Journal of Nuclear Medicine: 62 (2)

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February 1, 2021; Volume 62,Issue 2

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine February 1, 2021, 62 (2) 10A;

Editor's Page

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The Solutions Come from Science and Knowledge
Johannes Czernin and Caius Radu

Journal of Nuclear Medicine February 1, 2021, 62 (2) 145; DOI: https://doi.org/10.2967/jnumed.120.261792

Discussions with Leaders

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Oliver Sartor Talks with Thomas A. Hope, Jeremie Calais, and Wolfgang P. Fendler About FDA Approval of PSMA
Oliver Sartor, Thomas A. Hope, Jeremie Calais and Wolfgang P. Fendler

Journal of Nuclear Medicine February 1, 2021, 62 (2) 146-148; DOI: https://doi.org/10.2967/jnumed.120.261834

The State of the Art

Open Access
⁶⁸Ga-PSMA-11 NDA Approval: A Novel and Successful Academic Partnership
Giuseppe Carlucci, Robin Ippisch, Roger Slavik, Ashley Mishoe, Joseph Blecha and Shaojun Zhu

Journal of Nuclear Medicine February 1, 2021, 62 (2) 149-155; DOI: https://doi.org/10.2967/jnumed.120.260455

Editorial

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Real-World Data as an Evidence Source in Nuclear Medicine
Ariel B. Bourla and Ken Herrmann

Journal of Nuclear Medicine February 1, 2021, 62 (2) 156-157; DOI: https://doi.org/10.2967/jnumed.120.258665

Hot Topics

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¹¹C Dosimetry Scans Should Be Abandoned
Paolo Zanotti-Fregonara, Adriaan A. Lammertsma and Robert B. Innis

Journal of Nuclear Medicine February 1, 2021, 62 (2) 158-159; DOI: https://doi.org/10.2967/jnumed.120.257402

Focus on Molecular Imaging

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The Latest Developments in Imaging of Fibroblast Activation Protein
Annette Altmann, Uwe Haberkorn and Jens Siveke

Journal of Nuclear Medicine February 1, 2021, 62 (2) 160-167; DOI: https://doi.org/10.2967/jnumed.120.244806

Continuing Education

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Quantitative clinical nuclear cardiology, part 2: Evolving/emerging applications
Piotr J. Slomka, Jonathan B. Moody, Robert J. H. Miller, Jennifer M. Renaud, Edward P. Ficaro and Ernest V. Garcia

Journal of Nuclear Medicine February 1, 2021, 62 (2) 168-176; DOI: https://doi.org/10.2967/jnumed.120.242537

Oncology

Clinical
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  Assessment of Bone Lesions with ¹⁸F-FDG PET Compared with ^99mTc Bone Scintigraphy Leads to Clinically Relevant Differences in Metastatic Breast Cancer Management
  Suzanne C. van Es, Ton Velleman, Sjoerd G. Elias, Frederike Bensch, Adrienne H. Brouwers, Andor W.J.M. Glaudemans, Thomas C. Kwee, Marleen Woltman-van Iersel, John H. Maduro, Sjoukje F. Oosting, Elisabeth G.E. de Vries and Carolina P. Schröder
  
  Journal of Nuclear Medicine February 1, 2021, 62 (2) 177-183; DOI: https://doi.org/10.2967/jnumed.120.244640
- FEATURED ARTICLE OF THE MONTH
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    ¹⁸F-Fluoroestradiol PET Imaging in a Phase II Trial of Vorinostat to Restore Endocrine Sensitivity in ER+/HER2− Metastatic Breast Cancer
    Lanell M. Peterson, Brenda F. Kurland, Fengting Yan, Alena Novakova- Jiresova, Vijayakrishna K. Gadi, Jennifer M. Specht, Julie R. Gralow, Erin K. Schubert, Jeanne M. Link, Kenneth A. Krohn, Janet F. Eary, David A. Mankoff and Hannah M. Linden
    
