Skip to main content

Main menu

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
    • Continuing Education
    • JNM Podcasts
  • Subscriptions
    • Subscribers
    • Institutional and Non-member
    • Rates
    • Journal Claims
    • Corporate & Special Sales
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI

User menu

  • Subscribe
  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Nuclear Medicine
  • SNMMI
    • JNM
    • JNMT
    • SNMMI Journals
    • SNMMI
  • Subscribe
  • My alerts
  • Log in
  • My Cart
Journal of Nuclear Medicine

Advanced Search

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • JNM Supplement
    • SNMMI Annual Meeting Abstracts
    • Continuing Education
    • JNM Podcasts
  • Subscriptions
    • Subscribers
    • Institutional and Non-member
    • Rates
    • Journal Claims
    • Corporate & Special Sales
  • Authors
    • Submit to JNM
    • Information for Authors
    • Assignment of Copyright
    • AQARA requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • View or Listen to JNM Podcast
  • Visit JNM on Facebook
  • Join JNM on LinkedIn
  • Follow JNM on Twitter
  • Subscribe to our RSS feeds
OtherBasic Science (Animal or Phantoms)

Imaging P-glycoprotein Induction at the Blood-Brain Barrier of a Beta-Amyloidosis Mouse Model with 11C-Metoclopramide PET

Viktoria Zoufal, Severin Mairinger, Mirjam Brackhan, Markus Krohn, Thomas Filip, Michael Sauberer, Johann Stanek, Thomas Wanek, Nicolas Tournier, Martin Bauer, Jens Pahnke and Oliver Langer
Journal of Nuclear Medicine December 2019, jnumed.119.237198; DOI: https://doi.org/10.2967/jnumed.119.237198
Viktoria Zoufal
1 AIT Austrian Institute of Technology GmbH, Austria;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Severin Mairinger
1 AIT Austrian Institute of Technology GmbH, Austria;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mirjam Brackhan
2 University of Oslo, Norway;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Markus Krohn
2 University of Oslo, Norway;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Thomas Filip
1 AIT Austrian Institute of Technology GmbH, Austria;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michael Sauberer
1 AIT Austrian Institute of Technology GmbH, Austria;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Johann Stanek
1 AIT Austrian Institute of Technology GmbH, Austria;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Thomas Wanek
1 AIT Austrian Institute of Technology GmbH, Austria;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nicolas Tournier
3 CEA-SHFJ, France;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Martin Bauer
4 Medical University of Vienna, Austria
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jens Pahnke
2 University of Oslo, Norway;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Oliver Langer
1 AIT Austrian Institute of Technology GmbH, Austria;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Oliver Langer
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • PDF
Loading

Article Information

jnumed.119.237198
DOI 
https://doi.org/10.2967/jnumed.119.237198
PubMed 
31806767

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Published online December 5, 2019.

Article Versions

  • You are currently viewing a previous version of this article (December 5, 2019 - 10:37).
  • View the most recent version of this article
Copyright & Usage 
Copyright © 2019 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Author Information

  1. Viktoria Zoufal1,
  2. Severin Mairinger1,
  3. Mirjam Brackhan2,
  4. Markus Krohn2,
  5. Thomas Filip1,
  6. Michael Sauberer1,
  7. Johann Stanek1,
  8. Thomas Wanek1,
  9. Nicolas Tournier3,
  10. Martin Bauer4,
  11. Jens Pahnke2 and
  12. Oliver Langer1
  1. 1 AIT Austrian Institute of Technology GmbH, Austria;
  2. 2 University of Oslo, Norway;
  3. 3 CEA-SHFJ, France;
  4. 4 Medical University of Vienna, Austria
  1. For correspondence or reprints contact: Oliver Langer, AIT Austrian Institute of Technology GmbH, Seibersdorf 2444, Austria. E-mail: oliver.langer@ait.ac.at

Statistics from Altmetric.com

Cited By...

