Journal of Nuclear Medicine: 64 (6)

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June 1, 2023; Volume 64,Issue 6

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine June 1, 2023, 64 (6) 10A;

Message from the SNMMI President

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Transforming the Science and Practice of Nuclear Medicine
Munir Ghesani

Journal of Nuclear Medicine June 1, 2023, 64 (6) 829-830;

Discussions with Leaders

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Defining Myeloma and Advancing Treatment Options
S. Vincent Rajkumar and Lale Kostakoglu

Journal of Nuclear Medicine June 1, 2023, 64 (6) 831-834; DOI: https://doi.org/10.2967/jnumed.123.265877

State of the Art

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¹⁸F-Labeled Somatostatin Analogs as PET Tracers for the Somatostatin Receptor: Ready for Clinical Use
Hannes Leupe, Stephen Ahenkorah, Jeroen Dekervel, Marcus Unterrainer, Eric Van Cutsem, Chris Verslype, Frederik Cleeren and Christophe M. Deroose

Journal of Nuclear Medicine June 1, 2023, 64 (6) 835-841; DOI: https://doi.org/10.2967/jnumed.123.265622

Continuing Education

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¹⁸F-FDG PET/CT in the Management of Osteosarcoma
Chiwoo Oh, Michael W. Bishop, Steve Y. Cho, Hyung-Jun Im and Barry L. Shulkin

Journal of Nuclear Medicine June 1, 2023, 64 (6) 842-851; DOI: https://doi.org/10.2967/jnumed.123.265592

Oncology

Clinical
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  Distinguishing Progression from Pseudoprogression in Glioblastoma Using ¹⁸F-Fluciclovine PET
  Ali Nabavizadeh, Stephen J. Bagley, Robert K. Doot, Jeffrey B. Ware, Anthony J. Young, Satyam Ghodasara, Chao Zhao, Hannah Anderson, Erin Schubert, Erica L. Carpenter, Jacob Till, Fraser Henderson, Austin R. Pantel, H. Isaac Chen, John Y.K. Lee, Nduka M. Amankulor, Donald M. O’Rourke, Arati Desai, MacLean P. Nasrallah and Steven Brem
  
  Journal of Nuclear Medicine June 1, 2023, 64 (6) 852-858; DOI: https://doi.org/10.2967/jnumed.122.264812
- BRIEF COMMUNICATION
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    Preliminary Clinical Experience with Cholecystokinin-2 Receptor PET/CT Using the ⁶⁸Ga-Labeled Minigastrin Analog DOTA-MGS5 in Patients with Medullary Thyroid Cancer
    Elisabeth von Guggenberg, Christian Uprimny, Maximilian Klinger, Boris Warwitz, Anna Sviridenko, Steffen Bayerschmidt, Gianpaolo di Santo and Irene J. Virgolini
    
    Journal of Nuclear Medicine June 1, 2023, 64 (6) 859-862; DOI: https://doi.org/10.2967/jnumed.122.264977
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  Consecutive Prostate-Specific Membrane Antigen (PSMA) and Antigen Receptor (AR) PET Imaging Shows Positive Correlation with AR and PSMA Protein Expression in Primary Hormone-Naïve Prostate Cancer
  Valentin al Jalali, Gabriel Wasinger, Sazan Rasul, Bernhard Grubmüller, Beatrix Wulkersdorfer, Theresa Balber, Markus Mitterhauser, Judit Simon, Marcus Hacker, Shahrokh Shariat, Gerda Egger and Markus Zeitlinger
  
  Journal of Nuclear Medicine June 1, 2023, 64 (6) 863-868; DOI: https://doi.org/10.2967/jnumed.122.264981

Radionuclide Therapy

Clinical
- FEATURED CLINICAL INVESTIGATION ARTICLE
  - Open Access
    Developing a Patient-Reported Outcome Measure for Radionuclide Therapy for Prostate Cancer
    Lisa M. Gudenkauf, Melody N. Chavez, Melinda Leigh Maconi, Carley Geiss, Ameen Seyedroudbari, Pan Thin, Aasha I. Hoogland, Kathleen Nguyen, Vishnu Murthy, Wesley R. Armstrong, Khaled Komrokji, Laura B. Oswald, Heather S.L. Jim, Ghassan El-Haddad, Wolfgang P. Fendler, Ken Herrmann, David Cella, Johannes Czernin, Michael S. Hofman, Adam P. Dicker, Jeremie Calais, Scott T. Tagawa and Brian D. Gonzalez
    
