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Journal of Nuclear Medicine

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Table of Contents

August 1, 2017; Volume 58,Issue 8

This Month in JNM

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    This Month in JNM
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 8A;

Editor’s Page

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    The Impact of the Impact Factor
    Johannes Czernin
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 1185;

Hot Topics

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    Acceleration of PSMA-Targeted Theranostics to the Clinic: Can Common Sense Prevail?
    Johannes Czernin and Matthias Eiber
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 1186-1187; DOI: https://doi.org/10.2967/jnumed.117.193516

The State of the Art

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    The Use of Microdosing in the Development of Small Organic and Protein Therapeutics
    Mats Bergstrom
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 1188-1195; DOI: https://doi.org/10.2967/jnumed.116.188037

Continuing Education

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    177Lu-PSMA Radioligand Therapy for Prostate Cancer
    Wolfgang P. Fendler, Kambiz Rahbar, Ken Herrmann, Clemens Kratochwil and Matthias Eiber
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 1196-1200; DOI: https://doi.org/10.2967/jnumed.117.191023

Focus on Molecular Imaging

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    Noninvasive Interrogation of Cancer Metabolism with Hyperpolarized 13C MRI
    Andrew Cho, Justin Y.C. Lau, Benjamin J. Geraghty, Charles H. Cunningham and Kayvan R. Keshari
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 1201-1206; DOI: https://doi.org/10.2967/jnumed.116.182170

Editorial

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    Why Targeting of PSMA Is a Valuable Addition to the Management of Castration-Resistant Prostate Cancer: The Urologist’s Point of View
    Boris A. Hadaschik and Martin Boegemann
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 1207-1209; DOI: https://doi.org/10.2967/jnumed.117.194753

Oncology

  • Basic

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      Human Epidermal Growth Factor Receptor 3–Specific Tumor Uptake and Biodistribution of 89Zr-MSB0010853 Visualized by Real-Time and Noninvasive PET Imaging
      Frank J. Warnders, Anton G.T. Terwisscha van Scheltinga, Christine Knuehl, Maarten van Roy, Erik F.J. de Vries, Jos G.W. Kosterink, Elisabeth G.E. de Vries and Marjolijn N. Lub-de Hooge
      Journal of Nuclear Medicine August 1, 2017, 58 (8) 1210-1215; DOI: https://doi.org/10.2967/jnumed.116.181586
  • Translational

    • FEATURED TRANSLATIONAL SCIENCE ARTICLE

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        Preclinical Evaluation of 11C-Sarcosine as a Substrate of Proton-Coupled Amino Acid Transporters and First Human Application in Prostate Cancer
        Morand Piert, Xia Shao, David Raffel, Mathew S. Davenport, Jeffrey Montgomery, Lakshmi Priya Kunju, Brian G. Hockley, Javed Siddiqui, Peter J.H. Scott, Arul M. Chinnaiyan and Thekkelnaycke Rajendiran
        Journal of Nuclear Medicine August 1, 2017, 58 (8) 1216-1223; DOI: https://doi.org/10.2967/jnumed.116.173179
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      First Evaluation of PET-Based Human Biodistribution and Dosimetry of 18F-FAZA, a Tracer for Imaging Tumor Hypoxia
      Annarita Savi, Elena Incerti, Federico Fallanca, Valentino Bettinardi, Francesca Rossetti, Cristina Monterisi, Antonia Compierchio, Giampiero Negri, Piero Zannini, Luigi Gianolli and Maria Picchio
      Journal of Nuclear Medicine August 1, 2017, 58 (8) 1224-1229; DOI: https://doi.org/10.2967/jnumed.113.122671
  • Clinical

