Skip to main content

Main menu

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
    • Continuing Education
    • JNM Podcasts
  • Subscriptions
    • Subscribers
    • Institutional and Non-member
    • Rates
    • Journal Claims
    • Corporate & Special Sales
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI

User menu

  • Subscribe
  • My alerts
  • Log in
  • Log out
  • My Cart

Search

  • Advanced search
Journal of Nuclear Medicine
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI
  • Subscribe
  • My alerts
  • Log in
  • Log out
  • My Cart
Journal of Nuclear Medicine

Advanced Search

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
    • Continuing Education
    • JNM Podcasts
  • Subscriptions
    • Subscribers
    • Institutional and Non-member
    • Rates
    • Journal Claims
    • Corporate & Special Sales
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • View or Listen to JNM Podcast
  • Visit JNM on Facebook
  • Join JNM on LinkedIn
  • Follow JNM on Twitter
  • Subscribe to our RSS feeds
Research ArticleClinical Investigations

Phase I Study of 68Ga-HER2-Nanobody for PET/CT Assessment of HER2 Expression in Breast Carcinoma

Marleen Keyaerts, Catarina Xavier, Johannes Heemskerk, Nick Devoogdt, Hendrik Everaert, Chloé Ackaert, Marian Vanhoeij, Francois P. Duhoux, Thierry Gevaert, Philippe Simon, Denis Schallier, Christel Fontaine, Ilse Vaneycken, Christian Vanhove, Jacques De Greve, Jan Lamote, Vicky Caveliers and Tony Lahoutte
Journal of Nuclear Medicine January 2016, 57 (1) 27-33; DOI: https://doi.org/10.2967/jnumed.115.162024
Marleen Keyaerts
1Nuclear Medicine Department, UZ Brussel, Brussels, Belgium
2In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Catarina Xavier
2In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Johannes Heemskerk
1Nuclear Medicine Department, UZ Brussel, Brussels, Belgium
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nick Devoogdt
2In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium
3Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hendrik Everaert
1Nuclear Medicine Department, UZ Brussel, Brussels, Belgium
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Chloé Ackaert
3Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Marian Vanhoeij
4Department of Oncological Surgery, UZ Brussel, Brussels, Belgium
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Francois P. Duhoux
5Medical Oncology, Cliniques universitaires Saint-Luc, Brussels, Belgium
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Thierry Gevaert
6Department of Radiation Therapy, UZ Brussel, Brussels, Belgium
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Philippe Simon
7Gynecology Senology, Université Libre de Bruxelles Hôpital Erasme, Brussels, Belgium
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Denis Schallier
8Department of Medical Oncology, UZ Brussel, Brussels, Belgium; and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Christel Fontaine
8Department of Medical Oncology, UZ Brussel, Brussels, Belgium; and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ilse Vaneycken
1Nuclear Medicine Department, UZ Brussel, Brussels, Belgium
2In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Christian Vanhove
9Infinity Laboratory, MEDISIP, IbiTech, Ghent University, and iMinds Medical IT, Ghent, Belgium
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jacques De Greve
8Department of Medical Oncology, UZ Brussel, Brussels, Belgium; and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jan Lamote
4Department of Oncological Surgery, UZ Brussel, Brussels, Belgium
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Vicky Caveliers
1Nuclear Medicine Department, UZ Brussel, Brussels, Belgium
2In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tony Lahoutte
1Nuclear Medicine Department, UZ Brussel, Brussels, Belgium
2In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • PDF
Loading

Data supplements

  • Supplemental Data

    Files in this Data Supplement:

    • Supplemental Data
    • Supplemental Video
PreviousNext
Back to top

In this issue

Journal of Nuclear Medicine: 57 (1)
Journal of Nuclear Medicine
Vol. 57, Issue 1
January 1, 2016
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on Journal of Nuclear Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Phase I Study of 68Ga-HER2-Nanobody for PET/CT Assessment of HER2 Expression in Breast Carcinoma
(Your Name) has sent you a message from Journal of Nuclear Medicine
(Your Name) thought you would like to see the Journal of Nuclear Medicine web site.
Citation Tools
Phase I Study of 68Ga-HER2-Nanobody for PET/CT Assessment of HER2 Expression in Breast Carcinoma
Marleen Keyaerts, Catarina Xavier, Johannes Heemskerk, Nick Devoogdt, Hendrik Everaert, Chloé Ackaert, Marian Vanhoeij, Francois P. Duhoux, Thierry Gevaert, Philippe Simon, Denis Schallier, Christel Fontaine, Ilse Vaneycken, Christian Vanhove, Jacques De Greve, Jan Lamote, Vicky Caveliers, Tony Lahoutte
Journal of Nuclear Medicine Jan 2016, 57 (1) 27-33; DOI: 10.2967/jnumed.115.162024

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Phase I Study of 68Ga-HER2-Nanobody for PET/CT Assessment of HER2 Expression in Breast Carcinoma
Marleen Keyaerts, Catarina Xavier, Johannes Heemskerk, Nick Devoogdt, Hendrik Everaert, Chloé Ackaert, Marian Vanhoeij, Francois P. Duhoux, Thierry Gevaert, Philippe Simon, Denis Schallier, Christel Fontaine, Ilse Vaneycken, Christian Vanhove, Jacques De Greve, Jan Lamote, Vicky Caveliers, Tony Lahoutte
Journal of Nuclear Medicine Jan 2016, 57 (1) 27-33; DOI: 10.2967/jnumed.115.162024
Twitter logo Facebook logo LinkedIn logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • Abstract
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • CONCLUSION
    • DISCLOSURE
    • Acknowledgments
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • PDF

Related Articles

  • This Month in JNM
  • PubMed
  • Google Scholar

Cited By...

