Journal of Nuclear Medicine: 63 (9)

September 1, 2022; Volume 63,Issue 9

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine September 1, 2022, 63 (9) 8A;

Discussions with Leaders

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A Life in Nuclear Medicine in Israel
Ora Israel and Johannes Czernin

Journal of Nuclear Medicine September 1, 2022, 63 (9) 1285-1287; DOI: https://doi.org/10.2967/jnumed.122.264711

The State of the Art

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Nuclear Medicine and Artificial Intelligence: Best Practices for Evaluation (the RELAINCE Guidelines)
Abhinav K. Jha, Tyler J. Bradshaw, Irène Buvat, Mathieu Hatt, Prabhat KC, Chi Liu, Nancy F. Obuchowski, Babak Saboury, Piotr J. Slomka, John J. Sunderland, Richard L. Wahl, Zitong Yu, Sven Zuehlsdorff, Arman Rahmim and Ronald Boellaard

Journal of Nuclear Medicine September 1, 2022, 63 (9) 1288-1299; DOI: https://doi.org/10.2967/jnumed.121.263239

Hot Topics

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Choice Is Good at Times: The Emergence of [⁶⁴Cu]Cu-DOTATATE–Based Somatostatin Receptor Imaging in the Era of [⁶⁸Ga]Ga-DOTATATE
Abhishek Jha, Mayank Patel, Jorge A. Carrasquillo, Clara C. Chen, Corina Millo, Roberto Maass-Moreno, Alexander Ling, Frank I. Lin, Ronald M. Lechan, Thomas A. Hope, David Taïeb, Ali Cahid Civelek and Karel Pacak

Journal of Nuclear Medicine September 1, 2022, 63 (9) 1300-1301; DOI: https://doi.org/10.2967/jnumed.122.264183

Continuing Education

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Pretargeting: A Path Forward for Radioimmunotherapy
Sarah M. Cheal, Sebastian K. Chung, Brett A. Vaughn, Nai-Kong V. Cheung and Steven M. Larson

Journal of Nuclear Medicine September 1, 2022, 63 (9) 1302-1315; DOI: https://doi.org/10.2967/jnumed.121.262186

Focus on Molecular Imaging

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Antibody Engineering for Nuclear Imaging and Radioimmunotherapy
Cindy Rodriguez, Samantha Delaney, Samantha M. Sarrett, Outi M. Keinänen and Brian M. Zeglis

Journal of Nuclear Medicine September 1, 2022, 63 (9) 1316-1322; DOI: https://doi.org/10.2967/jnumed.122.263861

Editorial

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Radionuclide Evaluation of Brain Death in the Post-McMath Era: Epilogue and Enigmata
Lionel S. Zuckier

Journal of Nuclear Medicine September 1, 2022, 63 (9) 1323-1325; DOI: https://doi.org/10.2967/jnumed.122.263972

Theranostics

Clinical
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  Targeted α-Emitter Therapy with ²¹²Pb-DOTAMTATE for the Treatment of Metastatic SSTR-Expressing Neuroendocrine Tumors: First-in-Humans Dose-Escalation Clinical Trial
  Ebrahim S. Delpassand, Izabela Tworowska, Rouzbeh Esfandiari, Julien Torgue, Jason Hurt, Afshin Shafie and Rodolfo Núñez
  
  Journal of Nuclear Medicine September 1, 2022, 63 (9) 1326-1333; DOI: https://doi.org/10.2967/jnumed.121.263230
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  Utility of ¹⁸F-rhPSMA-7.3 PET for Imaging of Primary Prostate Cancer and Preoperative Efficacy in N-Staging of Unfavorable Intermediate- to Very High-Risk Patients Validated by Histopathology
  Thomas Langbein, Hui Wang, Isabel Rauscher, Markus Kroenke, Karina Knorr, Alexander Wurzer, Kristina Schwamborn, Tobias Maurer, Thomas Horn, Bernhard Haller, Hans-Jürgen Wester and Matthias Eiber
  
  Journal of Nuclear Medicine September 1, 2022, 63 (9) 1334-1342; DOI: https://doi.org/10.2967/jnumed.121.263440
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  Changes in Management After ¹⁸F-DCFPyL PSMA PET in Patients Undergoing Postprostatectomy Radiotherapy, with Early Biochemical Response Outcomes
  Michael Ng, Mario Guerrieri, Lih Ming Wong, Kim Taubman, Tom Sutherland, Angela Benson, Graeme Byrne, Sam Koschel, Kelvin Yap, Michelle Starmans, Grace Ong, Craig Macleod, Marcus Foo and Michael Chao
  
  Journal of Nuclear Medicine September 1, 2022, 63 (9) 1343-1348; DOI: https://doi.org/10.2967/jnumed.121.263521
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  Radiation Protection and Occupational Exposure on ⁶⁸Ga-PSMA-11–Based Cerenkov Luminescence Imaging Procedures in Robot-Assisted Prostatectomy
  Pedro Fragoso Costa, Wolfgang P. Fendler, Ken Herrmann, Patrick Sandach, Hong Grafe, Maarten R. Grootendorst, Lukas Püllen, Claudia Kesch, Ulrich Krafft, Jan P. Radtke, Stephan Tschirdewahn, Boris A. Hadaschik and Christopher Darr
  