    Journal of Nuclear Medicine February 1, 2021, 62 (2) 184-190; DOI: https://doi.org/10.2967/jnumed.120.244459
- BRIEF COMMUNICATION
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    Volumetric PET Response Assessment Outperforms Conventional Criteria in Patients Receiving High-Dose Pembrolizumab for Malignant Mesothelioma
    Justin Ferdinandus, Francesco Barbato, Michal Chodyla, Wolfgang P. Fendler, Lukas Kessler, Kelsey L. Pomykala, Martin Metzenmacher, Frederik Krefting, Thomas Hager, Lale Umutlu, Ken Herrmann and Daniel C. Christoph
    
    Journal of Nuclear Medicine February 1, 2021, 62 (2) 191-194; DOI: https://doi.org/10.2967/jnumed.120.245803
Basic
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  Predicting Gemcitabine Delivery by ¹⁸F-FAC PET in Murine Models of Pancreatic Cancer
  James Russell, Milan Grkovski, Isabella J. O’Donoghue, Teja M. Kalidindi, Nagavarakishore Pillarsetty, Eva M. Burnazi, Amanda Kulick, Amber Bahr, Qing Chang, H. Carl LeKaye, Elisa de Stanchina, Kenneth H. Yu and John L. Humm
  
  Journal of Nuclear Medicine February 1, 2021, 62 (2) 195-200; DOI: https://doi.org/10.2967/jnumed.120.246926

Theranostics

Clinical
- Open Access
  FAPI-74 PET/CT Using Either ¹⁸F-AlF or Cold-Kit ⁶⁸Ga Labeling: Biodistribution, Radiation Dosimetry, and Tumor Delineation in Lung Cancer Patients
  Frederik L. Giesel, Sebastian Adeberg, Mustafa Syed, Thomas Lindner, Luis David Jiménez-Franco, Eleni Mavriopoulou, Fabian Staudinger, Eric Tonndorf-Martini, Sebastian Regnery, Stefan Rieken, Rami El Shafie, Manuel Röhrich, Paul Flechsig, Andreas Kluge, Annette Altmann, Jürgen Debus, Uwe Haberkorn and Clemens Kratochwil
  
  Journal of Nuclear Medicine February 1, 2021, 62 (2) 201-207; DOI: https://doi.org/10.2967/jnumed.120.245084
- Open Access
  Diagnostic Accuracy of ¹⁸F-PSMA-1007 PET/CT Imaging for Lymph Node Staging of Prostate Carcinoma in Primary and Biochemical Recurrence
  Katharina Sprute, Vasko Kramer, Stefan A. Koerber, Manuel Meneses, Rene Fernandez, Cristian Soza-Ried, Mathias Eiber, Wolfgang A. Weber, Isabel Rauscher, Kambiz Rahbar, Michael Schaefers, Tadashi Watabe, Motohide Uemura, Sadahiro Naka, Norio Nonomura, Jun Hatazawa, Constantin Schwab, Viktoria Schütz, Markus Hohenfellner, Tim Holland-Letz, Juergen Debus, Clemens Kratochwil, Horacio Amaral, Pete L. Choyke, Uwe Haberkorn, Camilo Sandoval and Frederik L. Giesel
  
  Journal of Nuclear Medicine February 1, 2021, 62 (2) 208-213; DOI: https://doi.org/10.2967/jnumed.120.246363
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  ⁶⁸Ga-PSMA PET/CT for Primary Lymph Node and Distant Metastasis NM Staging of High-Risk Prostate Cancer
  Søren Klingenberg, Mads R. Jochumsen, Benedicte P. Ulhøi, Jacob Fredsøe, Karina D. Sørensen, Michael Borre and Kirsten Bouchelouche
  
