Journal of Nuclear Medicine: 64 (7)

July 1, 2023; Volume 64,Issue 7

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine July 1, 2023, 64 (7) 6A;

Editor's Page

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JNM Editors’ Choice Awards for 2022
Johannes Czernin

Journal of Nuclear Medicine July 1, 2023, 64 (7) 997; DOI: https://doi.org/10.2967/jnumed.123.266027

Discussions with Leaders

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Leading the European Society of Cardiology
Franz Weidinger, Frank Bengel and Johannes Czernin

Journal of Nuclear Medicine July 1, 2023, 64 (7) 998-1000; DOI: https://doi.org/10.2967/jnumed.123.266017

State of the Art

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Fibroblast Activation Protein Inhibitor–Based Radionuclide Therapies: Current Status and Future Directions
Manish Ora, Neetu Soni, Aftab Hasan Nazar, Manish Dixit, Rohit Singh, Savita Puri, Michael M. Graham and Sanjay Gambhir

Journal of Nuclear Medicine July 1, 2023, 64 (7) 1001-1008; DOI: https://doi.org/10.2967/jnumed.123.265594

Continuing Education

Open Access
Theranostics in Hematooncology
Andreas K. Buck, Sebastian E. Serfling, Sabrina Kraus, Samuel Samnick, Niklas Dreher, Takahiro Higuchi, Leo Rasche, Hermann Einsele and Rudolf A. Werner

Journal of Nuclear Medicine July 1, 2023, 64 (7) 1009-1016; DOI: https://doi.org/10.2967/jnumed.122.265199

Oncology

Basic
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  Site-Specifically Conjugated Single-Domain Antibody Successfully Identifies Glypican-3–Expressing Liver Cancer by Immuno-PET
  Stanley Fayn, A. Paden King, Nicholas T. Gutsche, Zhijian Duan, Jesse Buffington, Colleen P. Olkowski, Ying Fu, Jessica Hong, Deepak Sail, Kwamena E. Baidoo, Rolf E. Swenson, Ross W. Cheloha, Mitchell Ho, Peter L. Choyke and Freddy E. Escorcia
  
  Journal of Nuclear Medicine July 1, 2023, 64 (7) 1017-1023; DOI: https://doi.org/10.2967/jnumed.122.265171

Theranostics

Clinical
- FEATURED ARTICLE OF THE MONTH
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    PSMA PET Tumor–to–Salivary Gland Ratio to Predict Response to [¹⁷⁷Lu]PSMA Radioligand Therapy: An International Multicenter Retrospective Study
    Masatoshi Hotta, Andrei Gafita, Vishnu Murthy, Matthias R. Benz, Ida Sonni, Irene A. Burger, Matthias Eiber, Louise Emmett, Andrea Farolfi, Wolfgang P. Fendler, Manuel M. Weber, Michael S. Hofman, Thomas A. Hope, Clemens Kratochwil, Johannes Czernin and Jeremie Calais
    
    Journal of Nuclear Medicine July 1, 2023, 64 (7) 1024-1029; DOI: https://doi.org/10.2967/jnumed.122.265242
- Open Access
  Staging Prostate Cancer with ⁶⁸Ga-PSMA-11 PET/CT in the Elderly: Is Preimaging Biopsy Imperative?
  Mikhail Kesler, Dan Cohen, Charles Levine, David Sarid, Daniel Keizman, Ofer Yossepowitch and Einat Even-Sapir
  
  Journal of Nuclear Medicine July 1, 2023, 64 (7) 1030-1035; DOI: https://doi.org/10.2967/jnumed.122.265371
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  Delayed Imaging Improves Lesion Detectability in [^99mTc]Tc-PSMA-I&S SPECT/CT in Recurrent Prostate Cancer
  Christoph Berliner, Lisa Steinhelfer, Maythinee Chantadisai, Markus Kroenke, Daniel Koehler, Randi Pose, Peter Bannas, Sophie Knipper, Matthias Eiber and Tobias Maurer
  
