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Journal of Nuclear Medicine Vol. 46 No. 4 608-613
© 2005 by Society of Nuclear Medicine


Brief Communication

Radiation Exposure of Patients Undergoing Whole-Body Dual-Modality 18F-FDG PET/CT Examinations

Gunnar Brix, PhD1, Ursula Lechel, MS1, Gerhard Glatting, PhD2, Sibylle I. Ziegler, PhD3, Wolfgang Münzing, PhD4, Stefan P. Müller, MD5 and Thomas Beyer, PhD5

1 Division of Medical Radiation Hygiene and Dosimetry, Federal Office for Radiation Protection, Neuherberg, Germany
2 Department of Nuclear Medicine, University of Ulm, Ulm, Germany
3 Department of Nuclear Medicine, Technical University Munich, Munich, Germany
4 Department of Nuclear Medicine, University of Munich, Munich, Germany
5 Department of Nuclear Medicine, University Hospital Essen, Essen, Germany

We investigated radiation exposure of patients undergoing whole-body 18F-FDG PET/CT examinations at 4 hospitals equipped with different tomographs. Methods: Patient doses were estimated by using established dose coefficients for 18F-FDG and from thermoluminescent measurements performed on an anthropomorphic whole-body phantom. Results: The most relevant difference between the protocols examined was the incorporation of CT as part of the combined PET/CT examination: Separate low-dose CT scans were acquired at 2 hospitals for attenuation correction of emission data in addition to a contrast-enhanced CT scan for diagnostic evaluation, whereas, at the other sites, contrast-enhanced CT scans were used for both purposes. Nevertheless, the effective dose per PET/CT examination was similar, about 25 mSv. Conclusion: The dosimetric concepts presented in this study provide a valuable tool for the optimization of whole-body 18F-FDG PET/CT protocols. Further reduction of patient exposure can be achieved by modifications to the existing hardware and software of PET/CT systems.

Key Words: PET/CT • patient exposure • dosimetry • dose reduction


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