The Impact of Radiobiologically Informed Dose Prescription on the Clinical Benefit of 90Y SIRT in Colorectal Cancer Patients

Elliot M. Abbott; Nadia Falzone; Boon Q. Lee; Christiana Kartsonaki; Helen Winter; Tessa A. Greenhalgh; Daniel R. McGowan; Nigar Syed; Ana M. Denis-Bacelar; Philip Boardman; Ricky A. Sharma; Katherine A. Vallis

doi:10.2967/jnumed.119.233650

Research ArticleDosimetry

The Impact of Radiobiologically Informed Dose Prescription on the Clinical Benefit of ⁹⁰Y SIRT in Colorectal Cancer Patients

Elliot M. Abbott, Nadia Falzone, Boon Q. Lee, Christiana Kartsonaki, Helen Winter, Tessa A. Greenhalgh, Daniel R. McGowan, Nigar Syed, Ana M. Denis-Bacelar, Philip Boardman, Ricky A. Sharma and Katherine A. Vallis

Journal of Nuclear Medicine November 2020, 61 (11) 1658-1664; DOI: https://doi.org/10.2967/jnumed.119.233650

Elliot M. Abbott

1Oxford Institute for Radiation Oncology, Department of Oncology, Oxford University, Oxford, United Kingdom

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Nadia Falzone

1Oxford Institute for Radiation Oncology, Department of Oncology, Oxford University, Oxford, United Kingdom

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Boon Q. Lee

1Oxford Institute for Radiation Oncology, Department of Oncology, Oxford University, Oxford, United Kingdom

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Christiana Kartsonaki

2Nuffield Department of Population Health, Oxford University, Oxford, United Kingdom

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Helen Winter

3Department of Oncology, Oxford University, Oxford, United Kingdom

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Tessa A. Greenhalgh

3Department of Oncology, Oxford University, Oxford, United Kingdom

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Daniel R. McGowan

4Department of Radiology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom

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Nigar Syed

4Department of Radiology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom

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Ana M. Denis-Bacelar

5National Physical Laboratory, Teddington, United Kingdom; and

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Philip Boardman

4Department of Radiology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom

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Ricky A. Sharma

6Radiation Oncology, University College London, London, United Kingdom

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Katherine A. Vallis

1Oxford Institute for Radiation Oncology, Department of Oncology, Oxford University, Oxford, United Kingdom

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Journal of Nuclear Medicine

Vol. 61, Issue 11

November 1, 2020

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The Impact of Radiobiologically Informed Dose Prescription on the Clinical Benefit of ⁹⁰Y SIRT in Colorectal Cancer Patients

Journal of Nuclear Medicine Nov 2020, 61 (11) 1658-1664; DOI: 10.2967/jnumed.119.233650

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The Impact of Radiobiologically Informed Dose Prescription on the Clinical Benefit of ⁹⁰Y SIRT in Colorectal Cancer Patients

Journal of Nuclear Medicine Nov 2020, 61 (11) 1658-1664; DOI: 10.2967/jnumed.119.233650

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Keywords

colorectal cancer
liver metastases
SIRT
90Y
BED

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