Lesser, David A. Mankoff, Arati S. Desai, James M. Mountz, Frank S. Lieberman, Joy D. Fisher, Serena Desideri, Xiaobu Ye, Stuart A. Grossman, David Schiff and Richard L. Wahl
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 393-398; DOI: https://doi.org/10.2967/jnumed.116.178434
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  Quantitative Accuracy and Lesion Detectability of Low-Dose ¹⁸F-FDG PET for Lung Cancer Screening
  Joshua D. Schaefferkoetter, Jianhua Yan, Therese Sjöholm, David W. Townsend, Maurizio Conti, John Kit Chung Tam, Ross A. Soo and Ivan Tham
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 399-405; DOI: https://doi.org/10.2967/jnumed.116.177592
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  Reliability of PET/CT Shape and Heterogeneity Features in Functional and Morphologic Components of Non–Small Cell Lung Cancer Tumors: A Repeatability Analysis in a Prospective Multicenter Cohort
  Marie-Charlotte Desseroit, Florent Tixier, Wolfgang A. Weber, Barry A. Siegel, Catherine Cheze Le Rest, Dimitris Visvikis and Mathieu Hatt
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 406-411; DOI: https://doi.org/10.2967/jnumed.116.180919
- FEATURED CLINICAL INVESTIGATION ARTICLE
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    Impact of ¹⁸F-Fluciclovine PET on Target Volume Definition for Postprostatectomy Salvage Radiotherapy: Initial Findings from a Randomized Trial
    Ashesh B. Jani, Eduard Schreibmann, Peter J. Rossi, Joseph Shelton, Karen Godette, Peter Nieh, Viraj A. Master, Omer Kucuk, Mark Goodman, Raghuveer Halkar, Sherrie Cooper, Zhengjia Chen and David M. Schuster
    
    Journal of Nuclear Medicine March 1, 2017, 58 (3) 412-418; DOI: https://doi.org/10.2967/jnumed.116.176057
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  Comparison of ¹¹C-Methionine and ¹⁸F-FDG PET/CT for Staging and Follow-up of Pediatric Lymphoma
  Sue C. Kaste, Scott E. Snyder, Monika L. Metzger, John T. Sandlund, Scott C. Howard, Matthew Krasin and Barry L. Shulkin
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 419-424; DOI: https://doi.org/10.2967/jnumed.116.178640

Theranostics

Basic
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  Preclinical Evaluation of ¹⁸F-PSMA-1007, a New Prostate-Specific Membrane Antigen Ligand for Prostate Cancer Imaging
  Jens Cardinale, Martin Schäfer, Martina Benešová, Ulrike Bauder-Wüst, Karin Leotta, Matthias Eder, Oliver C. Neels, Uwe Haberkorn, Frederik L. Giesel and Klaus Kopka
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 425-431; DOI: https://doi.org/10.2967/jnumed.116.181768
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  Optimization of Labeling PSMA^HBED with Ethanol-Postprocessed ⁶⁸Ga and Its Quality Control Systems
  Elisabeth Eppard, Tatjana Homann, Ana de la Fuente, Markus Essler and Frank Rösch
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 432-437; DOI: https://doi.org/10.2967/jnumed.116.177634
Clinical
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  ⁶⁸Ga-PSMA-11 PET as a Gatekeeper for the Treatment of Metastatic Prostate Cancer with ²²³Ra: Proof of Concept
  Hojjat Ahmadzadehfar, Kambiz Azgomi, Stefan Hauser, Xiao Wei, Anna Yordanova, Florian C. Gaertner, Stefan Kürpig, Holger Strunk and Markus Essler
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 438-444; DOI: https://doi.org/10.2967/jnumed.116.178533
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  Radiation Dosimetry for ¹⁷⁷Lu-PSMA I&T in Metastatic Castration-Resistant Prostate Cancer: Absorbed Dose in Normal Organs and Tumor Lesions
  Shozo Okamoto, Anne Thieme, Jakob Allmann, Calogero D’Alessandria, Tobias Maurer, Margitta Retz, Robert Tauber, Matthias M. Heck, Hans-Juergen Wester, Nagara Tamaki, Wolfgang P. Fendler, Ken Herrmann, Christian H. Pfob, Klemens Scheidhauer, Markus Schwaiger, Sibylle Ziegler and Matthias Eiber
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 445-450; DOI: https://doi.org/10.2967/jnumed.116.178483
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  Head-to-Head Comparison of ⁶⁴Cu-DOTATATE and ⁶⁸Ga-DOTATOC PET/CT: A Prospective Study of 59 Patients with Neuroendocrine Tumors
  Camilla B. Johnbeck, Ulrich Knigge, Annika Loft, Anne K. Berthelsen, Jann Mortensen, Peter Oturai, Seppo W. Langer, Dennis R. Elema and Andreas Kjaer
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 451-457; DOI: https://doi.org/10.2967/jnumed.116.180430