  • Generation of a Synthetic Single Domain Antibody Library for Radiopharmaceutical Ligand Discovery
  • Optimizing the Therapeutic Index of sdAb-Based Radiopharmaceuticals Using Pretargeting
  • Engineered Nanobodies Bind Theranostic Main Group Metals
  • Making the effect visible - OX40 targeting nanobodies for in vivo imaging of activated T cells
  • Preclinical development of novel PD-L1 tracers and first-in-human study of [68Ga]Ga-NOTA-RW102 in patients with lung cancers
  • Phase II Trial Assessing the Repeatability and Tumor Uptake of [68Ga]Ga-HER2 Single-Domain Antibody PET/CT in Patients with Breast Carcinoma
  • Two birds with one stone: human SIRP{alpha} nanobodies for functional modulation and in vivo imaging of myeloid cells
  • Clinical Potential of HER2 PET as a Predictive Biomarker to Guide the Use of Trastuzumab Deruxtecan in Breast Cancer Patients
  • Targeted {alpha}-Therapy Using 225Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment
  • Targeted {alpha}-Therapy Using 225Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment
  • Single-Domain Antibody Theranostics on the Horizon
  • Gene prediction in the immunoglobulin loci
  • Low Level Whole-Brain Radiation Enhances Theranostic Potential Of Single Domain Antibody Fragments For HER2-Positive Brain Metastases
  • Sensitizing solid tumors to CAR-mediated cytotoxicity using synthetic antigens
  • Site-Specific and Residualizing Linker for 18F Labeling with Enhanced Renal Clearance: Application to an Anti-HER2 Single-Domain Antibody Fragment
  • Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade
  • Converting an Anti-Mouse CD4 Monoclonal Antibody into an scFv Positron Emission Tomography Imaging Agent for Longitudinal Monitoring of CD4+ T Cells
  • Phase I Trial of 131I-GMIB-Anti-HER2-VHH1, a New Promising Candidate for HER2-Targeted Radionuclide Therapy in Breast Cancer Patients
  • Phase I Study of 99mTc-ADAPT6, a Scaffold Protein-Based Probe for Visualization of HER2 Expression in Breast Cancer
  • Quo Vadis, Molecular Imaging?
  • A potent neutralizing nanobody against SARS-CoV-2 with inhaled delivery potential
  • Nanobody-Facilitated Multiparametric PET/MRI Phenotyping of Atherosclerosis
  • Early Phase I Study of a 99mTc-Labeled Anti-Programmed Death Ligand-1 (PD-L1) Single-Domain Antibody in SPECT/CT Assessment of PD-L1 Expression in Non-Small Cell Lung Cancer
  • QnAs with Hidde L. Ploegh
  • 89Zr-labeled Bispecific T-cell Engager AMG 211 PET Shows AMG 211 Accumulation in CD3-rich Tissues and Clear, Heterogeneous Tumor Uptake
  • Anti-MET VHH Pool Overcomes MET-Targeted Cancer Therapeutic Resistance
  • A Novel Nanobody Targeting Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Receptor-Binding Domain Has Potent Cross-Neutralizing Activity and Protective Efficacy against MERS-CoV
  • PET Imaging of Receptor Tyrosine Kinases in Cancer
  • A Gallium-67/68-Labeled Antibody Fragment for Immuno-SPECT/PET Shows Low Renal Radioactivity Without Loss of Tumor Uptake
  • Same-Day Imaging Using Small Proteins: Clinical Experience and Translational Prospects in Oncology
  • First-in-Human Human Epidermal Growth Factor Receptor 2-Targeted Imaging Using 89Zr-Pertuzumab PET/CT: Dosimetry and Clinical Application in Patients with Breast Cancer
  • Theranostic Radiolabeled Anti-CD20 sdAb for Targeted Radionuclide Therapy of Non-Hodgkin Lymphoma
  • 131I-labeled Anti-HER2 Camelid sdAb as a Theranostic Tool in Cancer Treatment
  • Preclinical and clinical applications of specific molecular imaging for HER2-positive breast cancer
  • Noninvasive Imaging of Human Immune Responses in a Human Xenograft Model of Graft-Versus-Host Disease
  • Total-body imaging: Transforming the role of positron emission tomography
  • Detection of HER2-Positive Metastases in Patients with HER2-Negative Primary Breast Cancer Using 89Zr-Trastuzumab PET/CT
  • Preclinical Evaluation of 18F-Labeled Anti-HER2 Nanobody Conjugates for Imaging HER2 Receptor Expression by Immuno-PET
  • Google Scholar

More in this TOC Section

  • Cardiac Presynaptic Sympathetic Nervous Function Evaluated by Cardiac PET in Patients with Chronotropic Incompetence Without Heart Failure
  • Validation and Evaluation of a Vendor-Provided Head Motion Correction Algorithm on the uMI Panorama PET/CT System
  • Prognostic Role of 68Ga-PSMA11 PET–Based Response in Patients with Prostate Cancer Undergoing Taxane-Based Chemotherapy
Show more Clinical Investigations

Similar Articles

Keywords

  • breast carcinoma
  • HER2
  • Nanobody
  • PET/CT
  • phase I
SNMMI

© 2025 SNMMI

Powered by HighWire