One-Step 18F-Labeling and Preclinical Evaluation of Prostate-Specific Membrane Antigen Trifluoroborate Probes for Cancer Imaging

Hsiou-Ting Kuo; Mathieu L. Lepage; Kuo-Shyan Lin; Jinhe Pan; Zhengxing Zhang; Zhibo Liu; Alla Pryyma; Chengcheng Zhang; Helen Merkens; Aron Roxin; David M. Perrin; François Bénard

doi:10.2967/jnumed.118.216598

Research ArticleRadiochemistry

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One-Step ¹⁸F-Labeling and Preclinical Evaluation of Prostate-Specific Membrane Antigen Trifluoroborate Probes for Cancer Imaging

Hsiou-Ting Kuo, Mathieu L. Lepage, Kuo-Shyan Lin, Jinhe Pan, Zhengxing Zhang, Zhibo Liu, Alla Pryyma, Chengcheng Zhang, Helen Merkens, Aron Roxin, David M. Perrin and François Bénard

Journal of Nuclear Medicine August 2019, 60 (8) 1160-1166; DOI: https://doi.org/10.2967/jnumed.118.216598

Hsiou-Ting Kuo

1BC Cancer, Vancouver, British Columbia, Canada

2Department of Radiology, University of British Columbia, Vancouver, British Columbia, Canada; and

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Mathieu L. Lepage

3Chemistry Department, University of British Columbia, Vancouver, British Columbia, Canada

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Kuo-Shyan Lin

1BC Cancer, Vancouver, British Columbia, Canada

2Department of Radiology, University of British Columbia, Vancouver, British Columbia, Canada; and

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Jinhe Pan

1BC Cancer, Vancouver, British Columbia, Canada

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Zhengxing Zhang

1BC Cancer, Vancouver, British Columbia, Canada

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Zhibo Liu

3Chemistry Department, University of British Columbia, Vancouver, British Columbia, Canada

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Alla Pryyma

3Chemistry Department, University of British Columbia, Vancouver, British Columbia, Canada

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Chengcheng Zhang

1BC Cancer, Vancouver, British Columbia, Canada

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Helen Merkens

1BC Cancer, Vancouver, British Columbia, Canada

2Department of Radiology, University of British Columbia, Vancouver, British Columbia, Canada; and

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Aron Roxin

1BC Cancer, Vancouver, British Columbia, Canada

3Chemistry Department, University of British Columbia, Vancouver, British Columbia, Canada

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David M. Perrin

3Chemistry Department, University of British Columbia, Vancouver, British Columbia, Canada

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François Bénard

1BC Cancer, Vancouver, British Columbia, Canada

2Department of Radiology, University of British Columbia, Vancouver, British Columbia, Canada; and

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Journal of Nuclear Medicine

Vol. 60, Issue 8

August 1, 2019

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One-Step ¹⁸F-Labeling and Preclinical Evaluation of Prostate-Specific Membrane Antigen Trifluoroborate Probes for Cancer Imaging

Hsiou-Ting Kuo, Mathieu L. Lepage, Kuo-Shyan Lin, Jinhe Pan, Zhengxing Zhang, Zhibo Liu, Alla Pryyma, Chengcheng Zhang, Helen Merkens, Aron Roxin, David M. Perrin, François Bénard

Journal of Nuclear Medicine Aug 2019, 60 (8) 1160-1166; DOI: 10.2967/jnumed.118.216598

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One-Step ¹⁸F-Labeling and Preclinical Evaluation of Prostate-Specific Membrane Antigen Trifluoroborate Probes for Cancer Imaging

Hsiou-Ting Kuo, Mathieu L. Lepage, Kuo-Shyan Lin, Jinhe Pan, Zhengxing Zhang, Zhibo Liu, Alla Pryyma, Chengcheng Zhang, Helen Merkens, Aron Roxin, David M. Perrin, François Bénard

Journal of Nuclear Medicine Aug 2019, 60 (8) 1160-1166; DOI: 10.2967/jnumed.118.216598

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Keywords

PSMA
18F-trifluoroborate
18F labeling
Positron Emission Tomography
prostate cancer

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One-Step ¹⁸F-Labeling and Preclinical Evaluation of Prostate-Specific Membrane Antigen Trifluoroborate Probes for Cancer Imaging

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