[123I]CC1: A PARP-Targeting, Auger Electron–Emitting Radiopharmaceutical for Radionuclide Therapy of Cancer

Chung Ying Chan; Zijun Chen; Florian Guibbal; Gemma Dias; Gianluca Destro; Edward O’Neill; Mathew Veal; Doreen Lau; Michael Mosley; Thomas C. Wilson; Véronique Gouverneur; Bart Cornelissen

doi:10.2967/jnumed.123.265429

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[¹²³I]CC1: A PARP-Targeting, Auger Electron–Emitting Radiopharmaceutical for Radionuclide Therapy of Cancer

Chung Ying Chan, Zijun Chen, Florian Guibbal, Gemma Dias, Gianluca Destro, Edward O’Neill, Mathew Veal, Doreen Lau, Michael Mosley, Thomas C. Wilson, Véronique Gouverneur and Bart Cornelissen

Journal of Nuclear Medicine September 2023, jnumed.123.265429; DOI: https://doi.org/10.2967/jnumed.123.265429

Chung Ying Chan

1MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, United Kingdom;

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Zijun Chen

2Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom; and

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Florian Guibbal

1MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, United Kingdom;

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Gemma Dias

1MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, United Kingdom;

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Gianluca Destro

1MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, United Kingdom;

2Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom; and

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Edward O’Neill

1MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, United Kingdom;

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Mathew Veal

1MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, United Kingdom;

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Doreen Lau

1MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, United Kingdom;

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Michael Mosley

1MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, United Kingdom;

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Thomas C. Wilson

2Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom; and

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Véronique Gouverneur

2Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom; and

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Bart Cornelissen

1MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, United Kingdom;

3Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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Journal of Nuclear Medicine

Vol. 66, Issue 5

May 1, 2025

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[¹²³I]CC1: A PARP-Targeting, Auger Electron–Emitting Radiopharmaceutical for Radionuclide Therapy of Cancer

Chung Ying Chan, Zijun Chen, Florian Guibbal, Gemma Dias, Gianluca Destro, Edward O’Neill, Mathew Veal, Doreen Lau, Michael Mosley, Thomas C. Wilson, Véronique Gouverneur, Bart Cornelissen

Journal of Nuclear Medicine Sep 2023, jnumed.123.265429; DOI: 10.2967/jnumed.123.265429

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[¹²³I]CC1: A PARP-Targeting, Auger Electron–Emitting Radiopharmaceutical for Radionuclide Therapy of Cancer

Chung Ying Chan, Zijun Chen, Florian Guibbal, Gemma Dias, Gianluca Destro, Edward O’Neill, Mathew Veal, Doreen Lau, Michael Mosley, Thomas C. Wilson, Véronique Gouverneur, Bart Cornelissen

Journal of Nuclear Medicine Sep 2023, jnumed.123.265429; DOI: 10.2967/jnumed.123.265429

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PARP
radionuclide therapy
radiopharmaceuticals
123I
Auger

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