Journal of Nuclear Medicine: 55 (4)

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April 1, 2014; Volume 55,Issue 4

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine April 1, 2014, 55 (4) 8A;

SNMMI Newsline

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CMS Issues New Instructions on PET Coverage
Journal of Nuclear Medicine April 1, 2014, 55 (4) 9N-10N;
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House of Delegates Votes for Task Force on SNMMI Governance
Journal of Nuclear Medicine April 1, 2014, 55 (4) 10N;
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NIH Coalition to Speed Disease Target Validation
Journal of Nuclear Medicine April 1, 2014, 55 (4) 11N;
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Brookhaven Names Fowler as Scientist Emeritus
Journal of Nuclear Medicine April 1, 2014, 55 (4) 13N;
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SNMMI Leadership Update: Importance of Developing the Field’s Future Leaders
Journal of Nuclear Medicine April 1, 2014, 55 (4) 15N;
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Newsbriefs
Journal of Nuclear Medicine April 1, 2014, 55 (4) 16N-17N;
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From the Literature
Journal of Nuclear Medicine April 1, 2014, 55 (4) 19N-23N;

Editorial

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A Look Back at JNM 2013
Dominique Delbeke

Journal of Nuclear Medicine April 1, 2014, 55 (4) 24A;

Focus on Molecular Imaging

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Molecular Imaging Biomarkers for Oncology Clinical Trials
David A. Mankoff, Daniel A. Pryma and Amy S. Clark

Journal of Nuclear Medicine April 1, 2014, 55 (4) 525-528; DOI: https://doi.org/10.2967/jnumed.113.126128

Invited Perspectives

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Perspectives on PET/MR Imaging: Are We Ready for Clinical Use?
Luigi Mansi and Andrea Ciarmiello

Journal of Nuclear Medicine April 1, 2014, 55 (4) 529-530; DOI: https://doi.org/10.2967/jnumed.113.133405
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PET/CT with Sodium ¹⁸F-Fluoride for Management of Patients with Prostate Cancer
George M. Segall

Journal of Nuclear Medicine April 1, 2014, 55 (4) 531-533; DOI: https://doi.org/10.2967/jnumed.113.133546

Clinical Investigations

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Targeted Chemoradiation in Metastatic Colorectal Cancer: A Phase I Trial of ¹³¹I-huA33 with Concurrent Capecitabine
Rebecca A. Herbertson, Niall C. Tebbutt, Fook-Thean Lee, Sanjeev Gill, Bridget Chappell, Tina Cavicchiolo, Tim Saunder, Graeme J. O’Keefe, Aurora Poon, Sze Ting Lee, Roger Murphy, Wendie Hopkins, Fiona E. Scott and Andrew M. Scott

Journal of Nuclear Medicine April 1, 2014, 55 (4) 534-539; DOI: https://doi.org/10.2967/jnumed.113.132761
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Comparison of ¹⁸F-FET PET and Perfusion-Weighted MR Imaging: A PET/MR Imaging Hybrid Study in Patients with Brain Tumors
Christian P. Filss, Norbert Galldiks, Gabriele Stoffels, Michael Sabel, Hans J. Wittsack, Bernd Turowski, Gerald Antoch, Ke Zhang, Gereon R. Fink, Heinz H. Coenen, Nadim J. Shah, Hans Herzog and Karl-Josef Langen

Journal of Nuclear Medicine April 1, 2014, 55 (4) 540-545; DOI: https://doi.org/10.2967/jnumed.113.129007
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Focal Changes in Diffusivity on Apparent Diffusion Coefficient MR Imaging and Amino Acid Uptake on PET Do Not Colocalize in Nonenhancing Low-Grade Gliomas
Verena Rahm, Larissa Boxheimer, Matthias Bruehlmeier, Jatta Berberat, Egbert U. Nitzsche, Luca Remonda and Ulrich Roelcke

