Journal of Nuclear Medicine: 61 (11)

November 1, 2020; Volume 61,Issue 11

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine November 1, 2020, 61 (11) 14A;

Discussions with Leaders

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20 Years of PET/CT: A Conversation with David Townsend and Thomas Beyer
David Townsend, Thomas Beyer and Johannes Czernin

Journal of Nuclear Medicine November 1, 2020, 61 (11) 1541-1543; DOI: https://doi.org/10.2967/jnumed.120.257725

The State of the Art

Open Access
Combination Strategies to Improve Targeted Radionuclide Therapy
Tiffany G. Chan, Edward O’Neill, Christine Habjan and Bart Cornelissen

Journal of Nuclear Medicine November 1, 2020, 61 (11) 1544-1552; DOI: https://doi.org/10.2967/jnumed.120.248062

Continuing Education

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Imaging the Cancer Immune Environment and Its Response to Pharmacologic Intervention, Part 2: The Role of Novel PET Agents
Amir Iravani and Rodney J. Hicks

Journal of Nuclear Medicine November 1, 2020, 61 (11) 1553-1559; DOI: https://doi.org/10.2967/jnumed.120.248823

Oncology

Clinical
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  Prognostic Value of ¹⁸F-FDG PET/CT in a Large Cohort of Patients with Advanced Metastatic Neuroendocrine Neoplasms Treated with Peptide Receptor Radionuclide Therapy
  Jingjing Zhang, Qingxing Liu, Aviral Singh, Christiane Schuchardt, Harshad R. Kulkarni and Richard P. Baum
  
  Journal of Nuclear Medicine November 1, 2020, 61 (11) 1560-1569; DOI: https://doi.org/10.2967/jnumed.119.241414
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  ¹⁸F-FDG PET Assessment of Malignant Pleural Mesothelioma: Total Lesion Volume and Total Lesion Glycolysis—The Central Role of Volume
  James C. Reynolds, Roberto Maass-Moreno, Anish Thomas, Alexander Ling, Emerson B. Padiernos, Seth M. Steinberg and Raffit Hassan
  
  Journal of Nuclear Medicine November 1, 2020, 61 (11) 1570-1575; DOI: https://doi.org/10.2967/jnumed.119.238733
- BRIEF COMMUNICATION
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    PET Imaging Quantifying ⁶⁸Ga-PSMA-11 Uptake in Metastatic Colorectal Cancer
    Tahleesa J. Cuda, Andrew D. Riddell, Cheng Liu, Vicki L. Whitehall, Jennifer Borowsky, David K. Wyld, Matthew E. Burge, Elizabeth Ahern, Alison Griffin, Nicholas J.R. Lyons, Stephen E. Rose, David A. Clark, Andrew R.L. Stevenson, John D. Hooper, Simon Puttick and Paul A. Thomas
    
    Journal of Nuclear Medicine November 1, 2020, 61 (11) 1576-1579; DOI: https://doi.org/10.2967/jnumed.119.233312
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  First-in-Humans Trial of Dasatinib-Derivative Tracer for Tumor Kinase-Targeted PET
  Simone Krebs, Darren R. Veach, Lukas M. Carter, Milan Grkovski, Monica Fornier, Michael J. Mauro, Martin H. Voss, Daniel C. Danila, Eva Burnazi, Manda Null, Kevin Staton, Christina Pressl, Bradley J. Beattie, Pat Zanzonico, Wolfgang A. Weber, Serge K. Lyashchenko, Jason S. Lewis, Steven M. Larson and Mark P.S. Dunphy
  
  Journal of Nuclear Medicine November 1, 2020, 61 (11) 1580-1587; DOI: https://doi.org/10.2967/jnumed.119.234864
Basic
- FEATURED BASIC SCIENCE ARTICLE
  - Open Access
    Receptor-Targeted Photodynamic Therapy of Glucagon-Like Peptide 1 Receptor–Positive Lesions
    Marti Boss, Desiree Bos, Cathelijne Frielink, Gerwin Sandker, Patricia Bronkhorst, Sanne A.M. van Lith, Maarten Brom, Mijke Buitinga and Martin Gotthardt
    
