Research ArticleBasic Science Investigation
Open Access
Signaling Network Response to α-Particle–Targeted Therapy with the 225Ac-Labeled Minigastrin Analog 225Ac-PP-F11N Reveals the Radiosensitizing Potential of Histone Deacetylase Inhibitors
Yun Qin, Stefan Imobersteg, Stephan Frank, Alain Blanc, Tanja Chiorazzo, Philipp Berger, Roger Schibli, Martin P. Béhé and Michal Grzmil
Journal of Nuclear Medicine June 2023, 64 (6) 873-879; DOI: https://doi.org/10.2967/jnumed.122.264597
Yun Qin
1Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, Villigen, Switzerland;
2Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland;
Stefan Imobersteg
1Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, Villigen, Switzerland;
Stephan Frank
3Division of Neuropathology, Institute of Pathology, University of Basel, Basel, Switzerland; and
Alain Blanc
1Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, Villigen, Switzerland;
Tanja Chiorazzo
1Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, Villigen, Switzerland;
Philipp Berger
4Laboratory of Nanoscale Biology, Paul Scherrer Institute, Villigen, Switzerland
Roger Schibli
1Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, Villigen, Switzerland;
2Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland;
Martin P. Béhé
1Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, Villigen, Switzerland;
Michal Grzmil
1Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, Villigen, Switzerland;

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Journal of Nuclear Medicine
Vol. 64, Issue 6
June 1, 2023
Signaling Network Response to α-Particle–Targeted Therapy with the 225Ac-Labeled Minigastrin Analog 225Ac-PP-F11N Reveals the Radiosensitizing Potential of Histone Deacetylase Inhibitors
Yun Qin, Stefan Imobersteg, Stephan Frank, Alain Blanc, Tanja Chiorazzo, Philipp Berger, Roger Schibli, Martin P. Béhé, Michal Grzmil
Journal of Nuclear Medicine Jun 2023, 64 (6) 873-879; DOI: 10.2967/jnumed.122.264597
Signaling Network Response to α-Particle–Targeted Therapy with the 225Ac-Labeled Minigastrin Analog 225Ac-PP-F11N Reveals the Radiosensitizing Potential of Histone Deacetylase Inhibitors
Yun Qin, Stefan Imobersteg, Stephan Frank, Alain Blanc, Tanja Chiorazzo, Philipp Berger, Roger Schibli, Martin P. Béhé, Michal Grzmil
Journal of Nuclear Medicine Jun 2023, 64 (6) 873-879; DOI: 10.2967/jnumed.122.264597
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