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OtherClinical Investigations

18F-Fluoro-l-Thymidine and 11C-Methylmethionine as Markers of Increased Transport and Proliferation in Brain Tumors

Andreas H. Jacobs, Anne Thomas, Lutz W. Kracht, Huongfeng Li, Claus Dittmar, Guido Garlip, Norbert Galldiks, Johannes C. Klein, Jan Sobesky, Rüdiger Hilker, Stefan Vollmar, Karl Herholz, Klaus Wienhard and Wolf-Dieter Heiss
Journal of Nuclear Medicine December 2005, 46 (12) 1948-1958;
Andreas H. Jacobs
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Anne Thomas
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Lutz W. Kracht
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Huongfeng Li
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Claus Dittmar
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Guido Garlip
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Norbert Galldiks
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Johannes C. Klein
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Jan Sobesky
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Rüdiger Hilker
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Stefan Vollmar
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Karl Herholz
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Klaus Wienhard
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Wolf-Dieter Heiss
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Article Information

vol. 46 no. 12 1948-1958
PubMed 
16330557

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Published online December 5, 2005.

Copyright & Usage 
THE JOURNAL OF NUCLEAR MEDICINE

Author Information

  1. Andreas H. Jacobs, MD1,2,3,
  2. Anne Thomas, MD1,2,
  3. Lutz W. Kracht, MD1,
  4. Huongfeng Li, PhD1,
  5. Claus Dittmar, PhD1,
  6. Guido Garlip, MD1,
  7. Norbert Galldiks, MD1,
  8. Johannes C. Klein, MD1,
  9. Jan Sobesky, MD1,2,
  10. Rüdiger Hilker, MD1,2,
  11. Stefan Vollmar, PhD1,2,
  12. Karl Herholz, MD1,2,
  13. Klaus Wienhard, PhD1 and
  14. Wolf-Dieter Heiss, MD1,2,3
  1. 1Max Planck Institute for Neurological Research, Cologne, Germany
  2. 2Department of Neurology, University of Cologne, Cologne, Germany
  3. 3Center for Molecular Medicine, University of Cologne, Cologne, Germany
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Journal of Nuclear Medicine: 46 (12)
Journal of Nuclear Medicine
Vol. 46, Issue 12
December 1, 2005
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18F-Fluoro-l-Thymidine and 11C-Methylmethionine as Markers of Increased Transport and Proliferation in Brain Tumors
Andreas H. Jacobs, Anne Thomas, Lutz W. Kracht, Huongfeng Li, Claus Dittmar, Guido Garlip, Norbert Galldiks, Johannes C. Klein, Jan Sobesky, Rüdiger Hilker, Stefan Vollmar, Karl Herholz, Klaus Wienhard, Wolf-Dieter Heiss
Journal of Nuclear Medicine Dec 2005, 46 (12) 1948-1958;

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18F-Fluoro-l-Thymidine and 11C-Methylmethionine as Markers of Increased Transport and Proliferation in Brain Tumors
Andreas H. Jacobs, Anne Thomas, Lutz W. Kracht, Huongfeng Li, Claus Dittmar, Guido Garlip, Norbert Galldiks, Johannes C. Klein, Jan Sobesky, Rüdiger Hilker, Stefan Vollmar, Karl Herholz, Klaus Wienhard, Wolf-Dieter Heiss
Journal of Nuclear Medicine Dec 2005, 46 (12) 1948-1958;
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  • Correlation of MRI-Derived Apparent Diffusion Coefficients in Newly Diagnosed Gliomas with [18F]-Fluoro-L-Dopa PET: What Are We Really Measuring with Minimum ADC?
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  • Tumor 3'-Deoxy-3'-18F-Fluorothymidine (18F-FLT) Uptake by PET Correlates with Thymidine Kinase 1 Expression: Static and Kinetic Analysis of 18F-FLT PET Studies in Lung Tumors
  • Correlation of 6-18F-Fluoro-L-Dopa PET Uptake with Proliferation and Tumor Grade in Newly Diagnosed and Recurrent Gliomas
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  • Switching on the Lights for Real-Time Multimodality Tumor Neuroimaging: The Integrated Positron-Emission Tomography/MR Imaging System
  • Kinetic Modeling of 3'-Deoxy-3'-18F-Fluorothymidine for Quantitative Cell Proliferation Imaging in Subcutaneous Tumor Models in Mice
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  • Glioma Proliferation as Assessed by 3'-Fluoro-3'-Deoxy-L-Thymidine Positron Emission Tomography in Patients with Newly Diagnosed High-Grade Glioma
  • Dynamic Small-Animal PET Imaging of Tumor Proliferation with 3'-Deoxy-3'-18F-Fluorothymidine in a Genetically Engineered Mouse Model of High-Grade Gliomas
  • Predicting Treatment Response of Malignant Gliomas to Bevacizumab and Irinotecan by Imaging Proliferation With [18F] Fluorothymidine Positron Emission Tomography: A Pilot Study
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