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Journal of Nuclear Medicine

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About the Cover

May 1, 2018; Volume 59,Issue 5

This Month in JNM

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    This Month in JNM
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 6A;

Editor’s Page

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    Aetna and 68Ga-DOTATATE: A Sequel to “The Injustice of Being Judged by the Errors of Others” ()
    Johannes Czernin and Francesco Ceci
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 721-722;

Hot Topics

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    Radioactive Iodine Therapy for Differentiated Thyroid Cancer: Lessons from Confronting Controversial Literature on Risks for Secondary Malignancy
    Mark Tulchinsky, Ina Binse, Alfredo Campennì, Sabina Dizdarevic, Luca Giovanella, Ian Jong, Kalevi Kairemo and Chun K. Kim
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 723-725; DOI: https://doi.org/10.2967/jnumed.118.211359

The State of the Art

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    Molecular Imaging in Cancer Drug Development
    Stijn J.H. Waaijer, Iris C. Kok, Bertha Eisses, Carolina P. Schröder, Mathilde Jalving, Adrienne H. Brouwers, Marjolijn N. Lub-de Hooge and Elisabeth G.E. de Vries
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 726-732; DOI: https://doi.org/10.2967/jnumed.116.188045

Continuing Education

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    Update on 18F-Fluciclovine PET for Prostate Cancer Imaging
    Ephraim E. Parent and David M. Schuster
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 733-739; DOI: https://doi.org/10.2967/jnumed.117.204032

Focus on Molecular Imaging

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    Advanced Ultrasound Technologies for Diagnosis and Therapy
    Anne Rix, Wiltrud Lederle, Benjamin Theek, Twan Lammers, Chrit Moonen, Georg Schmitz and Fabian Kiessling
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 740-746; DOI: https://doi.org/10.2967/jnumed.117.200030

Editorial

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    PSMA-Targeted Radionuclide Therapy and Salivary Gland Toxicity: Why Does It Matter?
    David Taïeb, Jean-Marc Foletti, Manuel Bardiès, Palma Rocchi, Rodney J. Hicks and Uwe Haberkorn
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 747-748; DOI: https://doi.org/10.2967/jnumed.118.207993

Oncology

  • Clinical

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      18F-FDG–Avid Thyroid Incidentalomas: The Importance of Contextual Interpretation
      David A. Pattison, Michael Bozin, Alexandra Gorelik, Michael S. Hofman, Rodney J. Hicks and Anita Skandarajah
      Journal of Nuclear Medicine May 1, 2018, 59 (5) 749-755; DOI: https://doi.org/10.2967/jnumed.117.198085
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      Predictive Value of 18F-FDG PET in Patients with Advanced Medullary Thyroid Carcinoma Treated with Vandetanib
      Rudolf A. Werner, Jan-Stefan Schmid, Takahiro Higuchi, Mehrbod S. Javadi, Steven P. Rowe, Bruno Märkl, Christoph Aulmann, Martin Fassnacht, Matthias Kroiss, Christoph Reiners, Andreas K. Buck, Michael C. Kreissl and Constantin Lapa
      Journal of Nuclear Medicine May 1, 2018, 59 (5) 756-761; DOI: https://doi.org/10.2967/jnumed.117.199778
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      Combined 18F-Fluciclovine PET/MRI Shows Potential for Detection and Characterization of High-Risk Prostate Cancer
      Mattijs Elschot, Kirsten M. Selnæs, Elise Sandsmark, Brage Krüger-Stokke, Øystein Størkersen, Guro F. Giskeødegård, May-Britt Tessem, Siver A. Moestue, Helena Bertilsson and Tone F. Bathen
      Journal of Nuclear Medicine May 1, 2018, 59 (5) 762-768; DOI: https://doi.org/10.2967/jnumed.117.198598
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      Prediction of 90Y Radioembolization Outcome from Pretherapeutic Factors with Random Survival Forests
      Michael Ingrisch, Franziska Schöppe, Karolin Paprottka, Matthias Fabritius, Frederik F. Strobl, Enrico N. De Toni, Harun Ilhan, Andrei Todica, Marlies Michl and Philipp Marius Paprottka
      Journal of Nuclear Medicine May 1, 2018, 59 (5) 769-773; DOI: https://doi.org/10.2967/jnumed.117.200758
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      18F-FDG PET/CT in Erdheim–Chester Disease: Imaging Findings and Potential BRAF Mutation Biomarker
      Jason R. Young, Geoffrey B. Johnson, Robert C. Murphy, Ronald S. Go and Stephen M. Broski
      Journal of Nuclear Medicine May 1, 2018, 59 (5) 774-779; DOI: https://doi.org/10.2967/jnumed.117.200741

Translational

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    Digitalislike Compounds Restore hNIS Expression and Iodide Uptake Capacity in Anaplastic Thyroid Cancer
    Marika H. Tesselaar, Thomas Crezee, Imke Schuurmans, Danny Gerrits, James Nagarajah, Otto C. Boerman, Ilse van Engen–van Grunsven, Johannes W.A. Smit, Romana T. Netea–Maier and Theo S. Plantinga
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 780-786; DOI: https://doi.org/10.2967/jnumed.117.200675

