Journal of Nuclear Medicine: 63 (4)

April 1, 2022; Volume 63,Issue 4

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine April 1, 2022, 63 (4) 12A;

Discussions with Leaders

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Leadership in Patient Advocacy
Josh Mailman and Thomas A. Hope

Journal of Nuclear Medicine April 1, 2022, 63 (4) 497-499; DOI: https://doi.org/10.2967/jnumed.122.263989

The State of The Art

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Nuclear Medicine and Artificial Intelligence: Best Practices for Algorithm Development
Tyler J. Bradshaw, Ronald Boellaard, Joyita Dutta, Abhinav K. Jha, Paul Jacobs, Quanzheng Li, Chi Liu, Arkadiusz Sitek, Babak Saboury, Peter J.H. Scott, Piotr J. Slomka, John J. Sunderland, Richard L. Wahl, Fereshteh Yousefirizi, Sven Zuehlsdorff, Arman Rahmim and Irène Buvat

Journal of Nuclear Medicine April 1, 2022, 63 (4) 500-510; DOI: https://doi.org/10.2967/jnumed.121.262567

Hot Topics

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Virtual Biopsy: Just an AI Software or a Medical Procedure?
Jacob M. Murray, Bodo Wiegand, Boris Hadaschik, Ken Herrmann and Jens Kleesiek

Journal of Nuclear Medicine April 1, 2022, 63 (4) 511-513; DOI: https://doi.org/10.2967/jnumed.121.263749

Continuing Education

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Principles of Tracer Kinetic Analysis in Oncology, Part II: Examples and Future Directions
Austin R. Pantel, Varsha Viswanath, Mark Muzi, Robert K. Doot and David A. Mankoff

Journal of Nuclear Medicine April 1, 2022, 63 (4) 514-521; DOI: https://doi.org/10.2967/jnumed.121.263519

Oncology

Clinical
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  Impact of ¹⁸F-FET PET/MRI on Clinical Management of Brain Tumor Patients
  Cornelia Brendle, Caroline Maier, Benjamin Bender, Jens Schittenhelm, Frank Paulsen, Mirjam Renovanz, Constantin Roder, Salvador Castaneda-Vega, Ghazaleh Tabatabai, Ulrike Ernemann and Christian la Fougère
  
  Journal of Nuclear Medicine April 1, 2022, 63 (4) 522-527; DOI: https://doi.org/10.2967/jnumed.121.262051
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  Phase I Trial of ^99mTc-(HE)₃-G3, a DARPin-Based Probe for Imaging of HER2 Expression in Breast Cancer
  Olga Bragina, Vladimir Chernov, Alexey Schulga, Elena Konovalova, Eugeniy Garbukov, Anzhelika Vorobyeva, Anna Orlova, Liubov Tashireva, Jens Sörensen, Roman Zelchan, Anna Medvedeva, Sergey Deyev and Vladimir Tolmachev
  
  Journal of Nuclear Medicine April 1, 2022, 63 (4) 528-535; DOI: https://doi.org/10.2967/jnumed.121.262542
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  First-in-Humans Evaluation of a PD-L1–Binding Peptide PET Radiotracer in Non–Small Cell Lung Cancer Patients
  Xin Zhou, Jinquan Jiang, Xue Yang, Teli Liu, Jin Ding, Sridhar Nimmagadda, Martin G. Pomper, Hua Zhu, Jun Zhao, Zhi Yang and Nan Li
  
  Journal of Nuclear Medicine April 1, 2022, 63 (4) 536-542; DOI: https://doi.org/10.2967/jnumed.121.262045
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  PET-Based Staging Is Cost-Effective in Early-Stage Follicular Lymphoma
  Andrea C. Lo, Lyndon P. James, Anca Prica, Adam Raymakers, Stuart Peacock, Melody Qu, Alex V. Louie, Kerry J. Savage, Laurie H. Sehn, David Hodgson, Joanna C. Yang, Hans T.T. Eich, Andrew Wirth and M.G. Myriam Hunink
  
  Journal of Nuclear Medicine April 1, 2022, 63 (4) 543-548; DOI: https://doi.org/10.2967/jnumed.121.262324
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  Combined Metabolically Active Tumor Volume and Early Metabolic Response Improve Outcome Prediction in Metastatic Colorectal Cancer
  Erwin Woff, Lisa Salvatore, Federica Marmorino, Dario Genovesi, Gabriela Critchi, Thomas Guiot, Lieveke Ameye, Francesco Sclafani, Alain Hendlisz and Patrick Flamen
  
