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Journal of Nuclear Medicine

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Research ArticleOncology

Automated Segmentation of Baseline Metabolic Total Tumor Burden in Diffuse Large B-Cell Lymphoma: Which Method Is Most Successful? A Study on Behalf of the PETRA Consortium

Sally F. Barrington, Ben G.J.C. Zwezerijnen, Henrica C.W. de Vet, Martijn W. Heymans, N. George Mikhaeel, Coreline N. Burggraaff, Jakoba J. Eertink, Lucy C. Pike, Otto S. Hoekstra, Josée M. Zijlstra and Ronald Boellaard
Journal of Nuclear Medicine March 2021, 62 (3) 332-337; DOI: https://doi.org/10.2967/jnumed.119.238923
Sally F. Barrington
1King’s College London and Guy’s and St. Thomas’ PET Center, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
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Ben G.J.C. Zwezerijnen
2Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
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Henrica C.W. de Vet
3Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
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Martijn W. Heymans
3Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
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N. George Mikhaeel
4Department of Clinical Oncology, Guy’s and St. Thomas’ NHS Foundation Trust and School of Cancer and Pharmaceutical Sciences, King’s College London, London, United Kingdom; and
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Coreline N. Burggraaff
5Department of Hematology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
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Jakoba J. Eertink
5Department of Hematology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
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Lucy C. Pike
1King’s College London and Guy’s and St. Thomas’ PET Center, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom
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Otto S. Hoekstra
2Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
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Josée M. Zijlstra
5Department of Hematology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
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Ronald Boellaard
2Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
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Journal of Nuclear Medicine: 62 (3)
Journal of Nuclear Medicine
Vol. 62, Issue 3
March 1, 2021
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Automated Segmentation of Baseline Metabolic Total Tumor Burden in Diffuse Large B-Cell Lymphoma: Which Method Is Most Successful? A Study on Behalf of the PETRA Consortium
Sally F. Barrington, Ben G.J.C. Zwezerijnen, Henrica C.W. de Vet, Martijn W. Heymans, N. George Mikhaeel, Coreline N. Burggraaff, Jakoba J. Eertink, Lucy C. Pike, Otto S. Hoekstra, Josée M. Zijlstra, Ronald Boellaard
Journal of Nuclear Medicine Mar 2021, 62 (3) 332-337; DOI: 10.2967/jnumed.119.238923

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Automated Segmentation of Baseline Metabolic Total Tumor Burden in Diffuse Large B-Cell Lymphoma: Which Method Is Most Successful? A Study on Behalf of the PETRA Consortium
Sally F. Barrington, Ben G.J.C. Zwezerijnen, Henrica C.W. de Vet, Martijn W. Heymans, N. George Mikhaeel, Coreline N. Burggraaff, Jakoba J. Eertink, Lucy C. Pike, Otto S. Hoekstra, Josée M. Zijlstra, Ronald Boellaard
Journal of Nuclear Medicine Mar 2021, 62 (3) 332-337; DOI: 10.2967/jnumed.119.238923
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  • PET-Based Risk Stratification in Primary Mediastinal B-Cell Lymphoma: A Comparative Analysis of Different Segmentation Methods in the IELSG37 Trial Patient Cohort
  • Validation of an Artificial Intelligence-Based Prediction Model Using 5 External PET/CT Datasets of Diffuse Large B-Cell Lymphoma
  • International Benchmark for Total Metabolic Tumor Volume Measurement in Baseline 18F-FDG PET/CT of Lymphoma Patients: A Milestone Toward Clinical Implementation
  • Is 18F-FDG Metabolic Tumor Volume in Lymphoma Really Happening?
  • Prognostic Value of 18F-FDG PET Radiomics Features at Baseline in PET-Guided Consolidation Strategy in Diffuse Large B-Cell Lymphoma: A Machine-Learning Analysis from the GAINED Study
  • Stacking Ensemble Learning-Based [18F]FDG PET Radiomics for Outcome Prediction in Diffuse Large B-Cell Lymphoma
  • Technologist-Based Implementation of Total Metabolic Tumor Volume into Clinical Practice
  • The Impact of Semiautomatic Segmentation Methods on Metabolic Tumor Volume, Intensity, and Dissemination Radiomics in 18F-FDG PET Scans of Patients with Classical Hodgkin Lymphoma
  • 18F-FDG PET Improves Baseline Clinical Predictors of Response in Diffuse Large B-Cell Lymphoma: The HOVON-84 Study
  • Quantitative Radiomics Features in Diffuse Large B-Cell Lymphoma: Does Segmentation Method Matter?
  • Interobserver Agreement on Automated Metabolic Tumor Volume Measurements of Deauville Score 4 and 5 Lesions at Interim 18F-FDG PET in Diffuse Large B-Cell Lymphoma
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Keywords

  • lymphoma
  • metabolic tumor volume
  • PET
  • standardization
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