Theranostics

  • Clinical

    • INVITED PERSPECTIVE

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        Molecular Imaging of Prostate Cancer: Choosing the Right Agent
        Steven P. Rowe, Martin G. Pomper and Michael A. Gorin
        Journal of Nuclear Medicine May 1, 2018, 59 (5) 787-788; DOI: https://doi.org/10.2967/jnumed.117.206318
    • You have access
      Comparison of 68Ga-PSMA-11 and 18F-Fluciclovine PET/CT in a Case Series of 10 Patients with Prostate Cancer Recurrence
      Jeremie Calais, Wolfgang P. Fendler, Ken Herrmann, Matthias Eiber and Francesco Ceci
      Journal of Nuclear Medicine May 1, 2018, 59 (5) 789-794; DOI: https://doi.org/10.2967/jnumed.117.203257
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      Targeted α-Therapy of Metastatic Castration-Resistant Prostate Cancer with 225Ac-PSMA-617: Swimmer-Plot Analysis Suggests Efficacy Regarding Duration of Tumor Control
      Clemens Kratochwil, Frank Bruchertseifer, Hendrik Rathke, Markus Hohenfellner, Frederik L. Giesel, Uwe Haberkorn and Alfred Morgenstern
      Journal of Nuclear Medicine May 1, 2018, 59 (5) 795-802; DOI: https://doi.org/10.2967/jnumed.117.203539
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      Prospective Evaluation of 68Ga-RM2 PET/MRI in Patients with Biochemical Recurrence of Prostate Cancer and Negative Findings on Conventional Imaging
      Ryogo Minamimoto, Ida Sonni, Steven Hancock, Shreyas Vasanawala, Andreas Loening, Sanjiv S. Gambhir and Andrei Iagaru
      Journal of Nuclear Medicine May 1, 2018, 59 (5) 803-808; DOI: https://doi.org/10.2967/jnumed.117.197624
    • FEATURED ARTICLE OF THE MONTH

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        177Lu-3BP-227 for Neurotensin Receptor 1–Targeted Therapy of Metastatic Pancreatic Adenocarcinoma: First Clinical Results
        Richard P. Baum, Aviral Singh, Christiane Schuchardt, Harshad R. Kulkarni, Ingo Klette, Stefan Wiessalla, Frank Osterkamp, Ulrich Reineke and Christiane Smerling
        Journal of Nuclear Medicine May 1, 2018, 59 (5) 809-814; DOI: https://doi.org/10.2967/jnumed.117.193847
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      Radiolabeled (4-Fluoro-3-Iodobenzyl)Guanidine Improves Imaging and Targeted Radionuclide Therapy of Norepinephrine Transporter–Expressing Tumors
      Aiko Yamaguchi, Hirofumi Hanaoka, Tetsuya Higuchi and Yoshito Tsushima
      Journal of Nuclear Medicine May 1, 2018, 59 (5) 815-821; DOI: https://doi.org/10.2967/jnumed.117.201525

Neurology

  • Clinical

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      Spatiotemporal Distribution of β-Amyloid in Alzheimer Disease Is the Result of Heterogeneous Regional Carrying Capacities
      Alex Whittington, David J. Sharp and Roger N. Gunn; for the Alzheimer’s Disease Neuroimaging Initiative
      Journal of Nuclear Medicine May 1, 2018, 59 (5) 822-827; DOI: https://doi.org/10.2967/jnumed.117.194720

Genitourinary

  • Basic

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      Functional Renal Imaging with 2-Deoxy-2-18F-Fluorosorbitol PET in Rat Models of Renal Disorders
      Rudolf A. Werner, Hiroshi Wakabayashi, Xinyu Chen, Mitsuru Hirano, Tetsuya Shinaji, Constantin Lapa, Steven P. Rowe, Mehrbod S. Javadi and Takahiro Higuchi
      Journal of Nuclear Medicine May 1, 2018, 59 (5) 828-832; DOI: https://doi.org/10.2967/jnumed.117.203828

Molecular Imaging

  • Basic

    • You have access
      Sex as a Biologic Variable in Preclinical Imaging Research: Initial Observations with 18F-FLT
      Szeman Ruby Chan, Kelley Salem, Justin Jeffery, Ginny L. Powers, Yongjun Yan, Kooresh I. Shoghi, Aparna M. Mahajan and Amy M. Fowler
      Journal of Nuclear Medicine May 1, 2018, 59 (5) 833-838; DOI: https://doi.org/10.2967/jnumed.117.199406

Musculoskeletal

  • Basic

    • FEATURED BASIC SCIENCE ARTICLE

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        18F-FEDAC as a Targeting Agent for Activated Macrophages in DBA/1 Mice with Collagen-Induced Arthritis: Comparison with 18F-FDG
        Seock-Jin Chung, Hai-Jeon Yoon, Hyewon Youn, Mi Jeong Kim, Yun-Sang Lee, Jae Min Jeong, June-Key Chung, Keon Wook Kang, Lin Xie, Ming-Rong Zhang and Gi Jeong Cheon
        Journal of Nuclear Medicine May 1, 2018, 59 (5) 839-845; DOI: https://doi.org/10.2967/jnumed.117.200667