  Journal of Nuclear Medicine April 1, 2022, 63 (4) 549-555; DOI: https://doi.org/10.2967/jnumed.120.245357
- BRIEF COMMUNICATION
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    Hepatic Artery Injection of ¹³¹I-Metuximab Combined with Transcatheter Arterial Chemoembolization for Unresectable Hepatocellular Carcinoma: A Prospective Nonrandomized, Multicenter Clinical Trial
    Hui Chen, Gang Nan, Ding Wei, Ren-You Zhai, Ming Huang, Wu-Wei Yang, Bao-Cai Xing, Xu Zhu, Hai-Feng Xu, Xiao-Dong Wang, Xiao-Yong Zhang, Bao-Rang Zhu, Peng Liu, Guang Cao, Song Gao, Chun-Yi Hao, Ren-Jie Yang, Jian-Hai Guo, Xin Zhang, Kun Gao, Kun Wang, Jian-Feng Wang, Zi-Yu Li, Lin-Zhong Zhu, Rong Ding, Jing Li, Ling Zhao, Yu-Jun Shao, Hai-Chun Liu, Jie-Lai Xia, Ling Wang, Ling-Min Kong, Zhi-Nan Chen and Huijie Bian
    
    Journal of Nuclear Medicine April 1, 2022, 63 (4) 556-559; DOI: https://doi.org/10.2967/jnumed.121.262136

Theranostics

Clinical
- FEATURED ARTICLE OF THE MONTH
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    ¹⁷⁷Lu-PSMA-617 and Idronoxil in Men with End-Stage Metastatic Castration-Resistant Prostate Cancer (LuPIN): Patient Outcomes and Predictors of Treatment Response in a Phase I/II Trial
    Sarennya Pathmanandavel, Megan Crumbaker, Andrew O. Yam, Andrew Nguyen, Christopher Rofe, Elizabeth Hovey, Craig Gedye, Edmond M. Kwan, Christine Hauser, Arun A. Azad, Peter Eu, Andrew J. Martin, Anthony M. Joshua and Louise Emmett
    
    Journal of Nuclear Medicine April 1, 2022, 63 (4) 560-566; DOI: https://doi.org/10.2967/jnumed.121.262552
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  A Comprehensive Assessment of ⁶⁸Ga-PSMA-11 PET in Biochemically Recurrent Prostate Cancer: Results from a Prospective Multicenter Study on 2,005 Patients
  Monica Abghari-Gerst, Wesley R. Armstrong, Kathleen Nguyen, Jeremie Calais, Johannes Czernin, David Lin, Namasvi Jariwala, Melissa Rodnick, Thomas A. Hope, Jason Hearn, Jeffrey S. Montgomery, Ajjai Alva, Zachery R. Reichert, Daniel E. Spratt, Timothy D. Johnson, Peter J.H. Scott and Morand Piert
  
  Journal of Nuclear Medicine April 1, 2022, 63 (4) 567-572; DOI: https://doi.org/10.2967/jnumed.121.262412
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  An ⁸⁹Zr-Labeled PSMA Tracer for PET/CT Imaging of Prostate Cancer Patients
  Felix Dietlein, Carsten Kobe, Sergio Muñoz Vázquez, Thomas Fischer, Heike Endepols, Melanie Hohberg, Manuel Reifegerst, Bernd Neumaier, Klaus Schomäcker, Alexander E. Drzezga and Markus Dietlein
  
  Journal of Nuclear Medicine April 1, 2022, 63 (4) 573-583; DOI: https://doi.org/10.2967/jnumed.121.262290
Basic
- Open Access
  First In Vivo and Phantom Imaging of Cyclotron-Produced ¹³³La as a Theranostic Radionuclide for ²²⁵Ac and ¹³⁵La
  Bryce J.B. Nelson, Simon Ferguson, Melinda Wuest, John Wilson, M. John M. Duke, Susan Richter, Hans Soenke-Jans, Jan D. Andersson, Freimut Juengling and Frank Wuest
  
  Journal of Nuclear Medicine April 1, 2022, 63 (4) 584-590; DOI: https://doi.org/10.2967/jnumed.121.262459

AI/Advanced Image Analysis

Basic
- FEATURED BASIC SCIENCE ARTICLE
  - Open Access
    Blind Image Restoration Enhances Digital Autoradiographic Imaging of Radiopharmaceutical Tissue Distribution
    Lu Peng, Benabdallah Nadia, Jiang Wen, Brian W. Simons, Zhang Hanwen, Robert F. Hobbs, Ulmert David, Brian C. Baumann, Russell K. Pachynski, Abhinav K. Jha and Daniel L.J. Thorek
    
    Journal of Nuclear Medicine April 1, 2022, 63 (4) 591-597; DOI: https://doi.org/10.2967/jnumed.121.262270

Covid Communications

- BRIEF COMMUNICATION
  - Open Access
    Experience with a Perfusion-Only Screening Protocol for Evaluation of Pulmonary Embolism During the COVID-19 Pandemic Surge
    Arun Kumar, Renée M. Moadel, Linda B. Haramati, Kenny Ye, Leonard M. Freeman and Lionel S. Zuckier
    
    Journal of Nuclear Medicine April 1, 2022, 63 (4) 598-601; DOI: https://doi.org/10.2967/jnumed.121.262580

