Article Figures & Data
Figures
- FIGURE 1.
Ascending aorta, right ventricle, and lung time–activity curves (A), ratio of 15O2 to whole-blood concentrations (B), compartment model fit of 15O-water radioactivity concentration in blood (C), and resulting 15O2 and 15O-water input functions (D) for typical patient during 15O2 inhalation.
- FIGURE 2.
Simulation study: mean bias (± SD) of fitted OEF relative to true (simulated) OEF (A) and correlation coefficient (r2; B) between fitted and true values for all models.
- FIGURE 3.
Clinical study: average test–retest variability of OEF using models 1–5. Av myocardium = average myocardium.
- FIGURE 4.
Clinical study: correlation (A) and Bland–Altman (B) plots of OEF determined using model 3 for LVW.
- FIGURE 5.
Clinical study: whole-myocardium OEF values in patients as determined using models 1–5.
Tables
Model OEF MBF α VA VRV VBL/VL Number* 1 15O2 15O-water 15O-water C15O NA C15O/μ-map 1 2 15O2 15O-water 15O-water 15O-water 15O-water C15O/μ-map 1 3 15O2 15O-water 15O-water 15O-water 15O-water 15O-water/μ-map 1 4 15O2 15O-water 15O-water 15O-water 15O-water C15O/15O2 2 5 15O2 15O-water 15O-water 15O-water 15O-water 15O-water/15O2 2 6 15O2 15O-water 15O-water 15O2 15O2 15O-water/15O2 4 7 15O2 15O-water 15O2 15O2 15O2 15O-water/15O2 5 8 15O2 15O2/15O-water 15O2/15O-water 15O2/15O-water 15O2/15O-water C15O/μ-map/15O2 6† 9 15O2 15O2 15O2 15O2 15O2 C15O/μ-map 5 Model ROI 1 2 3 4 5 Average myocardium 0.96 0.75 0.70 0.68 0.66 LVW plus septum 0.76 0.85 0.84 0.84 0.72 LVW 0.99 0.75 0.80 0.71 0.14 RVW 0.63 0.54 0.57 0.54 0.58 Septum 0.87 0.70 0.72 0.78 0.81
Supplemental Data
Files in this Data Supplement:
Jump to section
Related Articles
Cited By...
- 11C-Acetate Clearance as an Index of Oxygen Consumption of the Right Myocardium in Idiopathic Pulmonary Arterial Hypertension: A Validation Study Using 15O-Labeled Tracers and PET
- Supine-exercise-induced oxygen supply to the right myocardium is attenuated in patients with severe idiopathic pulmonary arterial hypertension
- Right Ventricular Failure in Idiopathic Pulmonary Arterial Hypertension Is Associated With Inefficient Myocardial Oxygen Utilization