  Journal of Nuclear Medicine September 1, 2022, 63 (9) 1349-1356; DOI: https://doi.org/10.2967/jnumed.121.263175
Basic
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  Administration Routes for SSTR-/PSMA- and FAP-Directed Theranostic Radioligands in Mice
  Jasmin M. Klose, Jasmin Wosniack, Janette Iking, Magdalena Staniszewska, Fadi Zarrad, Marija Trajkovic-Arsic, Ken Herrmann, Pedro Fragoso Costa, Katharina Lueckerath and Wolfgang P. Fendler
  
  Journal of Nuclear Medicine September 1, 2022, 63 (9) 1357-1363; DOI: https://doi.org/10.2967/jnumed.121.263453
- FEATURED BASIC SCIENCE ARTICLE
  - Open Access
    Substitution of l-Tryptophan by α-Methyl-l-Tryptophan in ¹⁷⁷Lu-RM2 Results in ¹⁷⁷Lu-AMTG, a High-Affinity Gastrin-Releasing Peptide Receptor Ligand with Improved In Vivo Stability
    Thomas Günther, Sandra Deiser, Veronika Felber, Roswitha Beck and Hans-Jürgen Wester
    
    Journal of Nuclear Medicine September 1, 2022, 63 (9) 1364-1370; DOI: https://doi.org/10.2967/jnumed.121.263323

Oncology

Clinical
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  Prospective Phase II Trial of Prognostication by ⁶⁸Ga-NOTA-AE105 uPAR PET in Patients with Neuroendocrine Neoplasms: Implications for uPAR-Targeted Therapy
  Esben Andreas Carlsen, Mathias Loft, Annika Loft, Anne Kiil Berthelsen, Seppo W. Langer, Ulrich Knigge and Andreas Kjaer
  
  Journal of Nuclear Medicine September 1, 2022, 63 (9) 1371-1377; DOI: https://doi.org/10.2967/jnumed.121.263177
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  ¹⁸F-FDG PET/CT–Based Prognostic Survival Model After Surgery for Head and Neck Cancer
  Gwenaelle Creff, Franck Jegoux, Xavier Palard, Adrien Depeursinge, Ronan Abgral, Remi Marianowski, Jean-Christophe Leclere, Thomas Eugene, Olivier Malard, Renaud De Crevoisier, Anne Devillers and Joel Castelli
  
  Journal of Nuclear Medicine September 1, 2022, 63 (9) 1378-1385; DOI: https://doi.org/10.2967/jnumed.121.262891
Translational
- Open Access
  Interrogating Glioma-Associated Microglia and Macrophage Dynamics Under CSF-1R Therapy with Multitracer In Vivo PET/MRI
  Claudia Foray, Cristina Barca, Alexandra Winkeler, Stefan Wagner, Sven Hermann, Michael Schäfers, Oliver M. Grauer, Bastian Zinnhardt and Andreas H. Jacobs
  
  Journal of Nuclear Medicine September 1, 2022, 63 (9) 1386-1393; DOI: https://doi.org/10.2967/jnumed.121.263318
Basic
- Open Access
  ⁶⁸Ga-DOTA-NT-20.3 Neurotensin Receptor 1 PET Imaging as a Surrogate for Neuroendocrine Differentiation of Prostate Cancer
  Wenyu Wu, Fei Yu, Pengjun Zhang, Ting Bu, Jingjing Fu, Shuyue Ai, Qinqin You, Liang Shi, Guoqiang Shao, Feng Wang, Marina Hodolic and Hongqian Guo
  
  Journal of Nuclear Medicine September 1, 2022, 63 (9) 1394-1400; DOI: https://doi.org/10.2967/jnumed.121.263132
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  Molecular Imaging of Neuroendocrine Prostate Cancer by Targeting Delta-Like Ligand 3
  Joshua A. Korsen, Teja M. Kalidindi, Samantha Khitrov, Zachary V. Samuels, Goutam Chakraborty, Julia A. Gutierrez, John T. Poirier, Charles M. Rudin, Yu Chen, Michael J. Morris, Nagavarakishore Pillarsetty and Jason S. Lewis
  
  Journal of Nuclear Medicine September 1, 2022, 63 (9) 1401-1407; DOI: https://doi.org/10.2967/jnumed.121.263221

Neurology

Basic
- Open Access
  Short-Term Colony-Stimulating Factor 1 Receptor Inhibition–Induced Repopulation After Stroke Assessed by Longitudinal ¹⁸F-DPA-714 PET Imaging
  Cristina Barca, Amanda J. Kiliaan, Lydia Wachsmuth, Claudia Foray, Sven Hermann, Cornelius Faber, Michael Schäfers, Maximilian Wiesmann, Bastian Zinnhardt and Andreas H. Jacobs
  
  Journal of Nuclear Medicine September 1, 2022, 63 (9) 1408-1414; DOI: https://doi.org/10.2967/jnumed.121.263004

