Unexpected Sensitivity of sst2 Antagonists to N-Terminal Radiometal Modifications

Melpomeni Fani; Friederike Braun; Beatrice Waser; Karin Beetschen; Renzo Cescato; Judit Erchegyi; Jean E. Rivier; Wolfgang A. Weber; Helmut R. Maecke; Jean Claude Reubi

doi:10.2967/jnumed.112.102764

Research ArticleBasic Science Investigations

Unexpected Sensitivity of sst₂ Antagonists to N-Terminal Radiometal Modifications

Melpomeni Fani, Friederike Braun, Beatrice Waser, Karin Beetschen, Renzo Cescato, Judit Erchegyi, Jean E. Rivier, Wolfgang A. Weber, Helmut R. Maecke and Jean Claude Reubi

Journal of Nuclear Medicine September 2012, 53 (9) 1481-1489; DOI: https://doi.org/10.2967/jnumed.112.102764

Melpomeni Fani

1Department of Nuclear Medicine, University Hospital Freiburg, Freiburg, Germany

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Friederike Braun

1Department of Nuclear Medicine, University Hospital Freiburg, Freiburg, Germany

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Beatrice Waser

2Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Berne, Berne, Switzerland; and

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Karin Beetschen

2Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Berne, Berne, Switzerland; and

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Renzo Cescato

2Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Berne, Berne, Switzerland; and

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Judit Erchegyi

3Clayton Foundation Laboratories for Peptide Biology, Salk Institute for Biological Studies, La Jolla, California

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Jean E. Rivier

3Clayton Foundation Laboratories for Peptide Biology, Salk Institute for Biological Studies, La Jolla, California

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Wolfgang A. Weber

1Department of Nuclear Medicine, University Hospital Freiburg, Freiburg, Germany

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Helmut R. Maecke

1Department of Nuclear Medicine, University Hospital Freiburg, Freiburg, Germany

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Jean Claude Reubi

2Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Berne, Berne, Switzerland; and

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Unexpected Sensitivity of sst₂ Antagonists to N-Terminal Radiometal Modifications

Melpomeni Fani, Friederike Braun, Beatrice Waser, Karin Beetschen, Renzo Cescato, Judit Erchegyi, Jean E. Rivier, Wolfgang A. Weber, Helmut R. Maecke, Jean Claude Reubi

Journal of Nuclear Medicine Sep 2012, 53 (9) 1481-1489; DOI: 10.2967/jnumed.112.102764

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Unexpected Sensitivity of sst₂ Antagonists to N-Terminal Radiometal Modifications

Melpomeni Fani, Friederike Braun, Beatrice Waser, Karin Beetschen, Renzo Cescato, Judit Erchegyi, Jean E. Rivier, Wolfgang A. Weber, Helmut R. Maecke, Jean Claude Reubi

Journal of Nuclear Medicine Sep 2012, 53 (9) 1481-1489; DOI: 10.2967/jnumed.112.102764

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