    Journal of Nuclear Medicine June 1, 2023, 64 (6) 869-872; DOI: https://doi.org/10.2967/jnumed.122.264946
Basic
- Open Access
  Signaling Network Response to α-Particle–Targeted Therapy with the ²²⁵Ac-Labeled Minigastrin Analog ²²⁵Ac-PP-F11N Reveals the Radiosensitizing Potential of Histone Deacetylase Inhibitors
  Yun Qin, Stefan Imobersteg, Stephan Frank, Alain Blanc, Tanja Chiorazzo, Philipp Berger, Roger Schibli, Martin P. Béhé and Michal Grzmil
  
  Journal of Nuclear Medicine June 1, 2023, 64 (6) 873-879; DOI: https://doi.org/10.2967/jnumed.122.264597

Theranostics

Clinical
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  Evaluation of Hepatotoxicity from Peptide Receptor Radionuclide Therapy in Patients with Gastroenteropancreatic Neuroendocrine Tumors and a Very High Liver Tumor Burden
  Denise A. Gococo-Benore, Justin Kuhlman, Ephraim E. Parent, Akash Sharma, Joseph Accurso, Ming Yang, Ayse Tuba Kendi, Geoff Johnson, Mohamad Bassam Sonbol, Timothy Hobday, Thorvardur R. Halfdanarson and Jason Starr
  
  Journal of Nuclear Medicine June 1, 2023, 64 (6) 880-884; DOI: https://doi.org/10.2967/jnumed.122.264533
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  Efficacy and Safety of ¹²⁴I-MIBG Dosimetry-Guided High-Activity ¹³¹I-MIBG Therapy of Advanced Pheochromocytoma or Neuroblastoma
  Ines Maric, Manuel Weber, Andre Prochnow, Jochen Schmitz, Nicole Unger, Benedikt M. Schaarschmidt, Thorsten D. Poeppel, Christoph Rischpler, Andreas Bockisch, Ken Herrmann, Walter Jentzen and Wolfgang P. Fendler
  
  Journal of Nuclear Medicine June 1, 2023, 64 (6) 885-891; DOI: https://doi.org/10.2967/jnumed.122.264775
- BRIEF COMMUNICATION
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    [¹⁷⁷Lu]Lu-PSMA Therapy as an Individual Treatment Approach for Patients with High-Grade Glioma: Dosimetry Results and Critical Statement
    Josefine Graef, Stephanie Bluemel, Winfried Brenner, Holger Amthauer, Peter Truckenmueller, David Kaul, Peter Vajkoczy, Julia S. Onken and Christian Furth
    
    Journal of Nuclear Medicine June 1, 2023, 64 (6) 892-895; DOI: https://doi.org/10.2967/jnumed.122.264850
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  Prognostic Role of ⁶⁸Ga-PSMA11 PET–Based Response in Patients with Prostate Cancer Undergoing Taxane-Based Chemotherapy
  Lukas Lunger, Maythinee Chantadisai, Amir Karimzadeh, Isabel Rauscher, Calogero D’Alessandria, Benedikt Feuerecker, Thomas Langbein, Robert Tauber, Stefan Schiele, Wolfgang Weber and Matthias Eiber
  
  Journal of Nuclear Medicine June 1, 2023, 64 (6) 896-901; DOI: https://doi.org/10.2967/jnumed.122.264962
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  ⁶⁸Ga-PSMA PET/CT–Based Atlas for Prostate Bed Recurrence After Radical Prostatectomy: Clinical Implications for Salvage Radiation Therapy Contouring Guidelines
  Ida Sonni, Alan Dal Pra, Dylan P. O’Connell, Zachary Ells, Matthias Benz, Kathleen Nguyen, Stephanie M. Yoon, Jie Deng, Clayton Smith, Tristan Grogan, Nickolas G. Nickols, Minsong Cao, Amar U. Kishan and Jeremie Calais
  
  Journal of Nuclear Medicine June 1, 2023, 64 (6) 902-909; DOI: https://doi.org/10.2967/jnumed.122.265025
- Open Access
  Prostate-Specific Membrane Antigen Expression on PET/CT in Patients with Metastatic Castration-Resistant Prostate Cancer: A Retrospective Observational Study
  Letizia Calderoni, Elisa Maietti, Andrea Farolfi, Riccardo Mei, Karly S. Louie, Michael Groaning and Stefano Fanti
  
