Journal of Nuclear Medicine: 62 (12)

December 1, 2021; Volume 62,Issue 12

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine December 1, 2021, 62 (12) 10A;

Discussions with Leaders

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Molecular Imaging Leadership in Academia and Industry
Mark Mintun and David Mankoff

Journal of Nuclear Medicine December 1, 2021, 62 (12) 1657-1659; DOI: https://doi.org/10.2967/jnumed.121.263451

The State of The Art

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Radionuclide Therapy in Prostate Cancer: From Standalone to Combination PSMA Theranostics
Shahneen Sandhu, Christina Guo and Michael S. Hofman

Journal of Nuclear Medicine December 1, 2021, 62 (12) 1660-1668; DOI: https://doi.org/10.2967/jnumed.120.243295

Hot Topics

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Radioembolization Versus Bland or Chemoembolization for Liver-Dominant Neuroendocrine Tumors: Is It an Either/Or Question?
Strosberg Jonathan, Ghassan El-Haddad, Taymeyah Al-Toubah, Diane Reidy-Lagunes, Etay Ziv, Armeen Mahvash, Arvind Dasari, Philip A. Philip and Michael C. Soulen

Journal of Nuclear Medicine December 1, 2021, 62 (12) 1669-1671; DOI: https://doi.org/10.2967/jnumed.121.263041

Focus on Molecular Imaging

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Building the Bridge: Molecular Imaging Biomarkers for 21st Century Cancer Therapies
Mark A. Sellmyer, Iris K. Lee and David A. Mankoff

Journal of Nuclear Medicine December 1, 2021, 62 (12) 1672-1676; DOI: https://doi.org/10.2967/jnumed.121.262484

Oncology

Clinical
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  Determining the Axillary Nodal Status with 4 Current Imaging Modalities, Including ¹⁸F-FDG PET/MRI, in Newly Diagnosed Breast Cancer: A Comparative Study Using Histopathology as the Reference Standard
  Janna Morawitz, Nils-Martin Bruckmann, Frederic Dietzel, Tim Ullrich, Ann-Kathrin Bittner, Oliver Hoffmann, Svjetlana Mohrmann, Lena Häberle, Marc Ingenwerth, Lale Umutlu, Wolfgang Peter Fendler, Tanja Fehm, Ken Herrmann, Gerald Antoch, Lino Morris Sawicki and Julian Kirchner
  
  Journal of Nuclear Medicine December 1, 2021, 62 (12) 1677-1683; DOI: https://doi.org/10.2967/jnumed.121.262009
- Open Access
  Prognostic Value of Postinduction Chemotherapy Volumetric PET/CT Parameters for Stage IIIA or IIIB Non–Small Cell Lung Cancer Patients Receiving Definitive Chemoradiotherapy
  Maja Guberina, Christoph Pöttgen, Martin Metzenmacher, Marcel Wiesweg, Martin Schuler, Clemens Aigner, Till Ploenes, Lale Umutlu, Thomas Gauler, Kaid Darwiche, Georgios Stamatis, Dirk Theegarten, Hubertus Hautzel, Walter Jentzen, Nika Guberina, Ken Herrmann, Wilfried E.E. Eberhardt and Martin Stuschke
  
  Journal of Nuclear Medicine December 1, 2021, 62 (12) 1684-1691; DOI: https://doi.org/10.2967/jnumed.120.260646
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  Transarterial Radioembolization Versus Systemic Treatment for Hepatocellular Carcinoma with Macrovascular Invasion: Analysis of the U.S. National Cancer Database
  Joseph C. Ahn, Marie Lauzon, Michael Luu, Marc L. Friedman, Kambiz Kosari, Nicholas Nissen, Shelly C. Lu, Lewis R. Roberts, Amit G. Singal and Ju Dong Yang
  
