Article Figures & Data
Figures
- FIGURE 1.
Overview of intraoperative SN removal and tumor-positive SNs.
- FIGURE 2.
Location of iliac SN resected after unmasking of surgeon to SPECT/CT.
Tables
Characteristic All patients (n = 25) Hybrid-tracer group (n = 15) Free-ICG group (n = 10) P Age at surgery (y) 65.4 (6.1) 64.3 (8.4) 67.4 (4.4) 0.247 PSA at diagnosis 8.6 (3.9) 9.1 (4.6) 7.7 (2.3) 0.383 PSA range at diagnosis (ng/mL) 2.7–22.5 2.7–22.5 4.31–12.04 Clinical stage 0.870 cT1c 5 4 1 cT2a 4 2 2 cT2b 3 1 2 cT2c 7 4 3 cT3a 5 3 2 cT3b 1 1 0 Biopsy Gleason sum 1.000 6 2 1 1 7 17 10 7 8 3 2 1 9 3 2 1 Prostate volume (mL) 50.2 (21) 48.1 (20.0) 52.4 (25.8) 0.641 Briganti score 16.6% (16.1) 16.6 (15.6) 16.6 (17.8) 0.996 Pathologic stage 0.596 pT2a 4 1 3 pT2c 14 9 5 pT3a 5 3 2 pT3b 1 1 0 pT4 1 1 0 Pathologic Gleason sum 0.194 6 3 3 0 7 15 7 8 8 3 3 0 9 2 2 2 Nodal status 1.00 pN0 19 11 8 pN1 6 4 2 Qualitative data are expressed as numbers; continuous data are expressed as mean followed by SD in parentheses.
Parameter All patients (n = 25) Hybrid-tracer group (n = 15) Free-ICG group (n = 10) SPECT/CT Total identified SNs 111 57 54 Mean SNs per patient 4.4 (SD, 2.5) 3.8 (SD, 1.8) 5.4 (SD, 3.0) SNs inside ePLND template 82 (73.9%) 50 (87.7%) 32 (59.3%) External iliac 26 16 10 Internal iliac 21 13 8 Obturator fossa 35 21 14 SNs outside ePLND template 29 (26.1%) 7 (12.3%) 22 (40.7%) Common iliac 12 4 8 Paravesical 3 3 0 Presacral 5 0 5 Pararectal 6 0 6 Inguinal 3 0 3 Data are numbers.
Parameter All patients (n = 25) Hybrid-tracer group (n = 15) Free-ICG group (n = 10) Resected SNs 114 58 56 SNs removed under fluorescence guidance 73 (64.0%) 44 (75.9%) 29 (51.8%) SNs per patient 4.6 (SD, 3.0) 3.8 (SD, 2.0) 5.6 (SD, 3.8) Fluorescent SNs removed inside ePLND template 56 (79.5%) 34 (77.3%) 22 (75.9%) Externa iliac 20 12 8 Internal iliac 11 7 4 Obturator fossa 25 15 10 Fluorescent SNs removed outside ePLND template 17 (23.3%) 10 (29.4%) 7 (24.1%) Common iliac 2 2 0 Marcille 0 0 0 Cloquet 0 0 0 Pararectal 5 0 5 Presacral 2 0 2 Umbilical ligament 8 8 0 Aorta bifurcation 0 0 0 Undefined 0 0 0 SNs resected during eLNPD 22 (19.3%) 7 (12.1%) 15 (26.8%) SNs identified after unmasking of SPECT 18 (15.8%) 6 (10.3%) 12 (21.4%) SNs removed after unmasking 1 — 1 SNs not removed after unmasking 17 7 10 Location Inside ePLND template (internal iliac) 3 2 1 Outside ePLND template Common iliac 4 3 1 Pararectal 8 2 6 Inguinal 2 — 2 Non-SNs removed under fluorescence guidance 21 8 13 Ex vivo imaging SNs that were fluorescent but not radioactive 14 0 14 Patients 7 (28%) 0 (0%) 7 (70%) Data are numbers.
Parameter All patients (n = 25) Hybrid-tracer group (n = 15) Free-ICG group (n = 10) Tumor-positive SNs Nodes 10 9 1 Patients 6 4 1 Non-SNs removed 320 177 143 Tumor-positive nodes in non-SNs Nodes 3 2 1 Patients 3 2 1 Tumor-positive nodes inside ePLND template External iliac 5 5* Internal iliac 2 2 Obturator fossa 3 2 1† Tumor-positive nodes outside ePLND template Marcille 1 1 Cloquet 1 1 Pararectal 1 1