  Journal of Nuclear Medicine February 1, 2021, 62 (2) 214-220; DOI: https://doi.org/10.2967/jnumed.120.245605
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  Intraarterial Peptide Receptor Radionuclide Therapy Using ⁹⁰Y-DOTATOC for Hepatic Metastases of Neuroendocrine Tumors
  Courtney Lawhn-Heath, Nicholas Fidelman, Bryant Chee, Salma Jivan, Evan Armstrong, Li Zhang, Sheila Lindsay, Emily K. Bergsland and Thomas A. Hope
  
  Journal of Nuclear Medicine February 1, 2021, 62 (2) 221-227; DOI: https://doi.org/10.2967/jnumed.119.241273
Basic
- BRIEF COMMUNICATION
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    Immune-Checkpoint Blockade Enhances ²²⁵Ac-PSMA617 Efficacy in a Mouse Model of Prostate Cancer
    Johannes Czernin, Kyle Current, Christine E. Mona, Lea Nyiranshuti, Firas Hikmat, Caius G. Radu and Katharina Lückerath
    
    Journal of Nuclear Medicine February 1, 2021, 62 (2) 228-231; DOI: https://doi.org/10.2967/jnumed.120.246041
- Open Access
  Preclinical Characterization of the Radioimmunoconjugate ¹¹¹In or ⁹⁰Y-FF-21101 Against a P-Cadherin–Expressing Tumor in a Mouse Xenograft Model and a Nonhuman Primate
  Yuichi Funase, Eri Nakamura, Masamichi Kajita, Yasutaka Saito, Shinobu Oshikiri, Michi Kitano, Masahiko Tokura, Akihiro Hino and Tomoya Uehara
  
  Journal of Nuclear Medicine February 1, 2021, 62 (2) 232-239; DOI: https://doi.org/10.2967/jnumed.120.245837

Neurology

Clinical
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  One-Stop Shop: ¹⁸F-Flortaucipir PET Differentiates Amyloid-Positive and -Negative Forms of Neurodegenerative Diseases
  Jochen Hammes, Gérard N. Bischof, Karl P. Bohn, Özgür Onur, Anja Schneider, Klaus Fliessbach, Merle C Hönig, Frank Jessen, Bernd Neumaier, Alexander Drzezga and Thilo van Eimeren
  
  Journal of Nuclear Medicine February 1, 2021, 62 (2) 240-246; DOI: https://doi.org/10.2967/jnumed.120.244061
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  Determining Amyloid-β Positivity Using ¹⁸F-AZD4694 PET Imaging
  Joseph Therriault, Andrea L. Benedet, Tharick A. Pascoal, Melissa Savard, Nicholas J. Ashton, Mira Chamoun, Cecile Tissot, Firoza Lussier, Min Su Kang, Gleb Bezgin, Tina Wang, Jaime Fernandes-Arias, Gassan Massarweh, Paolo Vitali, Henrik Zetterberg, Kaj Blennow, Paramita Saha-Chaudhuri, Jean-Paul Soucy, Serge Gauthier and Pedro Rosa-Neto
  
  Journal of Nuclear Medicine February 1, 2021, 62 (2) 247-252; DOI: https://doi.org/10.2967/jnumed.120.245209
Basic
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  ¹⁸F-SMBT-1: A Selective and Reversible PET Tracer for Monoamine Oxidase-B Imaging
  Ryuichi Harada, Yoshimi Hayakawa, Michinori Ezura, Pradith Lerdsirisuk, Yiqing Du, Yoichi Ishikawa, Ren Iwata, Miho Shidahara, Aiko Ishiki, Akio Kikuchi, Hiroyuki Arai, Yukitsuka Kudo, Kazuhiko Yanai, Shozo Furumoto and Nobuyuki Okamura
  
