Mathematic Modeling of Tumor Growth During [177Lu]Lu-PSMA Therapy: Insights into Treatment Optimization

Nouran R.R. Zaid; Remco Bastiaannet; Rob Hobbs; George Sgouros

doi:10.2967/jnumed.124.268457

Research ArticleBasic Science Investigation

Mathematic Modeling of Tumor Growth During [¹⁷⁷Lu]Lu-PSMA Therapy: Insights into Treatment Optimization

Nouran R.R. Zaid, Remco Bastiaannet, Rob Hobbs and George Sgouros

Journal of Nuclear Medicine January 2025, 66 (1) 84-90; DOI: https://doi.org/10.2967/jnumed.124.268457

Nouran R.R. Zaid

1Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland; and

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Remco Bastiaannet

1Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland; and

2Department of Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri

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Rob Hobbs

1Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland; and

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George Sgouros

1Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland; and

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Journal of Nuclear Medicine

Vol. 66, Issue 1

January 1, 2025

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Mathematic Modeling of Tumor Growth During [¹⁷⁷Lu]Lu-PSMA Therapy: Insights into Treatment Optimization

Nouran R.R. Zaid, Remco Bastiaannet, Rob Hobbs, George Sgouros

Journal of Nuclear Medicine Jan 2025, 66 (1) 84-90; DOI: 10.2967/jnumed.124.268457

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Mathematic Modeling of Tumor Growth During [¹⁷⁷Lu]Lu-PSMA Therapy: Insights into Treatment Optimization

Nouran R.R. Zaid, Remco Bastiaannet, Rob Hobbs, George Sgouros

Journal of Nuclear Medicine Jan 2025, 66 (1) 84-90; DOI: 10.2967/jnumed.124.268457

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Keywords

radiobiological modeling
Gompertz tumor growth
treatment optimization
[177Lu]Lu-PSMA therapy
pharmacokinetics

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