  Journal of Nuclear Medicine July 1, 2023, 64 (7) 1036-1042; DOI: https://doi.org/10.2967/jnumed.122.265252
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  ⁶⁸Ga-FAPI PET/CT Interobserver Agreement on Tumor Assessment: An International Multicenter Prospective Study
  Riccardo Mei, Lukas Kessler, Kim M. Pabst, Manuel Weber, Christian Schmidkonz, Christoph Rischpler, Helle Damgaard Zacho, Thomas Hope, Sarah M. Schwarzenböck, Martin Allen-Auerbach, Louise Emmett, Justin Ferdinandus, Marcus Unterrainer, Benedikt M. Schaarschmidt, Lale Umutlu, Andrea Farolfi, Paolo Castellucci, Cristina Nanni, Silvi Telo, Stefano Fanti, Ken Herrmann and Wolfgang P. Fendler
  
  Journal of Nuclear Medicine July 1, 2023, 64 (7) 1043-1048; DOI: https://doi.org/10.2967/jnumed.122.265245
- Open Access
  Superior Tumor Detection for ⁶⁸Ga-FAPI-46 Versus ¹⁸F-FDG PET/CT and Conventional CT in Patients with Cholangiocarcinoma
  Kim M. Pabst, Marija Trajkovic-Arsic, Phyllis F.Y. Cheung, Simone Ballke, Katja Steiger, Timo Bartel, Benedikt M. Schaarschmidt, Aleksandar Milosevic, Robert Seifert, Michael Nader, Lukas Kessler, Jens T. Siveke, Katharina Lueckerath, Stefan Kasper, Ken Herrmann, Nader Hirmas, Hartmut H. Schmidt, Rainer Hamacher and Wolfgang P. Fendler
  
  Journal of Nuclear Medicine July 1, 2023, 64 (7) 1049-1055; DOI: https://doi.org/10.2967/jnumed.122.265215
Basic
- FEATURED BASIC SCIENCE ARTICLE
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    Addition of Peptide Receptor Radiotherapy to Immune Checkpoint Inhibition Therapy Improves Outcomes in Neuroendocrine Tumors
    Shadi A. Esfahani, Carolina De Aguiar Ferreira, Priska Summer, Umar Mahmood and Pedram Heidari
    
    Journal of Nuclear Medicine July 1, 2023, 64 (7) 1056-1061; DOI: https://doi.org/10.2967/jnumed.123.265391
- Open Access
  Evaluation of Candidate Theranostics for ²²⁷Th/⁸⁹Zr Paired Radioimmunotherapy of Lymphoma
  Diane S. Abou, Mark Longtine, Amanda Fears, Nadia Benabdallah, Ryan Unnerstall, Hannah Johnston, Kyuhwan Shim, Abbie Hasson, Hanwen Zhang, David Ulmert, Floriane Mangin, Serife Ozen, Laurent Raibaut, Stéphane Brandès, Michel Meyer, Jean-Claude Chambron, David S. Tatum, Darren Magda, Richard L. Wahl and Daniel L.J. Thorek
  
  Journal of Nuclear Medicine July 1, 2023, 64 (7) 1062-1068; DOI: https://doi.org/10.2967/jnumed.122.264979
- Open Access
  PSMA-GCK01: A Generator-Based ^99mTc/¹⁸⁸Re Theranostic Ligand for the Prostate-Specific Membrane Antigen
  Jens Cardinale, Frederik L. Giesel, Christina Wensky, Hendrik G. Rathke, Uwe Haberkorn and Clemens Kratochwil
  
  Journal of Nuclear Medicine July 1, 2023, 64 (7) 1069-1075; DOI: https://doi.org/10.2967/jnumed.122.264944
- Open Access
  Evaluation of ¹³⁴Ce/¹³⁴La as a PET Imaging Theranostic Pair for ²²⁵Ac α-Radiotherapeutics
  Kondapa Naidu Bobba, Anil P. Bidkar, Niranjan Meher, Cyril Fong, Anju Wadhwa, Suchi Dhrona, Alex Sorlin, Scott Bidlingmaier, Becka Shuere, Jiang He, David M. Wilson, Bin Liu, Youngho Seo, Henry F. VanBrocklin and Robert R. Flavell
  
  Journal of Nuclear Medicine July 1, 2023, 64 (7) 1076-1082; DOI: https://doi.org/10.2967/jnumed.122.265355