Cardiovascular

Clinical
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  ¹⁸F-FDG PET in Myocardial Viability Assessment: A Practical and Time-Efficient Protocol
  Joyce Mhlanga, Paul Derenoncourt, Adeel Haq, Anita Bhandiwad, Richard Laforest, Barry A. Siegel, Farrokh Dehdashti, Robert J. Gropler and Thomas H. Schindler
  
  Journal of Nuclear Medicine April 1, 2022, 63 (4) 602-608; DOI: https://doi.org/10.2967/jnumed.121.262432

Endocrinology

Clinical
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  Imaging Pituitary Vasopressin 1B Receptor in Humans with the PET Radiotracer ¹¹C-TASP699
  Mika Naganawa, Nabeel B. Nabulsi, David Matuskey, Shannan Henry, Jim Ropchan, Shu-Fei Lin, Hong Gao, Richard Pracitto, David Labaree, Ming-Rong Zhang, Tetsuya Suhara, Izumi Nishino, Helene Sabia, Satoshi Ozaki, Yiyun Huang and Richard E. Carson
  
  Journal of Nuclear Medicine April 1, 2022, 63 (4) 609-614; DOI: https://doi.org/10.2967/jnumed.121.262430

Neurology

Clinical
- SPECIAL CONTRIBUTION
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    A Path to Qualification of PET/MRI Scanners for Multicenter Brain Imaging Studies: Evaluation of MRI-Based Attenuation Correction Methods Using a Patient Phantom
    Ciprian Catana, Richard Laforest, Hongyu An, Fernando Boada, Tuoyu Cao, David Faul, Bjoern Jakoby, Floris P. Jansen, Bradley J. Kemp, Paul E. Kinahan, Peder Larson, Michael A. Levine, Piotr Maniawski, Osama Mawlawi, Jonathan E. McConathy, Alan B. McMillan, Julie C. Price, Abhejit Rajagopal, John Sunderland, Patrick Veit-Haibach, Kristen A. Wangerin, Chunwei Ying and Thomas A. Hope
    
    Journal of Nuclear Medicine April 1, 2022, 63 (4) 615-621; DOI: https://doi.org/10.2967/jnumed.120.261881

Physics and Instrumentation

Clinical
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  Whole-Body Parametric Imaging of ¹⁸F-FDG PET Using uEXPLORER with Reduced Scanning Time
  Yaping Wu, Tao Feng, Yizhang Zhao, Tianyi Xu, Fangfang Fu, Zhun Huang, Nan Meng, Hongdi Li, Fengmin Shao and Meiyun Wang
  
  Journal of Nuclear Medicine April 1, 2022, 63 (4) 622-628; DOI: https://doi.org/10.2967/jnumed.120.261651

Molecular Imaging

Basic
- You have access
  Influence of Fc Modifications and IgG Subclass on Biodistribution of Humanized Antibodies Targeting L1CAM
  Sai Kiran Sharma, Maya Suzuki, Hong Xu, Joshua A. Korsen, Zachary Samuels, Hongfen Guo, Brandon Nemieboka, Alessandra Piersigilli, Kimberly J. Edwards, Nai-Kong V. Cheung and Jason S. Lewis
  
  Journal of Nuclear Medicine April 1, 2022, 63 (4) 629-636; DOI: https://doi.org/10.2967/jnumed.121.262383

SNMMI Newsline

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SNMMI Newsline
Journal of Nuclear Medicine April 1, 2022, 63 (4) 15N-26N;
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Medical Societies Seek Medicare Reform Collaboration
Journal of Nuclear Medicine April 1, 2022, 63 (4) 15N;
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NRC Vetoes T&E Changes; Approves ⁸²Rb and Emerging Tech Modernization
Journal of Nuclear Medicine April 1, 2022, 63 (4) 16N;
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SNMMI Calls for Expanded Coverage/Reimbursement of Amyloid PET
Journal of Nuclear Medicine April 1, 2022, 63 (4) 17N;
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ABNM: Nuclear Medicine In-Training Examination Goes Virtual
Leonie Gordon

Journal of Nuclear Medicine April 1, 2022, 63 (4) 18N;
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SNMMI Leadership Update: SNMMI Meetings Back in Full Swing
Virginia Pappas

Journal of Nuclear Medicine April 1, 2022, 63 (4) 19N;
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Newsbriefs
Journal of Nuclear Medicine April 1, 2022, 63 (4) 20N-21N;
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From the Literature
Journal of Nuclear Medicine April 1, 2022, 63 (4) 22N-26N;

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Table of Contents

This Month in JNM

Discussions with Leaders

The State of The Art

Hot Topics

Continuing Education

Oncology

Clinical

BRIEF COMMUNICATION

Theranostics

Clinical

FEATURED ARTICLE OF THE MONTH

Basic

AI/Advanced Image Analysis

Basic

FEATURED BASIC SCIENCE ARTICLE

Covid Communications

BRIEF COMMUNICATION

Cardiovascular

Clinical

Endocrinology

Clinical

Neurology

Clinical

SPECIAL CONTRIBUTION

Physics and Instrumentation

Clinical

Molecular Imaging

Basic

SNMMI Newsline

In this issue

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