  Journal of Nuclear Medicine June 1, 2023, 64 (6) 910-917; DOI: https://doi.org/10.2967/jnumed.122.264964
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  An Analysis of the Distribution of PSMA PET/CT–Positive Lymph Nodes and Their Coverage by Different Elective Nodal Radiation Volumes in Postoperative Prostate Cancer Patients
  Christian Trapp, Dmytro Oliinyk, Paul Rogowski, Rieke von Bestenbostel, Ute Ganswindt, Minglun Li, Chukwuka Eze, Peter Bartenstein, Leonie Beyer, Harun Ilhan, Gabriel Sheikh, Lena Unterrainer, Christian Stief, Thilo Westhofen, Wolfgang G. Kunz, Marcus Unterrainer, Claus Belka and Nina-Sophie Schmidt-Hegemann
  
  Journal of Nuclear Medicine June 1, 2023, 64 (6) 918-923; DOI: https://doi.org/10.2967/jnumed.122.265159
Basic
- Open Access
  Cure of Disseminated Human Lymphoma with [²²⁵Ac]Ac-Ofatumumab in a Preclinical Model
  Mark S. Longtine, Kyuhwan Shim, Mark J. Hoegger, Nadia Benabdallah, Diane S. Abou, Daniel L.J. Thorek and Richard L. Wahl
  
  Journal of Nuclear Medicine June 1, 2023, 64 (6) 924-931; DOI: https://doi.org/10.2967/jnumed.122.265167

Cardiovascular

Clinical
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  Left Ventricular Strain from Myocardial Perfusion PET Imaging: Method Development and Comparison to 2-Dimensional Echocardiography
  Jingwen Huang, Adam J. Mitchell, Ernest V. Garcia, C. David Cooke, Russell Folks, Maria Pernetz, Abhinav Goyal, Marina Piccinelli and Jonathon A. Nye
  
  Journal of Nuclear Medicine June 1, 2023, 64 (6) 932-939; DOI: https://doi.org/10.2967/jnumed.122.264516

Pulmonary

Basic
- FEATURED ARTICLE OF THE MONTH
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    Radiolabeled GPVI-Fc for PET Imaging of Multiple Extracellular Matrix Fibers: A New Look into Pulmonary Fibrosis Progression
    Simon Isser, Andreas Maurer, Gerald Reischl, Martin Schaller, Irene Gonzalez-Menendez, Leticia Quintanilla-Martinez, Meinrad Gawaz, Bernd J. Pichler and Nicolas Beziere
    
    Journal of Nuclear Medicine June 1, 2023, 64 (6) 940-945; DOI: https://doi.org/10.2967/jnumed.122.264552

Radiobiology/Dosimetry

Clinical
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  Radioimmunoscintigraphy and Pretreatment Dosimetry of ¹³¹I-Omburtamab for Planning Treatment of Leptomeningeal Disease
  Neeta Pandit-Taskar, Milan Grkovski, Pat B. Zanzonico, Keith S. Pentlow, Shakeel Modak, Kim Kramer and John L. Humm
  
  Journal of Nuclear Medicine June 1, 2023, 64 (6) 946-950; DOI: https://doi.org/10.2967/jnumed.122.265131

AI/Advanced Image Analysis

Clinical
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  An Investigation of Lesion Detection Accuracy for Artificial Intelligence–Based Denoising of Low-Dose ⁶⁴Cu-DOTATATE PET Imaging in Patients with Neuroendocrine Neoplasms
  Mathias Loft, Claes N. Ladefoged, Camilla B. Johnbeck, Esben A. Carlsen, Peter Oturai, Seppo W. Langer, Ulrich Knigge, Flemming L. Andersen and Andreas Kjaer
  
  Journal of Nuclear Medicine June 1, 2023, 64 (6) 951-959; DOI: https://doi.org/10.2967/jnumed.122.264826
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  First Total-Body Kinetic Modeling and Parametric Imaging of Dynamic ⁶⁸Ga-FAPI-04 PET in Pancreatic and Gastric Cancer
  Ruohua Chen, Xinlan Yang, Yee Ling Ng, Xiaofeng Yu, Yanmiao Huo, Xiuying Xiao, Chenpeng Zhang, Yumei Chen, Chaojie Zheng, Lianghua Li, Gang Huang, Yun Zhou and Jianjun Liu
  
  Journal of Nuclear Medicine June 1, 2023, 64 (6) 960-967; DOI: https://doi.org/10.2967/jnumed.122.264988
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  Measurement of Cerebral Perfusion Indices from the Early Phase of [¹⁸F]MK6240 Dynamic Tau PET Imaging
  Nicolas J. Guehl, Maeva Dhaynaut, Bernard J. Hanseeuw, Sung-Hyun Moon, Cristina Lois, Emma Thibault, Jessie Fanglu Fu, Julie C. Price, Keith A. Johnson, Georges El Fakhri and Marc D. Normandin
  