Cardiovascular

Clinical
- BRIEF COMMUNICATION
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    Regression of Myocardial ^99mTc-DPD Uptake After Tafamidis Treatment of Cardiac Transthyretin Amyloidosis
    Maria Papathanasiou, Lukas Kessler, Frank M. Bengel, Aiste-Monika Jakstaite, David Kersting, Zohreh Varasteh, Peter Luedike, Alexander Carpinteiro, Ken Herrmann, Tienush Rassaf and Christoph Rischpler
    
    Journal of Nuclear Medicine July 1, 2023, 64 (7) 1083-1086; DOI: https://doi.org/10.2967/jnumed.122.265352

Neurology

Clinical
- Open Access
  Hybrid ¹⁸F-Fluoroethyltyrosine PET and MRI with Perfusion to Distinguish Disease Progression from Treatment-Related Change in Malignant Brain Tumors: The Quest to Beat the Toughest Cases
  Nathaniel J. Smith, Tristan K. Deaton, Wendy Territo, Brian Graner, Andrew Gauger, Scott E. Snyder, Michael L. Schulte, Mark A. Green, Gary D. Hutchins and Michael C. Veronesi
  
  Journal of Nuclear Medicine July 1, 2023, 64 (7) 1087-1092; DOI: https://doi.org/10.2967/jnumed.122.265149
- INVITED PERSPECTIVE
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    Hybrid ¹⁸F-FET PET and Perfusion MRI to Differentiate Disease Progression from Treatment-Related Changes in Malignant Brain Tumors
    Norbert Galldiks and Karl-Josef Langen
    
    Journal of Nuclear Medicine July 1, 2023, 64 (7) 1093-1094; DOI: https://doi.org/10.2967/jnumed.123.265647

Radiobiology/Dosimetry

Clinical
- Open Access
  Multicenter Evaluation of Frequency and Impact of Activity Infiltration in PET Imaging, Including Microscale Modeling of Skin-Absorbed Dose
  John J. Sunderland, Stephen A. Graves, Dusty M. York, Christine A. Mundt and Twyla B. Bartel
  
  Journal of Nuclear Medicine July 1, 2023, 64 (7) 1095-1101; DOI: https://doi.org/10.2967/jnumed.123.265891
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  Voxel-Based Dosimetry Predicts Hepatotoxicity in Hepatocellular Carcinoma Patients Undergoing Radioembolization with ⁹⁰Y Glass Microspheres
  Masao Watanabe, Hong Grafe, Jens Theysohn, Benedikt Schaarschmidt, Johannes Ludwig, Leonie Jochheim, Matthias Jeschke, Hartmut Schmidt, Wolfgang P. Fendler, Alexandros Moraitis, Ken Herrmann, Kelsey L. Pomykala and Manuel Weber
  
  Journal of Nuclear Medicine July 1, 2023, 64 (7) 1102-1108; DOI: https://doi.org/10.2967/jnumed.122.264996
- Open Access
  An International Study of Factors Affecting Variability of Dosimetry Calculations, Part 2: Overall Variabilities in Absorbed Dose
  Julia Brosch-Lenz, Suqi Ke, Hao Wang, Eric Frey, Yuni K. Dewaraja, John Sunderland and Carlos Uribe
  
  Journal of Nuclear Medicine July 1, 2023, 64 (7) 1109-1116; DOI: https://doi.org/10.2967/jnumed.122.265094
- SPECIAL CONTRIBUTION
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    MIRD Pamphlet No. 28, Part 1: MIRDcalc—A Software Tool for Medical Internal Radiation Dosimetry
    Adam L. Kesner, Lukas M. Carter, Juan C. Ocampo Ramos, Daniel Lafontaine, Edmond A. Olguin, Justin L. Brown, Bonnie President, Derek W. Jokisch, Darrell R. Fisher and Wesley E. Bolch
    
    Journal of Nuclear Medicine July 1, 2023, 64 (7) 1117-1124; DOI: https://doi.org/10.2967/jnumed.122.264225
- Open Access
  The Role of Pretherapy Quantitative Imaging and Dosimetry in Radioiodine Therapy for Advanced Thyroid Cancer
  Jan Taprogge, Carla Abreu, Siraj Yusuf, Gemma Ainsworth, Rachel H. Phillip, Jonathan I. Gear, Rebecca Gregory, Francesca Leek, Iain Murray, Amy B. Coulson, Sarah R. Brown, Yong Du, Kate Newbold, Jonathan Wadsley and Glenn D. Flux
  
