Long-Term Nephrotoxicity of 177Lu-PSMA Radioligand Therapy

Lisa Steinhelfer; Lukas Lunger; Lisena Cala; Christian H. Pfob; Constantin Lapa; Philipp E. Hartrampf; Andreas K. Buck; Hannah Schäfer; Christoph Schmaderer; Robert Tauber; Julia Brosch-Lenz; Bernhard Haller; Valentin H. Meissner; Karina Knorr; Wolfgang A. Weber; Matthias Eiber

doi:10.2967/jnumed.123.265986

Research ArticleClinical Investigation

Long-Term Nephrotoxicity of ¹⁷⁷Lu-PSMA Radioligand Therapy

Lisa Steinhelfer, Lukas Lunger, Lisena Cala, Christian H. Pfob, Constantin Lapa, Philipp E. Hartrampf, Andreas K. Buck, Hannah Schäfer, Christoph Schmaderer, Robert Tauber, Julia Brosch-Lenz, Bernhard Haller, Valentin H. Meissner, Karina Knorr, Wolfgang A. Weber and Matthias Eiber

Journal of Nuclear Medicine October 2023, jnumed.123.265986; DOI: https://doi.org/10.2967/jnumed.123.265986

Lisa Steinhelfer

1Department of Nuclear Medicine, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;

2Department of Radiology, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;

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Lukas Lunger

3Department of Urology, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;

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Lisena Cala

1Department of Nuclear Medicine, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;

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Christian H. Pfob

4Nuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany;

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Constantin Lapa

4Nuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany;

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Philipp E. Hartrampf

5Department of Nuclear Medicine, University Hospital Wurzburg, Wurzburg, Germany;

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Andreas K. Buck

5Department of Nuclear Medicine, University Hospital Wurzburg, Wurzburg, Germany;

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Hannah Schäfer

6Department of Nephrology, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; and

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Christoph Schmaderer

6Department of Nephrology, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; and

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Robert Tauber

3Department of Urology, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;

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Julia Brosch-Lenz

1Department of Nuclear Medicine, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;

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Bernhard Haller

7Institute of AI and Informatics in Medicine, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany

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Valentin H. Meissner

3Department of Urology, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;

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Karina Knorr

1Department of Nuclear Medicine, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;

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Wolfgang A. Weber

1Department of Nuclear Medicine, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;

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Matthias Eiber

1Department of Nuclear Medicine, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;

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Vol. 66, Issue 5

May 1, 2025

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Long-Term Nephrotoxicity of ¹⁷⁷Lu-PSMA Radioligand Therapy

Journal of Nuclear Medicine Oct 2023, jnumed.123.265986; DOI: 10.2967/jnumed.123.265986

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Long-Term Nephrotoxicity of ¹⁷⁷Lu-PSMA Radioligand Therapy

Journal of Nuclear Medicine Oct 2023, jnumed.123.265986; DOI: 10.2967/jnumed.123.265986

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Keywords

nephrotoxicity
PSMA
radioligand therapy
lutetium
mCRPC

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