Neurology

Basic
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  Characterization of ¹¹C-GSK1482160 for Targeting the P2X7 Receptor as a Biomarker for Neuroinflammation
  Paul R. Territo, Jill A. Meyer, Jonathan S. Peters, Amanda A. Riley, Brian P. McCarthy, Mingzhang Gao, Min Wang, Mark A. Green, Qi-Huang Zheng and Gary D. Hutchins
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 458-465; DOI: https://doi.org/10.2967/jnumed.116.181354
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  Preclinical Evaluation and Quantification of ¹⁸F-Fluoroethyl and ¹⁸F-Fluoropropyl Analogs of SCH442416 as Radioligands for PET Imaging of the Adenosine A_2A Receptor in Rat Brain
  Shivashankar Khanapur, Aren van Waarde, Rudi A.J.O. Dierckx, Philip H. Elsinga and Michel J.B. Koole
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 466-472; DOI: https://doi.org/10.2967/jnumed.116.178103
Translational
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  Biodistribution and Radiation Dosimetry of ¹¹C-Nicotine from Whole-Body PET Imaging in Humans
  Pradeep K. Garg, Stephen J. Lokitz, Rachid Nazih and Sudha Garg
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 473-478; DOI: https://doi.org/10.2967/jnumed.116.180059
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  Parametric Methods for Dynamic ¹¹C-Phenytoin PET Studies
  Syahir Mansor, Maqsood Yaqub, Ronald Boellaard, Femke E. Froklage, Anke de Vries, Esther D.M. Bakker, Rob A. Voskuyl, Jonas Eriksson, Lothar A. Schwarte, Joost Verbeek, Albert D. Windhorst and Adriaan A. Lammertsma
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 479-483; DOI: https://doi.org/10.2967/jnumed.116.178707
Clinical
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  Pharmacokinetic Evaluation of the Tau PET Radiotracer ¹⁸F-T807 (¹⁸F-AV-1451) in Human Subjects
  Dustin W. Wooten, Nicolas J. Guehl, Eline E. Verwer, Timothy M. Shoup, Daniel L. Yokell, Nevena Zubcevik, Neil Vasdev, Ross D. Zafonte, Keith A. Johnson, Georges El Fakhri and Marc D. Normandin
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 484-491; DOI: https://doi.org/10.2967/jnumed.115.170910
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  Brain ¹⁸F-FDG PET Metabolic Abnormalities in Patients with Long-Lasting Macrophagic Myofascitis
  Axel Van Der Gucht, Mehdi Aoun Sebaiti, Eric Guedj, Jessie Aouizerate, Sabrina Yara, Romain K. Gherardi, Eva Evangelista, Julia Chalaye, Anne-Ségolène Cottereau, Antoine Verger, Anne-Catherine Bachoud-Levi, Mukedaisi Abulizi, Emmanuel Itti and François-Jérôme Authier
  
  Journal of Nuclear Medicine March 1, 2017, 58 (3) 492-498; DOI: https://doi.org/10.2967/jnumed.114.151878

Cardiology

Basic
- FEATURED ARTICLE OF THE MONTH
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    Imaging the Cytokine Receptor CXCR4 in Atherosclerotic Plaques with the Radiotracer ⁶⁸Ga-Pentixafor for PET
    Fabien Hyafil, Jaroslav Pelisek, Iina Laitinen, Margret Schottelius, Miriam Mohring, Yvonne Döring, Emiel P.C. van der Vorst, Michael Kallmayer, Katja Steiger, Andreas Poschenrieder, Johannes Notni, Johannes Fischer, Christine Baumgartner, Christoph Rischpler, Stephan G. Nekolla, Christian Weber, Hans-Henning Eckstein, Hans-Jürgen Wester and Markus Schwaiger
    