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      Equivalent Dose Rate 1 Meter from Neuroendocrine Tumor Patients Exiting the Nuclear Medicine Department After Undergoing Imaging
      Jules Zhang-Yin, Anne-Sophie Dirand, Myriam Sasanelli, Gwenaelle Corrégé, Aude Peudon, Thierry Kiffel, Valérie Nataf, Jérôme Clerc, Françoise Montravers and Jean-Noël Talbot
      Journal of Nuclear Medicine August 1, 2017, 58 (8) 1230-1235; DOI: https://doi.org/10.2967/jnumed.116.187138
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      Functional Imaging Signature of Patients Presenting with Polycythemia/Paraganglioma Syndromes
      Ingo Janssen, Clara C. Chen, Zhenping Zhuang, Corina M. Millo, Katherine I. Wolf, Alexander Ling, Frank I. Lin, Karen T. Adams, Peter Herscovitch, Richard A. Feelders, Antonio T. Fojo, David Taieb, Electron Kebebew and Karel Pacak
      Journal of Nuclear Medicine August 1, 2017, 58 (8) 1236-1242; DOI: https://doi.org/10.2967/jnumed.116.187690
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      The Predictive Value of Early In-Treatment 18F-FDG PET/CT Response to Chemotherapy in Combination with Bevacizumab in Advanced Nonsquamous Non–Small Cell Lung Cancer
      Edwin A. Usmanij, Tinatin Natroshvili, Johanna N.H. Timmer-Bonte, Wim J.G. Oyen, Miep A. van der Drift, Johan Bussink and Lioe-Fee de Geus-Oei
      Journal of Nuclear Medicine August 1, 2017, 58 (8) 1243-1248; DOI: https://doi.org/10.2967/jnumed.116.185314
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      Prognostic Value of Bone Marrow Tracer Uptake Pattern in Baseline PET Scans in Hodgkin Lymphoma: Results from an International Collaborative Study
      Colette Zwarthoed, Tarec Cristoffer El-Galaly, Maria Canepari, Matthieu John Ouvrier, Julien Viotti, Marc Ettaiche, Simonetta Viviani, Luigi Rigacci, Livio Trentin, Chiara Rusconi, Stefano Luminari, Maria Cantonetti, Silvia Bolis, Anna Borra, Jacques Darcourt, Flavia Salvi, Edyta Subocz, Joanna Tajer, Waldemar Kulikowski, Bogdan Malkowski, Jan Maciej Zaucha and Andrea Gallamini
      Journal of Nuclear Medicine August 1, 2017, 58 (8) 1249-1254; DOI: https://doi.org/10.2967/jnumed.116.184218
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      Prospective Evaluation of the Clinical Implications of the Tumor Metabolism and Chemotherapy-Related Changes in Advanced Biliary Tract Cancer
      Jaemin Jo, Hyun Woo Kwon, Seongyeol Park, Do-Youn Oh, Gi Jeong Cheon and Yung-Jue Bang
      Journal of Nuclear Medicine August 1, 2017, 58 (8) 1255-1261; DOI: https://doi.org/10.2967/jnumed.116.186239
    • INVITED PERSPECTIVE

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        MRI and PET: Noninvasive Tools to Probe the Biology of Diffuse Intrinsic Pontine Glioma
        Elizabeth R. Gerstner
        Journal of Nuclear Medicine August 1, 2017, 58 (8) 1262-1263; DOI: https://doi.org/10.2967/jnumed.117.192526
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      Correlation of 18F-FDG PET and MRI Apparent Diffusion Coefficient Histogram Metrics with Survival in Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium
      Katherine A. Zukotynski, Sridhar Vajapeyam, Frederic H. Fahey, Mehmet Kocak, Douglas Brown, Kelsey I. Ricci, Arzu Onar-Thomas, Maryam Fouladi and Tina Young Poussaint
      Journal of Nuclear Medicine August 1, 2017, 58 (8) 1264-1269; DOI: https://doi.org/10.2967/jnumed.116.185389

Theranostics

  • Basic

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      68Ga-THP-PSMA: A PET Imaging Agent for Prostate Cancer Offering Rapid, Room-Temperature, 1-Step Kit-Based Radiolabeling
      Jennifer D. Young, Vincenzo Abbate, Cinzia Imberti, Levente K. Meszaros, Michelle T. Ma, Samantha Y.A. Terry, Robert C. Hider, Greg E. Mullen and Philip J. Blower
      Journal of Nuclear Medicine August 1, 2017, 58 (8) 1270-1277; DOI: https://doi.org/10.2967/jnumed.117.191882

Neurology

  • Basic

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      Determination of an Optimal Pharmacokinetic Model of 18F-FET for Quantitative Applications in Rat Brain Tumors
      Marie Anne Richard, Jérémie P. Fouquet, Réjean Lebel and Martin Lepage
      Journal of Nuclear Medicine August 1, 2017, 58 (8) 1278-1284; DOI: https://doi.org/10.2967/jnumed.116.180612
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      Prediction of the Clinical SUV Ratio in Amyloid PET Imaging Using a Biomathematic Modeling Approach Toward the Efficient Development of a Radioligand
      Yuma Arakawa, YingHwey Nai, Miho Shidahara, Shozo Furumoto, Chie Seki, Nobuyuki Okamura, Manabu Tashiro, Yukitsuka Kudo, Kazuhiko Yanai, Kohsuke Gonda and Hiroshi Watabe
      Journal of Nuclear Medicine August 1, 2017, 58 (8) 1285-1292; DOI: https://doi.org/10.2967/jnumed.116.183566
  • Clinical