    Journal of Nuclear Medicine November 1, 2020, 61 (11) 1588-1593; DOI: https://doi.org/10.2967/jnumed.119.238998
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  The Biodistribution of a CD3 and EpCAM Bispecific T-Cell Engager Is Driven by the CD3 Arm
  Frans V. Suurs, Grit Lorenczewski, Sabine Stienen, Matthias Friedrich, Elisabeth G.E. de Vries, Derk Jan A. de Groot and Marjolijn N. Lub-de Hooge
  
  Journal of Nuclear Medicine November 1, 2020, 61 (11) 1594-1601; DOI: https://doi.org/10.2967/jnumed.120.241877

Theranostics

Clinical
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    Neuroendocrine Differentiation and Response to PSMA-Targeted Radioligand Therapy in Advanced Metastatic Castration-Resistant Prostate Cancer: A Single-Center Retrospective Study
    Thorsten Derlin, Rudolf A. Werner, Marcel Lafos, Christoph Henkenberens, Christoph A.J. von Klot, Jan M. Sommerlath Sohns, Tobias L. Ross and Frank M. Bengel
    
    Journal of Nuclear Medicine November 1, 2020, 61 (11) 1602-1606; DOI: https://doi.org/10.2967/jnumed.120.241588
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  ⁶⁸Ga-PSMA–Guided Bone Biopsies for Molecular Diagnostics in Patients with Metastatic Prostate Cancer
  Anouk C. de Jong, Minke Smits, Job van Riet, Jurgen J. Fütterer, Tessa Brabander, Paul Hamberg, Inge M. van Oort, Ronald de Wit, Martijn P. Lolkema, Niven Mehra, Marcel Segbers and Astrid A.M. van der Veldt
  
  Journal of Nuclear Medicine November 1, 2020, 61 (11) 1607-1614; DOI: https://doi.org/10.2967/jnumed.119.241109
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  ¹⁸F-DCFPyL PET/CT in Patients with Subclinical Recurrence of Prostate Cancer: Effect of Lesion Size, Smoothing Filter, and Partial-Volume Correction on PROMISE Criteria
  Claudia Ortega, Josh Schaefferkoetter, Patrick Veit-Haibach, Reut Anconina, Alejandro Berlin, Nathan Perlis and Ur Metser
  
  Journal of Nuclear Medicine November 1, 2020, 61 (11) 1615-1620; DOI: https://doi.org/10.2967/jnumed.120.241737

Neurology

Clinical
- FEATURED ARTICLE OF THE MONTH
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    Moving Toward Multicenter Therapeutic Trials in Amyotrophic Lateral Sclerosis: Feasibility of Data Pooling Using Different Translocator Protein PET Radioligands
    Donatienne Van Weehaeghe, Suma Babu, Joke De Vocht, Nicole R. Zürcher, Sheena Chew, Chieh-En J. Tseng, Marco L. Loggia, Michel Koole, Ahmadreza Rezaei, Georg Schramm, Philip Van Damme, Jacob M. Hooker, Koen Van Laere and Nazem Atassi
    
    Journal of Nuclear Medicine November 1, 2020, 61 (11) 1621-1627; DOI: https://doi.org/10.2967/jnumed.119.241059
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  Confirmation of ¹²³I-FP-CIT SPECT Quantification Methods in Dementia with Lewy Bodies and Other Neurodegenerative Disorders
  Daniela D. Maltais, Lennon G. Jordan, Hoon-Ki Min, Toji Miyagawa, Scott A. Przybelski, Timothy G. Lesnick, Robert R. Reichard, Dennis W. Dickson, Melissa E. Murray, Kejal Kantarci, Bradley F. Boeve and Val J. Lowe
  
