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OtherBASIC SCIENCE INVESTIGATIONS

Monte Carlo MCNP-4B–Based Absorbed Dose Distribution Estimates for Patient-Specific Dosimetry

Hélio Yoriyaz, Michael G. Stabin and Adimir dos Santos
Journal of Nuclear Medicine April 2001, 42 (4) 662-669;
Hélio Yoriyaz
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Michael G. Stabin
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Adimir dos Santos
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  • FIGURE 1.
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    FIGURE 1.

    Calculation methodology for absorbed dose distribution.

  • FIGURE 2.
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    FIGURE 2.

    Dose distribution in liver from 1.0-MeV-photon uniform source. Dose units are mGy/MBq × s.

  • FIGURE 3.
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    FIGURE 3.

    Dose distribution in kidneys from 1.0-MeV-photon uniform source. Dose units are mGy/MBq × s.

  • FIGURE 4.
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    FIGURE 4.

    Dose distribution in kidneys from 0.935-MeV-electron uniform source. Dose units are mGy/MBq × s.

  • FIGURE 5.
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    FIGURE 5.

    Dose distribution in kidneys from 0.935-MeV-electron uniform source. Dose units are mGy/MBq × s.

  • FIGURE 6.
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    FIGURE 6.

    (A) Axial slices show hypothetic lesion anatomy (red) created in liver. (B) Hypothetic nonuniform activity distribution in lesion region. (C) Regional dose distribution in lesion region and surrounding tissues caused by hypothetic nonuniform activity distribution. Dose units are mGy/MBq × s.

Tables

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    TABLE 1

    Comparison of Voxel-Based Phantom with Adult Male Phantom

    Organ or regionOrgan identification numberNumber of voxels*Voxel-based phantom mass (g)†Adult male phantom mass (g)‡
    Skin1268,68817,883.87§3,010.0
    Spinal cord32,960197.02—
    Spine514,016932.901,288.0
    Rib cage and sternum628,6851,909.27—
    Pelvis714,419959.73848.0
    Long bones87,673510.71—
    Skeletal muscle9303,00220,167.81—
    Lungs1062,3741,181.611,000.0
    Heart119,354622.60770.0
    Liver1229,2771,948.681,910.0
    Gallbladder1332921.9066.2
    Kidney147,618507.05299.0
    Esophagus1658038.60—
    Stomach175,133341.65418.0
    Small bowel1826,4471,760.31—
    Colon1918,2841,216.98—
    Pancreas2079252.7294.3
    Adrenals21624.1316.3
    Blood pool2316,4411,094.31—
    Gas (bowel)243,167210.80—
    Fluid (bowel)2552835.14—
    Bone marrow2618,6181,239.21—
    Thyroid28307.0020.7
    Trachea2939226.09—
    Spleen315,568370.61183.0
    Urine326,597439.10—
    Feces331,13475.48—
    Testes341,731115.2239.1
    Prostate3543829.15—
    Rectum371,46797.64—
    Diaphragm394,528301.38—
    Bladder403,147209.46259.0
    Lesion6391560.90—
    • ↵* Refers to voxel-based phantom model only.

    • ↵† In all organs and regions, density was 1.04 g/cm3, except that of lungs (0.296 g/cm3) and bone (1.4 g/cm3). Data from Zubal et al. (14).

    • ↵‡ Data from Cristy and Eckerman (8).

    • ↵§ Fat and muscle included.

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    TABLE 2

    Comparison of CPU Time with Number of Tallies in Head-Region Trial of Voxel-Based Phantom

    CaseNo. of talliesCPU time (min)*
    A135
    B2739
    C125162
    D1000786
    • ↵* 100,000 photon histories performed on DEC-ALPHA 3000 workstation (Digital Corp.).

    • Data from Zubal et al. (14).

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Journal of Nuclear Medicine
Vol. 42, Issue 4
April 1, 2001
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Monte Carlo MCNP-4B–Based Absorbed Dose Distribution Estimates for Patient-Specific Dosimetry
Hélio Yoriyaz, Michael G. Stabin, Adimir dos Santos
Journal of Nuclear Medicine Apr 2001, 42 (4) 662-669;

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Monte Carlo MCNP-4B–Based Absorbed Dose Distribution Estimates for Patient-Specific Dosimetry
Hélio Yoriyaz, Michael G. Stabin, Adimir dos Santos
Journal of Nuclear Medicine Apr 2001, 42 (4) 662-669;
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