Article Figures & Data
Figures
- FIGURE 1.
PET performed with 18F-FDG (A) and Met (B) on a 32-y-old man with an AA in the left frontorolandic cortical area. Uptake of 18F-FDG in tumor was equivalent to that in cortical gray matter. Uptake of Met was higher in tumor than in cortex, allowing definition of a target for biopsy. When PET images obtained with the 2 tracers were coregistered, the focus of highest Met uptake corresponded to the unique focus of 18F-FDG uptake within the tumor (crosses).
- FIGURE 2.
PET performed with 18F-FDG (A) and Met (B) on a 62-y-old woman with a GB in the right prerolandic cortical area. Uptake of 18F-FDG was reduced in the tumor area except for 1 spot of uptake equivalent to that in the surrounding gray matter. Uptake of Met was higher in tumor than in cortex, allowing definition of a target for biopsy. When PET images obtained with the 2 tracers were coregistered, the highest focus of Met uptake corresponded to the hot spot of 18F-FDG (crosses).
- FIGURE 3.
PET performed with 18F-FDG (A) and Met (B) on a 74-y-old man with a GB in the right basal ganglia. Uptake of 18F-FDG was higher in tumor than in surrounding gray matter and allowed definition of a target for biopsy. Uptake of Met was also higher in tumor than in surrounding gray matter, and zones of highest uptake of both tracers corresponded on coregistered images (crosses).
- FIGURE 4.
MRI (A) and PET performed with 18F-FDG (B) and Met (C) on a 57-y-old woman with an infiltrating AA in the left basal ganglia and subcortical frontal region. Uptake of 18F-FDG was higher in tumor than in surrounding gray matter and allowed definition of a target for biopsy. Uptake of Met was also higher in tumor than in surrounding gray matter. Coregistration of PET images showed that Met uptake was more extended than 18F-FDG uptake but that zones of highest uptake corresponded (crosses).
Tables
Diagnosis 18F-FDG-defined target (FDGt > FDGgm) Met-defined target FDGt = FDGgm FDGt < FDGgm GB 7 3 — AA 6 5 1 LGG 1 5 4 Total 14 13 5 FDGt = 18F-FDG uptake in tumor; FDGgm = 18F-FDG uptake in surrounding gray matter.
Diagnosis Met(+) trajectories Met(−) trajectories (FDGt < FDGgm) FDGt > FDGgm FDGt = FDGgm FDGt < FDGgm GB 11 7 — — AA 10 9 2 — LGG 1 6 15 — Nondiagnostic — — — 9 Total 22 22 17 9 FDGt = 18F-FDG uptake in tumor; FDGgm = 18F-FDG uptake in surrounding gray matter.
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