Journal of Nuclear Medicine April 1, 2014, 55 (4) 546-550; DOI: https://doi.org/10.2967/jnumed.113.130732
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Contrast-Enhanced PET/MR Imaging Versus Contrast-Enhanced PET/CT in Head and Neck Cancer: How Much MR Information Is Needed?
Felix P. Kuhn, Martin Hüllner, Caecilia E. Mader, Nikos Kastrinidis, Gerhard F. Huber, Gustav K. von Schulthess, Spyros Kollias and Patrick Veit-Haibach

Journal of Nuclear Medicine April 1, 2014, 55 (4) 551-558; DOI: https://doi.org/10.2967/jnumed.113.125443
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Quantitative Volumetric CT-Histogram Analysis in N-Staging of ¹⁸F-FDG–Equivocal Patients with Lung Cancer
Paul Flechsig, Clemens Kratochwil, Lawrence H. Schwartz, Daniel Rath, Jan Moltz, Gerald Antoch, Claus-Peter Heussel, Michael Rieser, Arne Warth, Heike Zabeck, Hans-Ulrich Kauczor, Uwe Haberkorn and Frederik L. Giesel

Journal of Nuclear Medicine April 1, 2014, 55 (4) 559-564; DOI: https://doi.org/10.2967/jnumed.113.128504
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¹⁸F-FDG PET Scanning in Pulmonary Amyloidosis
Misbah Baqir, Val Lowe, Eunhee S. Yi and Jay H. Ryu

Journal of Nuclear Medicine April 1, 2014, 55 (4) 565-568; DOI: https://doi.org/10.2967/jnumed.113.130823
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Interim ¹⁸F-FDG PET SUVmax Reduction Is Superior to Visual Analysis in Predicting Outcome Early in Hodgkin Lymphoma Patients
Cédric Rossi, Salim Kanoun, Alina Berriolo-Riedinger, Inna Dygai-Cochet, Olivier Humbert, Caroline Legouge, Marie Lorraine Chrétien, Jean-Noel Bastie, François Brunotte and René-Olivier Casasnovas

Journal of Nuclear Medicine April 1, 2014, 55 (4) 569-573; DOI: https://doi.org/10.2967/jnumed.113.130609
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Impact of ¹⁸F-Fluoride PET in Patients with Known Prostate Cancer: Initial Results from the National Oncologic PET Registry
Bruce E. Hillner, Barry A. Siegel, Lucy Hanna, Fenghai Duan, Anthony F. Shields and R. Edward Coleman

Journal of Nuclear Medicine April 1, 2014, 55 (4) 574-581; DOI: https://doi.org/10.2967/jnumed.113.130005
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Prognostic Value of Metabolic Parameters in Patients with Synchronous Colorectal Cancer Liver Metastasis Following Curative-Intent Colorectal and Hepatic Surgery
Hyo Sang Lee, Hye Ok Kim, Yong Sang Hong, Tae Won Kim, Jin Cheon Kim, Chang Sik Yu and Jae Seung Kim

Journal of Nuclear Medicine April 1, 2014, 55 (4) 582-589; DOI: https://doi.org/10.2967/jnumed.113.128629
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The Lumped Constant for the Galactose Analog 2-¹⁸F-Fluoro-2-Deoxy-d-Galactose Is Increased in Patients with Parenchymal Liver Disease
Kasper S. Mikkelsen, Michael Sørensen, Kim Frisch, Gerda E. Villadsen, Bo M. Bibby and Susanne Keiding

Journal of Nuclear Medicine April 1, 2014, 55 (4) 590-594; DOI: https://doi.org/10.2967/jnumed.113.125559
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Phosphodiesterase 10A PET Radioligand Development Program: From Pig to Human
Christophe Plisson, David Weinzimmer, Steen Jakobsen, Sridhar Natesan, Cristian Salinas, Shu-Fei Lin, David Labaree, Ming-Qiang Zheng, Nabeel Nabulsi, Tiago Reis Marques, Shitij Kapur, Eiji Kawanishi, Takeaki Saijo, Roger N. Gunn, Richard E. Carson and Eugenii A. Rabiner