  Journal of Nuclear Medicine December 1, 2021, 62 (12) 1692-1701; DOI: https://doi.org/10.2967/jnumed.121.261954
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  Minimal Extrathyroidal Extension in Papillary Thyroid Microcarcinoma Is an Independent Risk Factor for Relapse Through Lymph Node and Distant Metastases
  Robert Seifert, Michael Schäfers, Barbara Heitplatz, Laura Kerschke, Burkhard Riemann and Benjamin Noto
  
  Journal of Nuclear Medicine December 1, 2021, 62 (12) 1702-1709; DOI: https://doi.org/10.2967/jnumed.121.261898

Theranostics

Clinical
- EDITORIAL
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    Bringing VISION to Nuclear Medicine: Accelerating Evidence and Changing Paradigms with Theranostics
    Michael S. Hofman
    
    Journal of Nuclear Medicine December 1, 2021, 62 (12) 1710-1711; DOI: https://doi.org/10.2967/jnumed.121.262890
- Open Access
  Symptom Diaries of Patients with Midgut Neuroendocrine Tumors Treated with ¹⁷⁷Lu-DOTATATE
  Jonathan R. Strosberg, Rajaventhan Srirajaskanthan, Ghassan El-Haddad, Edward M. Wolin, Beth A. Chasen, Matthew H. Kulke, David L. Bushnell, Martyn E. Caplin, Richard P. Baum, Andrew E. Hendifar, Kjell Öberg, Philippe Ruszniewski, Paola Santoro, Per Broberg, Oscar R. Leeuwenkamp, Eric P. Krenning and for the NETTER-1 study group
  
  Journal of Nuclear Medicine December 1, 2021, 62 (12) 1712-1718; DOI: https://doi.org/10.2967/jnumed.120.258897
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  Detection Efficacy of ¹⁸F‐rhPSMA‐7.3 PET/CT and Impact on Management in Patients with Biochemical Recurrence of Prostate Cancer After Radical Prostatectomy and Before Potential Salvage Treatment
  Isabel Rauscher, Amir Karimzadeh, Kilian Schiller, Thomas Horn, Calogero D’Alessandria, Charlott Franz, Hannah Wörther, Noemi Nguyen, Stephanie E. Combs, Wolfgang A. Weber and Matthias Eiber
  
  Journal of Nuclear Medicine December 1, 2021, 62 (12) 1719-1726; DOI: https://doi.org/10.2967/jnumed.120.260091
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  A Phase II, Open-Label Study to Assess Safety and Management Change Using ⁶⁸Ga-THP PSMA PET/CT in Patients with High-Risk Primary Prostate Cancer or Biochemical Recurrence After Radical Treatment: The PRONOUNCED Study
  Asim Afaq, Heather Payne, Reena Davda, John Hines, Gary J.R. Cook, Marie Meagher, Dimitrios Priftakis, Victoria S. Warbey, Anand Kelkar, Clement Orczyk, Anita Mitra, Sarah Needleman, Michael Ferris, Greg Mullen and Jamshed Bomanji
  
  Journal of Nuclear Medicine December 1, 2021, 62 (12) 1727-1734; DOI: https://doi.org/10.2967/jnumed.120.257527
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  Tumor Detection of ¹⁸F-PSMA-1007 in the Prostate Gland in Patients with Prostate Cancer Using Prostatectomy Specimens as Reference Method
  Elin Trägårdh, Athanasios Simoulis, Anders Bjartell and Jonas Jögi
  
  Journal of Nuclear Medicine December 1, 2021, 62 (12) 1735-1740; DOI: https://doi.org/10.2967/jnumed.121.261993
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  Assessing Response to ¹⁷⁷Lu-PSMA Radioligand Therapy Using Modified PSMA PET Progression Criteria
  Kerstin Michalski, Claudius Klein, Tonio Brüggemann, Philipp T. Meyer, Cordula A. Jilg and Juri Ruf
  