  • 26 Citations
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Relationship Between Amyloid-β Deposition and Blood–Brain Barrier Dysfunction in Alzheimer’s Disease
    Dong Wang, Fanglian Chen, Zhaoli Han, Zhenyu Yin, Xintong Ge, Ping Lei
    Frontiers in Cellular Neuroscience 2021 15
  • Comparative vulnerability of PET radioligands to partial inhibition of P-glycoprotein at the blood-brain barrier: A criterion of choice?
    Louise Breuil, Solène Marie, Sébastien Goutal, Sylvain Auvity, Charles Truillet, Wadad Saba, Oliver Langer, Fabien Caillé, Nicolas Tournier
    Journal of Cerebral Blood Flow & Metabolism 2022 42 1
  • Discerning the Role of Blood Brain Barrier Dysfunction in Alzheimer’s Disease
    Qing-Qing Tao, Rong-Rong Lin, Yi-He Chen, Zhi-Ying Wu
    Aging and disease 2022 13 5
  • Positron Emission Tomography in Animal Models of Alzheimer’s Disease Amyloidosis: Translational Implications
    Ruiqing Ni
    Pharmaceuticals 2021 14 11
  • Vascular endothelial cells: a fundamental approach for brain waste clearance
    Huimin Wei, Huimin Jiang, Yifan Zhou, Xuechun Xiao, Chen Zhou, Xunming Ji
    Brain 2023 146 4
  • Vesicular ATP-binding cassette transporters in human disease: relevant aspects of their organization for future drug development
    Katja Stefan, Lionel Yi Wen Leck, Vigneshwaran Namasivayam, Pablo Bascuñana, Michael Li-Hsuan Huang, Patrick Johannes Riss, Jens Pahnke, Patric Jan Jansson, Sven Marcel Stefan
    Future Drug Discovery 2020 2 4
  • Automated synthesis, preclinical toxicity, and radiation dosimetry of [18F]MC225 for clinical use: a tracer for measuring P-glycoprotein function at the blood-brain barrier
    Jun Toyohara, Muneyuki Sakata, Tetsuro Tago, Nicola A. Colabufo, Gert Luurtsema
    EJNMMI Research 2020 10 1
  • Brain Distribution of Dual ABCB1/ABCG2 Substrates Is Unaltered in a Beta-Amyloidosis Mouse Model
    Thomas Wanek, Viktoria Zoufal, Mirjam Brackhan, Markus Krohn, Severin Mairinger, Thomas Filip, Michael Sauberer, Johann Stanek, Thomas Pekar, Jens Pahnke, Oliver Langer
    International Journal of Molecular Sciences 2020 21 21
  • Impact of Cytochrome Induction or Inhibition on the Plasma and Brain Kinetics of [11C]metoclopramide, a PET Probe for P-Glycoprotein Function at the Blood-Brain Barrier
    Louise Breuil, Nora Ziani, Sarah Leterrier, Gaëlle Hugon, Fabien Caillé, Viviane Bouilleret, Charles Truillet, Maud Goislard, Myriam El Biali, Martin Bauer, Oliver Langer, Sébastien Goutal, Nicolas Tournier
    Pharmaceutics 2022 14 12
  • Cell-Penetrating Peptides-Mediated Therapeutic Agents Delivery into the Central Nervous System
    Yuanyuan Wei, Hongying Bao, Le Wang, Yi Cao, Zhusheng Liu, Xueli Zhu, Tianxiang Chen, Aiguo Wu, Juan Li
    ACS Materials Letters 2024 6 6

Article usage

Article usage: December 2019 to April 2025

AbstractFullPdf
Dec 2019414032
Jan 2020145015
Feb 2020113019
Mar 202075013
Apr 20209805
May 202062011
Jun 202052024
Jul 2020573746
Aug 2020334210
Sep 2020137327
Oct 202011519
Nov 202053614
Dec 202084614
Jan 2021493239
Feb 2021392426
Mar 2021181619
Apr 2021332119
May 2021193023
Jun 2021191415
Jul 2021222220
Aug 2021192921
Sep 2021171418
Oct 2021181220
Nov 2021152737
Dec 2021203118
Jan 2022221311
Feb 2022201510
Mar 2022182015
Apr 2022111911
May 2022113531
Jun 202272115
Jul 202272816
Aug 202242411
Sep 2022146116
Oct 20229169
Nov 202251513
Dec 202232011
Jan 2023264313
Feb 202361816
Mar 202385213
Apr 202371811
May 2023132717
Jun 2023234115
Jul 202351818
Aug 2023181512
Sep 2023101616
Oct 2023142011
Nov 2023102014
Dec 202341910
Jan 2024223214
Feb 2024151610
Mar 202472530
Apr 20242020130
May 20246299
Jun 2024143024
Jul 2024232326
Aug 20244127206
Sep 20243023113
Oct 2024113515
Nov 2024182118
Dec 20242209
Jan 2025232126
Feb 2025188618
Mar 2025134025
Apr 2025173335
PreviousNext
Back to top

In this issue

Journal of Nuclear Medicine: 66 (5)
Journal of Nuclear Medicine
Vol. 66, Issue 5
May 1, 2025
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Complete Issue (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on Journal of Nuclear Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Imaging P-glycoprotein Induction at the Blood-Brain Barrier of a Beta-Amyloidosis Mouse Model with 11C-Metoclopramide PET
(Your Name) has sent you a message from Journal of Nuclear Medicine
(Your Name) thought you would like to see the Journal of Nuclear Medicine web site.
Citation Tools
Imaging P-glycoprotein Induction at the Blood-Brain Barrier of a Beta-Amyloidosis Mouse Model with 11C-Metoclopramide PET
Viktoria Zoufal, Severin Mairinger, Mirjam Brackhan, Markus Krohn, Thomas Filip, Michael Sauberer, Johann Stanek, Thomas Wanek, Nicolas Tournier, Martin Bauer, Jens Pahnke, Oliver Langer
Journal of Nuclear Medicine Dec 2019, jnumed.119.237198; DOI: 10.2967/jnumed.119.237198

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Imaging P-glycoprotein Induction at the Blood-Brain Barrier of a Beta-Amyloidosis Mouse Model with 11C-Metoclopramide PET
Viktoria Zoufal, Severin Mairinger, Mirjam Brackhan, Markus Krohn, Thomas Filip, Michael Sauberer, Johann Stanek, Thomas Wanek, Nicolas Tournier, Martin Bauer, Jens Pahnke, Oliver Langer
Journal of Nuclear Medicine Dec 2019, jnumed.119.237198; DOI: 10.2967/jnumed.119.237198
Twitter logo Facebook logo LinkedIn logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • PDF

Related Articles

  • This Month in JNM
  • PubMed
  • Google Scholar

Cited By...

  • Imaging the Activity of Efflux Transporters at the Blood-Brain Barrier in Neurologic Diseases: Radiotracer Selection Criteria
  • Google Scholar

Similar Articles

Keywords

  • Animal Imaging
  • Neurology
  • PET
  • 11C-metoclopramide
  • APP/PS1-21 mice
  • Alzheimer disease
  • P-glycoprotein induction
  • beta-amyloid clearance
SNMMI

© 2025 SNMMI

Powered by HighWire