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      Glucose Metabolic Profile by Visual Assessment Combined with Statistical Parametric Mapping Analysis in Pediatric Patients with Epilepsy
      Yuankai Zhu, Jianhua Feng, Shuang Wu, Haifeng Hou, Jianfeng Ji, Kai Zhang, Qing Chen, Lin Chen, Haiying Cheng, Liuyan Gao, Zexin Chen, Hong Zhang and Mei Tian
      Journal of Nuclear Medicine August 1, 2017, 58 (8) 1293-1299; DOI: https://doi.org/10.2967/jnumed.116.187492
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      Optimal Reference Region to Measure Longitudinal Amyloid-β Change with 18F-Florbetaben PET
      Santiago Bullich, Victor L. Villemagne, Ana M. Catafau, Aleksandar Jovalekic, Norman Koglin, Christopher C. Rowe and Susan De Santi
      Journal of Nuclear Medicine August 1, 2017, 58 (8) 1300-1306; DOI: https://doi.org/10.2967/jnumed.116.187351
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      Diagnostic Value of 18F-FDG PET/CT Versus MRI in the Setting of Antibody-Specific Autoimmune Encephalitis
      Lilja B. Solnes, Krystyna M. Jones, Steven P. Rowe, Puskar Pattanayak, Abhinav Nalluri, Arun Venkatesan, John C. Probasco and Mehrbod S. Javadi
      Journal of Nuclear Medicine August 1, 2017, 58 (8) 1307-1313; DOI: https://doi.org/10.2967/jnumed.116.184333
    • FEATURED CLINICAL INVESTIGATION ARTICLE

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        Resting-State Networks as Simultaneously Measured with Functional MRI and PET
        Alexandre Savio, Sarah Fünger, Masoud Tahmasian, Srinivas Rachakonda, Andrei Manoliu, Christian Sorg, Timo Grimmer, Vince Calhoun, Alexander Drzezga, Valentin Riedl and Igor Yakushev
        Journal of Nuclear Medicine August 1, 2017, 58 (8) 1314-1317; DOI: https://doi.org/10.2967/jnumed.116.185835

Cardiology

  • Basic

    • FEATURED ARTICLE OF THE MONTH

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        Preclinical Evaluation of RYM1, a Matrix Metalloproteinase–Targeted Tracer for Imaging Aneurysm
        Jakub Toczek, Yunpeng Ye, Kiran Gona, Hye-Yeong Kim, Jinah Han, Mahmoud Razavian, Reza Golestani, Jiasheng Zhang, Terence L. Wu, Jae-Joon Jung and Mehran M. Sadeghi
        Journal of Nuclear Medicine August 1, 2017, 58 (8) 1318-1323; DOI: https://doi.org/10.2967/jnumed.116.188656
  • Clinical

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      Inter- and Intraobserver Agreement of 18F-FDG PET/CT Image Interpretation in Patients Referred for Assessment of Cardiac Sarcoidosis
      Hiroshi Ohira, Brian Mc Ardle, Robert A. deKemp, Pablo Nery, Daniel Juneau, Jennifer M. Renaud, Ran Klein, Owen Clarkin, Karen MacDonald, Eugene Leung, Girish Nair, Rob Beanlands and David Birnie
      Journal of Nuclear Medicine August 1, 2017, 58 (8) 1324-1329; DOI: https://doi.org/10.2967/jnumed.116.187203

Radiation Biology

  • BRIEF COMMUNICATION

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      Human Dosimetry of the N-Methyl-d-Aspartate Receptor Ligand 11C-GMOM
      Jasper van der Aart, Thalia F. van der Doef, Paul Horstman, Marc C. Huisman, Robert C. Schuit, Arthur van Lingen, Albert D. Windhorst, Bart N.M. van Berckel and Adriaan A. Lammertsma
      Journal of Nuclear Medicine August 1, 2017, 58 (8) 1330-1333; DOI: https://doi.org/10.2967/jnumed.116.188250
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    Resin Versus Glass Microspheres for 90Y Transarterial Radioembolization: Comparing Survival in Unresectable Hepatocellular Carcinoma Using Pretreatment Partition Model Dosimetry
    Axel Van Der Gucht, Mario Jreige, Alban Denys, Paul Blanc-Durand, Ariane Boubaker, Anastasia Pomoni, Periklis Mitsakis, Marina Silva-Monteiro, Silvano Gnesin, Marie Nicod Lalonde, Rafael Duran, John O. Prior and Niklaus Schaefer
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 1334-1340; DOI: https://doi.org/10.2967/jnumed.116.184713