  Journal of Nuclear Medicine November 1, 2020, 61 (11) 1628-1635; DOI: https://doi.org/10.2967/jnumed.119.239418
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  Kinetic Modeling and Test–Retest Reproducibility of ¹¹C-EKAP and ¹¹C-FEKAP, Novel Agonist Radiotracers for PET Imaging of the κ-Opioid Receptor in Humans
  Mika Naganawa, Songye Li, Nabeel Nabulsi, Shu-fei Lin, David Labaree, Jim Ropchan, Hong Gao, Michael Mei, Shannan Henry, David Matuskey, Richard E. Carson and Yiyun Huang
  
  Journal of Nuclear Medicine November 1, 2020, 61 (11) 1636-1642; DOI: https://doi.org/10.2967/jnumed.119.227694

Cardiovascular

Basic
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  Folate Receptor β–Targeted PET Imaging of Macrophages in Autoimmune Myocarditis
  Arghavan Jahandideh, Sauli Uotila, Mia Ståhle, Jenni Virta, Xiang-Guo Li, Ville Kytö, Päivi Marjamäki, Heidi Liljenbäck, Pekka Taimen, Vesa Oikonen, Jukka Lehtonen, Mikko I. Mäyränpää, Qingshou Chen, Philip S. Low, Juhani Knuuti, Anne Roivainen and Antti Saraste
  
  Journal of Nuclear Medicine November 1, 2020, 61 (11) 1643-1649; DOI: https://doi.org/10.2967/jnumed.119.241356

Pulmonary

Basic
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  Assessing the Activity of Multidrug Resistance–Associated Protein 1 at the Lung Epithelial Barrier
  Severin Mairinger, Johannes A. Sake, Irene Hernández Lozano, Thomas Filip, Michael Sauberer, Johann Stanek, Thomas Wanek, Carsten Ehrhardt and Oliver Langer
  
  Journal of Nuclear Medicine November 1, 2020, 61 (11) 1650-1657; DOI: https://doi.org/10.2967/jnumed.120.244038

Dosimetry

Clinical
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  The Impact of Radiobiologically Informed Dose Prescription on the Clinical Benefit of ⁹⁰Y SIRT in Colorectal Cancer Patients
  Elliot M. Abbott, Nadia Falzone, Boon Q. Lee, Christiana Kartsonaki, Helen Winter, Tessa A. Greenhalgh, Daniel R. McGowan, Nigar Syed, Ana M. Denis-Bacelar, Philip Boardman, Ricky A. Sharma and Katherine A. Vallis
  
  Journal of Nuclear Medicine November 1, 2020, 61 (11) 1658-1664; DOI: https://doi.org/10.2967/jnumed.119.233650

Genitourinary

Translational
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  ¹¹C-PABA as a PET Radiotracer for Functional Renal Imaging: Preclinical and First-in-Human Study
  Camilo A. Ruiz-Bedoya, Alvaro A. Ordonez, Rudolf A. Werner, Donika Plyku, Mariah H. Klunk, Jeff Leal, Wojciech G. Lesniak, Daniel P. Holt, Robert F. Dannals, Takahiro Higuchi, Steven P. Rowe and Sanjay K. Jain
  
  Journal of Nuclear Medicine November 1, 2020, 61 (11) 1665-1671; DOI: https://doi.org/10.2967/jnumed.119.239806

Molecular Imaging

Clinical
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  PET Imaging of Phosphodiesterase-4 Identifies Affected Dysplastic Bone in McCune–Albright Syndrome, a Genetic Mosaic Disorder
  Lora D. Weidner, Yuichi Wakabayashi, Louise A. Stolz, Michael T. Collins, Lori Guthrie, Milalynn Victorino, Joyce Chung, William Miller, Sami S. Zoghbi, Victor W. Pike, Masahiro Fujita, Robert B. Innis and Alison M. Boyce
  
  Journal of Nuclear Medicine November 1, 2020, 61 (11) 1672-1677; DOI: https://doi.org/10.2967/jnumed.120.241976