Physics/Instrumentation

  • Clinical

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      Comparison of PET/CT with Sequential PET/MRI Using an MR-Compatible Mobile PET System
      Ryusuke Nakamoto, Yuji Nakamoto, Takayoshi Ishimori, Yasutaka Fushimi, Aki Kido and Kaori Togashi
      Journal of Nuclear Medicine May 1, 2018, 59 (5) 846-851; DOI: https://doi.org/10.2967/jnumed.117.197665
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      Zero-Echo-Time and Dixon Deep Pseudo-CT (ZeDD CT): Direct Generation of Pseudo-CT Images for Pelvic PET/MRI Attenuation Correction Using Deep Convolutional Neural Networks with Multiparametric MRI
      Andrew P. Leynes, Jaewon Yang, Florian Wiesinger, Sandeep S. Kaushik, Dattesh D. Shanbhag, Youngho Seo, Thomas A. Hope and Peder E.Z. Larson
      Journal of Nuclear Medicine May 1, 2018, 59 (5) 852-858; DOI: https://doi.org/10.2967/jnumed.117.198051

Erratum

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    Erratum
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 858;

Book Reviews

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    Molecular Imaging: An Introduction
    E. Edmund Kim
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 859; DOI: https://doi.org/10.2967/jnumed.118.209635

Letters to the Editor

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    Comparison of 68Ga-PSMA-11 and 18F-Fluciclovine PET/CT in a Case Series of 10 Patients with Prostate Cancer Recurrence: Interesting, but Far from Definitive
    Bela Denes and Peter Gardiner
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 860; DOI: https://doi.org/10.2967/jnumed.118.209817
  • You have access
    Reply: Comparison of 68Ga-PSMA-11 and 18F-Fluciclovine PET/CT in a Case Series of 10 Patients with Prostate Cancer Recurrence: Prospective Trial Is on Its Way
    Jeremie Calais, Wolfgang Peter Fendler, Ken Herrmann, Matthias Eiber and Francesco Ceci
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 861; DOI: https://doi.org/10.2967/jnumed.118.209965

SNMMI Newsline

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    NRC Advisory Committee on Medical Uses of Isotopes Spring Meeting
    Caitlin B. Kubler
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 7N;
  • You have access
    Reclassifying Diagnostic Radiopharmaceuticals
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 8N-10N;
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    Wessels to Be Recognized with Loevinger–Berman Award
    Roger W. Howell and George Sgouros; on behalf of the SNMMI Medical Internal Radiation Dose Committee
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 9N-10N;
  • You have access
    Fifty Years Ago in JNM
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 10N;
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    RADAR Develops New Generation of Dosimetry Phantoms
    Michael G. Stabin, Jeffry A. Siegel and X. George Xu; for the RAdiation Dose Assessment Resource Committee of the SNMMI
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 11N;
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    SNMMI Leadership Update: A Strong SNMMI
    Virginia Pappas
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 12N;
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    Newsbriefs
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 13N-14N;
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    From the Literature
    Journal of Nuclear Medicine May 1, 2018, 59 (5) 15N-18N;
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In this issue

Journal of Nuclear Medicine: 59 (5)
Journal of Nuclear Medicine
Vol. 59, Issue 5
May 1, 2018
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author

Issue highlights

  • 177Lu-3BP-227 for Neurotensin Receptor 1–Targeted Therapy of Metastatic Pancreatic Adenocarcinoma: First Clinical Results
  • 18F-FEDAC as a Targeting Agent for Activated Macrophages in DBA/1 Mice with Collagen-Induced Arthritis: Comparison with 18F-FDG
  • Molecular Imaging in Cancer Drug Development
  • Radioactive Iodine Therapy for Differentiated Thyroid Cancer: Lessons from Confronting Controversial Literature on Risks for Secondary Malignancy
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  • Theranostics
    • Clinical
      • INVITED PERSPECTIVE
      • FEATURED ARTICLE OF THE MONTH
  • Neurology
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  • Genitourinary
    • Basic
  • Molecular Imaging
    • Basic
  • Musculoskeletal
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      • FEATURED BASIC SCIENCE ARTICLE
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  • MIRD Pamphlet No. 28, Part 1: MIRDcalc—A Software Tool for Medical Internal Radiation Dosimetry
  • Absorbed Dose–Response Relationship in Patients with Gastroenteropancreatic Neuroendocrine Tumors Treated with [177Lu]Lu-DOTATATE: One Step Closer to Personalized Medicine
  • Prediction of 177Lu-DOTATATE PRRT Outcome Using Multimodality Imaging in Patients with Gastroenteropancreatic Neuroendocrine Tumors: Results from a Prospective Phase II LUMEN Study
  • Renal and Multiorgan Safety of 177Lu-PSMA-617 in Patients with Metastatic Castration-Resistant Prostate Cancer in the VISION Dosimetry Substudy
  • High-Temporal-Resolution Lung Kinetic Modeling Using Total-Body Dynamic PET with Time-Delay and Dispersion Corrections
More...
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