    Journal of Nuclear Medicine March 1, 2017, 58 (3) 499-506; DOI: https://doi.org/10.2967/jnumed.116.179663

Imaging/Infection

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Evaluation of Spleen Glucose Metabolism Using ¹⁸F-FDG PET/CT in Patients with Febrile Autoimmune Disease
Sung Soo Ahn, Sang Hyun Hwang, Seung Min Jung, Sang-Won Lee, Yong-Beom Park, Mijin Yun and Jason Jungsik Song

Journal of Nuclear Medicine March 1, 2017, 58 (3) 507-513; DOI: https://doi.org/10.2967/jnumed.116.180729

Brief Communications

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Fission-Produced ⁹⁹Mo Without a Nuclear Reactor
Amanda J. Youker, Sergey D. Chemerisov, Peter Tkac, Michael Kalensky, Thad A. Heltemes, David A. Rotsch, George F. Vandegrift, John F. Krebs, Vakho Makarashvili and Dominique C. Stepinski

Journal of Nuclear Medicine March 1, 2017, 58 (3) 514-517; DOI: https://doi.org/10.2967/jnumed.116.181040

Letters to the Editor

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Variation in Maximum Counting Rates During Myocardial Blood Flow Quantification Using ⁸²Rb PET
Joris D. van Dijk, Pieter L. Jager, Jochen A.C. van Osch and Jorn A. van Dalen

Journal of Nuclear Medicine March 1, 2017, 58 (3) 518-519; DOI: https://doi.org/10.2967/jnumed.116.187757
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Reply: Variation in Maximum Counting Rates During Myocardial Blood Flow Quantification Using ⁸²Rb PET
Jennifer M. Renaud, Jonathan B. Moody and Robert A. deKemp

Journal of Nuclear Medicine March 1, 2017, 58 (3) 519-520; DOI: https://doi.org/10.2967/jnumed.116.188086
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Regarding “Subjecting Radiologic Imaging to the Linear No-Threshold Hypothesis: A Non Sequitur of Non-Trivial Proportion”
Alan Fellman

Journal of Nuclear Medicine March 1, 2017, 58 (3) 520; DOI: https://doi.org/10.2967/jnumed.117.189787
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Regarding “Subjecting Radiologic Imaging to the Linear No-Threshold Hypothesis: A Non Sequitur of Non-Trivial Proportion”
Stephen K. Gerard

Journal of Nuclear Medicine March 1, 2017, 58 (3) 520-521; DOI: https://doi.org/10.2967/jnumed.117.189795
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Regarding “Subjecting Radiologic Imaging to the Linear No-Threshold Hypothesis: A Non Sequitur of Non-Trivial Proportion”
Joseph John Bevelacqua

Journal of Nuclear Medicine March 1, 2017, 58 (3) 521-522; DOI: https://doi.org/10.2967/jnumed.117.189803
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Regarding “Subjecting Radiologic Imaging to the Linear No-Threshold Hypothesis: A Non Sequitur of Non-Trivial Proportion”
Christopher Feltham

Journal of Nuclear Medicine March 1, 2017, 58 (3) 522; DOI: https://doi.org/10.2967/jnumed.117.189852
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Regarding “Subjecting Radiologic Imaging to the Linear No-Threshold Hypothesis: A Non Sequitur of Non-Trivial Proportion”
Ludwig E. Feinendegen

Journal of Nuclear Medicine March 1, 2017, 58 (3) 522; DOI: https://doi.org/10.2967/jnumed.117.190330

SNMMI Newsline

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ABNM Introduces CertLink
George Segall

Journal of Nuclear Medicine March 1, 2017, 58 (3) 9N;
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Alavi Recognized with International Awards
Journal of Nuclear Medicine March 1, 2017, 58 (3) 10N;
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In Memoriam: Frederick J. Bonte, MD 1922–2016
Journal of Nuclear Medicine March 1, 2017, 58 (3) 11N;
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SNMMI Leadership Update: Preparing the Next Generation of Nuclear Medicine Professionals
Sally W. Schwarz

Journal of Nuclear Medicine March 1, 2017, 58 (3) 12N;
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Newsbriefs
Journal of Nuclear Medicine March 1, 2017, 58 (3) 13N-15N;
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From the Literature
Journal of Nuclear Medicine March 1, 2017, 58 (3) 15N-20N;

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