Journal of Nuclear Medicine April 1, 2014, 55 (4) 595-601; DOI: https://doi.org/10.2967/jnumed.113.131409
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Determination of Accuracy and Precision of Lesion Uptake Measurements in Human Subjects with Time-of-Flight PET
Margaret E. Daube-Witherspoon, Suleman Surti, Amy E. Perkins and Joel S. Karp

Journal of Nuclear Medicine April 1, 2014, 55 (4) 602-607; DOI: https://doi.org/10.2967/jnumed.113.127035

Continuing Education

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Radionuclides in Nephrourology, Part 1: Radiopharmaceuticals, Quality Control, and Quantitative Indices
Andrew T. Taylor

Journal of Nuclear Medicine April 1, 2014, 55 (4) 608-615; DOI: https://doi.org/10.2967/jnumed.113.133447

Basic Science Investigations

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Pharmacokinetic Analysis and Uptake of ¹⁸F-FBPA-Fr After Ultrasound-Induced Blood–Brain Barrier Disruption for Potential Enhancement of Boron Delivery for Neutron Capture Therapy
Feng-Yi Yang, Wen-Yuan Chang, Jia-Je Li, Hsin-Ell Wang, Jyh-Cheng Chen and Chi-Wei Chang

Journal of Nuclear Medicine April 1, 2014, 55 (4) 616-621; DOI: https://doi.org/10.2967/jnumed.113.125716
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Reduced ⁶⁴Cu Uptake and Tumor Growth Inhibition by Knockdown of Human Copper Transporter 1 in Xenograft Mouse Model of Prostate Cancer
Huawei Cai, Jiu-sheng Wu, Otto Muzik, Jer-Tsong Hsieh, Robert J. Lee and Fangyu Peng

Journal of Nuclear Medicine April 1, 2014, 55 (4) 622-628; DOI: https://doi.org/10.2967/jnumed.113.126979
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PET/CT Imaging of Chemokine Receptor CCR5 in Vascular Injury Model Using Targeted Nanoparticle
Hannah P. Luehmann, Eric D. Pressly, Lisa Detering, Cynthia Wang, Richard Pierce, Pamela K. Woodard, Robert J. Gropler, Craig J. Hawker and Yongjian Liu

Journal of Nuclear Medicine April 1, 2014, 55 (4) 629-634; DOI: https://doi.org/10.2967/jnumed.113.132001
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PET Brain Imaging of Neuropeptide Y2 Receptors Using N-¹¹C-Methyl-JNJ-31020028 in Pigs
Michael Winterdahl, Hélène Audrain, Anne M. Landau, Donald F. Smith, Pascal Bonaventure, James R. Shoblock, Nicholas Carruthers, Devin Swanson and Dirk Bender

Journal of Nuclear Medicine April 1, 2014, 55 (4) 635-639; DOI: https://doi.org/10.2967/jnumed.113.125351
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Radiosynthesis and In Vivo Evaluation of Novel Radioligands for PET Imaging of Cerebral 5-HT₇ Receptors
Hanne D. Hansen, Matthias M. Herth, Anders Ettrup, Valdemar L. Andersen, Szabolcs Lehel, Agnete Dyssegaard, Jesper L. Kristensen and Gitte M. Knudsen

Journal of Nuclear Medicine April 1, 2014, 55 (4) 640-646; DOI: https://doi.org/10.2967/jnumed.113.128983
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Acute Administration of Haloperidol Does Not Influence ¹²³I-FP-CIT Binding to the Dopamine Transporter
Jan Booij, Guus van Loon, Kora de Bruin and Pieter Voorn

Journal of Nuclear Medicine April 1, 2014, 55 (4) 647-649; DOI: https://doi.org/10.2967/jnumed.113.132340
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Improved Tumor Targeting of Anti-HER2 Nanobody Through N-Succinimidyl 4-Guanidinomethyl-3-Iodobenzoate Radiolabeling
Marek Pruszynski, Eftychia Koumarianou, Ganesan Vaidyanathan, Hilde Revets, Nick Devoogdt, Tony Lahoutte, H. Kim Lyerly and Michael R. Zalutsky

