Interreader and Intrareader Reproducibility of 18F-Flotufolastat Image Interpretation in Patients with Newly Diagnosed or Recurrent Prostate Cancer: Data from Two Phase 3 Prospective Multicenter Studies

Phillip H. Kuo; Giuseppe Esposito; Gary A. Ulaner; Don Yoo; Katherine Zukotynski; Gregory C. Ravizzini; Ross Penny; Matthew P. Miller; Albert Chau; Phillip Davis; Brian F. Chapin; David M. Schuster; on behalf of the SPOTLIGHT and LIGHTHOUSE study groups

doi:10.2967/jnumed.123.267306

Research ArticleClinical Investigation

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Interreader and Intrareader Reproducibility of ¹⁸F-Flotufolastat Image Interpretation in Patients with Newly Diagnosed or Recurrent Prostate Cancer: Data from Two Phase 3 Prospective Multicenter Studies

Phillip H. Kuo, Giuseppe Esposito, Gary A. Ulaner, Don Yoo, Katherine Zukotynski, Gregory C. Ravizzini, Ross Penny, Matthew P. Miller, Albert Chau, Phillip Davis, Brian F. Chapin, David M. Schuster and on behalf of the SPOTLIGHT and LIGHTHOUSE study groups

Journal of Nuclear Medicine August 2024, 65 (8) 1239-1243; DOI: https://doi.org/10.2967/jnumed.123.267306

Phillip H. Kuo

1Departments of Medical Imaging, Medicine, and Biomedical Engineering, University of Arizona, Tucson, Arizona;

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Giuseppe Esposito

2Department of Nuclear Medicine, Medstar Georgetown University Hospital, Washington, District of Columbia;

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Gary A. Ulaner

3Department of Molecular Imaging and Therapy, Hoag Family Cancer Institute, Irvine, California;

4Radiology and Translational Genomics, University of Southern California, Los Angeles, California;

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Don Yoo

5Warren Alpert Medical School of Brown University, Providence, Rhode Island;

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Katherine Zukotynski

6Department of Radiology, McMaster University, Hamilton, Ontario, Canada;

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Gregory C. Ravizzini

7Division of Diagnostic Imaging, Department of Nuclear Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas;

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Ross Penny

8Blue Earth Diagnostics Ltd., Oxford, United Kingdom;

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Matthew P. Miller

8Blue Earth Diagnostics Ltd., Oxford, United Kingdom;

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Albert Chau

8Blue Earth Diagnostics Ltd., Oxford, United Kingdom;

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Phillip Davis

9Blue Earth Diagnostics Inc., Monroe Township, New Jersey;

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Brian F. Chapin

10Department of Urology, University of Texas MD Anderson Cancer Center, Houston, Texas; and

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David M. Schuster

11Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, Georgia

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Journal of Nuclear Medicine

Vol. 65, Issue 8

August 1, 2024

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Interreader and Intrareader Reproducibility of ¹⁸F-Flotufolastat Image Interpretation in Patients with Newly Diagnosed or Recurrent Prostate Cancer: Data from Two Phase 3 Prospective Multicenter Studies

Phillip H. Kuo, Giuseppe Esposito, Gary A. Ulaner, Don Yoo, Katherine Zukotynski, Gregory C. Ravizzini, Ross Penny, Matthew P. Miller, Albert Chau, Phillip Davis, Brian F. Chapin, David M. Schuster, on behalf of the SPOTLIGHT and LIGHTHOUSE study groups

Journal of Nuclear Medicine Aug 2024, 65 (8) 1239-1243; DOI: 10.2967/jnumed.123.267306

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Phillip H. Kuo, Giuseppe Esposito, Gary A. Ulaner, Don Yoo, Katherine Zukotynski, Gregory C. Ravizzini, Ross Penny, Matthew P. Miller, Albert Chau, Phillip Davis, Brian F. Chapin, David M. Schuster, on behalf of the SPOTLIGHT and LIGHTHOUSE study groups

Journal of Nuclear Medicine Aug 2024, 65 (8) 1239-1243; DOI: 10.2967/jnumed.123.267306

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Molecular imaging
oncology
PET/CT
PSMA
interreader variability

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Interreader and Intrareader Reproducibility of ¹⁸F-Flotufolastat Image Interpretation in Patients with Newly Diagnosed or Recurrent Prostate Cancer: Data from Two Phase 3 Prospective Multicenter Studies

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