  Journal of Nuclear Medicine December 1, 2021, 62 (12) 1741-1746; DOI: https://doi.org/10.2967/jnumed.120.260836
- BRIEF COMMUNICATION
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    PSMA PET for the Assessment of Metastatic Hormone-Sensitive Prostate Cancer Volume of Disease
    Francesco Barbato, Wolfgang P. Fendler, Isabel Rauscher, Ken Herrmann, Axel Wetter, Justin Ferdinandus, Robert Seifert, Michael Nader, Kambiz Rahbar, Boris Hadaschik, Matthias Eiber, Andrei Gafita and Manuel Weber
    
    Journal of Nuclear Medicine December 1, 2021, 62 (12) 1747-1750; DOI: https://doi.org/10.2967/jnumed.121.262120

Radionuclide Therapy

Basic
- FEATURED BASIC SCIENCE ARTICLE
  - Open Access
    Improved ²²³Ra Therapy with Combination Epithelial Sodium Channel Blockade
    Diane S. Abou, Amanda Fears, Lucy Summer, Mark Longtine, Nadia Benabdallah, Ryan C. Riddle, David Ulmert, Jeff M. Michalski, Richard L. Wahl, Denise Chesner, Michele Doucet, Nicholas C. Zachos, Brian W. Simons and Daniel L.J. Thorek
    
    Journal of Nuclear Medicine December 1, 2021, 62 (12) 1751-1758; DOI: https://doi.org/10.2967/jnumed.121.261977

Cardiovascular

Clinical
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  Comparison of the Effect of Three Different Dietary Modifications on Myocardial Suppression in ¹⁸F-FDG PET/CT Evaluation of Patients for Suspected Cardiac Sarcoidosis
  Can Özütemiz, Yasemin Koksel, Jerry W. Froelich, Nathan Rubin, Maneesh Bhargava, Henri Roukoz, Rebecca Cogswell, Jeremy Markowitz, David M. Perlman and Daniel Steinberger
  
  Journal of Nuclear Medicine December 1, 2021, 62 (12) 1759-1767; DOI: https://doi.org/10.2967/jnumed.121.261981
- Open Access
  MRI-Guided Motion-Corrected PET Image Reconstruction for Cardiac PET/MRI
  Camila Munoz, Sam Ellis, Stephan G. Nekolla, Karl P. Kunze, Teresa Vitadello, Radhouene Neji, Rene M. Botnar, Julia A. Schnabel, Andrew J. Reader and Claudia Prieto
  
  Journal of Nuclear Medicine December 1, 2021, 62 (12) 1768-1774; DOI: https://doi.org/10.2967/jnumed.120.254235

Neurology

Clinical
- FEATURED ARTICLE OF THE MONTH
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    Dynamic ¹⁸F-FPCIT PET: Quantification of Parkinson Disease Metabolic Networks and Nigrostriatal Dopaminergic Dysfunction in a Single Imaging Session
    Shichun Peng, Chris Tang, Katharina Schindlbeck, Yaacov Rydzinski, Vijay Dhawan, Phoebe G. Spetsieris, Yilong Ma and David Eidelberg
    
    Journal of Nuclear Medicine December 1, 2021, 62 (12) 1775-1782; DOI: https://doi.org/10.2967/jnumed.120.257345
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  Frontal Hypometabolism in Neurocognitive Disorder with Behavioral Disturbance
  Christine Bastin, Mohamed Ali Bahri, Claire Bernard, Roland Hustinx and Eric Salmon
  
  Journal of Nuclear Medicine December 1, 2021, 62 (12) 1783-1788; DOI: https://doi.org/10.2967/jnumed.120.260497
Basic
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  A Noninvasive Method for Quantifying Cerebral Metabolic Rate of Oxygen by Hybrid PET/MRI: Validation in a Porcine Model
  Lucas Narciso, Tracy Ssali, Linshan Liu, Heather Biernaski, John Butler, Laura Morrison, Jennifer Hadway, Jeffrey Corsaut, Justin W. Hicks, Michael C. Langham, Felix W. Wehrli, Hidehiro Iida and Keith St Lawrence
  
  Journal of Nuclear Medicine December 1, 2021, 62 (12) 1789-1796; DOI: https://doi.org/10.2967/jnumed.120.260521