Journal of Nuclear Medicine April 1, 2014, 55 (4) 650-656; DOI: https://doi.org/10.2967/jnumed.113.127100
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Functional Imaging of Oxidative Stress with a Novel PET Imaging Agent, ¹⁸F-5-Fluoro-l-Aminosuberic Acid
Jack M. Webster, Christine A. Morton, Bruce F. Johnson, Hua Yang, Michael J. Rishel, Brian D. Lee, Qing Miao, Chittari Pabba, Donald T. Yapp and Paul Schaffer

Journal of Nuclear Medicine April 1, 2014, 55 (4) 657-664; DOI: https://doi.org/10.2967/jnumed.113.126664
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In Vivo Visualization of MET Tumor Expression and Anticalin Biodistribution with the MET-Specific Anticalin ⁸⁹Zr-PRS-110 PET Tracer
Anton G.T. Terwisscha van Scheltinga, Marjolijn N. Lub-de Hooge, Marlon J. Hinner, Remy B. Verheijen, Andrea Allersdorfer, Martin Hülsmeyer, Wouter B. Nagengast, Carolien P. Schröder, Jos G.W. Kosterink, Elisabeth G.E. de Vries, Laurent Audoly and Shane A. Olwill

Journal of Nuclear Medicine April 1, 2014, 55 (4) 665-671; DOI: https://doi.org/10.2967/jnumed.113.124941
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¹⁸F-ASEM, a Radiolabeled Antagonist for Imaging the α7-Nicotinic Acetylcholine Receptor with PET
Andrew G. Horti, Yongjun Gao, Hiroto Kuwabara, Yuchuan Wang, Sofya Abazyan, Robert P. Yasuda, Thao Tran, Yingxian Xiao, Niaz Sahibzada, Daniel P. Holt, Kenneth J. Kellar, Mikhail V. Pletnikov, Martin G. Pomper, Dean F. Wong and Robert F. Dannals

Journal of Nuclear Medicine April 1, 2014, 55 (4) 672-677; DOI: https://doi.org/10.2967/jnumed.113.132068
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P21-Driven Multifusion Gene System for Evaluating the Efficacy of Histone Deacetylase Inhibitors by In Vivo Molecular Imaging and for Transcription Targeting Therapy of Cancer Mediated by Histone Deacetylase Inhibitor
Ya-Ju Hsieh, Luen Hwu, Yi-Chieh Chen, Chien-Chih Ke, Fu-Du Chen, Hsin-Ell Wang, Kang-Ping Lin, Hsin-Hsien Yeh, Chi-Wei Chang and Ren-Shyan Liu

Journal of Nuclear Medicine April 1, 2014, 55 (4) 678-685; DOI: https://doi.org/10.2967/jnumed.113.126573
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A Whole-Body Dual-Modality Radionuclide Optical Strategy for Preclinical Imaging of Metastasis and Heterogeneous Treatment Response in Different Microenvironments
Gilbert O. Fruhwirth, Seckou Diocou, Philip J. Blower, Tony Ng and Greg E.D. Mullen

Journal of Nuclear Medicine April 1, 2014, 55 (4) 686-694; DOI: https://doi.org/10.2967/jnumed.113.127480

Book Review

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Lung Cancer Imaging
E. Edmund Kim

Journal of Nuclear Medicine April 1, 2014, 55 (4) 695; DOI: https://doi.org/10.2967/jnumed.114.138321

Letter to the Editor

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Ultra Staging to Unmask the Prescribing of Adjuvant Therapy in Cancer Patients: The Future Opportunity to Image Micrometastases Using Total-Body ¹⁸F-FDG PET Scanning
Patricia M. Price, Ramsey D. Badawi, Simon R. Cherry and Terry Jones

Journal of Nuclear Medicine April 1, 2014, 55 (4) 696-697; DOI: https://doi.org/10.2967/jnumed.113.133892

Erratum

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Erratum
Journal of Nuclear Medicine April 1, 2014, 55 (4) 698;

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