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OtherBasic science investigations

Crucial Role for Somatostatin Receptor Subtype 2 in Determining the Uptake of [111In-DTPA-d-Phe1]Octreotide in Somatostatin Receptor–Positive Organs

Leo J. Hofland, Steven W.J. Lamberts, P. Martin van Hagen, Jean-Claude Reubi, James Schaeffer, Marlijn Waaijers, Peter M. van Koetsveld, Ananth Srinivasan, Eric P. Krenning and Wout A.P. Breeman
Journal of Nuclear Medicine August 2003, 44 (8) 1315-1321;
Leo J. Hofland
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Steven W.J. Lamberts
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P. Martin van Hagen
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Jean-Claude Reubi
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James Schaeffer
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Marlijn Waaijers
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Peter M. van Koetsveld
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Ananth Srinivasan
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Eric P. Krenning
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Wout A.P. Breeman
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Article Information

vol. 44 no. 8 1315-1321
PubMed 
12902423

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Published online August 5, 2003.

Copyright & Usage 
THE JOURNAL OF NUCLEAR MEDICINE

Author Information

  1. Leo J. Hofland, PhD1,
  2. Steven W.J. Lamberts, PhD, MD1,
  3. P. Martin van Hagen, PhD, MD1,
  4. Jean-Claude Reubi, PhD, MD2,
  5. James Schaeffer, PhD3,
  6. Marlijn Waaijers1,
  7. Peter M. van Koetsveld1,
  8. Ananth Srinivasan, PhD4,
  9. Eric P. Krenning, PhD, MD5 and
  10. Wout A.P. Breeman, PhD5
  1. 1Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
  2. 2Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Bern, Bern, Switzerland
  3. 3Merck Laboratories, New York, New York
  4. 4Mallinckrodt Discovery, St. Louis, Missouri
  5. 5Department of Nuclear Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
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August 1, 2003
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Crucial Role for Somatostatin Receptor Subtype 2 in Determining the Uptake of [111In-DTPA-d-Phe1]Octreotide in Somatostatin Receptor–Positive Organs
Leo J. Hofland, Steven W.J. Lamberts, P. Martin van Hagen, Jean-Claude Reubi, James Schaeffer, Marlijn Waaijers, Peter M. van Koetsveld, Ananth Srinivasan, Eric P. Krenning, Wout A.P. Breeman
Journal of Nuclear Medicine Aug 2003, 44 (8) 1315-1321;

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Crucial Role for Somatostatin Receptor Subtype 2 in Determining the Uptake of [111In-DTPA-d-Phe1]Octreotide in Somatostatin Receptor–Positive Organs
Leo J. Hofland, Steven W.J. Lamberts, P. Martin van Hagen, Jean-Claude Reubi, James Schaeffer, Marlijn Waaijers, Peter M. van Koetsveld, Ananth Srinivasan, Eric P. Krenning, Wout A.P. Breeman
Journal of Nuclear Medicine Aug 2003, 44 (8) 1315-1321;
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  • Frequency and characterization of gastro-entero-pancreatic neuroendocrine tumor patients with high-grade of uptake at somatostatin receptor scintigraphy
  • Nuclear medicine techniques for the imaging and treatment of neuroendocrine tumours
  • Targeting Somatostatin Receptors: Preclinical Evaluation of Novel 18F-Fluoroethyltriazole-Tyr3-Octreotate Analogs for PET
  • Indium-111-Pentetreotide Scintigraphy and Somatostatin Receptor Subtype 2 Expression: New Prognostic Factors for Malignant Well-Differentiated Endocrine Tumors
  • Novel insights in somatostatin receptor physiology
  • The analysis of quantitative expression of somatostatin and dopamine receptors in gastro-entero-pancreatic tumours opens new therapeutic strategies
  • In Vitro and in Vivo Antitumor Effects of Cytotoxic Camptothecin-Bombesin Conjugates Are Mediated by Specific Interaction with Cellular Bombesin Receptors
  • Increased Uptake of 111In-Octreotide in Idiopathic Pulmonary Fibrosis
  • MicroPET Imaging of Gene Transfer with a Somatostatin Receptor-Based Reporter Gene and 94mTc-Demotate 1
  • The multi-ligand somatostatin analogue SOM230 inhibits ACTH secretion by cultured human corticotroph adenomas via somatostatin receptor type 5
  • Detection of Liver Metastases From Endocrine Tumors: A Prospective Comparison of Somatostatin Receptor Scintigraphy, Computed Tomography, and Magnetic Resonance Imaging
  • Induction of Apoptosis with Hybrids of Arg-Gly-Asp Molecules and Peptides and Antimitotic Effects of Hybrids of Cytostatic Drugs and Peptides
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  • Synthesis and Biologic Evaluation of Novel 18F-Labeled Probes Targeting Prostate-Specific Membrane Antigen for PET of Prostate Cancer
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