  Journal of Nuclear Medicine July 1, 2023, 64 (7) 1125-1130; DOI: https://doi.org/10.2967/jnumed.122.264913
- Open Access
  Optimized SPECT Imaging of ²²⁴Ra α-Particle Therapy by ²¹²Pb Photon Emissions
  Lars Tore Gyland Mikalsen, Monika Kvassheim and Caroline Stokke
  
  Journal of Nuclear Medicine July 1, 2023, 64 (7) 1131-1137; DOI: https://doi.org/10.2967/jnumed.122.264455

Radiochemistry/Radiopharmaceuticals

Clinical
- Open Access
  ¹⁶¹Tb-DOTATOC Production Using a Fully Automated Disposable Cassette System: A First Step Toward the Introduction of ¹⁶¹Tb into the Clinic
  Chiara Favaretto, Pascal V. Grundler, Zeynep Talip, Stefan Landolt, Lebogang Sepini, Ulli Köster, Cristina Müller, Roger Schibli, Susanne Geistlich and Nicholas P. van der Meulen
  
  Journal of Nuclear Medicine July 1, 2023, 64 (7) 1138-1144; DOI: https://doi.org/10.2967/jnumed.122.265268

AI/Advanced Image Analysis

Clinical
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  Fully Automated, Fast Motion Correction of Dynamic Whole-Body and Total-Body PET/CT Imaging Studies
  Lalith Kumar Shiyam Sundar, Martin Lyngby Lassen, Sebastian Gutschmayer, Daria Ferrara, Anna Calabrò, Josef Yu, Kilian Kluge, Yiran Wang, Lorenzo Nardo, Philip Hasbak, Andreas Kjaer, Yasser G. Abdelhafez, Guobao Wang, Simon R. Cherry, Benjamin A. Spencer, Ramsey D. Badawi, Thomas Beyer and Otto Muzik
  
  Journal of Nuclear Medicine July 1, 2023, 64 (7) 1145-1153; DOI: https://doi.org/10.2967/jnumed.122.265362
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  High-Temporal-Resolution Lung Kinetic Modeling Using Total-Body Dynamic PET with Time-Delay and Dispersion Corrections
  Yiran Wang, Benjamin A. Spencer, Jeffrey Schmall, Elizabeth Li, Ramsey D. Badawi, Terry Jones, Simon R. Cherry and Guobao Wang
  
  Journal of Nuclear Medicine July 1, 2023, 64 (7) 1154-1161; DOI: https://doi.org/10.2967/jnumed.122.264810

Illustrated Post

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Incidental Detection of a Tenosynovial Giant Cell Tumor of the Thigh on [⁶⁸Ga]Ga-FAPI PET/CT: Presentation of an Unusual Case
Timur Sellmann, Felicitas Staak, Clemens Maurer, Gernot Rott, Oliver Witzke, Wolfgang Fendler, Hans-Ulrich Schildhaus, Lars Erik Podleska, Ken Herrmann and Christoph Rischpler

Journal of Nuclear Medicine July 1, 2023, 64 (7) 1162-1163; DOI: https://doi.org/10.2967/jnumed.118.207761

Letters to the Editor

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Clinical Potential of HER2 PET as a Predictive Biomarker to Guide the Use of Trastuzumab Deruxtecan in Breast Cancer Patients
Romain-David Seban, Laurence Champion, Audrey Bellesoeur, Anne Vincent-Salomon and Francois-Clement Bidard

Journal of Nuclear Medicine July 1, 2023, 64 (7) 1164-1165; DOI: https://doi.org/10.2967/jnumed.123.265434

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Table of Contents

This Month in JNM

Editor's Page

Discussions with Leaders

State of the Art

Continuing Education

Oncology

Basic

Theranostics

Clinical

FEATURED ARTICLE OF THE MONTH

Basic

FEATURED BASIC SCIENCE ARTICLE

Cardiovascular

Clinical

BRIEF COMMUNICATION

Neurology

Clinical

INVITED PERSPECTIVE

Radiobiology/Dosimetry

Clinical

SPECIAL CONTRIBUTION

Radiochemistry/Radiopharmaceuticals

Clinical

AI/Advanced Image Analysis

Clinical

Illustrated Post

Letters to the Editor

In this issue

Issue highlights

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