Physics and Instrumentation

Clinical
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  Data-Driven Respiratory Gating Outperforms Device-Based Gating for Clinical ¹⁸F-FDG PET/CT
  Matthew D. Walker, Andrew J. Morgan, Kevin M. Bradley and Daniel R. McGowan
  
  Journal of Nuclear Medicine November 1, 2020, 61 (11) 1678-1683; DOI: https://doi.org/10.2967/jnumed.120.242248
Basic
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  Benefit of Improved Performance with State-of-the Art Digital PET/CT for Lesion Detection in Oncology
  Suleman Surti, Varsha Viswanath, Margaret E. Daube-Witherspoon, Maurizio Conti, Michael E. Casey and Joel S. Karp
  
  Journal of Nuclear Medicine November 1, 2020, 61 (11) 1684-1690; DOI: https://doi.org/10.2967/jnumed.120.242305

Letters to the Editor

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3D-Printable Platform for High-Throughput Small-Animal Imaging
Lukas M. Carter, Kelly E. Henry, Andre Platzman and Jason S. Lewis

Journal of Nuclear Medicine November 1, 2020, 61 (11) 1691-1692; DOI: https://doi.org/10.2967/jnumed.119.240457
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¹¹C-(+)-PHNO Trapping Reversibility for Quantitative PET Imaging of β-Cell Mass in Patients with Type 1 Diabetes
Eric Laffon and Roger Marthan

Journal of Nuclear Medicine November 1, 2020, 61 (11) 1692-1693; DOI: https://doi.org/10.2967/jnumed.119.241075
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Reply: ¹¹C-(+)-PHNO Trapping Reversibility for Quantitative PET Imaging of β-Cell Mass in Patients with Type 1 Diabetes
Jason Bini, Richard E. Carson and Gary W. Cline

Journal of Nuclear Medicine November 1, 2020, 61 (11) 1693; DOI: https://doi.org/10.2967/jnumed.120.250985
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Interim PET Assessment of Advanced Hodgkin Lymphoma: Is It Sufficient?
Charles Mesguich, Krimo Bouabdallah, Laurence Bordenave, Noël Milpied and Elif Hindié

Journal of Nuclear Medicine November 1, 2020, 61 (11) 1694-1695; DOI: https://doi.org/10.2967/jnumed.120.242594
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Reply: Interim PET Assessment of Advanced Hodgkin Lymphoma: Is It Sufficient?
Deborah M. Stephens, Heiko Schoder, Hongli Li and Jonathan Friedberg

Journal of Nuclear Medicine November 1, 2020, 61 (11) 1695; DOI: https://doi.org/10.2967/jnumed.120.242685

SNMMI Newsline

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SNMMI Newsline
Journal of Nuclear Medicine November 1, 2020, 61 (11) 15N-26N;
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2020 SNMMI Highlights Lecture: Cardiovascular Nuclear and Molecular Imaging
Mehran M. Sadeghi

Journal of Nuclear Medicine November 1, 2020, 61 (11) 15N-22N;
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SNMMI Leadership Update: Research—The Key to Nuclear Medicine’s Past and Future
Alan B. Packard

Journal of Nuclear Medicine November 1, 2020, 61 (11) 23N;
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NRC and Regulatory Relief for Training for Imaging/Localization Studies
Journal of Nuclear Medicine November 1, 2020, 61 (11) 24N-26N;

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Table of Contents

This Month in JNM

Discussions with Leaders

The State of the Art

Continuing Education

Oncology

Clinical

BRIEF COMMUNICATION

Basic

FEATURED BASIC SCIENCE ARTICLE

Theranostics

Clinical

BRIEF COMMUNICATION

Neurology

Clinical

FEATURED ARTICLE OF THE MONTH

Cardiovascular

Basic

Pulmonary

Basic

Dosimetry

Clinical

Genitourinary

Translational

Molecular Imaging

Clinical

Physics and Instrumentation

Clinical

Basic

Letters to the Editor

SNMMI Newsline

In this issue

Issue highlights

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