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Research ArticleBasic Science Investigation
Open Access

Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain

Brendon E. Cook, Sangram Nag, Ryosuke Arakawa, Edward Yin-Shiang Lin, Nancy Stratman, Kevin Guckian, Heike Hering, Mukesh Lulla, Jinkuk Choi, Cristian Salinas, Nathan E. Genung, Anton Forsberg Morén, Martin Bolin, Giulia Boscutti, Christophe Plisson, Laurent Martarello, Christer Halldin and Maciej A. Kaliszczak
Journal of Nuclear Medicine October 2023, 64 (10) 1588-1593; DOI: https://doi.org/10.2967/jnumed.122.265225
Brendon E. Cook
1Biogen, Cambridge, Massachusetts;
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Sangram Nag
2Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden;
3Stockholm County Council, Stockholm, Sweden; and
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Ryosuke Arakawa
2Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden;
3Stockholm County Council, Stockholm, Sweden; and
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Edward Yin-Shiang Lin
1Biogen, Cambridge, Massachusetts;
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Nancy Stratman
1Biogen, Cambridge, Massachusetts;
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Kevin Guckian
1Biogen, Cambridge, Massachusetts;
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Heike Hering
1Biogen, Cambridge, Massachusetts;
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Mukesh Lulla
1Biogen, Cambridge, Massachusetts;
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Jinkuk Choi
1Biogen, Cambridge, Massachusetts;
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Cristian Salinas
1Biogen, Cambridge, Massachusetts;
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Nathan E. Genung
1Biogen, Cambridge, Massachusetts;
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Anton Forsberg Morén
2Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden;
3Stockholm County Council, Stockholm, Sweden; and
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Martin Bolin
2Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden;
3Stockholm County Council, Stockholm, Sweden; and
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Giulia Boscutti
4Invicro, London, United Kingdom
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Christophe Plisson
4Invicro, London, United Kingdom
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Laurent Martarello
1Biogen, Cambridge, Massachusetts;
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Christer Halldin
2Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden;
3Stockholm County Council, Stockholm, Sweden; and
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Maciej A. Kaliszczak
1Biogen, Cambridge, Massachusetts;
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Article Information

vol. 64 no. 10 1588-1593
DOI 
https://doi.org/10.2967/jnumed.122.265225
PubMed 
37934021

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication February 22, 2023
  • Revision received May 31, 2023
  • Published online October 3, 2023.

Article Versions

  • previous version (July 6, 2023 - 07:58).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2023 by the Society of Nuclear Medicine and Molecular Imaging. Immediate Open Access: Creative Commons Attribution 4.0 International License (CC BY) allows users to share and adapt with attribution, excluding materials credited to previous publications. License: https://creativecommons.org/licenses/by/4.0/. Details: http://jnm.snmjournals.org/site/misc/permission.xhtml.

Author Information

  1. Brendon E. Cook1,
  2. Sangram Nag2,3,
  3. Ryosuke Arakawa2,3,
  4. Edward Yin-Shiang Lin1,
  5. Nancy Stratman1,
  6. Kevin Guckian1,
  7. Heike Hering1,
  8. Mukesh Lulla1,
  9. Jinkuk Choi1,
  10. Cristian Salinas1,
  11. Nathan E. Genung1,
  12. Anton Forsberg Morén2,3,
  13. Martin Bolin2,3,
  14. Giulia Boscutti4,
  15. Christophe Plisson4,
  16. Laurent Martarello1,
  17. Christer Halldin2,3 and
  18. Maciej A. Kaliszczak1
  1. 1Biogen, Cambridge, Massachusetts;
  2. 2Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden;
  3. 3Stockholm County Council, Stockholm, Sweden; and
  4. 4Invicro, London, United Kingdom
  1. For correspondence or reprints, contact Maciej Kaliszczak (maciej.kaliszczak{at}biogen.com).
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Journal of Nuclear Medicine: 64 (10)
Journal of Nuclear Medicine
Vol. 64, Issue 10
October 1, 2023
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Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain
Brendon E. Cook, Sangram Nag, Ryosuke Arakawa, Edward Yin-Shiang Lin, Nancy Stratman, Kevin Guckian, Heike Hering, Mukesh Lulla, Jinkuk Choi, Cristian Salinas, Nathan E. Genung, Anton Forsberg Morén, Martin Bolin, Giulia Boscutti, Christophe Plisson, Laurent Martarello, Christer Halldin, Maciej A. Kaliszczak
Journal of Nuclear Medicine Oct 2023, 64 (10) 1588-1593; DOI: 10.2967/jnumed.122.265225

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Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain
Brendon E. Cook, Sangram Nag, Ryosuke Arakawa, Edward Yin-Shiang Lin, Nancy Stratman, Kevin Guckian, Heike Hering, Mukesh Lulla, Jinkuk Choi, Cristian Salinas, Nathan E. Genung, Anton Forsberg Morén, Martin Bolin, Giulia Boscutti, Christophe Plisson, Laurent Martarello, Christer Halldin, Maciej A. Kaliszczak
Journal of Nuclear Medicine Oct 2023, 64 (10) 1588-1593; DOI: 10.2967/jnumed.122.265225
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