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Research ArticleClinical Investigation

Long-Term Nephrotoxicity of 177Lu-PSMA Radioligand Therapy

Lisa Steinhelfer, Lukas Lunger, Lisena Cala, Christian H. Pfob, Constantin Lapa, Philipp E. Hartrampf, Andreas K. Buck, Hannah Schäfer, Christoph Schmaderer, Robert Tauber, Julia Brosch-Lenz, Bernhard Haller, Valentin H. Meissner, Karina Knorr, Wolfgang A. Weber and Matthias Eiber
Journal of Nuclear Medicine January 2024, 65 (1) 79-84; DOI: https://doi.org/10.2967/jnumed.123.265986
Lisa Steinhelfer
1Department of Nuclear Medicine, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;
2Department of Radiology, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;
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Lukas Lunger
3Department of Urology, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;
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Lisena Cala
1Department of Nuclear Medicine, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;
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Christian H. Pfob
4Nuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany;
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Constantin Lapa
4Nuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany;
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Philipp E. Hartrampf
5Department of Nuclear Medicine, University Hospital Wurzburg, Wurzburg, Germany;
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Andreas K. Buck
5Department of Nuclear Medicine, University Hospital Wurzburg, Wurzburg, Germany;
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Hannah Schäfer
6Department of Nephrology, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; and
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Christoph Schmaderer
6Department of Nephrology, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; and
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Robert Tauber
3Department of Urology, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;
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Julia Brosch-Lenz
1Department of Nuclear Medicine, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;
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Bernhard Haller
7Institute of AI and Informatics in Medicine, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany
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Valentin H. Meissner
3Department of Urology, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;
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Karina Knorr
1Department of Nuclear Medicine, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;
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Wolfgang A. Weber
1Department of Nuclear Medicine, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;
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Matthias Eiber
1Department of Nuclear Medicine, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;
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Article Information

vol. 65 no. 1 79-84
DOI 
https://doi.org/10.2967/jnumed.123.265986
PubMed 
37857504

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication May 4, 2023
  • Revision received September 16, 2023
  • Published online January 2, 2024.

Article Versions

  • previous version (October 19, 2023 - 09:02).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2024 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Lisa Steinhelfer*,1,2,
  2. Lukas Lunger*,3,
  3. Lisena Cala1,
  4. Christian H. Pfob4,
  5. Constantin Lapa4,
  6. Philipp E. Hartrampf5,
  7. Andreas K. Buck5,
  8. Hannah Schäfer6,
  9. Christoph Schmaderer6,
  10. Robert Tauber3,
  11. Julia Brosch-Lenz1,
  12. Bernhard Haller7,
  13. Valentin H. Meissner3,
  14. Karina Knorr1,
  15. Wolfgang A. Weber1 and
  16. Matthias Eiber1
  1. 1Department of Nuclear Medicine, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;
  2. 2Department of Radiology, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;
  3. 3Department of Urology, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany;
  4. 4Nuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany;
  5. 5Department of Nuclear Medicine, University Hospital Wurzburg, Wurzburg, Germany;
  6. 6Department of Nephrology, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; and
  7. 7Institute of AI and Informatics in Medicine, School of Medicine, and Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany
  1. For correspondence or reprints, contact Lukas Lunger (lukas.lunger{at}tum.de).
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Long-Term Nephrotoxicity of 177Lu-PSMA Radioligand Therapy
Lisa Steinhelfer, Lukas Lunger, Lisena Cala, Christian H. Pfob, Constantin Lapa, Philipp E. Hartrampf, Andreas K. Buck, Hannah Schäfer, Christoph Schmaderer, Robert Tauber, Julia Brosch-Lenz, Bernhard Haller, Valentin H. Meissner, Karina Knorr, Wolfgang A. Weber, Matthias Eiber
Journal of Nuclear Medicine Jan 2024, 65 (1) 79-84; DOI: 10.2967/jnumed.123.265986

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Long-Term Nephrotoxicity of 177Lu-PSMA Radioligand Therapy
Lisa Steinhelfer, Lukas Lunger, Lisena Cala, Christian H. Pfob, Constantin Lapa, Philipp E. Hartrampf, Andreas K. Buck, Hannah Schäfer, Christoph Schmaderer, Robert Tauber, Julia Brosch-Lenz, Bernhard Haller, Valentin H. Meissner, Karina Knorr, Wolfgang A. Weber, Matthias Eiber
Journal of Nuclear Medicine Jan 2024, 65 (1) 79-84; DOI: 10.2967/jnumed.123.265986
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Keywords

  • nephrotoxicity
  • PSMA
  • radioligand therapy
  • lutetium
  • mCRPC
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