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Research ArticleNeurology

18F-SMBT-1: A Selective and Reversible PET Tracer for Monoamine Oxidase-B Imaging

Ryuichi Harada, Yoshimi Hayakawa, Michinori Ezura, Pradith Lerdsirisuk, Yiqing Du, Yoichi Ishikawa, Ren Iwata, Miho Shidahara, Aiko Ishiki, Akio Kikuchi, Hiroyuki Arai, Yukitsuka Kudo, Kazuhiko Yanai, Shozo Furumoto and Nobuyuki Okamura
Journal of Nuclear Medicine February 2021, 62 (2) 253-258; DOI: https://doi.org/10.2967/jnumed.120.244400
Ryuichi Harada
1Department of Pharmacology, Tohoku University School of Medicine, Sendai, Japan
2Department of Geriatrics and Gerontology, Division of Brain Sciences, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan
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Yoshimi Hayakawa
3Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan
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Michinori Ezura
4Department of Neurology, Tohoku University Graduate School of Medicine. 1-1 Seiryo-machi, Aoba-ku, Sendai, Japan
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Pradith Lerdsirisuk
3Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan
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Yiqing Du
1Department of Pharmacology, Tohoku University School of Medicine, Sendai, Japan
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Yoichi Ishikawa
3Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan
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Ren Iwata
3Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan
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Miho Shidahara
5Department of Quantum Science and Energy Engineering, Tohoku University, Sendai, Japan; and
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Aiko Ishiki
2Department of Geriatrics and Gerontology, Division of Brain Sciences, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan
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Akio Kikuchi
4Department of Neurology, Tohoku University Graduate School of Medicine. 1-1 Seiryo-machi, Aoba-ku, Sendai, Japan
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Hiroyuki Arai
2Department of Geriatrics and Gerontology, Division of Brain Sciences, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan
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Yukitsuka Kudo
2Department of Geriatrics and Gerontology, Division of Brain Sciences, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan
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Kazuhiko Yanai
1Department of Pharmacology, Tohoku University School of Medicine, Sendai, Japan
3Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan
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Shozo Furumoto
3Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan
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Nobuyuki Okamura
3Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan
6Division of Pharmacology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan
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Article Information

vol. 62 no. 2 253-258
DOI 
https://doi.org/10.2967/jnumed.120.244400
PubMed 
32646880

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication March 12, 2020
  • Accepted for publication June 15, 2020
  • Published online January 19, 2021.

Article Versions

  • previous version (July 9, 2020 - 13:00).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2021 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Ryuichi Harada1,2,
  2. Yoshimi Hayakawa3,
  3. Michinori Ezura4,
  4. Pradith Lerdsirisuk3,
  5. Yiqing Du1,
  6. Yoichi Ishikawa3,
  7. Ren Iwata3,
  8. Miho Shidahara5,
  9. Aiko Ishiki2,
  10. Akio Kikuchi4,
  11. Hiroyuki Arai2,
  12. Yukitsuka Kudo2,
  13. Kazuhiko Yanai1,3,
  14. Shozo Furumoto3 and
  15. Nobuyuki Okamura3,6
  1. 1Department of Pharmacology, Tohoku University School of Medicine, Sendai, Japan
  2. 2Department of Geriatrics and Gerontology, Division of Brain Sciences, Institute of Development, Aging, and Cancer, Tohoku University, Sendai, Japan
  3. 3Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan
  4. 4Department of Neurology, Tohoku University Graduate School of Medicine. 1-1 Seiryo-machi, Aoba-ku, Sendai, Japan
  5. 5Department of Quantum Science and Energy Engineering, Tohoku University, Sendai, Japan; and
  6. 6Division of Pharmacology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan
  1. For correspondence or reprints contact: Ryuichi Harada, Department of Pharmacology, Tohoku University School of Medicine, 2-1, Seiryo-machi, Aoba-ku, Sendai 9808575, Japan. E-mail: ryuichi.harada.c8{at}med.tohoku.ac.jp
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Journal of Nuclear Medicine: 62 (2)
Journal of Nuclear Medicine
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February 1, 2021
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18F-SMBT-1: A Selective and Reversible PET Tracer for Monoamine Oxidase-B Imaging
Ryuichi Harada, Yoshimi Hayakawa, Michinori Ezura, Pradith Lerdsirisuk, Yiqing Du, Yoichi Ishikawa, Ren Iwata, Miho Shidahara, Aiko Ishiki, Akio Kikuchi, Hiroyuki Arai, Yukitsuka Kudo, Kazuhiko Yanai, Shozo Furumoto, Nobuyuki Okamura
Journal of Nuclear Medicine Feb 2021, 62 (2) 253-258; DOI: 10.2967/jnumed.120.244400

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18F-SMBT-1: A Selective and Reversible PET Tracer for Monoamine Oxidase-B Imaging
Ryuichi Harada, Yoshimi Hayakawa, Michinori Ezura, Pradith Lerdsirisuk, Yiqing Du, Yoichi Ishikawa, Ren Iwata, Miho Shidahara, Aiko Ishiki, Akio Kikuchi, Hiroyuki Arai, Yukitsuka Kudo, Kazuhiko Yanai, Shozo Furumoto, Nobuyuki Okamura
Journal of Nuclear Medicine Feb 2021, 62 (2) 253-258; DOI: 10.2967/jnumed.120.244400
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