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Journal of Nuclear Medicine

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Research ArticleThe State of the Art

The Spatial-Temporal Ordering of Amyloid Pathology and Opportunities for PET Imaging

Enrico Fantoni, Lyduine Collij, Isadora Lopes Alves, Christopher Buckley and Gill Farrar; on behalf of the AMYPAD consortium
Journal of Nuclear Medicine February 2020, 61 (2) 166-171; DOI: https://doi.org/10.2967/jnumed.119.235879
Enrico Fantoni
1Pharmaceutical Diagnostics, GE Healthcare, Chalfont St. Giles, Buckinghamshire, United Kingdom; and
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Lyduine Collij
2Department of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
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Isadora Lopes Alves
2Department of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
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Christopher Buckley
1Pharmaceutical Diagnostics, GE Healthcare, Chalfont St. Giles, Buckinghamshire, United Kingdom; and
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Gill Farrar
1Pharmaceutical Diagnostics, GE Healthcare, Chalfont St. Giles, Buckinghamshire, United Kingdom; and
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    FIGURE 1.

    General mapping of amyloid deposition order. aMCI = amnestic mild cognitive impairment; CSF = cerebrospinal fluid; HC = healthy control; SPM = statistical parametric mapping; VOI = volume of interest.

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Journal of Nuclear Medicine: 61 (2)
Journal of Nuclear Medicine
Vol. 61, Issue 2
February 1, 2020
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The Spatial-Temporal Ordering of Amyloid Pathology and Opportunities for PET Imaging
Enrico Fantoni, Lyduine Collij, Isadora Lopes Alves, Christopher Buckley, Gill Farrar
Journal of Nuclear Medicine Feb 2020, 61 (2) 166-171; DOI: 10.2967/jnumed.119.235879

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The Spatial-Temporal Ordering of Amyloid Pathology and Opportunities for PET Imaging
Enrico Fantoni, Lyduine Collij, Isadora Lopes Alves, Christopher Buckley, Gill Farrar
Journal of Nuclear Medicine Feb 2020, 61 (2) 166-171; DOI: 10.2967/jnumed.119.235879
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  • Article
    • Abstract
    • REVIEW OF METHODS USED ACROSS THE LITERATURE
    • DISCUSSION OF APPLIED METHODOLOGIES
    • SYNTHESIS OF RESULTS AND OPPORTUNITIES FOR REGIONAL AMYLOID PET
    • CONCLUDING REMARKS
    • DISCLOSURE
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Keywords

  • amyloid PET
  • staging
  • Spatial-temporal ordering
  • pathology
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