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Journal of Nuclear Medicine

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Research ArticleClinical Investigation

Imaging Pituitary Vasopressin 1B Receptor in Humans with the PET Radiotracer 11C-TASP699

Mika Naganawa, Nabeel B. Nabulsi, David Matuskey, Shannan Henry, Jim Ropchan, Shu-Fei Lin, Hong Gao, Richard Pracitto, David Labaree, Ming-Rong Zhang, Tetsuya Suhara, Izumi Nishino, Helene Sabia, Satoshi Ozaki, Yiyun Huang and Richard E. Carson
Journal of Nuclear Medicine April 2022, 63 (4) 609-614; DOI: https://doi.org/10.2967/jnumed.121.262430
Mika Naganawa
1Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut;
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Nabeel B. Nabulsi
1Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut;
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David Matuskey
1Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut;
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Shannan Henry
1Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut;
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Jim Ropchan
1Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut;
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Shu-Fei Lin
1Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut;
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Hong Gao
1Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut;
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Richard Pracitto
1Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut;
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David Labaree
1Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut;
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Ming-Rong Zhang
2National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan;
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Tetsuya Suhara
2National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan;
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Izumi Nishino
3Taisho Pharmaceutical Co., Ltd., Tokyo, Japan; and
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Helene Sabia
4Taisho Pharmaceutical R&D Inc., Morristown, New Jersey
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Satoshi Ozaki
4Taisho Pharmaceutical R&D Inc., Morristown, New Jersey
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Yiyun Huang
1Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut;
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Richard E. Carson
1Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut;
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Journal of Nuclear Medicine: 63 (4)
Journal of Nuclear Medicine
Vol. 63, Issue 4
April 1, 2022
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Imaging Pituitary Vasopressin 1B Receptor in Humans with the PET Radiotracer 11C-TASP699
Mika Naganawa, Nabeel B. Nabulsi, David Matuskey, Shannan Henry, Jim Ropchan, Shu-Fei Lin, Hong Gao, Richard Pracitto, David Labaree, Ming-Rong Zhang, Tetsuya Suhara, Izumi Nishino, Helene Sabia, Satoshi Ozaki, Yiyun Huang, Richard E. Carson
Journal of Nuclear Medicine Apr 2022, 63 (4) 609-614; DOI: 10.2967/jnumed.121.262430

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Imaging Pituitary Vasopressin 1B Receptor in Humans with the PET Radiotracer 11C-TASP699
Mika Naganawa, Nabeel B. Nabulsi, David Matuskey, Shannan Henry, Jim Ropchan, Shu-Fei Lin, Hong Gao, Richard Pracitto, David Labaree, Ming-Rong Zhang, Tetsuya Suhara, Izumi Nishino, Helene Sabia, Satoshi Ozaki, Yiyun Huang, Richard E. Carson
Journal of Nuclear Medicine Apr 2022, 63 (4) 609-614; DOI: 10.2967/jnumed.121.262430
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  • First-in-Human Study of 18F-Labeled PET Tracer for Glutamate AMPA Receptor [18F]K-40: A Derivative of [11C]K-2
  • Detection of HER2-Low Lesions Using HER2-Targeted PET Imaging in Patients with Metastatic Breast Cancer: A Paired HER2 PET and Tumor Biopsy Analysis
  • [11C]Carfentanil PET Whole-Body Imaging of μ-Opioid Receptors: A First in-Human Study
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Keywords

  • PET
  • kinetic modeling
  • receptor imaging
  • pituitary
  • vasopressin V1B receptor
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