Cardiovascular

Clinical
- FEATURED ARTICLE OF THE MONTH
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    Cardiac Fibroblast Activation in Patients Early After Acute Myocardial Infarction: Integration with MR Tissue Characterization and Subsequent Functional Outcome
    Johanna Diekmann, Tobias Koenig, James T. Thackeray, Thorsten Derlin, Christoph Czerner, Jonas Neuser, Tobias L. Ross, Andreas Schäfer, Jochen Tillmanns, Johann Bauersachs and Frank M. Bengel
    
    Journal of Nuclear Medicine September 1, 2022, 63 (9) 1415-1423; DOI: https://doi.org/10.2967/jnumed.121.263555

AI/Advanced Image Analysis

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The Impact of Semiautomatic Segmentation Methods on Metabolic Tumor Volume, Intensity, and Dissemination Radiomics in ¹⁸F-FDG PET Scans of Patients with Classical Hodgkin Lymphoma
Julia Driessen, Gerben J.C. Zwezerijnen, Heiko Schöder, Esther E.E. Drees, Marie José Kersten, Alison J. Moskowitz, Craig H. Moskowitz, Jakoba J. Eertink, Henrica C.W. de Vet, Otto S. Hoekstra, Josée M. Zijlstra and Ronald Boellaard

Journal of Nuclear Medicine September 1, 2022, 63 (9) 1424-1430; DOI: https://doi.org/10.2967/jnumed.121.263067

Endocrinology

Clinical
- Invited Perspective
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    ¹⁸F-FDG Uptake in Brown Adipose Tissue After Exposure to the Cold: From Possible Pitfall in Early PET Scans to Metabolic Biomarker
    Paola A. Erba, Andrea Natali, H. William Strauss and Giuliano Mariani
    
    Journal of Nuclear Medicine September 1, 2022, 63 (9) 1431-1432; DOI: https://doi.org/10.2967/jnumed.122.264188
  - You have access
    Brown Adipose Tissue: A Protective Mechanism Against “Preprediabetes”?
    John P. Crandall, Tyler J. Fraum and Richard L. Wahl
    
    Journal of Nuclear Medicine September 1, 2022, 63 (9) 1433-1440; DOI: https://doi.org/10.2967/jnumed.121.263357

Radiobiology/Dosimetry

Special Contribution
- Open Access
  MIRD Pamphlet No. 27: MIRDcell V3, a Revised Software Tool for Multicellular Dosimetry and Bioeffect Modeling
  Sumudu Katugampola, Jianchao Wang, Alex Rosen and Roger W. Howell
  
  Journal of Nuclear Medicine September 1, 2022, 63 (9) 1441-1449; DOI: https://doi.org/10.2967/jnumed.121.263253

The Illustrated Post

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Antibody-Guided Molecular Imaging of Aspergillus Lung Infections in Leukemia Patients
Johannes Schwenck, Andreas Maurer, Nicolas Beziere, Francesco Fiz, Frederic Boschetti, Susanne Geistlich, Dominik Seyfried, Matthias Gunzer, Gerald Reischl, Jöri Wehrmüller, Walter Ehrlichmann, Marius Horger, Sergios Gatidis, Genna Davies, Wichard Vogel, Christian la Fougère, Bernd Pichler and Christopher Thornton

Journal of Nuclear Medicine September 1, 2022, 63 (9) 1450-1451; DOI: https://doi.org/10.2967/jnumed.121.263251

Letters to the Editor

Open Access
Brain Metabolic PET Findings on the Long-Term Effects of COVID-19
Eric Guedj and Tatiana Horowitz

Journal of Nuclear Medicine September 1, 2022, 63 (9) 1452-1453; DOI: https://doi.org/10.2967/jnumed.122.264179

SNMMI Newsline

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SNMMI Newsline
Journal of Nuclear Medicine September 1, 2022, 63 (9) 11N-22N;
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SNMMI Honors Contributors, Recognizes Scientific Excellence at 2022 Annual Meeting
Journal of Nuclear Medicine September 1, 2022, 63 (9) 11N-13N;
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Full Steam Ahead for Nuclear Medicine Therapy
Munir Ghesani

Journal of Nuclear Medicine September 1, 2022, 63 (9) 14N;
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NewsBriefs
Journal of Nuclear Medicine September 1, 2022, 63 (9) 16N-18N;
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From the Literature
Journal of Nuclear Medicine September 1, 2022, 63 (9) 19N-22N;

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Table of Contents

This Month in JNM

Discussions with Leaders

The State of the Art

Hot Topics

Continuing Education

Focus on Molecular Imaging

Editorial

Theranostics

Clinical

Basic

FEATURED BASIC SCIENCE ARTICLE

Oncology

Clinical

Translational

Basic

Neurology

Basic

Cardiovascular

Clinical

FEATURED ARTICLE OF THE MONTH

AI/Advanced Image Analysis

Endocrinology

Clinical

Invited Perspective

Radiobiology/Dosimetry

Special Contribution

The Illustrated Post

Letters to the Editor

SNMMI Newsline

In this issue

Issue highlights

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