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Journal of Nuclear Medicine

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OtherCONTINUING EDUCATION

18F-FDG PET/CT for Image-Guided and Intensity-Modulated Radiotherapy

Eric C. Ford, Joseph Herman, Ellen Yorke and Richard L. Wahl
Journal of Nuclear Medicine October 2009, 50 (10) 1655-1665; DOI: https://doi.org/10.2967/jnumed.108.055780
Eric C. Ford
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Joseph Herman
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Ellen Yorke
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Richard L. Wahl
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Abstract

Advances in technology have allowed extremely precise control of radiation dose delivery and localization within a patient. The ability to confidently delineate target tumor boundaries, however, has lagged behind. 18F-FDG PET/CT, with its ability to distinguish metabolically active disease from normal tissue, may provide a partial solution to this problem. Here we review the current applications of 18F-FDG PET/CT in a variety of disease sites, including non–small cell lung cancer, head and neck cancer, and pancreatic adenocarcinoma. This review focuses on the use of 18F-FDG PET/CT to aid in planning radiotherapy and the associated benefits and challenges. We also briefly consider novel radiopharmaceuticals that are beginning to be used in the context of radiotherapy planning.

  • radiation therapy
  • IMRT
  • IGRT
  • FDG (fluorodeoxyglucose)
  • FDG PET/CT

Footnotes

  • ↵* NOTE: FOR CE CREDIT, YOU CAN ACCESS THIS ACTIVITY THROUGH THE SNM WEB SITE (http://www.snm.org/ce_online) THROUGH OCTOBER 2010.

  • No potential conflict of interest relevant to this article was reported.

  • COPYRIGHT © 2009 by the Society of Nuclear Medicine, Inc.

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Journal of Nuclear Medicine: 50 (10)
Journal of Nuclear Medicine
Vol. 50, Issue 10
October 2009
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18F-FDG PET/CT for Image-Guided and Intensity-Modulated Radiotherapy
Eric C. Ford, Joseph Herman, Ellen Yorke, Richard L. Wahl
Journal of Nuclear Medicine Oct 2009, 50 (10) 1655-1665; DOI: 10.2967/jnumed.108.055780

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18F-FDG PET/CT for Image-Guided and Intensity-Modulated Radiotherapy
Eric C. Ford, Joseph Herman, Ellen Yorke, Richard L. Wahl
Journal of Nuclear Medicine Oct 2009, 50 (10) 1655-1665; DOI: 10.2967/jnumed.108.055780
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  • Article
    • Abstract
    • PHYSICAL ISSUES
    • LUNG
    • HEAD AND NECK
    • BRAIN
    • PANCREAS
    • PARTIAL BREAST IRRADIATION
    • OTHER RADIOPHARMACEUTICALS
    • CONCLUSION
    • Footnotes
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  • Positron emission tomography imaging approaches for external beam radiation therapies: current status and future developments
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