89Zr-3,2-HOPO-mesothelin antibody PET imaging reflects tumor uptake of mesothelin targeted 227Th-conjugate therapy in mice

Linda N Broer; Daan G Knapen; Frans Valentijn Suurs; Ingrid Moen; Danique Giesen; Stijn J H Waaijer; Baard Indrevoll; Christine Ellingsen; Alexander Kristian; Alan S Cuthbertson; Derk-Jan A de Groot; Patricia E Cole; Elisabeth G.E. de Vries; Urs B Hagemann; Marjolijn N Lub - de Hooge

doi:10.2967/jnumed.121.263079

OtherTheranostics

⁸⁹Zr-3,2-HOPO-mesothelin antibody PET imaging reflects tumor uptake of mesothelin targeted ²²⁷Th-conjugate therapy in mice

Linda N Broer, Daan G Knapen, Frans Valentijn Suurs, Ingrid Moen, Danique Giesen, Stijn J H Waaijer, Baard Indrevoll, Christine Ellingsen, Alexander Kristian, Alan S Cuthbertson, Derk-Jan A de Groot, Patricia E Cole, Elisabeth G.E. de Vries, Urs B Hagemann and Marjolijn N Lub - de Hooge

Journal of Nuclear Medicine April 2022, jnumed.121.263079; DOI: https://doi.org/10.2967/jnumed.121.263079

Linda N Broer

1 University Medical Center Groningen, Netherlands;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Daan G Knapen

1 University Medical Center Groningen, Netherlands;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Frans Valentijn Suurs

1 University Medical Center Groningen, Netherlands;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Ingrid Moen

2 Bayer AS, Norway;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Danique Giesen

1 University Medical Center Groningen, Netherlands;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Stijn J H Waaijer

1 University Medical Center Groningen, Netherlands;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Baard Indrevoll

2 Bayer AS, Norway;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Christine Ellingsen

2 Bayer AS, Norway;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Alexander Kristian

2 Bayer AS, Norway;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Alan S Cuthbertson

2 Bayer AS, Norway;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Derk-Jan A de Groot

1 University Medical Center Groningen, Netherlands;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Patricia E Cole

3 Bayer U.S., United States;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Elisabeth G.E. de Vries

1 University Medical Center Groningen, Netherlands;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Urs B Hagemann

4 Bayer AG, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Marjolijn N Lub - de Hooge

1 University Medical Center Groningen, Netherlands;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Article
Figures & Data
Supplemental
Info & Metrics
PDF

Data supplements

Supplemental Data

Files in this Data Supplement:

Supplemental Data

PreviousNext

In this issue

Journal of Nuclear Medicine

Vol. 66, Issue 5

May 1, 2025

Table of Contents
Table of Contents (PDF)
About the Cover
Index by author
Complete Issue (PDF)

Download PDF

Article Alerts

User Name *

Password *

Email *

Email Article

Thank you for your interest in spreading the word on Journal of Nuclear Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following 89Zr-3,2-HOPO-mesothelin antibody PET imaging reflects tumor uptake of mesothelin targeted 227Th-conjugate therapy in mice

Message Subject (Your Name) has sent you a message from Journal of Nuclear Medicine

Message Body (Your Name) thought you would like to see the Journal of Nuclear Medicine web site.

Your Personal Message

Citation Tools

⁸⁹Zr-3,2-HOPO-mesothelin antibody PET imaging reflects tumor uptake of mesothelin targeted ²²⁷Th-conjugate therapy in mice

Journal of Nuclear Medicine Apr 2022, jnumed.121.263079; DOI: 10.2967/jnumed.121.263079

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

⁸⁹Zr-3,2-HOPO-mesothelin antibody PET imaging reflects tumor uptake of mesothelin targeted ²²⁷Th-conjugate therapy in mice

Journal of Nuclear Medicine Apr 2022, jnumed.121.263079; DOI: 10.2967/jnumed.121.263079

Share This Article:

Tweet Widget
Facebook Like
Google Plus One

Bookmark this article

User Name *

Password *

Remember my user name & password.

Jump to section

Article
Figures & Data
Supplemental
Info & Metrics
PDF

PubMed
Google Scholar

Cited By...

Evaluation of Candidate Theranostics for 227Th/89Zr Paired Radioimmunotherapy of Lymphoma

Google Scholar

Theranostics

Can ¹⁷⁷Lu-DOTATATE Kidney Absorbed Doses be Predicted from Pretherapy SSTR PET? Findings from Multicenter Data
Determination of the Intralesional Distribution of Theranostic ¹²⁴I-Omburtamab Convection-Enhanced Delivery in Treatment of Diffuse Intrinsic Pontine Glioma
Evidence-Based Clinical Protocols to Monitor Efficacy of [¹⁷⁷Lu]Lu-PSMA Radiopharmaceutical Therapy in Metastatic Castration-Resistant Prostate Cancer Using Real-World Data

Show more Theranostics

Basic (Molecular Imaging: Monoclonal Antibodies)

Mesothelin/CD3 Half-Life–Extended Bispecific T-Cell Engager Molecule Shows Specific Tumor Uptake and Distributes to Mesothelin and CD3-Expressing Tissues

Show more Basic (Molecular Imaging: Monoclonal Antibodies)

Keywords

Animal Imaging
Oncology: Pancreas
PET
radionuclide therapy
antibody conjugate
mesothelin
PET imaging
Targeted Thorium-227 Therapy
Zirconium-89

Main menu

User menu

Search

⁸⁹Zr-3,2-HOPO-mesothelin antibody PET imaging reflects tumor uptake of mesothelin targeted ²²⁷Th-conjugate therapy in mice

Data supplements

Supplemental Data

In this issue

Citation Manager Formats

Related Articles

Cited By...

More in this TOC Section

Theranostics

Basic (Molecular Imaging: Monoclonal Antibodies)

Similar Articles

Keywords