Article Figures & Data
Figures
- FIGURE 1.
Biodistribution of 18F-FLT in C3H/He mice transplanted with SCCVII and in BALB/c nu/nu mice transplanted with HeLa at 1 h after injection. Data are expressed as mean ± SD.
- FIGURE 2.
Changes in relative tumor volume in control mice and x-ray–irradiated mice. Mice bearing SCCVII received 20 Gy at day 0. Data are expressed as mean ± SD. Radiotherapy resulted in tumor shrinkage and no tumor regrowth was found until 14 d after radiation. Tumors grew again after 14 d.
- FIGURE 3.
Tumor uptake of 4 tracers after radiotherapy. Data are expressed as mean ± SD. Asterisks indicate statistically significant differences compared with untreated controls (P < 0.05). Tumor uptake of 18F-FLT decreased significantly at 6 h, 12 h, 24 h, and 3 d after radiotherapy compared with untreated controls. There was a significant decrease in 3H-Thd uptake at 6 h, 12 h, 24 h, 3 d, and 7 d compared with untreated controls. Tumor uptake of 18F-FDG and 14C-DG did not show a statistically significant decrease at 6, 12, and 24 h after radiotherapy.
- FIGURE 4.
Tumor uptake of 4 tracers at 24 h after PDT. Data are expressed as mean ± SD. Asterisks indicate statistically significant differences compared with untreated controls (P < 0.05). A significant decrease of tumor uptake of 18F-FLT and 3H-Thd was observed in PDT-treated tumors. There was no significant difference between untreated controls and PDT-treated tumors in the uptake of 18F-FDG and 14C-DG.
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