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Research ArticleClinical Investigations

Partial-Volume Effect Correction Improves Quantitative Analysis of 18F-Florbetaben β-Amyloid PET Scans

Michael Rullmann, Juergen Dukart, Karl-Titus Hoffmann, Julia Luthardt, Solveig Tiepolt, Marianne Patt, Hermann-Josef Gertz, Matthias L. Schroeter, John Seibyl, Walter J. Schulz-Schaeffer, Osama Sabri and Henryk Barthel
Journal of Nuclear Medicine February 2016, 57 (2) 198-203; DOI: https://doi.org/10.2967/jnumed.115.161893
Michael Rullmann
1Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany
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Juergen Dukart
2LREN, Département des Neurosciences Cliniques, CHUV, Université de Lausanne, Lausanne, Switzerland
3Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
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Karl-Titus Hoffmann
4Department of Neuroradiology, University of Leipzig, Leipzig, Germany
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Julia Luthardt
1Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany
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Solveig Tiepolt
1Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany
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Marianne Patt
1Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany
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Hermann-Josef Gertz
5Department of Psychiatry, University of Leipzig, Leipzig, Germany
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Matthias L. Schroeter
3Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
6Clinic for Cognitive Neurology, University Hospital Leipzig, Leipzig, Germany
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John Seibyl
7Molecular NeuroImaging, L.L.C., New Haven, Connecticut; and
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Walter J. Schulz-Schaeffer
8Department of Neuropathology, University Medical Center, Goettingen, Germany
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Osama Sabri
1Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany
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Henryk Barthel
1Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany
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Article Information

vol. 57 no. 2 198-203
DOI 
https://doi.org/10.2967/jnumed.115.161893
PubMed 
26541776

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication June 5, 2015
  • Accepted for publication October 21, 2015
  • Published online February 1, 2016.

Article Versions

  • previous version (November 5, 2015 - 06:07).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2016 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Author Information

  1. Michael Rullmann1,
  2. Juergen Dukart2,3,
  3. Karl-Titus Hoffmann4,
  4. Julia Luthardt1,
  5. Solveig Tiepolt1,
  6. Marianne Patt1,
  7. Hermann-Josef Gertz5,
  8. Matthias L. Schroeter3,6,
  9. John Seibyl7,
  10. Walter J. Schulz-Schaeffer8,
  11. Osama Sabri1 and
  12. Henryk Barthel1
  1. 1Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany
  2. 2LREN, Département des Neurosciences Cliniques, CHUV, Université de Lausanne, Lausanne, Switzerland
  3. 3Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
  4. 4Department of Neuroradiology, University of Leipzig, Leipzig, Germany
  5. 5Department of Psychiatry, University of Leipzig, Leipzig, Germany
  6. 6Clinic for Cognitive Neurology, University Hospital Leipzig, Leipzig, Germany
  7. 7Molecular NeuroImaging, L.L.C., New Haven, Connecticut; and
  8. 8Department of Neuropathology, University Medical Center, Goettingen, Germany
  1. For correspondence or reprints contact: Michael Rullmann, University of Leipzig, Department of Nuclear Medicine, Liebigstrasse 18, D-04103 Leipzig, Germany. rullmann{at}medizin.uni-leipzig.de
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Journal of Nuclear Medicine: 57 (2)
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February 1, 2016
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Partial-Volume Effect Correction Improves Quantitative Analysis of 18F-Florbetaben β-Amyloid PET Scans
Michael Rullmann, Juergen Dukart, Karl-Titus Hoffmann, Julia Luthardt, Solveig Tiepolt, Marianne Patt, Hermann-Josef Gertz, Matthias L. Schroeter, John Seibyl, Walter J. Schulz-Schaeffer, Osama Sabri, Henryk Barthel
Journal of Nuclear Medicine Feb 2016, 57 (2) 198-203; DOI: 10.2967/jnumed.115.161893

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Partial-Volume Effect Correction Improves Quantitative Analysis of 18F-Florbetaben β-Amyloid PET Scans
Michael Rullmann, Juergen Dukart, Karl-Titus Hoffmann, Julia Luthardt, Solveig Tiepolt, Marianne Patt, Hermann-Josef Gertz, Matthias L. Schroeter, John Seibyl, Walter J. Schulz-Schaeffer, Osama Sabri, Henryk Barthel
Journal of Nuclear Medicine Feb 2016, 57 (2) 198-203; DOI: 10.2967/jnumed.115.161893
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Keywords

  • partial-volume effect correction
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  • β-amyloid
  • florbetaben
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