  Journal of Nuclear Medicine February 1, 2021, 62 (2) 253-258; DOI: https://doi.org/10.2967/jnumed.120.244400
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  Preclinical Development of ¹⁸F-OF-NB1 for Imaging GluN2B-Containing N-Methyl-d-Aspartate Receptors and Its Utility as a Biomarker for Amyotrophic Lateral Sclerosis
  Hazem Ahmed, Rahel Wallimann, Ahmed Haider, Vahid Hosseini, Stefan Gruber, Marvin Robledo, Thi A.N. Nguyen, Adrienne Müller Herde, Irina Iten, Claudia Keller, Viola Vogel, Roger Schibli, Bernhard Wünsch, Linjing Mu and Simon M. Ametamey
  
  Journal of Nuclear Medicine February 1, 2021, 62 (2) 259-265; DOI: https://doi.org/10.2967/jnumed.120.246785

Infectious Disease and Inflammation

Clinical
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  Fibroblast Activation Protein–Targeted PET/CT with ⁶⁸Ga-FAPI for Imaging IgG4-Related Disease: Comparison to ¹⁸F-FDG PET/CT
  Yaping Luo, Qingqing Pan, Huaxia Yang, Linyi Peng, Wen Zhang and Fang Li
  
  Journal of Nuclear Medicine February 1, 2021, 62 (2) 266-271; DOI: https://doi.org/10.2967/jnumed.120.244723

Radiobiology/Dosimetry

Clinical
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  Dose–Effect Relationships of ¹⁶⁶Ho Radioembolization in Colorectal Cancer
  Caren van Roekel, Remco Bastiaannet, Maarten L.J. Smits, Rutger C. Bruijnen, Arthur J.A.T. Braat, Hugo W.A.M. de Jong, Sjoerd G. Elias and Marnix G.E.H. Lam
  
  Journal of Nuclear Medicine February 1, 2021, 62 (2) 272-279; DOI: https://doi.org/10.2967/jnumed.120.243832

Molecular Imaging

Basic
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  Molecular Imaging of Very Late Antigen-4 in Acute Lung Injury
  Joseph Haddad, Joseph D. Latoche, Shubhanchi Nigam, Michael C. Bellavia, Kathryn E. Day, Qin Zhu, W. Barry Edwards, Carolyn J. Anderson and Sina Tavakoli
  
  Journal of Nuclear Medicine February 1, 2021, 62 (2) 280-286; DOI: https://doi.org/10.2967/jnumed.120.242347

Physics and Instrumentation

Clinical
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  Ultra-Fast List-Mode Reconstruction of Short PET Frames and Example Applications
  Matthew G. Spangler-Bickell, Timothy W. Deller, Valentino Bettinardi and Floris Jansen
  
  Journal of Nuclear Medicine February 1, 2021, 62 (2) 287-292; DOI: https://doi.org/10.2967/jnumed.120.245597

SNMMI Newsline

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SNMMI Newsline
Journal of Nuclear Medicine February 1, 2021, 62 (2) 11N-22N;
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FDA Approves First PSMA-Targeted PET Drug
Journal of Nuclear Medicine February 1, 2021, 62 (2) 11N;
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2020 SNMMI Highlights Lecture: Neuroscience
Julie Price

Journal of Nuclear Medicine February 1, 2021, 62 (2) 12N-19N;
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SNMMI Leadership Update: Advancing Radiopharmaceutical Therapy
Richard L. Wahl

Journal of Nuclear Medicine February 1, 2021, 62 (2) 20N;
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FDA Announces Priority Review of ¹⁸F-DCFPyL NDA
Journal of Nuclear Medicine February 1, 2021, 62 (2) 21N-22N;

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About the Cover

This Month in JNM

Editor's Page

Discussions with Leaders

The State of the Art

Editorial

Hot Topics

Focus on Molecular Imaging

Continuing Education

Oncology

Clinical

FEATURED ARTICLE OF THE MONTH

BRIEF COMMUNICATION

Basic

Theranostics

Clinical

Basic

BRIEF COMMUNICATION

Neurology

Clinical

Basic

Infectious Disease and Inflammation

Clinical

Radiobiology/Dosimetry

Clinical

Molecular Imaging

Basic

Physics and Instrumentation

Clinical

SNMMI Newsline

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