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Journal of Nuclear Medicine

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Research ArticleCLINICAL INVESTIGATIONS

Hypometabolism Exceeds Atrophy in Presymptomatic Early-Onset Familial Alzheimer's Disease

Lisa Mosconi, Sandro Sorbi, Mony J. de Leon, Yi Li, Benedetta Nacmias, Paul S. Myoung, Wai Tsui, Andrea Ginestroni, Valentina Bessi, Mozghan Fayyazz, Paolo Caffarra and Alberto Pupi
Journal of Nuclear Medicine November 2006, 47 (11) 1778-1786;
Lisa Mosconi
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Sandro Sorbi
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Mony J. de Leon
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Yi Li
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Benedetta Nacmias
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Paul S. Myoung
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Wai Tsui
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Andrea Ginestroni
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Valentina Bessi
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Mozghan Fayyazz
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Paolo Caffarra
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Alberto Pupi
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FIGURE 1. 

FIGURE 1. 
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FIGURE 1. 

ROI drawings are displayed on coronal (A and B) and left sagittal (C and D) MR images of a representative FAD subject (FAD-1). (A) Hippocampus (1), entorhinal cortex (2), superior temporal gyrus (3). (B) Ventricles (4), whole brain (5). (C) Posterior cingulate cortex (6). (D) Inferior parietal lobe (7). Left medial temporal lobe is shown magnified in A to highlight hippocampal (1) and entorhinal cortex (2) ROIs.

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Journal of Nuclear Medicine: 66 (5)
Journal of Nuclear Medicine
Vol. 66, Issue 5
May 1, 2025
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Hypometabolism Exceeds Atrophy in Presymptomatic Early-Onset Familial Alzheimer's Disease
Lisa Mosconi, Sandro Sorbi, Mony J. de Leon, Yi Li, Benedetta Nacmias, Paul S. Myoung, Wai Tsui, Andrea Ginestroni, Valentina Bessi, Mozghan Fayyazz, Paolo Caffarra, Alberto Pupi
Journal of Nuclear Medicine Nov 2006, 47 (11) 1778-1786;

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Hypometabolism Exceeds Atrophy in Presymptomatic Early-Onset Familial Alzheimer's Disease
Lisa Mosconi, Sandro Sorbi, Mony J. de Leon, Yi Li, Benedetta Nacmias, Paul S. Myoung, Wai Tsui, Andrea Ginestroni, Valentina Bessi, Mozghan Fayyazz, Paolo Caffarra, Alberto Pupi
Journal of Nuclear Medicine Nov 2006, 47 (11) 1778-1786;
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