Special Contribution

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    Joint SNMMI–ASNC Expert Consensus Document on the Role of 18F-FDG PET/CT in Cardiac Sarcoid Detection and Therapy Monitoring
    Panithaya Chareonthaitawee, Rob S. Beanlands, Wengen Chen, Sharmila Dorbala, Edward J. Miller, Venkatesh L. Murthy, David H. Birnie, Edward S. Chen, Leslie T. Cooper, Roderick H. Tung, Eric S. White, Salvador Borges-Neto, Marcelo F. Di Carli, Robert J. Gropler, Terrence D. Ruddy, Thomas H. Schindler and Ron Blankstein
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 1341-1353; DOI: https://doi.org/10.2967/jnumed.117.196287

Letters to the Editor

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    The Need for Prudence When Using 18F-FDG PET as a Reference Standard for Lymphoma Detection
    Hugo J.A. Adams and Thomas C. Kwee
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 1354-1355; DOI: https://doi.org/10.2967/jnumed.116.187096
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    Reply: The Need for Prudence When Using 18F-FDG PET as a Reference Standard for Lymphoma Detection
    Sue C. Kaste, Monika Metzger and Barry L. Shulkin
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 1355; DOI: https://doi.org/10.2967/jnumed.117.190652
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    Linear No-Threshold Hypothesis at the Hospital: When Radioprotection Becomes a Nosocomial Hazard
    Paolo Zanotti-Fregonara and Elif Hindie
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 1355; DOI: https://doi.org/10.2967/jnumed.117.190983
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    Subjecting Radiologic Imaging to the Linear No-Threshold Hypothesis: A Non Sequitur!
    Edward B. Silberstein
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 1356; DOI: https://doi.org/10.2967/jnumed.117.192690

SNMMI Newsline

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    SNMMI Annual Meeting Highlights Theranostics, Novel Research, and Image of the Year
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 9N-10N;
  • You have access
    New Officers for SNMMI and SNMMI-TS
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 11N-13N;
  • You have access
    Lassmann Recognized with Loevinger–Berman Award
    George Sgouros and Frederic Fahey; on behalf of the SNMMI Medical Internal Radiation Dose Committee
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 14N;
  • You have access
    SNMMI New Fellows Honored
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 15N;
  • You have access
    USP to Establish New General Chapter on Compounding
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 15N;
  • You have access
    In Memoriam: Dirk J. Kwekkeboom, MD, PhD 1958–2017
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 16N;
  • You have access
    New Grants for TBI Research Previewed
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 16N;
  • You have access
    Letter to the Editor: AUC for V/Q Imaging in Pulmonary Embolism. The Elephant in the Room: Planar or SPECT V/Q?
    Pierre-Yves Le Roux and Pierre-Yves Salaun
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 17N;
  • You have access
    SNMMI Leadership Update: The SNMMI 2017 Annual Meeting: Ushering in the Future with a Focus on Theranostics, Research, Education, and Value
    Virginia Pappas
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 18N;
  • You have access
    Science Briefs from the SNMMI 2017 Annual Meeting
    Journal of Nuclear Medicine August 1, 2017, 58 (8) 19N-20N;
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In this issue

Journal of Nuclear Medicine: 58 (8)
Journal of Nuclear Medicine
Vol. 58, Issue 8
August 1, 2017
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author

Issue highlights

  • Preclinical Evaluation of RYM1, a Matrix Metalloproteinase–Targeted Tracer for Imaging Aneurysm
  • Resting-State Networks as Simultaneously Measured with Functional MRI and PET
  • Preclinical Evaluation of 11C-Sarcosine as a Substrate of Proton-Coupled Amino Acid Transporters and First Human Application in Prostate Cancer
  • The Use of Microdosing in the Development of Small Organic and Protein Therapeutics
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    • Translational
      • FEATURED TRANSLATIONAL SCIENCE ARTICLE
    • Clinical
      • INVITED PERSPECTIVE
  • Theranostics
    • Basic
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      • FEATURED CLINICAL INVESTIGATION ARTICLE
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  • MIRD Pamphlet No. 28, Part 1: MIRDcalc—A Software Tool for Medical Internal Radiation Dosimetry
  • Absorbed Dose–Response Relationship in Patients with Gastroenteropancreatic Neuroendocrine Tumors Treated with [177Lu]Lu-DOTATATE: One Step Closer to Personalized Medicine
  • Prediction of 177Lu-DOTATATE PRRT Outcome Using Multimodality Imaging in Patients with Gastroenteropancreatic Neuroendocrine Tumors: Results from a Prospective Phase II LUMEN Study
  • Renal and Multiorgan Safety of 177Lu-PSMA-617 in Patients with Metastatic Castration-Resistant Prostate Cancer in the VISION Dosimetry Substudy
  • High-Temporal-Resolution Lung Kinetic Modeling Using Total-Body Dynamic PET with Time-Delay and Dispersion Corrections
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