Molecular Imaging

Basic
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  Patient Size-Dependent Dosimetry Methodology Applied to ¹⁸F-FDG Using New ICRP Mesh Phantoms
  Lukas M. Carter, Chansoo Choi, Simone Krebs, Bradley J. Beattie, Chan Hyeong Kim, Heiko Schoder, Wesley E. Bolch and Adam L. Kesner
  
  Journal of Nuclear Medicine December 1, 2021, 62 (12) 1805-1814; DOI: https://doi.org/10.2967/jnumed.120.256719

Radiobiology/Dosimetry

Basic
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  Mesothelin/CD3 Half-Life–Extended Bispecific T-Cell Engager Molecule Shows Specific Tumor Uptake and Distributes to Mesothelin and CD3-Expressing Tissues
  Frans V. Suurs, Grit Lorenczewski, Julie M. Bailis, Sabine Stienen, Matthias Friedrich, Fei Lee, Bert van der Vegt, Elisabeth G.E. de Vries, Derk Jan A. de Groot and Marjolijn N. Lub-de Hooge
  
  Journal of Nuclear Medicine December 1, 2021, 62 (12) 1797-1804; DOI: https://doi.org/10.2967/jnumed.120.259036

Infectious Disease

Clinical
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  Appropriate Use Criteria for the Use of Nuclear Medicine in Musculoskeletal Infection Imaging
  Christopher J. Palestro, Alicia Clark, Erin E. Grady, Sherif Heiba, Ora Israel, Alan Klitzke, Charito Love, Mike Sathekge, Treves Ted and Tracy L. Yarbrough
  
  Journal of Nuclear Medicine December 1, 2021, 62 (12) 1815-1831; DOI: https://doi.org/10.2967/jnumed.121.262579

Letters To The Editor

Open Access
Houdini’s Illusions: Some Acts Are Not What They Seem to Be
Roelof J. Bennink, Mathias Prokop, Andor W. J. M. Glaudemans, Liesbeth Peters-Bax, Jasper H. G. Helthuis, Arthur Adams, Peter R. Kornaat, Adriaan A. Lammertsma and Lenka M. Pereira Arias-Bouda

Journal of Nuclear Medicine December 1, 2021, 62 (12) 1832; DOI: https://doi.org/10.2967/jnumed.121.262631
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Cut Point Identification of Continuous Biomarkers: A Challenge That Goes Beyond Statistical Aspects
Paulo Schiavom Duarte

Journal of Nuclear Medicine December 1, 2021, 62 (12) 1833; DOI: https://doi.org/10.2967/jnumed.121.262905

SNMMI Newsline

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SNMMI Newsline
Journal of Nuclear Medicine December 1, 2021, 62 (12) 11N-22N;
Open Access
2021 SNMMI Highlights Lecture: Neuroscience
Julie Price

Journal of Nuclear Medicine December 1, 2021, 62 (12) 11N-17N;
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Interim Report on Provisional Requirements for Radionuclide Therapy
Journal of Nuclear Medicine December 1, 2021, 62 (12) 18N;
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SNMMI Mid-Winter and ACNM Annual Meeting Convene In-Person
Virginia Pappas

Journal of Nuclear Medicine December 1, 2021, 62 (12) 19N;
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Newsbriefs
Journal of Nuclear Medicine December 1, 2021, 62 (12) 20N-22N;

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Table of Contents

This Month in JNM

Discussions with Leaders

The State of The Art

Hot Topics

Focus on Molecular Imaging

Oncology

Clinical

Theranostics

Clinical

EDITORIAL

BRIEF COMMUNICATION

Radionuclide Therapy

Basic

FEATURED BASIC SCIENCE ARTICLE

Cardiovascular

Clinical

Neurology

Clinical

FEATURED ARTICLE OF THE MONTH

Basic

Molecular Imaging

Basic

Radiobiology/Dosimetry

Basic

Infectious Disease

Clinical

Letters To The Editor

SNMMI Newsline

In this issue

Issue highlights

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