  Journal of Nuclear Medicine June 1, 2023, 64 (6) 968-975; DOI: https://doi.org/10.2967/jnumed.122.265072

Invited Perspective

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Artificial Intelligence Algorithms Need to Be Explainable—or Do They?
Tyler J. Bradshaw, Melissa D. McCradden, Abhinav K. Jha, Joyita Dutta, Babak Saboury, Eliot L. Siegel and Arman Rahmim

Journal of Nuclear Medicine June 1, 2023, 64 (6) 976-977; DOI: https://doi.org/10.2967/jnumed.122.264949

Physics and Instrumentation

Basic
- Open Access
  Submillimeter-Resolution PET for High-Sensitivity Mouse Brain Imaging
  Han Gyu Kang, Hideaki Tashima, Hidekatsu Wakizaka, Fumihiko Nishikido, Makoto Higuchi, Miwako Takahashi and Taiga Yamaya
  
  Journal of Nuclear Medicine June 1, 2023, 64 (6) 978-985; DOI: https://doi.org/10.2967/jnumed.122.264433

Special Contribution

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Theranostic Radiopharmaceuticals: A Universal Challenging Educational Paradigm in Nuclear Medicine
Jean-Luc Urbain, Andrew M. Scott, Sze Ting Lee, John Buscombe, Charlotte Weston, Jun Hatazawa, Seigo Kinuya, Baljinder Singh, Mohamad Haidar, Andrew Ross, Francois Lamoureux, Jolanta Kunikowska, Wolfgang Wadsak, Rudi Dierckx, Diana Paez, Francesco Giammarile, Kyung-Han Lee, Joo Hyun O, Modiselle Moshe, Lizette Louw, Stuart More, Helen Nadel, Daniel Lee and Richard Wahl

Journal of Nuclear Medicine June 1, 2023, 64 (6) 986-991; DOI: https://doi.org/10.2967/jnumed.123.265603

Illustrated Post

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Incidental Focal ⁶⁸Ga-FAPI-46 Uptake in a Urachal Remnant: A Potential Pitfall Mimicking a Malignant Peritoneal Lesion
Peter George Maliha, Mahbod Jafarvard, Johannes Czernin, Jeremie Calais and Masatoshi Hotta

Journal of Nuclear Medicine June 1, 2023, 64 (6) 992; DOI: https://doi.org/10.2967/jnumed.122.265029
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Incidental Airway Findings on PET/CT with ¹⁸F-PSMA
Jason Orciuolo, Akash Sharma, Ephraim E. Parent, Joseph M. Accurso, Manoj K. Jain and Jason R. Young

Journal of Nuclear Medicine June 1, 2023, 64 (6) 993; DOI: https://doi.org/10.2967/jnumed.122.265270

Letters to the Editor

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Molecular Imaging of Pulmonary Inflammation: Claiming That Vaping Is More Harmful Than Smoking Is Unsupported
Riccardo Polosa, Lucia Spicuzza and Stefano Palmucci

Journal of Nuclear Medicine June 1, 2023, 64 (6) 994-995; DOI: https://doi.org/10.2967/jnumed.123.265533
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Reply: Molecular Imaging of Pulmonary Inflammation: Claiming That Vaping Is More Harmful Than Smoking Is Unsupported
Reagan R. Wetherill and Jacob Dubroff

Journal of Nuclear Medicine June 1, 2023, 64 (6) 995; DOI: https://doi.org/10.2967/jnumed.123.265570
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PSMA PET/CT and Therapy Response Evaluation in Metastatic Prostate Cancer: Is It Time to Surpass the Old Way?
Laura Evangelista

Journal of Nuclear Medicine June 1, 2023, 64 (6) 996; DOI: https://doi.org/10.2967/jnumed.122.265308

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About the Cover

This Month in JNM

Message from the SNMMI President

Discussions with Leaders

State of the Art

Continuing Education

Oncology

Clinical

BRIEF COMMUNICATION

Radionuclide Therapy

Clinical

FEATURED CLINICAL INVESTIGATION ARTICLE

Basic

Theranostics

Clinical

BRIEF COMMUNICATION

Basic

Cardiovascular

Clinical

Pulmonary

Basic

FEATURED ARTICLE OF THE MONTH

Radiobiology/Dosimetry

Clinical

AI/Advanced Image Analysis

Clinical

Invited Perspective

Physics and Instrumentation

Basic

Special Contribution

Illustrated Post

Letters to the Editor

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